HRP20210417T1 - Pripravci magnezija namijenjeni moduliranju farmakokinetike i farmakodinamike inzulina, te boli na mjestu injekcije - Google Patents

Pripravci magnezija namijenjeni moduliranju farmakokinetike i farmakodinamike inzulina, te boli na mjestu injekcije Download PDF

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Publication number
HRP20210417T1
HRP20210417T1 HRP20210417TT HRP20210417T HRP20210417T1 HR P20210417 T1 HRP20210417 T1 HR P20210417T1 HR P20210417T T HRP20210417T T HR P20210417TT HR P20210417 T HRP20210417 T HR P20210417T HR P20210417 T1 HRP20210417 T1 HR P20210417T1
Authority
HR
Croatia
Prior art keywords
magnesium
insulin
acid
formulation according
concentration
Prior art date
Application number
HRP20210417TT
Other languages
English (en)
Croatian (hr)
Inventor
Roderike Pohl
Robert Hauser
Ming Li
Bryan R. Wilson
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of HRP20210417T1 publication Critical patent/HRP20210417T1/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HRP20210417TT 2012-04-16 2013-04-16 Pripravci magnezija namijenjeni moduliranju farmakokinetike i farmakodinamike inzulina, te boli na mjestu injekcije HRP20210417T1 (hr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261624844P 2012-04-16 2012-04-16
US201261704066P 2012-09-21 2012-09-21
US13/826,806 US9381247B2 (en) 2012-04-16 2013-03-14 Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin and insulin analogs, and injection site pain
PCT/US2013/036742 WO2013158618A1 (en) 2012-04-16 2013-04-16 Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin and insulin analogs, and injection site pain
EP13721441.7A EP2838506B1 (en) 2012-04-16 2013-04-16 Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin, and injection site pain

Publications (1)

Publication Number Publication Date
HRP20210417T1 true HRP20210417T1 (hr) 2021-04-30

Family

ID=48326401

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20210417TT HRP20210417T1 (hr) 2012-04-16 2013-04-16 Pripravci magnezija namijenjeni moduliranju farmakokinetike i farmakodinamike inzulina, te boli na mjestu injekcije

Country Status (25)

Country Link
US (1) US9381247B2 (enExample)
EP (2) EP3827813A1 (enExample)
JP (2) JP6422855B2 (enExample)
KR (1) KR101966484B1 (enExample)
CN (1) CN104394847A (enExample)
AU (1) AU2013249495B2 (enExample)
CA (1) CA2869883A1 (enExample)
CY (1) CY1123825T1 (enExample)
DK (1) DK2838506T3 (enExample)
ES (1) ES2854874T3 (enExample)
HK (2) HK1203371A1 (enExample)
HR (1) HRP20210417T1 (enExample)
HU (1) HUE053303T2 (enExample)
IL (1) IL234987A0 (enExample)
IN (1) IN2014DN08417A (enExample)
LT (1) LT2838506T (enExample)
MX (1) MX2014012245A (enExample)
PL (1) PL2838506T3 (enExample)
PT (1) PT2838506T (enExample)
RS (1) RS61533B1 (enExample)
RU (1) RU2014145846A (enExample)
SG (1) SG11201406491PA (enExample)
SI (1) SI2838506T1 (enExample)
WO (1) WO2013158618A1 (enExample)
ZA (1) ZA201407410B (enExample)

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EP2919804B1 (fr) 2012-11-13 2018-01-31 Adocia Formulation à action rapide d'insuline comprenant un composé anionique substitué
CA2936563A1 (en) * 2014-01-13 2015-07-16 Thermalin Diabetes, Llc Rapid action insulin formulations and pharmaceutical delivery systems
WO2015120457A1 (en) * 2014-02-10 2015-08-13 Biodel Inc. Stabilized ultra-rapid-acting insulin formulations
TWI685348B (zh) * 2014-05-08 2020-02-21 美國禮來大藥廠 速效胰島素組合物
US9672328B2 (en) 2014-07-10 2017-06-06 Companion Medical, Inc. Medicine administering system including injection pen and companion device
AR102869A1 (es) 2014-12-16 2017-03-29 Lilly Co Eli Composiciones de insulina de rápida acción
JP2018505874A (ja) * 2015-01-20 2018-03-01 ケース ウェスタン リザーブ ユニバーシティCase Western Reserve University 選択的シグナリング特性及びより低い分裂促進性を有するインスリンアナログ
JO3749B1 (ar) * 2015-08-27 2021-01-31 Lilly Co Eli تركيبات إنسولين سريعة المفعول
EP3407940A4 (en) 2016-01-29 2019-09-04 Companion Medical, Inc. PURPOSES OF AUTOMATIC DRUG DISPOSAL
GB201607918D0 (en) 2016-05-06 2016-06-22 Arecor Ltd Novel formulations
EP4265296A3 (en) 2016-09-29 2023-12-20 Arecor Limited Pharmaceutical formulation comprising an insulin compound
GB201707189D0 (en) * 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
CA3065308C (en) 2017-06-01 2022-05-17 Eli Lilly And Company Rapid-acting insulin compositions
US11484657B2 (en) 2017-06-09 2022-11-01 Medtronic Minimed, Inc. Intelligent medication delivery systems and methods
EP3694583B1 (en) * 2017-10-12 2026-05-06 Medtronic MiniMed, Inc. Intelligent medication delivery systems and methods for dose recommendation and management
US11077243B2 (en) 2017-12-12 2021-08-03 Bigfoot Biomedical, Inc. Devices, systems, and methods for estimating active medication from injections
US11464459B2 (en) 2017-12-12 2022-10-11 Bigfoot Biomedical, Inc. User interface for diabetes management systems including flash glucose monitor
US11197964B2 (en) 2017-12-12 2021-12-14 Bigfoot Biomedical, Inc. Pen cap for medication injection pen having temperature sensor
US11083852B2 (en) 2017-12-12 2021-08-10 Bigfoot Biomedical, Inc. Insulin injection assistance systems, methods, and devices
US10987464B2 (en) 2017-12-12 2021-04-27 Bigfoot Biomedical, Inc. Pen cap for insulin injection pens and associated methods and systems
AU2018383731B2 (en) 2017-12-12 2024-11-07 Bigfoot Biomedical, Inc. Therapy management systems, methods, and devices
US11116899B2 (en) 2017-12-12 2021-09-14 Bigfoot Biomedical, Inc. User interface for diabetes management systems and devices
EP3773474B1 (en) 2018-04-04 2026-01-07 Arecor Limited Medical infusion pump system for the delivery of an insulin compound
US10898653B2 (en) 2018-05-08 2021-01-26 Companion Medical, Inc. Intelligent medication delivery systems and methods for dose setting and dispensing monitoring
US11664107B2 (en) 2018-05-08 2023-05-30 Medtronic Minimed, Inc. Intelligent medication delivery systems and methods using a prescription-regulated software application
USD893020S1 (en) 2018-05-11 2020-08-11 Companion Medical, Inc. Injection pen
USD892819S1 (en) 2018-06-20 2020-08-11 Companion Medical, Inc. Display screen with graphical user interface
US11587663B2 (en) 2018-06-20 2023-02-21 Medtronic Minimed, Inc. Intelligent medication delivery systems and methods for medicine dose calculation and reporting
FR3083985A1 (fr) 2018-07-23 2020-01-24 Adocia Dispositif pour injecter une solution d'insuline(s)
FR3083984A1 (fr) 2018-07-23 2020-01-24 Adocia Dispositif pour injecter une solution d'insuline(s)
WO2019243627A1 (fr) 2018-06-23 2019-12-26 Adocia Dispositif pour injecter une solution d'insuline(s)
US12205699B1 (en) 2018-10-30 2025-01-21 Bigfoot Biomedical, Inc. Method of pairing therapy devices using shared secrets, and related systems, methods and devices
US11948671B2 (en) 2019-04-11 2024-04-02 Medtronic Minimed, Inc. Intelligent accessories for medicine dispensing device
US12667674B2 (en) 2020-10-02 2026-06-30 Bigfoot Biomedical, Inc. Injection site determination systems and methods for injection site tracking and recommending injection sites
JP2023544832A (ja) * 2020-10-08 2023-10-25 ドクター メアリー モリス アンド アソシエイツ リミテッド ライアビリティ カンパニー 1型糖尿病の治療および予防のための方法および組成物
US11701473B2 (en) 2021-06-23 2023-07-18 Medtronic Minimed, Inc. Reusable injection pens

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DE69924232D1 (de) * 1998-01-09 2005-04-21 Novo Nordisk As Stabilisierte insulin-zubereitungen
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US20080096800A1 (en) 2004-03-12 2008-04-24 Biodel, Inc. Rapid mucosal gel or film insulin compositions
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TWI394580B (zh) 2008-04-28 2013-05-01 Halozyme Inc 超快起作用胰島素組成物
US9060927B2 (en) * 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
FR2943538B1 (fr) * 2009-03-27 2011-05-20 Adocia Formulation a action rapide d'insuline recombinante humaine
CA2805031A1 (en) 2010-07-07 2012-01-12 Biodel, Inc. Compositions and methods for modulating the pharmacokinetics and pharmacodynamics of insulin

Also Published As

Publication number Publication date
PT2838506T (pt) 2021-02-23
JP6422855B2 (ja) 2018-11-14
HK1207577A1 (en) 2016-02-05
HUE053303T2 (hu) 2021-06-28
JP2015512952A (ja) 2015-04-30
MX2014012245A (es) 2015-06-05
AU2013249495B2 (en) 2016-05-12
JP2019023223A (ja) 2019-02-14
US9381247B2 (en) 2016-07-05
DK2838506T3 (da) 2021-01-18
CY1123825T1 (el) 2022-05-27
EP2838506B1 (en) 2021-01-06
US20140113856A1 (en) 2014-04-24
SI2838506T1 (sl) 2021-02-26
PL2838506T3 (pl) 2021-06-28
EP2838506A1 (en) 2015-02-25
LT2838506T (lt) 2021-03-25
RU2014145846A (ru) 2016-06-10
WO2013158618A1 (en) 2013-10-24
KR101966484B1 (ko) 2019-04-05
IL234987A0 (en) 2014-12-31
ZA201407410B (en) 2015-06-24
EP3827813A1 (en) 2021-06-02
CN104394847A (zh) 2015-03-04
IN2014DN08417A (enExample) 2015-05-08
HK1203371A1 (en) 2015-10-30
RS61533B1 (sr) 2021-04-29
CA2869883A1 (en) 2013-10-24
ES2854874T3 (es) 2021-09-23
KR20140146209A (ko) 2014-12-24
SG11201406491PA (en) 2014-11-27

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