HRP20210814T1 - Derivati piridokinazolina korisni kao inhibitori proteinskih kinaza - Google Patents

Derivati piridokinazolina korisni kao inhibitori proteinskih kinaza Download PDF

Info

Publication number
HRP20210814T1
HRP20210814T1 HRP20210814TT HRP20210814T HRP20210814T1 HR P20210814 T1 HRP20210814 T1 HR P20210814T1 HR P20210814T T HRP20210814T T HR P20210814TT HR P20210814 T HRP20210814 T HR P20210814T HR P20210814 T1 HRP20210814 T1 HR P20210814T1
Authority
HR
Croatia
Prior art keywords
pyrido
quinazoline
carboxamide
oxo
unbranched
Prior art date
Application number
HRP20210814TT
Other languages
English (en)
Croatian (hr)
Inventor
Guido Kurz
Juan CAMACHO GÓMEZ
Original Assignee
Oncostellae, S.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncostellae, S.L. filed Critical Oncostellae, S.L.
Publication of HRP20210814T1 publication Critical patent/HRP20210814T1/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24CDOMESTIC STOVES OR RANGES ; DETAILS OF DOMESTIC STOVES OR RANGES, OF GENERAL APPLICATION
    • F24C7/00Stoves or ranges heated by electric energy
    • F24C7/08Arrangement or mounting of control or safety devices
    • F24C7/082Arrangement or mounting of control or safety devices on ranges, e.g. control panels, illumination
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24CDOMESTIC STOVES OR RANGES ; DETAILS OF DOMESTIC STOVES OR RANGES, OF GENERAL APPLICATION
    • F24C7/00Stoves or ranges heated by electric energy
    • F24C7/08Arrangement or mounting of control or safety devices
    • F24C7/087Arrangement or mounting of control or safety devices of electric circuits regulating heat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Combustion & Propulsion (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HRP20210814TT 2017-06-01 2018-05-31 Derivati piridokinazolina korisni kao inhibitori proteinskih kinaza HRP20210814T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES201730759 2017-06-01
EP18759146.6A EP3632912B1 (en) 2017-06-01 2018-05-31 Pyridoquinazoline derivatives useful as protein kinase inhibitors
PCT/ES2018/070396 WO2018220252A1 (es) 2017-06-01 2018-05-31 Derivados de piridoquinazolina eficaces como inhibidores de proteína quinasa

Publications (1)

Publication Number Publication Date
HRP20210814T1 true HRP20210814T1 (hr) 2021-06-25

Family

ID=61569288

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20210814TT HRP20210814T1 (hr) 2017-06-01 2018-05-31 Derivati piridokinazolina korisni kao inhibitori proteinskih kinaza

Country Status (22)

Country Link
US (1) US11021479B2 (OSRAM)
EP (1) EP3632912B1 (OSRAM)
JP (1) JP7110335B2 (OSRAM)
KR (1) KR102629854B1 (OSRAM)
CN (1) CN111247143B (OSRAM)
AU (1) AU2018278283B2 (OSRAM)
CA (1) CA3066009A1 (OSRAM)
CY (1) CY1124087T1 (OSRAM)
DK (1) DK3632912T3 (OSRAM)
EA (1) EA037384B1 (OSRAM)
ES (1) ES2881960T3 (OSRAM)
HR (1) HRP20210814T1 (OSRAM)
HU (1) HUE054792T2 (OSRAM)
LT (1) LT3632912T (OSRAM)
MX (1) MX385475B (OSRAM)
PL (1) PL3632912T3 (OSRAM)
PT (1) PT3632912T (OSRAM)
RS (1) RS61833B1 (OSRAM)
SI (1) SI3632912T1 (OSRAM)
SM (1) SMT202100312T1 (OSRAM)
WO (1) WO2018220252A1 (OSRAM)
ZA (1) ZA201908372B (OSRAM)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7525609B2 (ja) 2020-01-31 2024-07-30 エルジー エナジー ソリューション リミテッド 多層構造の無機物層を含む分離膜一体型電極の製造方法及びそれによる分離膜一体型電極

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4551460A (en) 1982-05-10 1985-11-05 Hoffmann-La Roche Inc. Pyrido[2,1-b]quinazoline derivatives useful as agents for treatment of allergic conditions and vascular disorders involving thrombosis
EP0944628B1 (en) * 1996-11-26 2002-06-05 American Cyanamid Company Hetero-biaryl-pyridoquinazolinone derivatives as anti-cancer agents
US20050171172A1 (en) * 2003-11-13 2005-08-04 Ambit Biosciences Corporation Amide derivatives as PDGFR modulators
AU2008345225A1 (en) * 2007-12-21 2009-07-09 University Of Rochester Method for altering the lifespan of eukaryotic organisms
KR101361027B1 (ko) 2008-11-28 2014-02-11 코와 가부시키가이샤 피리딘-3-카르복시아미드 유도체
US11001581B2 (en) 2014-03-20 2021-05-11 The Johns Hopkins University and Lieber Institute, Inc. Compounds which inhibit RNA polymerase, compositions including such compounds, and their use

Also Published As

Publication number Publication date
RS61833B1 (sr) 2021-06-30
EA201992793A1 (ru) 2020-03-26
EA037384B1 (ru) 2021-03-23
CA3066009A1 (en) 2018-12-06
CN111247143B (zh) 2022-07-05
SMT202100312T1 (it) 2021-07-12
EP3632912B1 (en) 2021-03-17
JP7110335B2 (ja) 2022-08-01
ES2881960T3 (es) 2021-11-30
JP2020521817A (ja) 2020-07-27
MX385475B (es) 2025-03-18
CN111247143A (zh) 2020-06-05
US20200148676A1 (en) 2020-05-14
US11021479B2 (en) 2021-06-01
DK3632912T3 (da) 2021-05-10
MX2019014436A (es) 2020-02-10
AU2018278283B2 (en) 2021-06-17
KR20200011990A (ko) 2020-02-04
SI3632912T1 (sl) 2021-08-31
KR102629854B1 (ko) 2024-01-25
CY1124087T1 (el) 2022-05-27
PL3632912T3 (pl) 2021-09-06
LT3632912T (lt) 2021-06-10
PT3632912T (pt) 2021-06-02
HUE054792T2 (hu) 2021-09-28
EP3632912A1 (en) 2020-04-08
WO2018220252A1 (es) 2018-12-06
AU2018278283A1 (en) 2019-12-19
BR112019024892A2 (pt) 2020-06-16
ZA201908372B (en) 2021-04-28

Similar Documents

Publication Publication Date Title
JP7394820B2 (ja) Jak1選択的阻害剤
CA2931085C (en) Cyclic sulfone and sulfoximine analogs and uses thereof
CA2903288C (en) N-acyl-n'-(pyridin-2-yl) ureas and analogs exhibiting anti-cancer and anti-proliferative activities
ES2630705T3 (es) Compuestos de piridilo sustituidos con triazolilo útiles como inhibidores de cinasas
ES2823477T3 (es) Aril éteres y usos de los mismos
AU2018338098B2 (en) Cyclic iminopyrimidine derivatives as kinase inhibitors
JP6294954B2 (ja) P2x7調節物質
ME02672B (me) Fenil-3-aza-bicikl0[3.1.0]heks-3-il-metanoni i njihova primena kao medikament
JP2016534134A5 (OSRAM)
RU2019104890A (ru) Замещенные тиазолопиридиновые соединения в качестве ингибиторов malt1
ME02667B (me) Spiro-prstenasti spoj koji sadrži dušik i njegova upotreba u medicini
HRP20210869T1 (hr) Pripravci spojeva i njihova upotreba
CA2764728A1 (en) Janus kinase inhibitor compounds and methods
JP2006518341A (ja) ヒストンデアセチラーゼ(hdac)阻害剤としてのヒドロキサム酸誘導体
ES2989149T3 (es) Inhibidores de HAT p300/CBP
HRP20201985T1 (hr) Piridonski spoj kao c-met inhibitor
EP3191472A1 (en) Compounds and compositions as raf kinase inhibitors
JP2016501185A5 (OSRAM)
HRP20220472T1 (hr) Novi derivati heteroarilamida kao selektivni inhibitori histonskih deacetilaza 1 i 2 (hdac1-2)
HRP20180973T1 (hr) Supstituirani tiazolski ili oksazolski antagonisti p2x7 receptora
RU2016112963A (ru) Новые производные триазолопиразина и их применение
JP2019510801A5 (OSRAM)
WO2024120471A1 (en) Compounds targeting mutant of p53
HRP20210814T1 (hr) Derivati piridokinazolina korisni kao inhibitori proteinskih kinaza
JP6634157B2 (ja) ジアミノピリジン誘導体