HU208636B - Process for producing pharmaceutical compositions neutralizing procoagulant activity caused by tumour cells - Google Patents

Process for producing pharmaceutical compositions neutralizing procoagulant activity caused by tumour cells Download PDF

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Publication number
HU208636B
HU208636B HU9201552A HU155292A HU208636B HU 208636 B HU208636 B HU 208636B HU 9201552 A HU9201552 A HU 9201552A HU 155292 A HU155292 A HU 155292A HU 208636 B HU208636 B HU 208636B
Authority
HU
Hungary
Prior art keywords
leu
glu
asp
lys
thr
Prior art date
Application number
HU9201552A
Other languages
English (en)
Hungarian (hu)
Other versions
HUT61202A (en
HU9201552D0 (en
Inventor
Christiaan Reutelingsperger
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of HU9201552D0 publication Critical patent/HU9201552D0/hu
Publication of HUT61202A publication Critical patent/HUT61202A/hu
Publication of HU208636B publication Critical patent/HU208636B/hu

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
HU9201552A 1989-11-11 1990-11-08 Process for producing pharmaceutical compositions neutralizing procoagulant activity caused by tumour cells HU208636B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3937607A DE3937607A1 (de) 1989-11-11 1989-11-11 Verwendung eines antikoagulanz zur behandlung von tumorerkrankungen

Publications (3)

Publication Number Publication Date
HU9201552D0 HU9201552D0 (en) 1992-08-28
HUT61202A HUT61202A (en) 1992-12-28
HU208636B true HU208636B (en) 1993-12-28

Family

ID=6393365

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9201552A HU208636B (en) 1989-11-11 1990-11-08 Process for producing pharmaceutical compositions neutralizing procoagulant activity caused by tumour cells

Country Status (9)

Country Link
EP (1) EP0500602B1 (fr)
JP (1) JPH05501876A (fr)
AT (1) ATE120371T1 (fr)
CA (1) CA2068312A1 (fr)
DE (2) DE3937607A1 (fr)
DK (1) DK0500602T3 (fr)
ES (1) ES2071833T3 (fr)
HU (1) HU208636B (fr)
WO (1) WO1991007187A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968477A (en) 1994-01-24 1999-10-19 Neorx Corporation Radiolabeled annexin conjugates with hexose and a chelator
CA2180555C (fr) * 1994-01-24 2004-12-14 Sudhakar Kasina Annexines marquees isotopiquement
US20030220233A1 (en) 1994-01-24 2003-11-27 Neorx Corporation Radiolabeled annexins
WO1995034315A1 (fr) * 1994-06-16 1995-12-21 Neorx Corporation Conjugues radiomarques d'annexine-galactose
EP0799050B1 (fr) * 1994-12-07 2004-08-11 Neorx Corporation Conjugues groupes annexine-galactose radiomarques
JPH10512852A (ja) * 1994-12-07 1998-12-08 ネオルクス コーポレイション 放射性標識化アネキシン−ガラクトースクラスター複合体
US6509316B2 (en) 1995-03-07 2003-01-21 George Washington University Pharmaceutical compositions, methods, and kits for treatment and diagnosis of lung cancer
US6288039B1 (en) 1995-03-07 2001-09-11 George Washington University Pharmaceutical compositions methods and kits for treatment and diagnosis of breast cancer
US5935860A (en) 1995-03-07 1999-08-10 The George Washington University Use of uteroglobin expression as a molecular marker for prostatic intraepithelial neoplasia
US5696092A (en) * 1995-03-07 1997-12-09 George Washington University Methods and compositions for inhibiting metastasis of epithelial cell-derived cancers
ATE230614T1 (de) 1998-07-13 2003-01-15 Univ Texas Krebsbehandlung mit aminophospholipide bindenden, therapeutischen konjugaten
AU2004202605B2 (en) 1998-07-13 2007-10-25 Board Of Regents, The University Of Texas System Cancer treatment methods using antibodies to aminophospholipids
US6406693B1 (en) 1998-07-13 2002-06-18 Board Of Regents, The University Of Texas System Cancer treatment methods using antibodies to aminophospholipids
EP1520588B1 (fr) 1998-07-13 2014-12-24 Board Of Regents, The University Of Texas System L'utilisation d'anticorps vis-a-vis des aminophospholipides pour le traitement du cancer
US6818213B1 (en) 1998-07-13 2004-11-16 Board Of Regents, The University Of Texas System Cancer treatment compositions comprising therapeutic conjugates that bind to aminophospholipids
US7645739B2 (en) 2001-02-21 2010-01-12 Alavita Pharmaceuticals, Inc. Modified annexin compositions and methods of using same
US7635676B2 (en) 2001-02-21 2009-12-22 Alavita Pharmaccuticals, Inc. Modified annexin proteins and methods for their use in organ transplantation
EP1839670A3 (fr) 2001-02-21 2009-11-11 Alavita Pharmaceuticals, Inc. Protéines d'annexine modifiées et leur utilisation contre la thrombose
US7635680B2 (en) 2001-02-21 2009-12-22 Alavita Pharmaceuticals, Inc. Attenuation of reperfusion injury

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT87083B (pt) * 1987-03-28 1992-07-31 Boehringer Ingelheim Int Processo para a preparacao de uma proteina anticoagulante vascular, de adn que codifica para esta proteina e de composicoes farmaceuticas que a contem

Also Published As

Publication number Publication date
DE59008813D1 (de) 1995-05-04
WO1991007187A1 (fr) 1991-05-30
HUT61202A (en) 1992-12-28
DE3937607A1 (de) 1991-05-16
JPH05501876A (ja) 1993-04-08
ATE120371T1 (de) 1995-04-15
EP0500602A1 (fr) 1992-09-02
ES2071833T3 (es) 1995-07-01
CA2068312A1 (fr) 1991-05-12
HU9201552D0 (en) 1992-08-28
EP0500602B1 (fr) 1995-03-29
DK0500602T3 (da) 1995-07-10

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee