ATE268769T1 - Pyrimidinderivate mit antitumor-wirkung - Google Patents

Pyrimidinderivate mit antitumor-wirkung

Info

Publication number
ATE268769T1
ATE268769T1 AT01900628T AT01900628T ATE268769T1 AT E268769 T1 ATE268769 T1 AT E268769T1 AT 01900628 T AT01900628 T AT 01900628T AT 01900628 T AT01900628 T AT 01900628T AT E268769 T1 ATE268769 T1 AT E268769T1
Authority
AT
Austria
Prior art keywords
pyrimidine derivatives
tumor effect
alkyl
hydrogen atom
independently hydrogen
Prior art date
Application number
AT01900628T
Other languages
English (en)
Inventor
Hidekazu Tanaka
Fukushima-Ku
Kazuo Ueda
Shinji Suzuki
Hideyuki Takenaka
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Application granted granted Critical
Publication of ATE268769T1 publication Critical patent/ATE268769T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT01900628T 2000-01-14 2001-01-09 Pyrimidinderivate mit antitumor-wirkung ATE268769T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000005553 2000-01-14
PCT/JP2001/000036 WO2001051488A1 (en) 2000-01-14 2001-01-09 Pyrimidine derivatives having antitumor effect

Publications (1)

Publication Number Publication Date
ATE268769T1 true ATE268769T1 (de) 2004-06-15

Family

ID=18534207

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01900628T ATE268769T1 (de) 2000-01-14 2001-01-09 Pyrimidinderivate mit antitumor-wirkung

Country Status (10)

Country Link
US (1) US6800630B2 (de)
EP (1) EP1251129B1 (de)
KR (1) KR20020079779A (de)
CN (1) CN1416429A (de)
AT (1) ATE268769T1 (de)
AU (1) AU2001225466A1 (de)
CA (1) CA2396324A1 (de)
DE (1) DE60103732T2 (de)
ES (1) ES2222331T3 (de)
WO (1) WO2001051488A1 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0672041T3 (da) 1993-10-01 2002-02-25 Novartis Ag Farmakologisk aktive pyridinderivater og fremgangsmåder til fremstilling deraf
US5608067A (en) 1993-12-09 1997-03-04 Afonso; Adriano 4-substituted pyrazoloquinoline derivatives
US5439918A (en) * 1994-03-14 1995-08-08 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
CA2336832A1 (en) * 1998-07-16 2000-01-27 Shionogi & Co., Ltd. Pyrimidine derivatives exhibiting antitumor activity

Also Published As

Publication number Publication date
WO2001051488A1 (en) 2001-07-19
KR20020079779A (ko) 2002-10-19
EP1251129B1 (de) 2004-06-09
CA2396324A1 (en) 2001-07-19
EP1251129A4 (de) 2003-03-05
AU2001225466A1 (en) 2001-07-24
DE60103732T2 (de) 2005-06-30
DE60103732D1 (de) 2004-07-15
EP1251129A1 (de) 2002-10-23
ES2222331T3 (es) 2005-02-01
US6800630B2 (en) 2004-10-05
US20030203894A1 (en) 2003-10-30
CN1416429A (zh) 2003-05-07

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties