HU9202047D0 - Method for producing n-phenyl-thiourea derivatives and pharmaceutical prepartives containing these compounds as active agents - Google Patents

Method for producing n-phenyl-thiourea derivatives and pharmaceutical prepartives containing these compounds as active agents

Info

Publication number
HU9202047D0
HU9202047D0 HU9202047A HU9202047A HU9202047D0 HU 9202047 D0 HU9202047 D0 HU 9202047D0 HU 9202047 A HU9202047 A HU 9202047A HU 9202047 A HU9202047 A HU 9202047A HU 9202047 D0 HU9202047 D0 HU 9202047D0
Authority
HU
Hungary
Prior art keywords
compounds
prepartives
phenyl
pharmaceutical
producing
Prior art date
Application number
HU9202047A
Other languages
English (en)
Other versions
HUT62558A (en
Inventor
Gary Mark Coppola
Robert Edson Damon
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of HU9202047D0 publication Critical patent/HU9202047D0/hu
Publication of HUT62558A publication Critical patent/HUT62558A/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
HU9202047A 1991-07-01 1992-06-18 Process for producing n-phenylthiourea derivaties and pharmaceutical compositions comprising same HUT62558A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72400191A 1991-07-01 1991-07-01

Publications (2)

Publication Number Publication Date
HU9202047D0 true HU9202047D0 (en) 1992-09-28
HUT62558A HUT62558A (en) 1993-05-28

Family

ID=24908548

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9202047A HUT62558A (en) 1991-07-01 1992-06-18 Process for producing n-phenylthiourea derivaties and pharmaceutical compositions comprising same

Country Status (24)

Country Link
EP (1) EP0528146B1 (hu)
JP (1) JPH05221959A (hu)
KR (1) KR930002311A (hu)
AT (1) ATE134364T1 (hu)
AU (1) AU657141B2 (hu)
CA (1) CA2072704A1 (hu)
CZ (1) CZ204692A3 (hu)
DE (1) DE69208408T2 (hu)
DK (1) DK0528146T3 (hu)
ES (1) ES2083625T3 (hu)
FI (1) FI923033A (hu)
GR (1) GR3019785T3 (hu)
HK (1) HK73196A (hu)
HU (1) HUT62558A (hu)
IE (1) IE73488B1 (hu)
IL (1) IL102355A0 (hu)
MX (1) MX9203838A (hu)
NO (1) NO922564L (hu)
NZ (1) NZ243352A (hu)
RO (1) RO111933B1 (hu)
RU (1) RU2087467C1 (hu)
SK (1) SK204692A3 (hu)
TW (1) TW213448B (hu)
ZA (1) ZA924823B (hu)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998021190A1 (en) * 1996-11-14 1998-05-22 American Home Products Corporation Substituted tetrahydro-1,3,5-triazin-2[1h]-thiones as anti-atherosclerotic agents
WO1998033775A1 (en) * 1997-02-03 1998-08-06 American Home Products Corporation 2-substituted-1-acyl-1,2-dihydroquinoline derivatives to increase hdl-cholesterol level
AU7498298A (en) * 1997-06-16 1999-01-04 American Home Products Corporation Elevation of hdl cholesterol by n-{2-{ (aminothioxomethyl)hydrazono} -2-arylethyl}amides
US6011053A (en) * 1997-08-01 2000-01-04 American Home Products Corporation Substituted indole-1-carbothioic acid amides as novel antiatherosclerotic agents
AU9125998A (en) * 1997-09-03 1999-03-22 American Home Products Corporation Substituted indole-1-carbothioic acid amides as novel antiatherosclerotic agents
TW415942B (en) * 1997-09-03 2000-12-21 American Home Prod Novel substituted 1-aryl-3-heteroaryl-thioureas and substituted 1-aryl-3-heteroaryl-isothioureas as antiatherosclerotic agents
US6455566B1 (en) 1997-09-03 2002-09-24 Wyeth Substituted 1-aryl-3-heteroaryl-thioureas (or isothioureas) as antiatherosclerotic agents
AU9211098A (en) * 1997-09-03 1999-03-22 American Home Products Corporation Thiourea for increasing hdl-cholesterol levels, which are useful as anti-atherosclerotic agents
DE10017881A1 (de) * 2000-04-11 2001-10-25 Bayer Ag Wirkstoffkombinationen mit insektiziden und akariziden Eigenschaften
WO2003024441A1 (fr) 2001-09-14 2003-03-27 Shionogi & Co., Ltd. Nouvelle utilisation de composes tricycliques
JP2004506714A (ja) 2000-08-21 2004-03-04 パシフィック　コーポレーション 新規チオ尿素化合物及びこれを含有する薬学的組成物
ATE393141T1 (de) 2000-08-21 2008-05-15 Pacific Corp Neue thiourea-derivate und pharmazeutische zusammensetzungen die diese enthalten
US6472430B2 (en) 2000-10-02 2002-10-29 Hassan M. Elokdah Amino thioxomethyl amino oxyacetic acid derivatives
US7429593B2 (en) 2001-09-14 2008-09-30 Shionogi & Co., Ltd. Utilities of amide compounds
US8124625B2 (en) 2001-09-14 2012-02-28 Shionogi & Co., Ltd. Method of enhancing the expression of apolipoprotein AI using olefin derivatives
ES2362770B1 (es) * 2009-12-24 2012-05-22 Universidad De Sevilla Uso de compuesto n-fenil-n'-(3-metil-2-butenil)tiourea para la elaboración de medicamentos destinados al tratamiento de la encefalopatía hepática.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950537A (en) * 1973-06-29 1976-04-13 Rohm And Haas Company Gastrointestinally active thioureas
IL67417A (en) * 1982-01-26 1989-10-31 American Cyanamid Co Antiatherosclerotic substituted ureas,process for their preparation and pharmaceutical compositions containing them
ATE61574T1 (de) * 1987-07-02 1991-03-15 Warner Lambert Co N-((2,6-disubstituierte)-phenyl>-harnstoff und - carbamat-inhibitoren der acyl-coenzym a:cholesterol-acyltransferase.
US5116848A (en) * 1988-03-30 1992-05-26 Warner-Lambert Company N-(((2,6-disubstituted)phenyl)-n-diarylalkyl)ureas as antihyperlipidemic and antiatherosclerotic agents
GB8908063D0 (en) * 1989-04-11 1989-05-24 Beecham Group Plc Novel compounds
JPH0395153A (ja) * 1989-06-15 1991-04-19 Mitsubishi Kasei Corp ジフェニル尿素誘導体

Also Published As

Publication number Publication date
HUT62558A (en) 1993-05-28
RU2087467C1 (ru) 1997-08-20
IL102355A0 (en) 1993-01-14
AU657141B2 (en) 1995-03-02
CA2072704A1 (en) 1993-01-02
MX9203838A (es) 1993-01-01
FI923033A0 (fi) 1992-06-30
KR930002311A (ko) 1993-02-22
IE73488B1 (en) 1997-06-04
CZ204692A3 (en) 1993-01-13
JPH05221959A (ja) 1993-08-31
ES2083625T3 (es) 1996-04-16
ZA924823B (en) 1993-12-29
DK0528146T3 (da) 1996-05-06
SK204692A3 (en) 1995-02-08
IE922132A1 (en) 1993-01-13
NO922564D0 (no) 1992-06-29
AU1867792A (en) 1993-01-07
RO111933B1 (ro) 1997-03-31
DE69208408T2 (de) 1996-07-18
EP0528146A1 (en) 1993-02-24
FI923033A (fi) 1993-01-02
DE69208408D1 (de) 1996-03-28
TW213448B (hu) 1993-09-21
GR3019785T3 (en) 1996-07-31
EP0528146B1 (en) 1996-02-21
NO922564L (no) 1993-01-04
HK73196A (en) 1996-05-03
NZ243352A (en) 1995-02-24
ATE134364T1 (de) 1996-03-15

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Legal Events

Date Code Title Description
DFA9 Temporary protection cancelled due to abandonment