HRP980482A2 - 5,5-disubstituted-1,5-dihydro-4,1-benzoxazepin-2(3h)-ones useful as hiv reverse transcriptase inhibitors - Google Patents

5,5-disubstituted-1,5-dihydro-4,1-benzoxazepin-2(3h)-ones useful as hiv reverse transcriptase inhibitors

Info

Publication number
HRP980482A2
HRP980482A2 HR60/057,431A HRP980482A HRP980482A2 HR P980482 A2 HRP980482 A2 HR P980482A2 HR P980482 A HRP980482 A HR P980482A HR P980482 A2 HRP980482 A2 HR P980482A2
Authority
HR
Croatia
Prior art keywords
dihydro
trifluoromethyl
benzoxazepin
chloro
rel
Prior art date
Application number
HR60/057,431A
Other languages
English (en)
Croatian (hr)
Inventor
James David Rodgers
Original Assignee
James David Rodgers
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by James David Rodgers filed Critical James David Rodgers
Publication of HRP980482A2 publication Critical patent/HRP980482A2/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
HR60/057,431A 1997-09-02 1998-09-01 5,5-disubstituted-1,5-dihydro-4,1-benzoxazepin-2(3h)-ones useful as hiv reverse transcriptase inhibitors HRP980482A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5743197P 1997-09-02 1997-09-02

Publications (1)

Publication Number Publication Date
HRP980482A2 true HRP980482A2 (en) 1999-10-31

Family

ID=22010528

Family Applications (1)

Application Number Title Priority Date Filing Date
HR60/057,431A HRP980482A2 (en) 1997-09-02 1998-09-01 5,5-disubstituted-1,5-dihydro-4,1-benzoxazepin-2(3h)-ones useful as hiv reverse transcriptase inhibitors

Country Status (12)

Country Link
US (2) US6140320A (xx)
EP (1) EP1009742A1 (xx)
JP (1) JP2001514256A (xx)
CN (1) CN1268944A (xx)
AR (1) AR015163A1 (xx)
AU (1) AU9023998A (xx)
BR (1) BR9814933A (xx)
CA (1) CA2303295A1 (xx)
HR (1) HRP980482A2 (xx)
TW (1) TW564248B (xx)
WO (1) WO1999011635A1 (xx)
ZA (1) ZA987539B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6943097B2 (en) * 2003-08-19 2005-09-13 International Business Machines Corporation Atomic layer deposition of metallic contacts, gates and diffusion barriers
US20070037894A1 (en) * 2003-09-19 2007-02-15 Hahnfeld Jerry L Multifunctional menomers and polyarylene compsotions therefrom
EP1666066A4 (en) * 2003-09-19 2007-03-28 Eisai R&D Man Co Ltd DRUG AGAINST THE DOWN SYNDROME
US7323455B2 (en) 2004-03-24 2008-01-29 Wyeth 7-aryl 1,5-dihydro-4,1-benzoxazepin-2(3H)-one derivatives and their use as progesterone receptor modulators
CN103254087B (zh) * 2013-06-07 2015-03-18 郑州大学 依非韦伦中间体的制备方法
WO2023192430A1 (en) * 2022-03-30 2023-10-05 University Of Florida Research Foundation, Incorported Compounds for treating psychostimulant misuse

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4374842A (en) * 1980-04-18 1983-02-22 Shionogi & Co., Ltd. 4,1-Benzoxazepines and compositions
EP0142361B1 (en) * 1983-11-17 1988-05-11 The Upjohn Company N-substituted-5-phenyl-4,1-benzoxazepin-2(3h)-ones having therapeutic utility
EP0417534A1 (en) * 1989-08-29 1991-03-20 Boehringer Ingelheim Pharmaceuticals Inc. Pyrido[2,3-b][1,4]benzoxazepin (and thiazepin)-6(5H)-ones and thiones and their use in the prevention or treatment of AIDS
SG48855A1 (en) * 1992-04-20 1998-05-18 Takeda Chemical Industries Ltd 4,1-benzoxazepin derivatives and their use
US5665720A (en) * 1992-08-07 1997-09-09 Merck & Co., Inc. Benzoxazinones as inhibitors of HIV reverse transcriptase
WO1995020389A1 (en) * 1994-01-28 1995-08-03 Merck & Co., Inc. Benzoxazinones as inhibitors of hiv reverse transcriptase
JPH08259447A (ja) * 1995-03-24 1996-10-08 Takeda Chem Ind Ltd コレシストキニン拮抗剤
ATE248826T1 (de) * 1996-10-02 2003-09-15 Bristol Myers Squibb Pharma Co 4,4-disubstituierte 1,4-dihydro-2h-3,1-benzoxazin-2-one die anwendbar sind als hiv- reverstranskriptase-inhibitoren, zwischenprodukte und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
AR015163A1 (es) 2001-04-18
WO1999011635A1 (en) 1999-03-11
US6489320B1 (en) 2002-12-03
US6140320A (en) 2000-10-31
AU9023998A (en) 1999-03-22
JP2001514256A (ja) 2001-09-11
TW564248B (en) 2003-12-01
BR9814933A (pt) 2001-01-30
ZA987539B (en) 2000-02-21
EP1009742A1 (en) 2000-06-21
CA2303295A1 (en) 1999-03-11
CN1268944A (zh) 2000-10-04

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Legal Events

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