HU9401420D0 - Collagenase inhibitor - Google Patents

Collagenase inhibitor

Info

Publication number
HU9401420D0
HU9401420D0 HU9401420A HU9401420A HU9401420D0 HU 9401420 D0 HU9401420 D0 HU 9401420D0 HU 9401420 A HU9401420 A HU 9401420A HU 9401420 A HU9401420 A HU 9401420A HU 9401420 D0 HU9401420 D0 HU 9401420D0
Authority
HU
Hungary
Prior art keywords
alkyl
nhch
collagenase inhibitor
collagenase
cancer
Prior art date
Application number
HU9401420A
Other languages
English (en)
Other versions
HUT67374A (en
Inventor
Yukio Sugimura
Tomowo Kobayashi
Kazuhiko Tamaki
Kazuhiko Tanzawa
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of HU9401420D0 publication Critical patent/HU9401420D0/hu
Publication of HUT67374A publication Critical patent/HUT67374A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HU9401420A 1991-11-08 1992-11-02 Process for producing hexahydropyridazine carboxylic acid derivatives and pharmaceutical compositions containing them HUT67374A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP29288491 1991-11-08

Publications (2)

Publication Number Publication Date
HU9401420D0 true HU9401420D0 (en) 1994-08-29
HUT67374A HUT67374A (en) 1995-03-28

Family

ID=17787629

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9401420A HUT67374A (en) 1991-11-08 1992-11-02 Process for producing hexahydropyridazine carboxylic acid derivatives and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (1) US5643908A (hu)
EP (1) EP0621270B1 (hu)
JP (2) JPH05194414A (hu)
KR (1) KR100255203B1 (hu)
AT (1) ATE191713T1 (hu)
AU (1) AU661058B2 (hu)
CA (1) CA2123104A1 (hu)
CZ (1) CZ112694A3 (hu)
DE (1) DE69230916T2 (hu)
DK (1) DK0621270T3 (hu)
ES (1) ES2145014T3 (hu)
FI (1) FI942094A (hu)
GR (1) GR3033368T3 (hu)
HU (1) HUT67374A (hu)
NO (1) NO306507B1 (hu)
RU (1) RU2091373C1 (hu)
WO (1) WO1993009097A1 (hu)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9223904D0 (en) * 1992-11-13 1993-01-06 British Bio Technology Inhibition of cytokine production
DK0822186T3 (da) * 1994-01-20 2000-06-26 British Biotech Pharm L-tert-leucin-2-pyridylamid
WO1995029892A1 (en) * 1994-04-28 1995-11-09 The Du Pont Merck Pharmaceutical Company Hydroxamic acid and amino acid derivatives and their use as anti-arthritic agents
GB9411598D0 (en) * 1994-06-09 1994-08-03 Hoffmann La Roche Hydroxamic acid derivatives
GB9423914D0 (en) * 1994-11-26 1995-01-11 British Biotech Pharm Polyether derivatives as metalloproteinase inhibitors
US5919940A (en) * 1995-01-20 1999-07-06 British Biotech Pharmaceuticals Limited Metalloproteinase inhibitors
US5917090A (en) * 1995-06-30 1999-06-29 British Biotech Pharmaceuticals Ltd. Matrix metalloproteinase inhibitors
HUP9903863A3 (en) 1995-11-23 2000-11-28 British Biotech Pharm Metalloproteinase inhibitors
WO1997031901A1 (en) * 1996-02-29 1997-09-04 Mikael Bols Hydroxyhexahydropyridazines
US6462023B1 (en) 1996-09-10 2002-10-08 British Biotech Pharmaceuticals, Ltd. Cytostatic agents
US6953788B1 (en) 1996-09-19 2005-10-11 Aventis Pharmaceuticals Inc. 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase
GB9803005D0 (en) 1998-02-12 1998-04-08 British Biotech Pharm Anti-inflammatory agents
US6417189B1 (en) 1999-11-12 2002-07-09 Gpi Nil Holdings, Inc. AZA compounds, pharmaceutical compositions and methods of use
US7253169B2 (en) * 1999-11-12 2007-08-07 Gliamed, Inc. Aza compounds, pharmaceutical compositions and methods of use
US6797820B2 (en) 1999-12-17 2004-09-28 Vicuron Pharmaceuticals Inc. Succinate compounds, compositions and methods of use and preparation
WO2002102791A1 (en) 2001-06-15 2002-12-27 Vicuron Pharmaceuticals Inc. Pyrrolidine bicyclic compounds
AR036053A1 (es) 2001-06-15 2004-08-04 Versicor Inc Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas
US20030068655A1 (en) * 2001-09-12 2003-04-10 Protiveris, Inc. Microcantilever apparatus and methods for detection of enzymes
FR2835835B1 (fr) * 2002-02-11 2004-04-16 Aventis Pharma Sa Nouveaux derives de la pyridazine, leur utilisation comme medicaments, compositions pharmaceutiques et leur procede de preparation
US7807177B2 (en) 2004-01-27 2010-10-05 Toshikazu Nakamura Segment of glycosylation-deficient HGFalpha-chain
WO2009089235A1 (en) * 2008-01-07 2009-07-16 Janssen Pharmaceutica N.V. Preparation of sulfamide derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659711A (en) * 1983-01-31 1987-04-21 Usv Pharmaceutical Corporation 1,2,3,4-Tetrahydrophthalazine and hexahydropyridazine compounds for treating hypertension
US4604407A (en) * 1985-04-04 1986-08-05 E. R. Squibb & Sons, Inc. Hydroxamates
JPH0670019B2 (ja) * 1989-07-21 1994-09-07 明治製菓株式会社 新抗生物質ｓｆ２１９７ｃ物質およびその製造法
JPH03157372A (ja) * 1989-11-13 1991-07-05 Yamanouchi Pharmaceut Co Ltd Ｙｌ―０１８６９ｐ物質及びその製造法
WO1991017982A1 (en) * 1990-05-21 1991-11-28 Sankyo Company, Limited Novel compound matristatin
WO1992022523A2 (en) * 1991-06-14 1992-12-23 Research Corporation Technologies, Inc. Peptide derivatives of collagenase inhibitor

Also Published As

Publication number Publication date
JPH05194414A (ja) 1993-08-03
NO306507B1 (no) 1999-11-15
KR100255203B1 (ko) 2000-05-01
AU661058B2 (en) 1995-07-13
EP0621270A1 (en) 1994-10-26
FI942094A0 (fi) 1994-05-06
RU2091373C1 (ru) 1997-09-27
HUT67374A (en) 1995-03-28
US5643908A (en) 1997-07-01
AU2799392A (en) 1993-06-07
DK0621270T3 (da) 2000-07-17
GR3033368T3 (en) 2000-09-29
ATE191713T1 (de) 2000-04-15
EP0621270A4 (en) 1995-01-18
FI942094A (fi) 1994-07-01
ES2145014T3 (es) 2000-07-01
NO941698L (no) 1994-07-07
CZ112694A3 (en) 1994-12-15
WO1993009097A1 (en) 1993-05-13
CA2123104A1 (en) 1993-05-13
NO941698D0 (no) 1994-05-06
JPH05194415A (ja) 1993-08-03
DE69230916D1 (de) 2000-05-18
EP0621270B1 (en) 2000-04-12
DE69230916T2 (de) 2000-12-14

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Legal Events

Date Code Title Description
DFC4 Cancellation of temporary protection due to refusal