HRPK20010470B1 - The utilisation of inhibitors of the sodium hydrogen exchanger for producing a medicament for preventing organ dysfunctions and diseases related to a particular age and for prolonging life - Google Patents

The utilisation of inhibitors of the sodium hydrogen exchanger for producing a medicament for preventing organ dysfunctions and diseases related to a particular age and for prolonging life

Info

Publication number
HRPK20010470B1
HRPK20010470B1 HR20010470A HRP20010470A HRPK20010470B1 HR PK20010470 B1 HRPK20010470 B1 HR PK20010470B1 HR 20010470 A HR20010470 A HR 20010470A HR P20010470 A HRP20010470 A HR P20010470A HR PK20010470 B1 HRPK20010470 B1 HR PK20010470B1
Authority
HR
Croatia
Prior art keywords
utilisation
medicament
inhibitors
producing
sodium hydrogen
Prior art date
Application number
HR20010470A
Other languages
English (en)
Inventor
Wolfgang Linz
Hans Jochen Lang
Bela Kelety
Peter Schmid
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of HRP20010470A2 publication Critical patent/HRP20010470A2/hr
Publication of HRPK20010470B1 publication Critical patent/HRPK20010470B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
HR20010470A 1998-12-23 2001-06-20 The utilisation of inhibitors of the sodium hydrogen exchanger for producing a medicament for preventing organ dysfunctions and diseases related to a particular age and for prolonging life HRPK20010470B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19859727A DE19859727A1 (de) 1998-12-23 1998-12-23 Die Verwendung von Hemmern des Natrium-Wasserstoff-Austauschers zur Herstellung eines Medikaments zur Verhinderung von altersbedingten Organ-Dysfunktionen, altersbedingten Erkrankungen zur Lebensverlängerung
PCT/EP1999/009621 WO2000038661A2 (de) 1998-12-23 1999-12-08 Die verwendung von hemmern des natrium-wasserstoff-austauschers zur herstellung eines medikaments zur verhinderung von altersbedingten organ-dysfunktionen, altersbedingten erkrankungen und zur lebensverlängerung

Publications (2)

Publication Number Publication Date
HRP20010470A2 HRP20010470A2 (en) 2002-06-30
HRPK20010470B1 true HRPK20010470B1 (en) 2003-10-31

Family

ID=7892436

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20010470A HRPK20010470B1 (en) 1998-12-23 2001-06-20 The utilisation of inhibitors of the sodium hydrogen exchanger for producing a medicament for preventing organ dysfunctions and diseases related to a particular age and for prolonging life

Country Status (20)

Country Link
US (1) US6420430B1 (sk)
EP (1) EP1140056A2 (sk)
JP (1) JP2002533386A (sk)
KR (1) KR20010086152A (sk)
CN (1) CN1367689A (sk)
AR (1) AR021965A1 (sk)
AU (1) AU776761B2 (sk)
BR (1) BR9916505A (sk)
CA (1) CA2357837A1 (sk)
CZ (1) CZ20012309A3 (sk)
DE (1) DE19859727A1 (sk)
HR (1) HRPK20010470B1 (sk)
HU (1) HUP0104652A3 (sk)
IL (1) IL143372A0 (sk)
NO (1) NO20013145L (sk)
RU (1) RU2238721C2 (sk)
SK (1) SK9042001A3 (sk)
TR (1) TR200101803T2 (sk)
WO (1) WO2000038661A2 (sk)
ZA (1) ZA200104301B (sk)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6844361B2 (en) * 2002-02-04 2005-01-18 Aventis Pharma Deutschland Gmbh Pharmaceutical composition comprising a sodium hydrogen exchange inhibitor and an angiotensin converting enzyme inhibitor
AU2003244430A1 (en) * 2002-02-04 2003-09-02 Sanofi-Aventis Deutschland Gmbh Combination preparation of the sodium-hydrogen exchange inhibitor cariporide with ace inhibitors for preventing heart failure and other age-related dysfunctions of organs, age- related diseases and for prolonging lifespan
US7375138B2 (en) 2002-05-18 2008-05-20 Sanofi-Aventis Deutschland Gmbh Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them
FR2840302B1 (fr) * 2002-06-03 2004-07-16 Aventis Pharma Sa Derives d'isoindolones, procede de preparation et intermediaire de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
US6878748B2 (en) 2002-06-13 2005-04-12 Aventis Pharma Deutschland Gmbh Fluorinated cycloalkyl-derivatized benzoylguanidines, process for their preparation, their uses as medicament, and medicament containing them
EP1646371A4 (en) * 2003-06-26 2010-09-22 Biotron Ltd ANTIVIRAL COMPOSITIONS AND METHODS
US7947897B2 (en) * 2005-11-02 2011-05-24 The Trustees Of Princeton University Organic photovoltaic cells utilizing ultrathin sensitizing layer
US8017863B2 (en) * 2005-11-02 2011-09-13 The Regents Of The University Of Michigan Polymer wrapped carbon nanotube near-infrared photoactive devices
US8013240B2 (en) * 2005-11-02 2011-09-06 The Trustees Of Princeton University Organic photovoltaic cells utilizing ultrathin sensitizing layer
KR101042078B1 (ko) * 2009-01-13 2011-06-16 한국항공우주산업 주식회사 치공구 제작용 수평 측면 가공 치구
CN104103253B (zh) 2014-07-04 2016-08-17 京东方科技集团股份有限公司 发射电极扫描电路、阵列基板和显示装置

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2097409T3 (es) * 1992-09-22 1997-04-01 Hoechst Ag Benzoilguanidinas, procedimiento para su preparacion, asi como su empleo como antiarritmicos.
EP0590455B1 (en) * 1992-09-28 2000-12-27 Hoechst Aktiengesellschaft Antiarrhythmic and cardioprotective substituted 1(2H)-isoquinolines, process for their production, medicament containing them and their use for the production of a medicament for combating heart failures
SE508028C2 (sv) * 1993-05-12 1998-08-10 Moelnlycke Ab Midjebälte för absorberande plagg
DE4328352A1 (de) 1993-08-24 1995-03-02 Hoechst Ag Substituierte N,N'-Di-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
US5506065A (en) 1994-02-25 1996-04-09 Whitehead Alenia Sistemi Subacquei S.P.A. Electrolyte-activated battery
DE4430861A1 (de) 1994-08-31 1996-03-07 Merck Patent Gmbh Heterocyclyl-benzoylguanidine
DE19502644A1 (de) * 1995-01-28 1996-08-01 Merck Patent Gmbh 4-Amino-benzoylguanidin-Derivate
DE19502895A1 (de) * 1995-01-31 1996-08-01 Merck Patent Gmbh 4-Mercapto-benzoylguanidin-Derivate
DE69603771T2 (de) * 1995-04-18 2000-09-07 Hoechst Ag Substituierte Indenoylguanidines mit antiarrhythmischer und cardioprotektiver Wirkung
EP0765867A1 (de) 1995-09-27 1997-04-02 Hoechst Aktiengesellschaft Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Antiarrhytmika oder Diagnostikum sowie sie enthaltendes Medikament
DE19542306A1 (de) * 1995-11-14 1997-05-15 Hoechst Ag Sulfonylamino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19621319A1 (de) 1996-05-28 1997-12-04 Hoechst Ag Bis-ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19622222A1 (de) * 1996-06-03 1997-12-04 Hoechst Ag Verwendung von Inhibitoren des zellulären Na·+·/H·+·-Exchangers (NHE) zur Herstellung eines Medikament zur Normalisierung der Serumlipide
JP2002502414A (ja) * 1997-06-02 2002-01-22 藤沢薬品工業株式会社 細胞中のＮａ▲上＋▼／Ｈ▲上＋▼交換の阻害剤としてのグアニジン誘導体
DE19734693A1 (de) * 1997-08-11 1998-01-22 Hoechst Marion Roussel De Gmbh Verwendung von Cariporide als Inhibitor des zellulären NA+/H+-Exchangers (NHE) zur Herstellung eines Medikaments zur Behandlung von cardialen und nichtcardialen Krankheiten
US6011059A (en) * 1997-12-24 2000-01-04 Bristol-Myers Squibb Company Acyl guanidine sodium/proton exchange inhibitors and method
CA2260499A1 (en) * 1998-01-29 1999-07-29 Sumitomo Pharmaceuticals Company Limited Pharmaceutical compositions for the treatment of ischemic brain damage

Also Published As

Publication number Publication date
HRP20010470A2 (en) 2002-06-30
CN1367689A (zh) 2002-09-04
AU1657600A (en) 2000-07-31
AU776761B2 (en) 2004-09-23
HUP0104652A3 (en) 2002-09-30
CZ20012309A3 (cs) 2001-09-12
HUP0104652A2 (hu) 2002-03-28
RU2001120358A (ru) 2005-12-10
BR9916505A (pt) 2001-11-20
JP2002533386A (ja) 2002-10-08
WO2000038661A3 (de) 2000-11-09
NO20013145L (no) 2001-08-22
DE19859727A1 (de) 2000-06-29
KR20010086152A (ko) 2001-09-08
WO2000038661A2 (de) 2000-07-06
TR200101803T2 (tr) 2001-10-22
NO20013145D0 (no) 2001-06-22
EP1140056A2 (de) 2001-10-10
AR021965A1 (es) 2002-09-04
ZA200104301B (en) 2003-02-20
CA2357837A1 (en) 2000-07-06
US6420430B1 (en) 2002-07-16
IL143372A0 (en) 2002-04-21
RU2238721C2 (ru) 2004-10-27
SK9042001A3 (en) 2001-12-03

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
AKOB Publication of a request for the grant of a patent not including a substantive examination of a patent application (a consensual patent)
PKB1 Consensual patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20041019

Year of fee payment: 6

PBKO Lapse due to non-payment of renewal fee for consensual patent

Effective date: 20051209