HRP970125B1 - Ortho substituted benzoylguanidines, processes for their preparation, their use as a medicament or diagnostic agent and a medicament containing them - Google Patents

Ortho substituted benzoylguanidines, processes for their preparation, their use as a medicament or diagnostic agent and a medicament containing them

Info

Publication number
HRP970125B1
HRP970125B1 HR970125A HRP970125A HRP970125B1 HR P970125 B1 HRP970125 B1 HR P970125B1 HR 970125 A HR970125 A HR 970125A HR P970125 A HRP970125 A HR P970125A HR P970125 B1 HRP970125 B1 HR P970125B1
Authority
HR
Croatia
Prior art keywords
medicament
processes
preparation
diagnostic agent
ortho substituted
Prior art date
Application number
HR970125A
Other languages
English (en)
Inventor
Udo Albus
Joachim Brendel
Heinz-Werner Kleemann
Hans-Jochen Lang
Wolfgang Scholz
Jan-Robert Schwark
Andreas Weichert
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of HRP970125A2 publication Critical patent/HRP970125A2/xx
Publication of HRP970125B1 publication Critical patent/HRP970125B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HR970125A 1996-03-04 1997-03-03 Ortho substituted benzoylguanidines, processes for their preparation, their use as a medicament or diagnostic agent and a medicament containing them HRP970125B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19608161A DE19608161A1 (de) 1996-03-04 1996-03-04 Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (2)

Publication Number Publication Date
HRP970125A2 HRP970125A2 (en) 1998-04-30
HRP970125B1 true HRP970125B1 (en) 2002-06-30

Family

ID=7787087

Family Applications (1)

Application Number Title Priority Date Filing Date
HR970125A HRP970125B1 (en) 1996-03-04 1997-03-03 Ortho substituted benzoylguanidines, processes for their preparation, their use as a medicament or diagnostic agent and a medicament containing them

Country Status (30)

Country Link
US (1) US6262123B1 (ja)
EP (1) EP0794172B1 (ja)
JP (1) JP4039586B2 (ja)
KR (1) KR970065511A (ja)
CN (1) CN1071318C (ja)
AR (1) AR006051A1 (ja)
AT (1) ATE207462T1 (ja)
AU (1) AU707619B2 (ja)
BR (1) BR9701159A (ja)
CA (1) CA2198980A1 (ja)
CZ (1) CZ293144B6 (ja)
DE (2) DE19608161A1 (ja)
DK (1) DK0794172T3 (ja)
ES (1) ES2166481T3 (ja)
HR (1) HRP970125B1 (ja)
HU (1) HUP9700542A3 (ja)
ID (1) ID16106A (ja)
IL (1) IL120358A (ja)
MX (1) MX9701619A (ja)
MY (1) MY116861A (ja)
NO (1) NO308793B1 (ja)
NZ (1) NZ314325A (ja)
PL (1) PL185751B1 (ja)
PT (1) PT794172E (ja)
RU (1) RU2212400C2 (ja)
SI (1) SI0794172T1 (ja)
SK (1) SK283934B6 (ja)
TR (1) TR199700131A2 (ja)
TW (1) TW440558B (ja)
ZA (1) ZA971815B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10001879A1 (de) * 2000-01-19 2001-07-19 Aventis Pharma Gmbh Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
CN100371328C (zh) * 2006-01-19 2008-02-27 中国药科大学 取代苯甲酰基胍衍生物、其制备方法及其医药用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW250477B (ja) 1992-12-15 1995-07-01 Hoechst Ag
ATE157351T1 (de) 1993-02-20 1997-09-15 Hoechst Ag Substituierte benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament, als inhibitoren des zellulären na+/h+-austauschs oder als diagnostikum sowie sie enthaltendes medikament
DE4318756A1 (de) 1993-06-05 1994-12-08 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4404183A1 (de) * 1994-02-10 1995-08-17 Merck Patent Gmbh 4-Amino-1-piperidylbenzoylguanidine
DE4417004A1 (de) 1994-05-13 1995-11-16 Hoechst Ag Perfluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4421495A1 (de) * 1994-06-20 1995-12-21 Merck Patent Gmbh Heterocyclyloxy-benzoylguanidine
DE4430213A1 (de) * 1994-08-28 1996-02-29 Merck Patent Gmbh Arylbenzoylguanidine
DE4430861A1 (de) * 1994-08-31 1996-03-07 Merck Patent Gmbh Heterocyclyl-benzoylguanidine
DE19517848A1 (de) * 1995-05-16 1996-11-21 Merck Patent Gmbh Fluorhaltige Benzoylguanidine
DE19531138A1 (de) * 1995-08-24 1997-02-27 Merck Patent Gmbh Alkenyl-benzoylguanidin-Derivate
DE19624178A1 (de) * 1996-06-18 1998-01-08 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
HRP970125A2 (en) 1998-04-30
HUP9700542A3 (en) 1998-01-28
AR006051A1 (es) 1999-07-21
ES2166481T3 (es) 2002-04-16
HUP9700542A1 (en) 1997-12-29
SK27697A3 (en) 1997-11-05
CZ293144B6 (cs) 2004-02-18
US6262123B1 (en) 2001-07-17
EP0794172B1 (de) 2001-10-24
TR199700131A2 (tr) 1997-09-21
ID16106A (id) 1997-09-04
NZ314325A (en) 1998-02-26
PL318415A1 (en) 1997-09-15
TW440558B (en) 2001-06-16
IL120358A (en) 2002-04-21
RU2212400C2 (ru) 2003-09-20
ATE207462T1 (de) 2001-11-15
SI0794172T1 (en) 2002-10-31
CN1071318C (zh) 2001-09-19
NO970963D0 (no) 1997-03-03
CZ65497A3 (cs) 1998-05-13
ZA971815B (en) 1997-09-04
MX9701619A (es) 1998-04-30
BR9701159A (pt) 1998-12-15
CN1160042A (zh) 1997-09-24
JP4039586B2 (ja) 2008-01-30
PT794172E (pt) 2002-02-28
HU9700542D0 (en) 1997-04-28
JPH107644A (ja) 1998-01-13
PL185751B1 (pl) 2003-07-31
CA2198980A1 (en) 1997-09-04
MY116861A (en) 2004-04-30
DK0794172T3 (da) 2002-02-11
SK283934B6 (sk) 2004-05-04
EP0794172A1 (de) 1997-09-10
AU707619B2 (en) 1999-07-15
IL120358A0 (en) 1997-07-13
AU1499797A (en) 1997-09-11
DE19608161A1 (de) 1997-09-11
DE59705019D1 (de) 2001-11-29
NO970963L (no) 1997-09-05
NO308793B1 (no) 2000-10-30
KR970065511A (ko) 1997-10-13

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Payment date: 20050215

Year of fee payment: 9

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Effective date: 20060304