HU179344B - Process for producing andorstan-17-one derivatives - Google Patents

Process for producing andorstan-17-one derivatives

Info

Publication number
HU179344B
HU179344B HU77SCHE614A HUSC000614A HU179344B HU 179344 B HU179344 B HU 179344B HU 77SCHE614 A HU77SCHE614 A HU 77SCHE614A HU SC000614 A HUSC000614 A HU SC000614A HU 179344 B HU179344 B HU 179344B
Authority
HU
Hungary
Prior art keywords
andorstan
derivatives
producing
producing andorstan
Prior art date
Application number
HU77SCHE614A
Other languages
English (en)
Hungarian (hu)
Inventor
Alfred Weber
Mario Kennecke
Helmut Dahl
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of HU179344B publication Critical patent/HU179344B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/005—Degradation of the lateral chains at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0048—Alkynyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/863—Mycobacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU77SCHE614A 1976-07-16 1977-07-15 Process for producing andorstan-17-one derivatives HU179344B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762632677 DE2632677A1 (de) 1976-07-16 1976-07-16 Verfahren zur herstellung von androstan-17-on-derivaten und deren verwendung

Publications (1)

Publication Number Publication Date
HU179344B true HU179344B (en) 1982-10-28

Family

ID=5983514

Family Applications (4)

Application Number Title Priority Date Filing Date
HU77SCHE614A HU179344B (en) 1976-07-16 1977-07-15 Process for producing andorstan-17-one derivatives
HU8019A HU182790B (en) 1976-07-16 1977-07-15 Process for preparing 17beta-hydroxy-5-androstene derivatives
HU8018A HU182789B (en) 1976-07-16 1977-07-15 Process for producing 3-beta-hydroxy-5-androsten-17-one
HU8020A HU182681B (en) 1976-07-16 1977-07-15 Process for preparing androstane derivatives

Family Applications After (3)

Application Number Title Priority Date Filing Date
HU8019A HU182790B (en) 1976-07-16 1977-07-15 Process for preparing 17beta-hydroxy-5-androstene derivatives
HU8018A HU182789B (en) 1976-07-16 1977-07-15 Process for producing 3-beta-hydroxy-5-androsten-17-one
HU8020A HU182681B (en) 1976-07-16 1977-07-15 Process for preparing androstane derivatives

Country Status (18)

Country Link
US (1) US4179336A (OSRAM)
JP (1) JPS5315493A (OSRAM)
AT (1) AT363196B (OSRAM)
BE (1) BE856860A (OSRAM)
CH (3) CH627190A5 (OSRAM)
CS (1) CS200517B2 (OSRAM)
DD (4) DD136141A5 (OSRAM)
DE (1) DE2632677A1 (OSRAM)
DK (1) DK142372C (OSRAM)
FR (4) FR2365588A1 (OSRAM)
GB (1) GB1585786A (OSRAM)
HU (4) HU179344B (OSRAM)
IE (1) IE45304B1 (OSRAM)
IT (1) IT1077339B (OSRAM)
NL (1) NL7706638A (OSRAM)
SE (1) SE440779B (OSRAM)
SU (1) SU980628A3 (OSRAM)
YU (1) YU164277A (OSRAM)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55148083A (en) * 1979-05-04 1980-11-18 Mitsubishi Chem Ind Ltd Microorganism
JPS55150893A (en) * 1979-05-11 1980-11-25 Mitsubishi Chem Ind Ltd Novel microorganism
JPS578794A (en) * 1980-06-17 1982-01-18 Mitsubishi Chem Ind Ltd Preparation of androstane-type steroid
US4444884A (en) * 1982-05-25 1984-04-24 Wisconsin Alumni Research Foundation Process for preparing steroids
US4755463A (en) * 1982-05-25 1988-07-05 Wisconsin Alumni Research Foundation Process for preparing steroids
DE69621281T2 (de) * 1995-02-28 2002-12-05 Nippon Shokubai Co., Ltd. Acryl-Säure-Derivate, Verfahren zur Herstellung von Acryl-Säure-Derivaten und Acryl-Säure-Polymere
PT2644206T (pt) * 2003-05-23 2019-07-10 Nektar Therapeutics Derivados de peg contendo duas cadeias de peg
KR101293278B1 (ko) * 2009-10-29 2013-08-09 주식회사 한독 신규 혈관누출 차단제
US9388210B2 (en) 2011-02-25 2016-07-12 Washington University Neuroactive 17(20)-Z-vinylcyano-substituted steroids, prodrugs thereof, and methods of treatment using same
CN104136452A (zh) 2011-10-14 2014-11-05 萨奇治疗股份有限公司 3,3-二取代的19-去甲孕甾烷化合物、组合物、及其用途
RS57390B1 (sr) 2012-12-18 2018-09-28 Univ Washington Neuroaktivni 19-alkoksi-17-supstituisani steroidi, primenjivi u postupcima lečenja
EP2956466A4 (en) 2013-02-15 2016-11-02 Univ Washington NEUROACTIVE ENANTIOMERS 15, 16 AND 17 SUBSTITUTED STEROIDS AS MODULATORS FOR GABA-A RECEPTORS
US9512170B2 (en) 2013-03-01 2016-12-06 Washington University Neuroactive 13, 17-substituted steroids as modulators for GABA type-A receptors
US9365502B2 (en) 2013-03-11 2016-06-14 Washington University Neuroactive substituted cyclopenta[b]phenanthrenes as modulators for GABA type-A receptors
US9562026B2 (en) 2013-03-14 2017-02-07 Washington University Neuroactive substituted cyclopent[a]anthracenes as modulators for GABA type-A receptors
EP2986623B1 (en) 2013-04-17 2018-11-07 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-n-pyrazolyl steroids and methods of use thereof
SI2986624T1 (sl) 2013-04-17 2020-10-30 Sage Therapeutics, Inc. 19-nor nevroaktivni steroidi za metode zdravljenja
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
US9725481B2 (en) 2013-04-17 2017-08-08 Sage Therapeutics, Inc. 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
SI3021852T1 (sl) 2013-07-19 2021-07-30 Sage Therapeutics, Inc. Nevroaktivni steroidi, sestavki in uporabe le-teh
JP6466942B2 (ja) 2013-08-23 2019-02-06 セージ セラピューティクス， インコーポレイテッド 向神経活性ステロイド、組成物、及びその使用
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
EP4527461A3 (en) 2014-10-16 2025-06-25 Sage Therapeutics, Inc. A compound, compositions thereof and this compound for use in methods of treating cns disorders
RS60642B1 (sr) 2014-10-16 2020-09-30 Sage Therapeutics Inc Kompozicije i postupci za lečenje poremećaja cns-a
SMT202000276T1 (it) 2014-11-27 2020-07-08 Sage Therapeutics Inc Composizioni e metodi per trattare disturbi del snc
SMT202100113T1 (it) 2015-01-26 2021-05-07 Sage Therapeutics Inc Composizioni e metodi per trattare disturbi del snc
JP6875996B2 (ja) 2015-02-20 2021-05-26 セージ セラピューティクス， インコーポレイテッド 神経刺激性ステロイド、組成物、およびその使用
NZ790187A (en) 2016-07-11 2025-08-29 Sage Therapeutics Inc C7, C12, and C16 substituted neuroactive steroids and their methods of use
IL264129B2 (en) 2016-07-11 2024-05-01 Sage Therapeutics Inc C17, c20, and c21 substituted neuroactive steroids and their methods of use
SG11202112391UA (en) 2019-05-31 2021-12-30 Sage Therapeutics Inc Neuroactive steroids and compositions thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3451892A (en) * 1965-10-19 1969-06-24 Schering Corp Process for the preparation of steroidal compounds
NL6705450A (OSRAM) * 1965-10-22 1968-10-21
US3684657A (en) * 1970-05-11 1972-08-15 Searle & Co Selective microbiological degradation of steroidal 17-alkyls
US3759791A (en) * 1970-12-10 1973-09-18 Searle & Co Selective microbiological preparation of androst-4-ene-3,17-dione
US3738983A (en) * 1971-08-06 1973-06-12 Searle & Co Process for the preparation of 3-(3beta,17beta-dihydroxyandrost-5-en-17alpha-yl) propionic acid gamma-lactone
DE2534911C2 (de) * 1975-08-01 1985-04-18 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von 5-Androsten-17-on-Derivaten

Also Published As

Publication number Publication date
CH629222A5 (de) 1982-04-15
AT363196B (de) 1981-07-10
DD137235A5 (de) 1979-08-22
HU182789B (en) 1984-03-28
DK323677A (da) 1978-01-17
NL7706638A (nl) 1978-01-18
GB1585786A (en) 1981-03-11
HU182790B (en) 1984-03-28
CH627190A5 (OSRAM) 1981-12-31
FR2372176A1 (fr) 1978-06-23
IE45304L (en) 1978-01-16
DK142372B (da) 1980-10-20
SE7708192L (sv) 1978-01-17
SE440779B (sv) 1985-08-19
DE2632677A1 (de) 1978-01-26
DK142372C (da) 1981-03-23
JPS6117477B2 (OSRAM) 1986-05-07
HU182681B (en) 1984-02-28
FR2365588A1 (fr) 1978-04-21
DD132439A5 (de) 1978-09-27
YU164277A (en) 1982-08-31
DE2632677C2 (OSRAM) 1988-06-16
FR2372175A1 (fr) 1978-06-23
FR2372174A1 (fr) 1978-06-23
US4179336A (en) 1979-12-18
JPS5315493A (en) 1978-02-13
FR2365588B1 (OSRAM) 1982-06-25
ATA504677A (de) 1980-12-15
SU980628A3 (ru) 1982-12-07
CS200517B2 (en) 1980-09-15
DD136141A5 (de) 1979-06-20
BE856860A (fr) 1978-01-16
CH629503A5 (de) 1982-04-30
IT1077339B (it) 1985-05-04
IE45304B1 (en) 1982-07-28
DD136142A5 (de) 1979-06-20

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee
HRH9 Withdrawal of annulment decision
HMM4 Cancellation of final prot. due to non-payment of fee