HRP20231065T1 - Postupci koji uključuju alvelestat inhibitor neutrofilne elastaze za liječenje respiratorne bolesti posredovane putem nedostatka alfa-1 antitripsina - Google Patents

Postupci koji uključuju alvelestat inhibitor neutrofilne elastaze za liječenje respiratorne bolesti posredovane putem nedostatka alfa-1 antitripsina Download PDF

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Publication number
HRP20231065T1
HRP20231065T1 HRP20231065TT HRP20231065T HRP20231065T1 HR P20231065 T1 HRP20231065 T1 HR P20231065T1 HR P20231065T T HRP20231065T T HR P20231065TT HR P20231065 T HRP20231065 T HR P20231065T HR P20231065 T1 HRP20231065 T1 HR P20231065T1
Authority
HR
Croatia
Prior art keywords
salt
alvelestat
disease
administration
day
Prior art date
Application number
HRP20231065TT
Other languages
English (en)
Croatian (hr)
Inventor
Jacqueline PARKIN
Original Assignee
Mereo Biopharma 4 Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=78083570&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20231065(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB2005520.8A external-priority patent/GB202005520D0/en
Priority claimed from GBGB2005519.0A external-priority patent/GB202005519D0/en
Application filed by Mereo Biopharma 4 Limited filed Critical Mereo Biopharma 4 Limited
Publication of HRP20231065T1 publication Critical patent/HRP20231065T1/hr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
HRP20231065TT 2020-04-16 2021-03-16 Postupci koji uključuju alvelestat inhibitor neutrofilne elastaze za liječenje respiratorne bolesti posredovane putem nedostatka alfa-1 antitripsina HRP20231065T1 (hr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB2005520.8A GB202005520D0 (en) 2020-04-16 2020-04-16 Elastase inhibition
GBGB2005519.0A GB202005519D0 (en) 2020-04-16 2020-04-16 Elastase inhibition
US202062706195P 2020-08-04 2020-08-04
PCT/GB2021/050653 WO2021209739A1 (en) 2020-04-16 2021-03-16 Methods involving neutrophil elastase inhibitor alvelestat for treating respiratory disease mediated by alpha-1 antitrypsin deficiency
EP21714345.2A EP4106757B1 (en) 2020-04-16 2021-03-16 Methods involving neutrophil elastase inhibitor alvelestat for treating respiratory disease mediated by alpha-1 antitrypsin deficiency

Publications (1)

Publication Number Publication Date
HRP20231065T1 true HRP20231065T1 (hr) 2023-12-22

Family

ID=78083570

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20231065TT HRP20231065T1 (hr) 2020-04-16 2021-03-16 Postupci koji uključuju alvelestat inhibitor neutrofilne elastaze za liječenje respiratorne bolesti posredovane putem nedostatka alfa-1 antitripsina

Country Status (16)

Country Link
US (2) US20230218596A1 (enExample)
EP (2) EP4252850A3 (enExample)
JP (2) JP2023522010A (enExample)
AU (1) AU2021256835A1 (enExample)
DK (1) DK4106757T3 (enExample)
ES (1) ES2962498T3 (enExample)
FI (1) FI4106757T3 (enExample)
HR (1) HRP20231065T1 (enExample)
HU (1) HUE064089T2 (enExample)
IL (1) IL297211B2 (enExample)
LT (1) LT4106757T (enExample)
MX (1) MX2022012942A (enExample)
PL (1) PL4106757T3 (enExample)
PT (1) PT4106757T (enExample)
SI (1) SI4106757T1 (enExample)
WO (2) WO2021209740A1 (enExample)

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CA3179317A1 (en) * 2020-04-20 2021-10-28 Lloyd Hung Loi TRAN Methods for the prophylaxis and treatment of covid and covid-19
JP2024520818A (ja) * 2021-06-08 2024-05-24 フォアシー ファーマシューティカルズ カンパニー リミテッド 急性呼吸促迫症候群を処置するためのｍｍｐ阻害薬の使用
US20230285523A1 (en) * 2021-12-20 2023-09-14 Tiakis Biotech Ag Use of elafin in the treatment of covid-19
CN116407640B (zh) * 2023-03-03 2025-10-31 河南真实生物科技有限公司 包含阿兹夫定和化疗试剂的抗肿瘤药物组合物
WO2025056602A1 (en) * 2023-09-11 2025-03-20 Elastin Biosciences Ltd. Pharmaceutical compositions and use thereof in treatment of conditions and diseases related to elastin deficiency and/or aging
EP4791400A1 (en) 2023-10-11 2026-08-19 Mereo Biopharma 4 Limited Alvelestat and alpha- 1 antitrypsin for treating respiratory disorders
AU2024406526A1 (en) 2023-12-21 2026-04-16 Mereo Biopharma 4 Limited Use of alvelestat in specific patients
GB202319953D0 (en) 2023-12-22 2024-02-07 Mereo Biopharma 4 Ltd Tablet formulations involving alvelestat
KR20250172196A (ko) * 2024-05-31 2025-12-09 고려대학교 산학협력단 폐 계면활성제 및 항섬유화제를 포함하는 폐섬유증의 예방 또는 치료용 조성물 및 이의 제조방법
CN119548503B (zh) * 2024-10-11 2026-07-03 哈尔滨医科大学 Axl抑制剂在制备治疗心力衰竭药物中的用途
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Also Published As

Publication number Publication date
US20230190723A1 (en) 2023-06-22
SI4106757T1 (sl) 2023-11-30
IL297211B1 (en) 2025-08-01
LT4106757T (lt) 2023-11-10
JP2023522010A (ja) 2023-05-26
HUE064089T2 (hu) 2024-02-28
IL297211B2 (en) 2025-12-01
WO2021209740A1 (en) 2021-10-21
EP4252850A3 (en) 2023-11-15
FI4106757T3 (fi) 2023-10-23
EP4252850A2 (en) 2023-10-04
IL297211A (en) 2022-12-01
ES2962498T3 (es) 2024-03-19
EP4106757B1 (en) 2023-08-23
WO2021209739A1 (en) 2021-10-21
PT4106757T (pt) 2023-11-17
DK4106757T3 (da) 2023-10-23
JP2026120579A (ja) 2026-07-22
US20230218596A1 (en) 2023-07-13
PL4106757T3 (pl) 2024-01-22
AU2021256835A1 (en) 2022-10-13
EP4106757A1 (en) 2022-12-28
MX2022012942A (es) 2023-01-11

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