HRP20191523T1 - Paraziticidne kombinacije spirocikličkog izoksazolina - Google Patents
Paraziticidne kombinacije spirocikličkog izoksazolina Download PDFInfo
- Publication number
- HRP20191523T1 HRP20191523T1 HRP20191523T HRP20191523T1 HR P20191523 T1 HRP20191523 T1 HR P20191523T1 HR P20191523 T HRP20191523 T HR P20191523T HR P20191523 T1 HRP20191523 T1 HR P20191523T1
- Authority
- HR
- Croatia
- Prior art keywords
- preparation
- intended
- animal
- spirocyclic isoxazoline
- parasiticidal
- Prior art date
Links
- WEQPBCSPRXFQQS-UHFFFAOYSA-N 4,5-dihydro-1,2-oxazole Chemical compound C1CC=NO1 WEQPBCSPRXFQQS-UHFFFAOYSA-N 0.000 title 1
- 230000000590 parasiticidal effect Effects 0.000 title 1
- 208000030852 Parasitic disease Diseases 0.000 claims 2
- AQXXZDYPVDOQEE-MXDQRGINSA-N Pyrantel pamoate Chemical compound CN1CCCN=C1\C=C\C1=CC=CS1.C1=CC=C2C(CC=3C4=CC=CC=C4C=C(C=3O)C(=O)O)=C(O)C(C(O)=O)=CC2=C1 AQXXZDYPVDOQEE-MXDQRGINSA-N 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 244000144972 livestock Species 0.000 claims 1
- YZBLFMPOMVTDJY-CBYMMZEQSA-N moxidectin Chemical compound O1[C@H](C(\C)=C\C(C)C)[C@@H](C)C(=N/OC)\C[C@@]11O[C@H](C\C=C(C)\C[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 YZBLFMPOMVTDJY-CBYMMZEQSA-N 0.000 claims 1
- 229960004816 moxidectin Drugs 0.000 claims 1
- 229960000996 pyrantel pamoate Drugs 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
- A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
- A01N37/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/60—1,4-Diazines; Hydrogenated 1,4-diazines
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/18—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/34—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the groups, e.g. biuret; Thio analogues thereof; Urea-aldehyde condensation products
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N51/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds having the sequences of atoms O—N—S, X—O—S, N—N—S, O—N—N or O-halogen, regardless of the number of bonds each atom has and with no atom of these sequences forming part of a heterocyclic ring
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Claims (6)
1. Pripravak, naznačen time što sadrži a) S-izomer spoja Formule (1.1),
,
ili njegovu farmaceutski ili veterinarski prihvatljivu sol; b) moksidektin i c) pirantel-pamoat.
2. Pripravak u skladu s patentnim zahtjevom 1, naznačen time što je namijenjen upotrebi u liječenju parazitne infekcije kod životinje kojoj je to potrebno.
3. Pripravak namijenjen upotrebi u skladu s patentnim zahtjevom 2, naznačen time što je primjena oralna, topikalna, ili injekcijom.
4. Pripravak namijenjen upotrebi u skladu s patentnim zahtjevom 3, naznačen time što je životinja kućna životinja ili stoka.
5. Pripravak u skladu s patentnim zahtjevom 1, naznačen time što dodatno sadrži veterinarski ili farmaceutski prihvatljivu podlogu.
6. Pripravak u skladu s patentnim zahtjevom 5, naznačen time što je namijenjen upotrebi u liječenju parazitne infekcije kod životinje kojoj je to potrebno.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261698116P | 2012-09-07 | 2012-09-07 | |
PCT/US2013/057925 WO2014039475A1 (en) | 2012-09-07 | 2013-09-04 | Spirocyclic isoxazoline parasiticidal combinations |
EP13765847.2A EP2892347B1 (en) | 2012-09-07 | 2013-09-04 | Spirocyclic isoxazoline parasiticidal combinations |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20191523T1 true HRP20191523T1 (hr) | 2019-11-29 |
Family
ID=49226519
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20191523 HRP20191523T1 (hr) | 2012-09-07 | 2019-08-22 | Paraziticidne kombinacije spirocikličkog izoksazolina |
Country Status (25)
Country | Link |
---|---|
US (1) | US9226928B2 (hr) |
EP (1) | EP2892347B1 (hr) |
JP (1) | JP5978478B2 (hr) |
KR (1) | KR101792370B1 (hr) |
CN (1) | CN104602529B (hr) |
AU (1) | AU2013312882B2 (hr) |
BR (1) | BR112015004698B8 (hr) |
CA (1) | CA2882200C (hr) |
DK (1) | DK2892347T3 (hr) |
ES (1) | ES2748631T3 (hr) |
FI (1) | FIC20200007I1 (hr) |
HR (1) | HRP20191523T1 (hr) |
HU (2) | HUE045577T2 (hr) |
LT (2) | LT2892347T (hr) |
LU (1) | LUC00146I2 (hr) |
MX (1) | MX355843B (hr) |
NL (1) | NL301030I2 (hr) |
NO (1) | NO2020002I1 (hr) |
NZ (1) | NZ704627A (hr) |
PL (1) | PL2892347T3 (hr) |
PT (1) | PT2892347T (hr) |
RS (1) | RS59297B1 (hr) |
SI (1) | SI2892347T1 (hr) |
WO (1) | WO2014039475A1 (hr) |
ZA (1) | ZA201501226B (hr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2013312896A1 (en) * | 2012-09-07 | 2015-02-26 | Zoetis Services Llc | Spirocyclic derivatives as antiparasitic agents |
AR096346A1 (es) * | 2013-05-20 | 2015-12-23 | Zoetis Llc | Composiciones antiparasitarias de espiro-isoxazolina de acción prolongada |
GB2551214B (en) * | 2015-01-16 | 2019-06-12 | Avista Pharma Solutions | Antiparasitic compounds |
UY36570A (es) * | 2015-02-26 | 2016-10-31 | Merial Inc | Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas |
NZ736374A (en) * | 2015-04-08 | 2024-02-23 | Boehringer Ingelheim Vetmedica Gmbh | Extended release injectable formulations comprising an isoxazoline active agent, methods and uses thereof |
UY37137A (es) | 2016-02-24 | 2017-09-29 | Merial Inc | Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos |
WO2017201134A1 (en) * | 2016-05-20 | 2017-11-23 | Avista Pharma Solutions, Inc. | Synthetic process and novel intermediates |
WO2018039508A1 (en) | 2016-08-25 | 2018-03-01 | Merial, Inc. | Method for reducing unwanted effects in parasiticidal treatments |
US10653144B2 (en) | 2016-10-14 | 2020-05-19 | Boehringer Ingelheim Animal Health USA Inc. | Pesticidal and parasiticidal vinyl isoxazoline compounds |
BR112020003217A2 (pt) | 2017-08-14 | 2020-10-06 | Boehringer Ingelheim Animal Health USA Inc. | compostos pesticidas e parasiticidas de pirazolisoxazolina |
AU2019336663B2 (en) * | 2018-09-05 | 2023-09-14 | Zoetis Services Llc | Palatable antiparasitic formulations |
SI3815677T1 (sl) * | 2019-10-30 | 2023-12-29 | Krka, D.D., Novo Mesto | Stabilni veterinarski sestavek, ki obsega moksidektin in imidakloprid |
MX2022014493A (es) | 2020-05-20 | 2022-12-13 | Intervet Int Bv | Composiciones farmaceuticas inyectables y usos de las mismas. |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0721629B1 (pt) * | 2007-05-03 | 2019-03-19 | Merial, Inc. | Composições compreendendo compostos macrolídeos com éter de alquila em c-13 e compostos de fenilpirazol |
CA2807005C (en) | 2010-08-05 | 2015-04-07 | Ah Usa 42 Llc | Isoxazoline derivatives as antiparasitic agents |
JP2014015397A (ja) | 2010-11-04 | 2014-01-30 | Nippon Soda Co Ltd | 動物用外部寄生虫防除剤 |
RU2566083C3 (ru) * | 2011-03-10 | 2017-11-09 | Зоетис Сервисиз ЛЛК | Спироциклические производные изоксазолина в качестве противопаразитарных агентов |
NZ704175A (en) * | 2012-08-31 | 2015-10-30 | Zoetis Services Llc | Crystalline forms of 1-(5’-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3’h-spiro[azetidine-3,1’-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone |
CA2882199A1 (en) * | 2012-09-04 | 2014-03-13 | Zoetis Llc | Spirocyclic isoxazoline derivatives for treatment of sea lice |
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2013
- 2013-09-04 NZ NZ704627A patent/NZ704627A/en unknown
- 2013-09-04 EP EP13765847.2A patent/EP2892347B1/en active Active
- 2013-09-04 WO PCT/US2013/057925 patent/WO2014039475A1/en active Application Filing
- 2013-09-04 DK DK13765847.2T patent/DK2892347T3/da active
- 2013-09-04 MX MX2015003005A patent/MX355843B/es active IP Right Grant
- 2013-09-04 PT PT137658472T patent/PT2892347T/pt unknown
- 2013-09-04 KR KR1020157005936A patent/KR101792370B1/ko active IP Right Grant
- 2013-09-04 US US14/426,264 patent/US9226928B2/en active Active
- 2013-09-04 RS RSP20191173 patent/RS59297B1/sr unknown
- 2013-09-04 HU HUE13765847A patent/HUE045577T2/hu unknown
- 2013-09-04 BR BR112015004698A patent/BR112015004698B8/pt active IP Right Grant
- 2013-09-04 ES ES13765847T patent/ES2748631T3/es active Active
- 2013-09-04 CN CN201380046586.9A patent/CN104602529B/zh active Active
- 2013-09-04 LT LT13765847T patent/LT2892347T/lt unknown
- 2013-09-04 SI SI201331571T patent/SI2892347T1/sl unknown
- 2013-09-04 CA CA2882200A patent/CA2882200C/en active Active
- 2013-09-04 PL PL13765847T patent/PL2892347T3/pl unknown
- 2013-09-04 JP JP2015531153A patent/JP5978478B2/ja active Active
- 2013-09-04 AU AU2013312882A patent/AU2013312882B2/en active Active
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2015
- 2015-02-23 ZA ZA2015/01226A patent/ZA201501226B/en unknown
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2019
- 2019-08-22 HR HRP20191523 patent/HRP20191523T1/hr unknown
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2020
- 2020-01-27 NL NL301030C patent/NL301030I2/nl unknown
- 2020-02-03 HU HUS2000004C patent/HUS2000004I1/hu unknown
- 2020-02-05 LU LU00146C patent/LUC00146I2/fr unknown
- 2020-02-19 LT LTPA2020502C patent/LTC2892347I2/lt unknown
- 2020-02-20 FI FIC20200007C patent/FIC20200007I1/fi unknown
- 2020-02-24 NO NO2020002C patent/NO2020002I1/no unknown
Also Published As
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