HRP20191607T1 - Biomarkeri za inaktivaciju kolateralnih gena i ciljevi za terapiju raka - Google Patents

Biomarkeri za inaktivaciju kolateralnih gena i ciljevi za terapiju raka Download PDF

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Publication number
HRP20191607T1
HRP20191607T1 HRP20191607T HRP20191607T1 HR P20191607 T1 HRP20191607 T1 HR P20191607T1 HR P20191607 T HRP20191607 T HR P20191607T HR P20191607 T1 HRP20191607 T1 HR P20191607T1
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HR
Croatia
Prior art keywords
redundant
homolog
host gene
redundant homolog
cancer
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English (en)
Croatian (hr)
Inventor
Florian L Muller
Eliot Fletcher-Sananikone
Simona Colla
Elisa Aquilanti
Ronald Depinho
Original Assignee
Univ Texas
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Univ Texas, Dana Farber Cancer Inst Inc filed Critical Univ Texas
Publication of HRP20191607T1 publication Critical patent/HRP20191607T1/hr

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    • A—HUMAN NECESSITIES
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
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    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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HRP20191607 2011-12-14 2012-12-14 Biomarkeri za inaktivaciju kolateralnih gena i ciljevi za terapiju raka HRP20191607T1 (hr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161570366P 2011-12-14 2011-12-14
US201261652738P 2012-05-29 2012-05-29
PCT/US2012/069767 WO2013090732A2 (en) 2011-12-14 2012-12-14 Collateral gene inactivation biomarkers and targets for cancer therapy
EP12858619.5A EP2790738B1 (en) 2011-12-14 2012-12-14 Collateral gene inactivation biomarkers and targets for cancer therapy

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HRP20191607T1 true HRP20191607T1 (hr) 2019-12-13

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HRP20191607 HRP20191607T1 (hr) 2011-12-14 2012-12-14 Biomarkeri za inaktivaciju kolateralnih gena i ciljevi za terapiju raka

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US (1) US9452182B2 (show.php)
EP (2) EP3603678A3 (show.php)
JP (2) JP6820653B2 (show.php)
KR (2) KR102144452B1 (show.php)
CN (3) CN109276717B (show.php)
DK (1) DK2790738T3 (show.php)
ES (1) ES2746058T3 (show.php)
HR (1) HRP20191607T1 (show.php)
HU (1) HUE045359T2 (show.php)
IN (1) IN2014DN05803A (show.php)
WO (1) WO2013090732A2 (show.php)

Families Citing this family (20)

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Publication number Priority date Publication date Assignee Title
EP3094341B1 (en) 2014-01-13 2019-10-02 Berg LLC Enolase 1 (eno1) compositions and uses thereof
CN104894229A (zh) * 2014-03-04 2015-09-09 中南大学 己糖激酶2作为鼻咽癌放疗预后预测的生物标志物
EP3240566B1 (en) * 2014-12-31 2020-07-22 Development Center for Biotechnology Humanized alpha-enolase specific antibodies and methods of uses in cancer therapy
PT3268376T (pt) 2015-03-09 2022-04-08 Univ Texas Inibidores de enolase e métodos de tratamento com os mesmos
WO2017074788A1 (en) * 2015-10-27 2017-05-04 The Broad Institute Inc. Compositions and methods for targeting cancer-specific sequence variations
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