IL125114A0 - Use of inhibitor of the cellular na+/h+ exchanger (nhe) for the production of a medicament for respiratory stimulation - Google Patents
Use of inhibitor of the cellular na+/h+ exchanger (nhe) for the production of a medicament for respiratory stimulationInfo
- Publication number
- IL125114A0 IL125114A0 IL12511496A IL12511496A IL125114A0 IL 125114 A0 IL125114 A0 IL 125114A0 IL 12511496 A IL12511496 A IL 12511496A IL 12511496 A IL12511496 A IL 12511496A IL 125114 A0 IL125114 A0 IL 125114A0
- Authority
- IL
- Israel
- Prior art keywords
- nhe
- medicament
- exchanger
- inhibitor
- cellular
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60L—PROPULSION OF ELECTRICALLY-PROPELLED VEHICLES; SUPPLYING ELECTRIC POWER FOR AUXILIARY EQUIPMENT OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRODYNAMIC BRAKE SYSTEMS FOR VEHICLES IN GENERAL; MAGNETIC SUSPENSION OR LEVITATION FOR VEHICLES; MONITORING OPERATING VARIABLES OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRIC SAFETY DEVICES FOR ELECTRICALLY-PROPELLED VEHICLES
- B60L50/00—Electric propulsion with power supplied within the vehicle
- B60L50/50—Electric propulsion with power supplied within the vehicle using propulsion power supplied by batteries or fuel cells
- B60L50/60—Electric propulsion with power supplied within the vehicle using propulsion power supplied by batteries or fuel cells using power supplied by batteries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60L—PROPULSION OF ELECTRICALLY-PROPELLED VEHICLES; SUPPLYING ELECTRIC POWER FOR AUXILIARY EQUIPMENT OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRODYNAMIC BRAKE SYSTEMS FOR VEHICLES IN GENERAL; MAGNETIC SUSPENSION OR LEVITATION FOR VEHICLES; MONITORING OPERATING VARIABLES OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRIC SAFETY DEVICES FOR ELECTRICALLY-PROPELLED VEHICLES
- B60L7/00—Electrodynamic brake systems for vehicles in general
- B60L7/10—Dynamic electric regenerative braking
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60L—PROPULSION OF ELECTRICALLY-PROPELLED VEHICLES; SUPPLYING ELECTRIC POWER FOR AUXILIARY EQUIPMENT OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRODYNAMIC BRAKE SYSTEMS FOR VEHICLES IN GENERAL; MAGNETIC SUSPENSION OR LEVITATION FOR VEHICLES; MONITORING OPERATING VARIABLES OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRIC SAFETY DEVICES FOR ELECTRICALLY-PROPELLED VEHICLES
- B60L7/00—Electrodynamic brake systems for vehicles in general
- B60L7/10—Dynamic electric regenerative braking
- B60L7/16—Dynamic electric regenerative braking for vehicles comprising converters between the power source and the motor
-
- E—FIXED CONSTRUCTIONS
- E01—CONSTRUCTION OF ROADS, RAILWAYS, OR BRIDGES
- E01C—CONSTRUCTION OF, OR SURFACES FOR, ROADS, SPORTS GROUNDS, OR THE LIKE; MACHINES OR AUXILIARY TOOLS FOR CONSTRUCTION OR REPAIR
- E01C19/00—Machines, tools or auxiliary devices for preparing or distributing paving materials, for working the placed materials, or for forming, consolidating, or finishing the paving
- E01C19/22—Machines, tools or auxiliary devices for preparing or distributing paving materials, for working the placed materials, or for forming, consolidating, or finishing the paving for consolidating or finishing laid-down unset materials
- E01C19/23—Rollers therefor; Such rollers usable also for compacting soil
- E01C19/26—Rollers therefor; Such rollers usable also for compacting soil self-propelled or fitted to road vehicles
-
- E—FIXED CONSTRUCTIONS
- E01—CONSTRUCTION OF ROADS, RAILWAYS, OR BRIDGES
- E01C—CONSTRUCTION OF, OR SURFACES FOR, ROADS, SPORTS GROUNDS, OR THE LIKE; MACHINES OR AUXILIARY TOOLS FOR CONSTRUCTION OR REPAIR
- E01C19/00—Machines, tools or auxiliary devices for preparing or distributing paving materials, for working the placed materials, or for forming, consolidating, or finishing the paving
- E01C19/22—Machines, tools or auxiliary devices for preparing or distributing paving materials, for working the placed materials, or for forming, consolidating, or finishing the paving for consolidating or finishing laid-down unset materials
- E01C19/23—Rollers therefor; Such rollers usable also for compacting soil
- E01C19/28—Vibrated rollers or rollers subjected to impacts, e.g. hammering blows
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19548812A DE19548812A1 (en) | 1995-12-27 | 1995-12-27 | Use of inhibitors of the cellular Na · + · / H · + · exchanger (NHE) for the manufacture of a medicament for respiratory stimulation |
PCT/EP1996/005614 WO1997024113A1 (en) | 1995-12-27 | 1996-12-13 | USE OF INHIBITORS OF THE CELLULAR Na+/H+ EXCHANGER (NHE) FOR THE PREPARATION OF A DRUG FOR RESPIRATORY STIMULATION |
Publications (1)
Publication Number | Publication Date |
---|---|
IL125114A0 true IL125114A0 (en) | 1999-01-26 |
Family
ID=7781474
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12511496A IL125114A0 (en) | 1995-12-27 | 1996-12-13 | Use of inhibitor of the cellular na+/h+ exchanger (nhe) for the production of a medicament for respiratory stimulation |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0869779A1 (en) |
KR (1) | KR19990076802A (en) |
CN (1) | CN1207676A (en) |
AU (1) | AU717247B2 (en) |
BR (1) | BR9612287A (en) |
CA (1) | CA2241531A1 (en) |
CZ (1) | CZ202198DA3 (en) |
DE (1) | DE19548812A1 (en) |
HU (1) | HUP9900807A3 (en) |
IL (1) | IL125114A0 (en) |
MX (1) | MX9805141A (en) |
NO (1) | NO982989L (en) |
PL (1) | PL327693A1 (en) |
SK (1) | SK88398A3 (en) |
TR (1) | TR199801235T2 (en) |
WO (1) | WO1997024113A1 (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9504537D0 (en) * | 1995-12-19 | 1995-12-19 | Jan Hedner | Ways of treating and diagnosing respiratory disorders during sleep and means of performing the method |
DE19945302A1 (en) * | 1999-09-22 | 2001-03-29 | Merck Patent Gmbh | Biphenyl derivatives as NHE-3 inhibitors |
DE10060292A1 (en) * | 2000-12-05 | 2002-06-20 | Aventis Pharma Gmbh | Use of substituted benzimidazoles for the manufacture of a medicament for the treatment of diseases which can be influenced by inhibition of the Na + / H + exchanger and medicament containing them |
DE10163239A1 (en) * | 2001-12-21 | 2003-07-10 | Aventis Pharma Gmbh | Substituted imidazolidines, process for their preparation, their use as medicaments or diagnostic agents, and medicaments containing them |
WO2018129556A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
LT2384318T (en) | 2008-12-31 | 2018-02-26 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
US10376481B2 (en) | 2012-08-21 | 2019-08-13 | Ardelyx, Inc. | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
AU2013304812B2 (en) | 2012-08-21 | 2016-06-09 | Ardelyx, Inc. | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
EP3988120A1 (en) | 2013-04-12 | 2022-04-27 | Ardelyx, Inc. | Nhe3-binding compounds and methods for inhibiting phosphate transport |
SG11201700398RA (en) | 2014-07-25 | 2017-02-27 | Taisho Pharmaceutical Co Ltd | Phenyl tetrahydroisoquinoline compound substituted with heteroaryl |
JP7292207B2 (en) | 2017-01-09 | 2023-06-16 | アルデリックス, インコーポレイテッド | Compounds Useful for Treating Gastrointestinal Disorders |
KR20190128626A (en) | 2017-01-09 | 2019-11-18 | 알데릭스, 인코포레이티드 | Inhibitors of NHE-mediated reverse transport |
KR20200074085A (en) | 2017-08-04 | 2020-06-24 | 알데릭스, 인코포레이티드 | Glycyrrhetic acid derivatives for the treatment of hyperkalemia |
CN114008065A (en) | 2019-02-07 | 2022-02-01 | 阿德利克斯股份有限公司 | Glycyrrhetinic acid derivatives for treating hyperkalemia |
US20200368223A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Methods for inhibiting phosphate transport |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4325822A1 (en) * | 1993-07-31 | 1995-02-02 | Hoechst Ag | Substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent, and medicament containing them |
EP0639573A1 (en) * | 1993-08-03 | 1995-02-22 | Hoechst Aktiengesellschaft | Benzocondensed five membered heterocycles, process of their preparation, their use as drug, as diagnostic means and pharmaceuticals containing it |
DE4337609A1 (en) * | 1993-11-04 | 1995-05-11 | Boehringer Ingelheim Kg | Novel pyrazinecarboxamide derivatives, their preparation and their use in medicines |
DE4415873A1 (en) * | 1994-05-05 | 1995-11-09 | Hoechst Ag | Substituted bicyclic heteroaroylguanidines, process for their preparation, their use as medicament or diagnostic agent and medicament containing them |
-
1995
- 1995-12-27 DE DE19548812A patent/DE19548812A1/en not_active Withdrawn
-
1996
- 1996-12-13 WO PCT/EP1996/005614 patent/WO1997024113A1/en not_active Application Discontinuation
- 1996-12-13 TR TR1998/01235T patent/TR199801235T2/en unknown
- 1996-12-13 IL IL12511496A patent/IL125114A0/en unknown
- 1996-12-13 SK SK883-98A patent/SK88398A3/en unknown
- 1996-12-13 EP EP96943956A patent/EP0869779A1/en not_active Withdrawn
- 1996-12-13 KR KR1019980704927A patent/KR19990076802A/en not_active Application Discontinuation
- 1996-12-13 BR BR9612287-0A patent/BR9612287A/en unknown
- 1996-12-13 CA CA002241531A patent/CA2241531A1/en not_active Abandoned
- 1996-12-13 PL PL96327693A patent/PL327693A1/en unknown
- 1996-12-13 AU AU13720/97A patent/AU717247B2/en not_active Ceased
- 1996-12-13 CN CN96199403A patent/CN1207676A/en active Pending
- 1996-12-13 HU HU9900807A patent/HUP9900807A3/en unknown
-
1998
- 1998-06-24 MX MX9805141A patent/MX9805141A/en unknown
- 1998-06-26 NO NO982989A patent/NO982989L/en not_active Application Discontinuation
-
2021
- 2021-03-03 CZ CZ982021A patent/CZ202198DA3/en unknown
Also Published As
Publication number | Publication date |
---|---|
TR199801235T2 (en) | 1998-10-21 |
CA2241531A1 (en) | 1997-07-10 |
CN1207676A (en) | 1999-02-10 |
SK88398A3 (en) | 1999-03-12 |
KR19990076802A (en) | 1999-10-15 |
NO982989L (en) | 1998-08-06 |
EP0869779A1 (en) | 1998-10-14 |
HUP9900807A2 (en) | 1999-07-28 |
HUP9900807A3 (en) | 2000-11-28 |
PL327693A1 (en) | 1998-12-21 |
BR9612287A (en) | 2005-05-24 |
MX9805141A (en) | 1998-10-31 |
AU717247B2 (en) | 2000-03-23 |
DE19548812A1 (en) | 1997-07-03 |
CZ202198DA3 (en) | 1998-11-11 |
AU1372097A (en) | 1997-07-28 |
WO1997024113A1 (en) | 1997-07-10 |
NO982989D0 (en) | 1998-06-26 |
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