DK2838506T3 - Magnesiumsammensætninger til modulering af farmakokinetikken og farmakodynamikken af insulin og smerter på injektionsstedet - Google Patents

Magnesiumsammensætninger til modulering af farmakokinetikken og farmakodynamikken af insulin og smerter på injektionsstedet Download PDF

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Publication number
DK2838506T3
DK2838506T3 DK13721441.7T DK13721441T DK2838506T3 DK 2838506 T3 DK2838506 T3 DK 2838506T3 DK 13721441 T DK13721441 T DK 13721441T DK 2838506 T3 DK2838506 T3 DK 2838506T3
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Denmark
Prior art keywords
pharmacodynamics
pharmacokinetics
insulin
modulating
pain
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DK13721441.7T
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English (en)
Inventor
Roderike Pohl
Robert Hauser
Ming Li
Bryan R Wilson
Original Assignee
Lilly Co Eli
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Publication of DK2838506T3 publication Critical patent/DK2838506T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK13721441.7T 2012-04-16 2013-04-16 Magnesiumsammensætninger til modulering af farmakokinetikken og farmakodynamikken af insulin og smerter på injektionsstedet DK2838506T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261624844P 2012-04-16 2012-04-16
US201261704066P 2012-09-21 2012-09-21
US13/826,806 US9381247B2 (en) 2012-04-16 2013-03-14 Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin and insulin analogs, and injection site pain
PCT/US2013/036742 WO2013158618A1 (en) 2012-04-16 2013-04-16 Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin and insulin analogs, and injection site pain

Publications (1)

Publication Number Publication Date
DK2838506T3 true DK2838506T3 (da) 2021-01-18

Family

ID=48326401

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13721441.7T DK2838506T3 (da) 2012-04-16 2013-04-16 Magnesiumsammensætninger til modulering af farmakokinetikken og farmakodynamikken af insulin og smerter på injektionsstedet

Country Status (25)

Country Link
US (1) US9381247B2 (da)
EP (2) EP2838506B1 (da)
JP (2) JP6422855B2 (da)
KR (1) KR101966484B1 (da)
CN (1) CN104394847A (da)
AU (1) AU2013249495B2 (da)
CA (1) CA2869883A1 (da)
CY (1) CY1123825T1 (da)
DK (1) DK2838506T3 (da)
ES (1) ES2854874T3 (da)
HK (2) HK1203371A1 (da)
HR (1) HRP20210417T1 (da)
HU (1) HUE053303T2 (da)
IL (1) IL234987A0 (da)
IN (1) IN2014DN08417A (da)
LT (1) LT2838506T (da)
MX (1) MX2014012245A (da)
PL (1) PL2838506T3 (da)
PT (1) PT2838506T (da)
RS (1) RS61533B1 (da)
RU (1) RU2014145846A (da)
SG (1) SG11201406491PA (da)
SI (1) SI2838506T1 (da)
WO (1) WO2013158618A1 (da)
ZA (1) ZA201407410B (da)

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CN104902922B (zh) 2012-11-13 2017-12-12 阿道恰公司 包含经取代阴离子化合物的速效胰岛素制剂
CA2936563A1 (en) * 2014-01-13 2015-07-16 Thermalin Diabetes, Llc Rapid action insulin formulations and pharmaceutical delivery systems
WO2015120457A1 (en) * 2014-02-10 2015-08-13 Biodel Inc. Stabilized ultra-rapid-acting insulin formulations
TWI685348B (zh) * 2014-05-08 2020-02-21 美國禮來大藥廠 速效胰島素組合物
WO2016007935A2 (en) 2014-07-10 2016-01-14 Companion Medical, Inc. Medicine administering system including injection pen and companion device
AR102869A1 (es) 2014-12-16 2017-03-29 Lilly Co Eli Composiciones de insulina de rápida acción
AU2016209405A1 (en) * 2015-01-20 2017-08-24 Case Western Reserve University Insulin analogues with selective signaling properties and reduced mitogenicity
JO3749B1 (ar) * 2015-08-27 2021-01-31 Lilly Co Eli تركيبات إنسولين سريعة المفعول
WO2017132577A1 (en) 2016-01-29 2017-08-03 Companion Medical, Inc. Automatic medication delivery tracking
GB201607918D0 (en) 2016-05-06 2016-06-22 Arecor Ltd Novel formulations
GB201707189D0 (en) * 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
JOP20190277B1 (ar) 2017-06-01 2023-09-17 Lilly Co Eli تركيبات إنسولين سريعة المفعول
EP3635591A4 (en) 2017-06-09 2021-03-24 Companion Medical, Inc. SMART DRUG DELIVERY SYSTEMS AND PROCESSES
EP3694583A4 (en) * 2017-10-12 2021-08-04 Companion Medical, Inc. INTELLIGENT DRUG DELIVERY SYSTEMS AND METHODS FOR DOSAGE RECOMMENDATION AND ADMINISTRATION
US11116899B2 (en) 2017-12-12 2021-09-14 Bigfoot Biomedical, Inc. User interface for diabetes management systems and devices
US11464459B2 (en) 2017-12-12 2022-10-11 Bigfoot Biomedical, Inc. User interface for diabetes management systems including flash glucose monitor
US11090439B2 (en) 2017-12-12 2021-08-17 Bigfoot Biomedical, Inc. Therapy management systems, methods, and devices
US11077243B2 (en) 2017-12-12 2021-08-03 Bigfoot Biomedical, Inc. Devices, systems, and methods for estimating active medication from injections
US11083852B2 (en) 2017-12-12 2021-08-10 Bigfoot Biomedical, Inc. Insulin injection assistance systems, methods, and devices
US10987464B2 (en) 2017-12-12 2021-04-27 Bigfoot Biomedical, Inc. Pen cap for insulin injection pens and associated methods and systems
US10898653B2 (en) 2018-05-08 2021-01-26 Companion Medical, Inc. Intelligent medication delivery systems and methods for dose setting and dispensing monitoring
US11664107B2 (en) 2018-05-08 2023-05-30 Medtronic Minimed, Inc. Intelligent medication delivery systems and methods using a prescription-regulated software application
USD893020S1 (en) 2018-05-11 2020-08-11 Companion Medical, Inc. Injection pen
US11587663B2 (en) 2018-06-20 2023-02-21 Medtronic Minimed, Inc. Intelligent medication delivery systems and methods for medicine dose calculation and reporting
USD892819S1 (en) 2018-06-20 2020-08-11 Companion Medical, Inc. Display screen with graphical user interface
FR3083984A1 (fr) 2018-07-23 2020-01-24 Adocia Dispositif pour injecter une solution d'insuline(s)
WO2019243627A1 (fr) 2018-06-23 2019-12-26 Adocia Dispositif pour injecter une solution d'insuline(s)
FR3083985A1 (fr) 2018-07-23 2020-01-24 Adocia Dispositif pour injecter une solution d'insuline(s)
US11948671B2 (en) 2019-04-11 2024-04-02 Medtronic Minimed, Inc. Intelligent accessories for medicine dispensing device
US11701473B2 (en) 2021-06-23 2023-07-18 Medtronic Minimed, Inc. Reusable injection pens

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Also Published As

Publication number Publication date
JP2015512952A (ja) 2015-04-30
EP3827813A1 (en) 2021-06-02
CY1123825T1 (el) 2022-05-27
HRP20210417T1 (hr) 2021-04-30
EP2838506B1 (en) 2021-01-06
IL234987A0 (en) 2014-12-31
IN2014DN08417A (da) 2015-05-08
US20140113856A1 (en) 2014-04-24
CA2869883A1 (en) 2013-10-24
HK1207577A1 (en) 2016-02-05
SG11201406491PA (en) 2014-11-27
ES2854874T3 (es) 2021-09-23
US9381247B2 (en) 2016-07-05
RU2014145846A (ru) 2016-06-10
ZA201407410B (en) 2015-06-24
HUE053303T2 (hu) 2021-06-28
KR20140146209A (ko) 2014-12-24
WO2013158618A1 (en) 2013-10-24
PL2838506T3 (pl) 2021-06-28
HK1203371A1 (en) 2015-10-30
MX2014012245A (es) 2015-06-05
SI2838506T1 (sl) 2021-02-26
LT2838506T (lt) 2021-03-25
JP2019023223A (ja) 2019-02-14
KR101966484B1 (ko) 2019-04-05
JP6422855B2 (ja) 2018-11-14
RS61533B1 (sr) 2021-04-29
EP2838506A1 (en) 2015-02-25
CN104394847A (zh) 2015-03-04
PT2838506T (pt) 2021-02-23
AU2013249495B2 (en) 2016-05-12

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