HU184704B - Process for preparing biologically active encephaline analogues - Google Patents

Process for preparing biologically active encephaline analogues Download PDF

Info

Publication number
HU184704B
HU184704B HU77WE548A HUWE000548A HU184704B HU 184704 B HU184704 B HU 184704B HU 77WE548 A HU77WE548 A HU 77WE548A HU WE000548 A HUWE000548 A HU WE000548A HU 184704 B HU184704 B HU 184704B
Authority
HU
Hungary
Prior art keywords
formula
gly
phe
tyr
compound
Prior art date
Application number
HU77WE548A
Other languages
English (en)
Hungarian (hu)
Inventor
Samuel Wilkinson
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB2900/76A external-priority patent/GB1577114A/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of HU184704B publication Critical patent/HU184704B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70—Enkephalins
    • C07K14/702—Enkephalins with at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
HU77WE548A 1976-01-26 1977-01-26 Process for preparing biologically active encephaline analogues HU184704B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2900/76A GB1577114A (en) 1976-01-26 1976-01-26 Biologically active peptides
GB848176 1976-03-03
GB4882176 1976-11-23

Publications (1)

Publication Number Publication Date
HU184704B true HU184704B (en) 1984-10-29

Family

ID=27254145

Family Applications (1)

Application Number Title Priority Date Filing Date
HU77WE548A HU184704B (en) 1976-01-26 1977-01-26 Process for preparing biologically active encephaline analogues

Country Status (11)

Country Link
JP (1) JPS5291839A (es)
CH (1) CH644352A5 (es)
DE (1) DE2703109A1 (es)
DK (1) DK33177A (es)
ES (1) ES455365A1 (es)
FI (1) FI70228C (es)
FR (1) FR2338925A1 (es)
HU (1) HU184704B (es)
IL (1) IL51332A (es)
NL (1) NL7700785A (es)
SE (1) SE7708404L (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4003000A (en) * 1975-05-27 1977-01-11 Sperry Rand Corporation Sinusoidal oscillator with electronically variable frequency
US4261888A (en) * 1976-04-12 1981-04-14 Sandoz Ltd. Organic compounds
FR2359817A1 (fr) * 1976-07-27 1978-02-24 Reckitt & Colmann Prod Ltd Nouveaux peptides, leur procede de preparation et composition therapeutique les contenant
GB1532148A (en) * 1976-08-09 1978-11-15 Searle & Co 1-substituted enkepholin derivatives
HU178001B (en) * 1976-09-16 1982-02-28 Gyogyszekutato Intezet Process for preparing new pentapeptides with morphine-like activity and derivatives thereof
DE2819277A1 (de) * 1977-05-16 1978-11-23 Sandoz Ag Neue polypeptidderivate, ihre herstellung und verwendung
GB2000784B (en) * 1977-07-05 1982-01-20 American Home Prod Analgesic polypetide
EP0000559B1 (en) * 1977-07-22 1983-10-05 The Wellcome Foundation Limited Pentapeptide-n-alkylamides and their acid addition salts, methods for preparation of these compounds and pharmaceutical formulations containing them
US4264491A (en) * 1977-10-03 1981-04-28 Eli Lilly And Company Analgesic compounds
HU182051B (en) * 1978-05-02 1983-12-28 Takeda Chemical Industries Ltd Process for preparing tetrapeptide-hydrazyde derivatives
US4278596A (en) * 1978-08-08 1981-07-14 American Home Products Corporation Analgesic pentapeptides
CA1175810A (en) * 1979-03-30 1984-10-09 Frank A. Momany Synthetic peptides having pituitary growth hormone releasing activity
US4247543A (en) * 1979-04-09 1981-01-27 Sandoz Ltd. Organic compounds
US4396606A (en) * 1979-11-05 1983-08-02 Addiction Research Foundation Novel polypeptide analgesics
DE3163199D1 (en) * 1980-07-17 1984-05-24 Sandoz Ag Novel pentapeptides, processes for their production, pharmaceutical compositions comprising said pentapeptides and their use
FR2488253A1 (fr) * 1980-08-08 1982-02-12 Roques Bernard Nouveaux peptides et leur application en therapeutique
JPS58501861A (ja) * 1981-12-28 1983-11-04 ベツクマン・インストルメンツ・インコ−ポレ−テツド 下垂体成長ホルモン放出活性を有する合成ペプチド
US4491541A (en) * 1982-11-10 1985-01-01 Farmitalia Carlo Erba Peptides
JPH0680079B2 (ja) * 1984-11-09 1994-10-12 エーザイ株式会社 ポリペプチド
AU618029B2 (en) * 1987-11-02 1991-12-12 Imperial Chemical Industries Plc Polypeptide compounds
WO1994011018A1 (en) * 1992-11-12 1994-05-26 Biomeasure, Inc. Opioid peptides
KR101351775B1 (ko) * 2009-04-13 2014-01-14 이엘씨 매니지먼트 엘엘씨 메티오닌 술폭시드 펩티드, 조성물 및 사용 방법
EP4092038A1 (en) 2017-09-11 2022-11-23 Protagonist Therapeutics, Inc. Opioid agonist peptides and uses thereof

Also Published As

Publication number Publication date
NL7700785A (nl) 1977-07-28
FI770254A (es) 1977-07-27
JPS5291839A (en) 1977-08-02
CH644352A5 (en) 1984-07-31
ES455365A1 (es) 1978-05-16
DK33177A (da) 1977-07-27
FI70228C (fi) 1986-09-15
IL51332A0 (en) 1977-03-31
FR2338925A1 (fr) 1977-08-19
IL51332A (en) 1980-09-16
DE2703109A1 (de) 1977-08-04
FR2338925B1 (es) 1980-08-08
FI70228B (fi) 1986-02-28
SE7708404L (sv) 1977-07-27

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