DK0500602T3 - Middel til neutralisering af til tumorceller knyttet prokoagulantaktivitet - Google Patents

Middel til neutralisering af til tumorceller knyttet prokoagulantaktivitet

Info

Publication number
DK0500602T3
DK0500602T3 DK90916090.5T DK90916090T DK0500602T3 DK 0500602 T3 DK0500602 T3 DK 0500602T3 DK 90916090 T DK90916090 T DK 90916090T DK 0500602 T3 DK0500602 T3 DK 0500602T3
Authority
DK
Denmark
Prior art keywords
agent
neutralizing
tumor cells
activity associated
procoagulant activity
Prior art date
Application number
DK90916090.5T
Other languages
English (en)
Inventor
Christiaan Reutelingsperger
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Application granted granted Critical
Publication of DK0500602T3 publication Critical patent/DK0500602T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
DK90916090.5T 1989-11-11 1990-11-08 Middel til neutralisering af til tumorceller knyttet prokoagulantaktivitet DK0500602T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3937607A DE3937607A1 (de) 1989-11-11 1989-11-11 Verwendung eines antikoagulanz zur behandlung von tumorerkrankungen

Publications (1)

Publication Number Publication Date
DK0500602T3 true DK0500602T3 (da) 1995-07-10

Family

ID=6393365

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90916090.5T DK0500602T3 (da) 1989-11-11 1990-11-08 Middel til neutralisering af til tumorceller knyttet prokoagulantaktivitet

Country Status (9)

Country Link
EP (1) EP0500602B1 (da)
JP (1) JPH05501876A (da)
AT (1) ATE120371T1 (da)
CA (1) CA2068312A1 (da)
DE (2) DE3937607A1 (da)
DK (1) DK0500602T3 (da)
ES (1) ES2071833T3 (da)
HU (1) HU208636B (da)
WO (1) WO1991007187A1 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030220233A1 (en) 1994-01-24 2003-11-27 Neorx Corporation Radiolabeled annexins
WO1995019791A1 (en) * 1994-01-24 1995-07-27 Neorx Corporation Radiolabeled annexins
US5968477A (en) * 1994-01-24 1999-10-19 Neorx Corporation Radiolabeled annexin conjugates with hexose and a chelator
JPH10504534A (ja) * 1994-06-16 1998-05-06 ネオルクス コーポレイション 放射性標識アネキシン−ガラクトース結合体
CA2206274C (en) * 1994-12-07 2009-06-30 Neorx Corporation Radiolabeled annexin-galactose cluster conjugates
JPH10512852A (ja) * 1994-12-07 1998-12-08 ネオルクス コーポレイション 放射性標識化アネキシン−ガラクトースクラスター複合体
US5935860A (en) 1995-03-07 1999-08-10 The George Washington University Use of uteroglobin expression as a molecular marker for prostatic intraepithelial neoplasia
US6509316B2 (en) 1995-03-07 2003-01-21 George Washington University Pharmaceutical compositions, methods, and kits for treatment and diagnosis of lung cancer
US6288039B1 (en) 1995-03-07 2001-09-11 George Washington University Pharmaceutical compositions methods and kits for treatment and diagnosis of breast cancer
US5696092A (en) * 1995-03-07 1997-12-09 George Washington University Methods and compositions for inhibiting metastasis of epithelial cell-derived cancers
JP2002520297A (ja) 1998-07-13 2002-07-09 ボード オブ リージェンツ， ザ ユニバーシティ オブ テキサス システム アミノリン脂質に結合する治療結合体を用いる癌処置方法
EP1520588B1 (en) 1998-07-13 2014-12-24 Board Of Regents, The University Of Texas System Uses of antibodies to aminophospholipids for cancer treatment
US6818213B1 (en) 1998-07-13 2004-11-16 Board Of Regents, The University Of Texas System Cancer treatment compositions comprising therapeutic conjugates that bind to aminophospholipids
US6406693B1 (en) 1998-07-13 2002-06-18 Board Of Regents, The University Of Texas System Cancer treatment methods using antibodies to aminophospholipids
CA2333147C (en) 1998-07-13 2012-02-07 Board Of Regents, The University Of Texas System Cancer treatment methods using antibodies to aminophospholipids
US7635676B2 (en) 2001-02-21 2009-12-22 Alavita Pharmaccuticals, Inc. Modified annexin proteins and methods for their use in organ transplantation
US7645739B2 (en) 2001-02-21 2010-01-12 Alavita Pharmaceuticals, Inc. Modified annexin compositions and methods of using same
EP1839670A3 (en) 2001-02-21 2009-11-11 Alavita Pharmaceuticals, Inc. Modified Annexin Proteins and their use against thrombosis
US7635680B2 (en) 2001-02-21 2009-12-22 Alavita Pharmaceuticals, Inc. Attenuation of reperfusion injury

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT87083B (pt) * 1987-03-28 1992-07-31 Boehringer Ingelheim Int Processo para a preparacao de uma proteina anticoagulante vascular, de adn que codifica para esta proteina e de composicoes farmaceuticas que a contem

Also Published As

Publication number Publication date
EP0500602B1 (de) 1995-03-29
JPH05501876A (ja) 1993-04-08
HU208636B (en) 1993-12-28
HU9201552D0 (en) 1992-08-28
ATE120371T1 (de) 1995-04-15
CA2068312A1 (en) 1991-05-12
DE59008813D1 (de) 1995-05-04
WO1991007187A1 (de) 1991-05-30
DE3937607A1 (de) 1991-05-16
ES2071833T3 (es) 1995-07-01
HUT61202A (en) 1992-12-28
EP0500602A1 (de) 1992-09-02

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