MX344163B - Formulaciones farmacéuticas de loratadina para encapsulación y combinaciones de las mismas. - Google Patents

Formulaciones farmacéuticas de loratadina para encapsulación y combinaciones de las mismas.

Info

Publication number
MX344163B
MX344163B MX2012008301A MX2012008301A MX344163B MX 344163 B MX344163 B MX 344163B MX 2012008301 A MX2012008301 A MX 2012008301A MX 2012008301 A MX2012008301 A MX 2012008301A MX 344163 B MX344163 B MX 344163B
Authority
MX
Mexico
Prior art keywords
loratadine
formulation
encapsulation
combinations
dosage unit
Prior art date
Application number
MX2012008301A
Other languages
English (en)
Other versions
MX2012008301A (es
Inventor
Draper Peter
Okutan Beth
Draper James
Original Assignee
Accucaps Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Accucaps Ind Ltd filed Critical Accucaps Ind Ltd
Publication of MX2012008301A publication Critical patent/MX2012008301A/es
Publication of MX344163B publication Critical patent/MX344163B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Esta invención se relaciona a una formulación de loratadina adecuada para la encapsulación en una cápsula de gel blando o unidad de dosificación adecuada con funcionalidad mejorada que proporciona disolución y biodisponibilidad in vitro aumentada de loratadina. La invención también proporciona una formulación con funcionalidad mejorada como una solución altamente concentrada dentro de un volumen de llenado dado con el fin de fabricar una cápsula tan pequeña como sea posible para facilitar la aceptación del consumidor y costos de fabricación aceptables. La invención también se relaciona a una formulación de estabilidad óptima adecuada para soportar una composición de llenado compatible con la unidad de dosificación de cápsula de gel blando.
MX2012008301A 2010-01-19 2011-01-18 Formulaciones farmacéuticas de loratadina para encapsulación y combinaciones de las mismas. MX344163B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA2690490A CA2690490C (en) 2010-01-19 2010-01-19 Pharmaceutical formulations of loratadine for encapsulation and combinations thereof
PCT/CA2011/000052 WO2011088550A1 (en) 2010-01-19 2011-01-18 Pharmaceutical formulations of loratadine for encapsulation and combinations thereof

Publications (2)

Publication Number Publication Date
MX2012008301A MX2012008301A (es) 2012-09-28
MX344163B true MX344163B (es) 2016-12-07

Family

ID=44303619

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012008301A MX344163B (es) 2010-01-19 2011-01-18 Formulaciones farmacéuticas de loratadina para encapsulación y combinaciones de las mismas.

Country Status (17)

Country Link
US (1) US20120301544A1 (es)
EP (2) EP3653204A1 (es)
JP (1) JP5328992B2 (es)
AU (1) AU2011207058B2 (es)
CA (1) CA2690490C (es)
CY (1) CY1123895T1 (es)
DK (1) DK2525827T3 (es)
ES (1) ES2843351T3 (es)
HR (1) HRP20201923T1 (es)
HU (1) HUE053412T2 (es)
LT (1) LT2525827T (es)
MX (1) MX344163B (es)
PL (1) PL2525827T3 (es)
PT (1) PT2525827T (es)
RS (1) RS61362B1 (es)
SI (1) SI2525827T1 (es)
WO (1) WO2011088550A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103784446B (zh) * 2014-03-05 2016-01-06 大连金石滩药业有限公司 氯雷他定组合物
CN103784399B (zh) * 2014-03-05 2015-09-30 大连金石滩药业有限公司 氯雷他定液体组合物
JP7065562B2 (ja) * 2015-09-04 2022-05-12 ロート製薬株式会社 医薬組成物
KR101746500B1 (ko) 2016-05-26 2017-06-14 (주)알피바이오 연질캡슐 제제용 로라타딘 조성물 및 이를 함유하는 연질캡슐
WO2019113461A1 (en) 2017-12-08 2019-06-13 Western University Of Health Sciences Lipid emulsified drug delivery systems for chemoprevention and treatment
MX2020012233A (es) 2018-05-16 2021-01-29 Bayer Healthcare Llc Formula de suspension de alta concentracion para medicamentos en capsula de gel blanda para resfriado y gripe.
CN112426404B (zh) * 2020-10-29 2023-02-28 太阳升(亳州)生物医药科技有限公司 用于制备富马酸卢帕他定口服液的方法

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US4282233B1 (en) 1980-06-19 2000-09-05 Schering Corp Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines
AU570306B2 (en) 1984-02-15 1988-03-10 Schering Corporation 8-chloro-6, 11-dihydro-11-(4-piperidylidene)-5h-benzo (5,6) cyclohepta (1,2-b) pyridine and its salts.
GB8903804D0 (en) * 1989-02-20 1989-04-05 Sandoz Ltd Improvements in or relating to organic compounds
US4910205A (en) 1988-05-02 1990-03-20 Schering Corporation Transdermal delivery of loratadine
US4863931A (en) 1988-09-15 1989-09-05 Schering Corporation Antihistaminic fluoro substituted benzocycloheptapyridines
US4990535A (en) 1989-05-03 1991-02-05 Schering Corporation Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine
AU667316B2 (en) * 1991-07-26 1996-03-21 Smithkline Beecham Corporation W/O microemulsions
US5314697A (en) 1992-10-23 1994-05-24 Schering Corporation Stable extended release oral dosage composition comprising loratadine and pseudoephedrine
GB9226238D0 (en) 1992-12-16 1993-02-10 Scherer Ltd R P Encapsulation apparatus and process
US6054136A (en) * 1993-09-30 2000-04-25 Gattefosse S.A. Orally administrable composition capable of providing enhanced bioavailability when ingested
CA2181241C (en) * 1994-01-24 2000-04-25 Dadi Jamshed Dhabhar Process for solubilizing difficultly soluble pharmaceutical actives
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
DE69525740T2 (de) * 1994-04-07 2002-10-24 Smithkline Beecham Plc Spezielle halofantrinhaltige Zusammensetzungen
US5595997A (en) 1994-12-30 1997-01-21 Sepracor Inc. Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine
WO1999036060A1 (en) * 1998-01-20 1999-07-22 Applied Analytical Industries, Inc. Oral liquid compositions
US6132758A (en) 1998-06-01 2000-10-17 Schering Corporation Stabilized antihistamine syrup
ES2226289T3 (es) 1998-06-30 2005-03-16 Pfizer Products Inc. Loratadina para uso como antiarritmico.
US6221391B1 (en) * 1998-11-23 2001-04-24 Accucaps Industries Limited Self-emulsifying ibuprofen solution and soft gelatin capsule for use therewith
US20030235595A1 (en) * 1999-06-30 2003-12-25 Feng-Jing Chen Oil-containing, orally administrable pharmaceutical composition for improved delivery of a therapeutic agent
US6720002B2 (en) * 2001-07-20 2004-04-13 R.P. Scherer Technologies, Inc. Antihistamine formulations for soft capsule dosage forms
CA2466868C (en) * 2001-12-21 2010-06-22 Shire Laboratories Inc. Oral capsule formulation with increased physical stability
US20040033257A1 (en) * 2002-05-30 2004-02-19 Strides Inc. Pharmaceutical formulation in a drug delivery system and process for preparing the same
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Also Published As

Publication number Publication date
PL2525827T3 (pl) 2021-05-04
LT2525827T (lt) 2021-03-25
ES2843351T3 (es) 2021-07-16
HUE053412T2 (hu) 2021-06-28
DK2525827T3 (da) 2020-12-14
WO2011088550A1 (en) 2011-07-28
HRP20201923T1 (hr) 2021-02-05
EP2525827A4 (en) 2014-04-30
MX2012008301A (es) 2012-09-28
CY1123895T1 (el) 2022-05-27
JP2013517303A (ja) 2013-05-16
EP2525827B1 (en) 2020-11-18
RS61362B1 (sr) 2021-02-26
SI2525827T1 (sl) 2021-02-26
JP5328992B2 (ja) 2013-10-30
CA2690490A1 (en) 2011-07-19
CA2690490C (en) 2012-06-26
AU2011207058B2 (en) 2015-04-23
PT2525827T (pt) 2021-01-20
AU2011207058A1 (en) 2012-09-06
EP3653204A1 (en) 2020-05-20
US20120301544A1 (en) 2012-11-29
EP2525827A1 (en) 2012-11-28

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