HRP20201923T1 - Farmaceutske formulacije loratadina za kapsuliranje i njihove kombinacije - Google Patents
Farmaceutske formulacije loratadina za kapsuliranje i njihove kombinacije Download PDFInfo
- Publication number
- HRP20201923T1 HRP20201923T1 HRP20201923TT HRP20201923T HRP20201923T1 HR P20201923 T1 HRP20201923 T1 HR P20201923T1 HR P20201923T T HRP20201923T T HR P20201923TT HR P20201923 T HRP20201923 T HR P20201923T HR P20201923 T1 HRP20201923 T1 HR P20201923T1
- Authority
- HR
- Croatia
- Prior art keywords
- amount
- fatty acids
- formulation
- medium
- weight
- Prior art date
Links
- 229960003088 loratadine Drugs 0.000 title claims 4
- JCCNYMKQOSZNPW-UHFFFAOYSA-N loratadine Chemical compound C1CN(C(=O)OCC)CCC1=C1C2=NC=CC=C2CCC2=CC(Cl)=CC=C21 JCCNYMKQOSZNPW-UHFFFAOYSA-N 0.000 title claims 4
- 238000005538 encapsulation Methods 0.000 title claims 2
- 239000008194 pharmaceutical composition Substances 0.000 title claims 2
- 238000009472 formulation Methods 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 8
- 235000014113 dietary fatty acids Nutrition 0.000 claims 6
- 229930195729 fatty acid Natural products 0.000 claims 6
- 239000000194 fatty acid Substances 0.000 claims 6
- 239000004094 surface-active agent Substances 0.000 claims 4
- -1 triglyceride fatty acids Chemical class 0.000 claims 4
- 239000002775 capsule Substances 0.000 claims 3
- 239000002552 dosage form Substances 0.000 claims 3
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical group C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 2
- 239000002270 dispersing agent Substances 0.000 claims 2
- 238000012377 drug delivery Methods 0.000 claims 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 2
- 229940069328 povidone Drugs 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- YOYOQXRPUDEPAK-UHFFFAOYSA-N 1-Hydroxy-3-(octanoyloxy)propan-2-yl decanoate Chemical compound CCCCCCCCCC(=O)OC(CO)COC(=O)CCCCCCC YOYOQXRPUDEPAK-UHFFFAOYSA-N 0.000 claims 1
- 108010010803 Gelatin Proteins 0.000 claims 1
- 229920001214 Polysorbate 60 Polymers 0.000 claims 1
- 229920003078 Povidone K 12 Polymers 0.000 claims 1
- CJPQIRJHIZUAQP-MRXNPFEDSA-N benalaxyl-M Chemical compound CC=1C=CC=C(C)C=1N([C@H](C)C(=O)OC)C(=O)CC1=CC=CC=C1 CJPQIRJHIZUAQP-MRXNPFEDSA-N 0.000 claims 1
- GHVNFZFCNZKVNT-UHFFFAOYSA-M decanoate Chemical compound CCCCCCCCCC([O-])=O GHVNFZFCNZKVNT-UHFFFAOYSA-M 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 229920000159 gelatin Polymers 0.000 claims 1
- 239000008273 gelatin Substances 0.000 claims 1
- 239000007903 gelatin capsule Substances 0.000 claims 1
- 235000019322 gelatine Nutrition 0.000 claims 1
- 235000011852 gelatine desserts Nutrition 0.000 claims 1
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000012669 liquid formulation Substances 0.000 claims 1
- 150000004667 medium chain fatty acids Chemical class 0.000 claims 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims 1
- 229920000053 polysorbate 80 Polymers 0.000 claims 1
- 229940068968 polysorbate 80 Drugs 0.000 claims 1
- 150000003626 triacylglycerols Chemical class 0.000 claims 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 1
- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2690490A CA2690490C (en) | 2010-01-19 | 2010-01-19 | Pharmaceutical formulations of loratadine for encapsulation and combinations thereof |
| PCT/CA2011/000052 WO2011088550A1 (en) | 2010-01-19 | 2011-01-18 | Pharmaceutical formulations of loratadine for encapsulation and combinations thereof |
| EP11734280.8A EP2525827B1 (en) | 2010-01-19 | 2011-01-18 | Pharmaceutical formulations of loratadine for encapsulation and combinations thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20201923T1 true HRP20201923T1 (hr) | 2021-02-05 |
Family
ID=44303619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20201923TT HRP20201923T1 (hr) | 2010-01-19 | 2020-12-02 | Farmaceutske formulacije loratadina za kapsuliranje i njihove kombinacije |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20120301544A1 (pt) |
| EP (2) | EP2525827B1 (pt) |
| JP (1) | JP5328992B2 (pt) |
| AU (1) | AU2011207058B2 (pt) |
| CA (1) | CA2690490C (pt) |
| CY (1) | CY1123895T1 (pt) |
| DK (1) | DK2525827T3 (pt) |
| ES (1) | ES2843351T3 (pt) |
| HR (1) | HRP20201923T1 (pt) |
| HU (1) | HUE053412T2 (pt) |
| LT (1) | LT2525827T (pt) |
| MX (1) | MX344163B (pt) |
| PL (1) | PL2525827T3 (pt) |
| PT (1) | PT2525827T (pt) |
| RS (1) | RS61362B1 (pt) |
| SI (1) | SI2525827T1 (pt) |
| WO (1) | WO2011088550A1 (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784399B (zh) * | 2014-03-05 | 2015-09-30 | 大连金石滩药业有限公司 | 氯雷他定液体组合物 |
| CN103784446B (zh) * | 2014-03-05 | 2016-01-06 | 大连金石滩药业有限公司 | 氯雷他定组合物 |
| JP7065562B2 (ja) * | 2015-09-04 | 2022-05-12 | ロート製薬株式会社 | 医薬組成物 |
| KR101746500B1 (ko) | 2016-05-26 | 2017-06-14 | (주)알피바이오 | 연질캡슐 제제용 로라타딘 조성물 및 이를 함유하는 연질캡슐 |
| US11607384B2 (en) | 2017-12-08 | 2023-03-21 | Western University Of Health Sciences | Lipid emulsified drug delivery systems for chemoprevention and treatment |
| CA3100314A1 (en) | 2018-05-16 | 2019-11-21 | Bayer Healthcare Llc | High concentration suspension formulation for cold and flu soft gel capsule medications |
| CN112426404B (zh) * | 2020-10-29 | 2023-02-28 | 太阳升(亳州)生物医药科技有限公司 | 用于制备富马酸卢帕他定口服液的方法 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4282233B1 (en) | 1980-06-19 | 2000-09-05 | Schering Corp | Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines |
| WO1985003707A1 (en) | 1984-02-15 | 1985-08-29 | Schering Corporation | 8-CHLORO-6,11-DIHYDRO-11-(4-PIPERIDYLIDENE)-5H-BENZO AD5,6 BDCYCLOHEPTA AD1,2-b BDPYRIDINE AND ITS SALTS, PROCESSES FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS |
| GB8903804D0 (en) * | 1989-02-20 | 1989-04-05 | Sandoz Ltd | Improvements in or relating to organic compounds |
| US4900775A (en) * | 1988-02-29 | 1990-02-13 | Gaf Chemicals Corporation | Solubilization of complexes of water-insoluble organic compounds by aqueous solutions of polyvinylpyrrolidone |
| US4910205A (en) | 1988-05-02 | 1990-03-20 | Schering Corporation | Transdermal delivery of loratadine |
| US4863931A (en) | 1988-09-15 | 1989-09-05 | Schering Corporation | Antihistaminic fluoro substituted benzocycloheptapyridines |
| US4990535A (en) | 1989-05-03 | 1991-02-05 | Schering Corporation | Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine |
| IL102633A0 (en) * | 1991-07-26 | 1993-01-14 | Smithkline Beecham Corp | Compositions |
| US5314697A (en) | 1992-10-23 | 1994-05-24 | Schering Corporation | Stable extended release oral dosage composition comprising loratadine and pseudoephedrine |
| GB9226238D0 (en) | 1992-12-16 | 1993-02-10 | Scherer Ltd R P | Encapsulation apparatus and process |
| US6054136A (en) * | 1993-09-30 | 2000-04-25 | Gattefosse S.A. | Orally administrable composition capable of providing enhanced bioavailability when ingested |
| CN1138827A (zh) * | 1994-01-24 | 1996-12-25 | 普罗克特和甘保尔公司 | 使难溶药物活性物增溶的方法 |
| GB9405304D0 (en) * | 1994-03-16 | 1994-04-27 | Scherer Ltd R P | Delivery systems for hydrophobic drugs |
| NZ284068A (en) * | 1994-04-07 | 1998-06-26 | Smithkline Beecham Plc | Medicament comprising halofantrine free base |
| US5595997A (en) | 1994-12-30 | 1997-01-21 | Sepracor Inc. | Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine |
| CA2318128C (en) * | 1998-01-20 | 2008-10-14 | Applied Analytical Industries, Inc. | Oral liquid compositions |
| US6132758A (en) | 1998-06-01 | 2000-10-17 | Schering Corporation | Stabilized antihistamine syrup |
| DK0968715T3 (da) | 1998-06-30 | 2004-12-27 | Pfizer Prod Inc | Loratadin til anvendelse som et antiarytmikum |
| US6221391B1 (en) * | 1998-11-23 | 2001-04-24 | Accucaps Industries Limited | Self-emulsifying ibuprofen solution and soft gelatin capsule for use therewith |
| US20030235595A1 (en) * | 1999-06-30 | 2003-12-25 | Feng-Jing Chen | Oil-containing, orally administrable pharmaceutical composition for improved delivery of a therapeutic agent |
| US7115565B2 (en) * | 2001-01-18 | 2006-10-03 | Pharmacia & Upjohn Company | Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability |
| US6720002B2 (en) * | 2001-07-20 | 2004-04-13 | R.P. Scherer Technologies, Inc. | Antihistamine formulations for soft capsule dosage forms |
| ES2294197T3 (es) * | 2001-12-21 | 2008-04-01 | Supernus Pharmaceuticals, Inc. | Formulacion de capsula oral con estabilidad fisica aumentada. |
| US20040033257A1 (en) * | 2002-05-30 | 2004-02-19 | Strides Inc. | Pharmaceutical formulation in a drug delivery system and process for preparing the same |
| KR100533460B1 (ko) * | 2002-07-20 | 2005-12-08 | 대화제약 주식회사 | 난용성 약물의 가용화용 점막흡착성 조성물, 이를 이용한난용성 약물의 가용화용 제형 및 이들의 제조 방법 |
| WO2006104703A1 (en) * | 2005-03-29 | 2006-10-05 | Mcneil-Ppc, Inc. | Compositions with hydrophilic drugs in a hydrophobic medium |
| WO2009066146A2 (en) * | 2007-11-19 | 2009-05-28 | Cadila Pharmaceuticals Ltd. | Stable solutions of sparingly soluble actives |
-
2010
- 2010-01-19 CA CA2690490A patent/CA2690490C/en active Active
-
2011
- 2011-01-18 EP EP11734280.8A patent/EP2525827B1/en active Active
- 2011-01-18 PL PL11734280T patent/PL2525827T3/pl unknown
- 2011-01-18 WO PCT/CA2011/000052 patent/WO2011088550A1/en active Application Filing
- 2011-01-18 DK DK11734280.8T patent/DK2525827T3/da active
- 2011-01-18 EP EP19217776.4A patent/EP3653204A1/en active Pending
- 2011-01-18 US US13/574,189 patent/US20120301544A1/en active Pending
- 2011-01-18 LT LTEP11734280.8T patent/LT2525827T/lt unknown
- 2011-01-18 SI SI201131943T patent/SI2525827T1/sl unknown
- 2011-01-18 ES ES11734280T patent/ES2843351T3/es active Active
- 2011-01-18 AU AU2011207058A patent/AU2011207058B2/en active Active
- 2011-01-18 PT PT117342808T patent/PT2525827T/pt unknown
- 2011-01-18 JP JP2012549213A patent/JP5328992B2/ja not_active Expired - Fee Related
- 2011-01-18 RS RS20210013A patent/RS61362B1/sr unknown
- 2011-01-18 MX MX2012008301A patent/MX344163B/es active IP Right Grant
- 2011-01-18 HU HUE11734280A patent/HUE053412T2/hu unknown
-
2020
- 2020-12-02 HR HRP20201923TT patent/HRP20201923T1/hr unknown
-
2021
- 2021-01-13 CY CY20211100020T patent/CY1123895T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2011207058A1 (en) | 2012-09-06 |
| EP2525827A4 (en) | 2014-04-30 |
| SI2525827T1 (sl) | 2021-02-26 |
| CA2690490A1 (en) | 2011-07-19 |
| JP2013517303A (ja) | 2013-05-16 |
| EP2525827B1 (en) | 2020-11-18 |
| EP2525827A1 (en) | 2012-11-28 |
| RS61362B1 (sr) | 2021-02-26 |
| US20120301544A1 (en) | 2012-11-29 |
| PL2525827T3 (pl) | 2021-05-04 |
| MX344163B (es) | 2016-12-07 |
| MX2012008301A (es) | 2012-09-28 |
| JP5328992B2 (ja) | 2013-10-30 |
| CA2690490C (en) | 2012-06-26 |
| PT2525827T (pt) | 2021-01-20 |
| AU2011207058B2 (en) | 2015-04-23 |
| EP3653204A1 (en) | 2020-05-20 |
| CY1123895T1 (el) | 2022-05-27 |
| ES2843351T3 (es) | 2021-07-16 |
| HUE053412T2 (hu) | 2021-06-28 |
| LT2525827T (lt) | 2021-03-25 |
| WO2011088550A1 (en) | 2011-07-28 |
| DK2525827T3 (da) | 2020-12-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20201923T1 (hr) | Farmaceutske formulacije loratadina za kapsuliranje i njihove kombinacije | |
| KR102275447B1 (ko) | ω3 지방산의 자기 유화 조성물 | |
| ES2817527T3 (es) | Composición autoemulsionante de ácidos grasos omega-3 | |
| JP6835664B2 (ja) | 脂肪酸油混合物の被覆型カプセル剤および錠剤 | |
| KR102488648B1 (ko) | ω3 지방산의 자기 유화 조성물 | |
| JP6151314B2 (ja) | ω３脂肪酸の自己乳化組成物 | |
| HRP20160446T1 (hr) | Farmaceutski pripravci koji sadrže derivat kamptotecina | |
| JP2015520235A5 (pt) | ||
| NZ600720A (en) | A Seamless Capsule For A Liquid Pharmaceutical Composition | |
| JP2013508296A5 (pt) | ||
| HRP20171431T1 (hr) | Terapijska parenteralna primjena krilovog ulja | |
| WO2010117873A3 (en) | Progesterone solutions for increased bioavailability | |
| JP5820256B2 (ja) | 自己乳化製剤 | |
| MX2019013095A (es) | Formulaciones farmaceuticas de estatinas y acidos grasos omega-3 para encapsulacion. | |
| JP2013508348A5 (pt) | ||
| JP6282645B2 (ja) | ラセカドトリル脂質組成物 | |
| RU2011139638A (ru) | Сублингвальная фармацевтическая композиция, содержащая нейтральное масло | |
| JP2015516418A5 (pt) | ||
| AU2016324349A1 (en) | Ubiquinone and ubiquinol compositions, and methods relating thereto | |
| JP2016512828A (ja) | ラセカドトリル脂質組成物 | |
| RU2010120706A (ru) | Композиция липоевой кислоты в виде шариков | |
| JP2011006380A (ja) | ω３脂肪酸の乳化組成物 | |
| AR084235A1 (es) | Composiciones farmaceuticas que comprenden alisporivir | |
| JP2014513710A5 (pt) | ||
| ES2944572T3 (es) | Procedimiento de tratamiento de la obesidad |