HUE027282T2 - Eljárás adagolókészülék elõállítására szer orális bevételéhez - Google Patents

Eljárás adagolókészülék elõállítására szer orális bevételéhez Download PDF

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Publication number
HUE027282T2
HUE027282T2 HUE07700757A HUE07700757A HUE027282T2 HU E027282 T2 HUE027282 T2 HU E027282T2 HU E07700757 A HUE07700757 A HU E07700757A HU E07700757 A HUE07700757 A HU E07700757A HU E027282 T2 HUE027282 T2 HU E027282T2
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agent
layers
layer
folded
sheet
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HUE07700757A
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Moshe Tsabari
Avner Balshey
Erez Yofe
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Intec Pharma Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074—Filling capsules; Related operations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A—HUMAN NECESSITIES
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    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/078—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of wafers or cachets
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    • A61K9/0012—Galenical forms characterised by the site of application
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    • B32B7/04—Interconnection of layers
    • B32B7/12—Interconnection of layers using interposed adhesives or interposed materials with bonding properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B63/00—Auxiliary devices, not otherwise provided for, for operating on articles or materials to be packaged
    • B65B63/04—Auxiliary devices, not otherwise provided for, for operating on articles or materials to be packaged for folding or winding articles, e.g. gloves or stockings
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    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B7/00—Closing containers or receptacles after filling
    • B65B7/16—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
    • B65B7/28—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
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    • Y10T156/1051—Methods of surface bonding and/or assembly therefor with permanent bending or reshaping or surface deformation of self sustaining lamina by folding

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  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
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  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Folding Of Thin Sheet-Like Materials, Special Discharging Devices, And Others (AREA)

Claims (8)

  1. Szabadalrtü igeaypontok
    1, Eljárás szer abagolé: készülék i^§2[k«lôâÈiMsâiæ oüris bevételre,: ássefy tartalmaz: 0) összesütkimk {41¾ egy vagy:több réteget {422,.423:. 424, 42b>, üardy tartalmaz egy rag* több âéyÿgstt szerrel vagy szert kibocsátó fomiuláciésval általában síkbeli összeállításba, hogy integrál? készüléket -432} akikrounk ki. (ri) össehííjtiak #203 m integrált adagoló készülékét {432}, hogy összehajtó?? integrált adagoló készüléke? (4S2) alakítsunk ki, amely első tengelyt határoz meg, ágy hogy az isszehaj&tí készüléknek ¢4112) egyre kisebb ráncai vasssak távolodva az első tengelytől, ügy, ixsgy egy részbe® keres? fee®sszí^tszéíeí adjon; és ílil) legalább részben kapszulázzuk {:430) a® összehajtott adagom készitlékt (48.2) egy alakra 1402}, amely alkaMss orális átlagolásra.
  2. 2. Az. L igénypont sxe.risi.ti eljárás, ahol a® egy vagy több réteg tartalmaz egy vagy több polimer anyagot, ahol az egy vagy több réteg íartahsksz egy jxillrnert vagy polimerek kombinációját, a polimer vagy polhnerek mindegyik réíegbgs lehetitek ugyanazok vagy különbözőek egy rrsásik rétegétől a készülékért beiül. % Az. I. vagy 2. igénypont szerinti eljárás, amely tartalmaz legalább egy rétege? szalag alakjában, asrsely aa egy vagy több réteg legalább egyikéhez kapcsolódik.
  3. 4. Aa 1-3. igénypontok bármelyike szerisrti eljárás, ahol az összeállítás tartalmazza az egy vagy több réteg integrációját laminál? készülék kialakítására.
  4. 5. Az 1-4. igénypontok bármelyike saerinti eljárás, amely tartalmazza két külső réteg összeállítását, amely első anyagból vatr és llrnkeiónális réteg: helbgl&iásat, a íuhkoíortális réteg tartalmaz legalább egy réteget, szalag alakjslbsm vagy több szalag: alakjában, amely második anyagból vas: és atstély tartalmazza « Szer vagy szer kilxtesáiő hmtonlációt. b. Az 1-5. igé&yfsMk bármelyiké szerinti öljáráís,: amely tartalmazza erősítő polimer kömpoxisió legalább egy rétegének: összeállítását, amelynek meebeníkal szilárdsága olyast, begy az adáfolő Mszülék kiktgíogatásakor, az erősítő jxdiraer kompíendő lehetővé les® a készülék mégísrtását lényégébe?? stet® összehajtott felépítésbe«. 7. A 3-6. igénypontok bármelyike szerinti eljárás, amely imtahasgí® leplább egy réteg összeállítását égy vagy több folytonos vagy nem fidytsmes szalag alakjában, amelynek vari egy vagy több rétege, asttely tarsaltíiazza a szesz vagy szeriMboesátdribrmsláeíét. & Az 1-7. .igéirypoKtrk hánttéiyiiké szedrét eljárás, ahol az: itstegtált: készülék tartalmaz ke; vagy több elemet, amely ki van választva a kél: vagy több réteg rágasztásü, lïepsgtése, volkamzálasa v agy sz.imereiése közül, hogy lehetővé tegye ezer· rétegek közötti integrációt. % A 8. igénypont szerinti: eljárás,; stately tartalmazza mtográsíős szer alkalmazását a két vagy több rétégé ágy hogy iaegköiMiyiíse a rétegek: közötti iístegrseiót,
  5. 10. Az 1)8;. igénypontok feársnelylke szermíi eljárás, ahol az összeállítás tartalmazza a következők legalább egyikét: * a szer vagy széf kibocsátó lormüláeié beágyazásit egy vagy Äh rétegbe;: - a szer bezárását iegíslább két réteg, közé:; - a. sæsr vapr szer kibocsátó: foratdiácieS kakától legalább egy pofeséf rnstiibrárt szegmensen belül; - g szer vagy szer kibocsátó íoranílácié kapcsolását a készülék egy vagy több rétegének s készülék, mm- vagy mikrorészecskék, por, folyadék vagy kotnpresszált szilárd anyagok vagy mátrix íélepinek legalább egyikéhez. Λ A 10. Igényport; szerinti eljárás, amely tartalmasad látitihálí készülék összeállítását;, steely iatiitimáz két külső jelegek mnely első míyaghől áll M egy vagy; több réteg kapSKiíiázásái, amely tartalmaz egy vagy több szalag®, amely egy második anyagból áll és íártaimazza a szert vágy szer kibocsátó íhmtuláe-d?.
  6. 12. A ií. igénypont szerinti eljárás, ahol a külső rétegek legalább egyike jjertmál? vagy perforációkat irattat nedvesítéskor. 13. A?; 1-12. igénypontok bármelyike szériát! eljárás, ahol a hajtogatás tartalmazza az integrált készülék manipulációját kompaktéit integrált készülékbe, amely legalább ötször kisebb méretű, teint az mtegrált készülék hajtogatása előtt.
  7. 14. Az 1-13. Igénypontok bármelyike szerinti eljárás gasztroretenciós orális átlagoló készülék előállítására.
  8. 15. Szer adagoló készülék {492} orális: bevételre, sorely tartáhnaz; Összehajtott: egy- vagy többrétegű integrált készüléket {452}, amely tartalmaz szer? vagy szer kibocsátó forttmláeióí, az Összehajtott integrált készülék legalább részben kapszulázva van egy kapszulán belül vagy az által, azzal jellemezve, bogy a szer asksgolo készülék m l - í:4, igényptmrák. bármelyike szerisíi eljárásstt! van elóálldva.
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