HRP20191044T1 - Oftalmološki pripravci i njihova uporaba - Google Patents
Oftalmološki pripravci i njihova uporaba Download PDFInfo
- Publication number
- HRP20191044T1 HRP20191044T1 HRP20191044TT HRP20191044T HRP20191044T1 HR P20191044 T1 HRP20191044 T1 HR P20191044T1 HR P20191044T T HRP20191044T T HR P20191044TT HR P20191044 T HRP20191044 T HR P20191044T HR P20191044 T1 HRP20191044 T1 HR P20191044T1
- Authority
- HR
- Croatia
- Prior art keywords
- preparation
- single use
- tropicamide
- concentration
- hydrochloride
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- 238000001356 surgical procedure Methods 0.000 claims 4
- BGDKAVGWHJFAGW-UHFFFAOYSA-N Tropicamide Chemical compound C=1C=CC=CC=1C(CO)C(=O)N(CC)CC1=CC=NC=C1 BGDKAVGWHJFAGW-UHFFFAOYSA-N 0.000 claims 3
- 238000002347 injection Methods 0.000 claims 3
- 239000007924 injection Substances 0.000 claims 3
- 239000000825 pharmaceutical preparation Substances 0.000 claims 3
- 229960004791 tropicamide Drugs 0.000 claims 3
- 239000000812 cholinergic antagonist Substances 0.000 claims 2
- 229960004393 lidocaine hydrochloride Drugs 0.000 claims 2
- YECIFGHRMFEPJK-UHFFFAOYSA-N lidocaine hydrochloride monohydrate Chemical compound O.[Cl-].CC[NH+](CC)CC(=O)NC1=C(C)C=CC=C1C YECIFGHRMFEPJK-UHFFFAOYSA-N 0.000 claims 2
- 239000003589 local anesthetic agent Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 229960003733 phenylephrine hydrochloride Drugs 0.000 claims 2
- OCYSGIYOVXAGKQ-FVGYRXGTSA-N phenylephrine hydrochloride Chemical compound [H+].[Cl-].CNC[C@H](O)C1=CC=CC(O)=C1 OCYSGIYOVXAGKQ-FVGYRXGTSA-N 0.000 claims 2
- 229940127230 sympathomimetic drug Drugs 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- 239000008215 water for injection Substances 0.000 claims 2
- 208000002177 Cataract Diseases 0.000 claims 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 claims 1
- 239000007900 aqueous suspension Substances 0.000 claims 1
- 229960004194 lidocaine Drugs 0.000 claims 1
- 229960001802 phenylephrine Drugs 0.000 claims 1
- SONNWYBIRXJNDC-VIFPVBQESA-N phenylephrine Chemical compound CNC[C@H](O)C1=CC=CC(O)=C1 SONNWYBIRXJNDC-VIFPVBQESA-N 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
Claims (4)
1. Farmaceutski pripravak za upotrebu u/za pripremi oka prije operacije ili tijekom kirurškog postupka, koji sadrži kombinaciju parasimpatolitičkog sredstva, simpatomimetičkog sredstva i lokalni anestetik, naznačen time da :
• pripravak sadrži :
- uključena je koncentracija Tropicamida kao parasimpatolitičko sredstvo
između 0.015 i 0.025%;
- koncentraciju lidokaina ili njegove soli, kao lokalni anestetik,
između 0,75 i 1,25%; i
- koncentracija fenilefrina, kao simpatomimetičko sredstvo između 0,2 i 0,4%;
• pripravak se primjenjuje intrakameralnom injekcijom ;
• operacija je operacija katarakte
2. Farmaceutski pripravak za njegovu upotrebu prema zahtjevu 1, naznačen time da, farmaceutski pripravak dolazi u obliku otopine ili vodene suspenzije , ili u bočici sa jednom dozom.
3. Pripravak za jednokratnu primjenu za intrakameralnu injekciju prije zahvata koji se sastoji od :
Tropicamid: 0,00024 g
Fenilefrin hidroklorid: 0,0038 g
Lidokain hidroklorid: 0,00917 g
Voda za injekcije q.s.p. za bočicu od 1 ml za jednokratnu uporabu
4. Pripravak za jednokratnu primjenu za intrakameralnu injekciju prije zahvata koji se sastoji od :
Tropicamid: 0,00016 g
Fenilefrin hidroklorid: 0,00258 g
Lidokain hidroklorid: 0,00943 g
Voda za injekcije q.s.p. za bočicu od 1 ml za jednokratnu uporabu
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0502357A FR2882930B1 (fr) | 2005-03-09 | 2005-03-09 | Nouvelles compositions ophtalmologiques et leur mode d'utilisation |
| PCT/FR2006/000528 WO2006095095A1 (fr) | 2005-03-09 | 2006-03-09 | Compositions ophtalmologiques et leur mode d’utilisation |
| EP06726059.6A EP1858481B1 (fr) | 2005-03-09 | 2006-03-09 | Compositions ophtalmologiques et leur utilisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20191044T1 true HRP20191044T1 (hr) | 2019-09-06 |
Family
ID=35058756
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20191044TT HRP20191044T1 (hr) | 2005-03-09 | 2019-06-11 | Oftalmološki pripravci i njihova uporaba |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US20080194649A1 (hr) |
| EP (1) | EP1858481B1 (hr) |
| JP (1) | JP2008532985A (hr) |
| KR (1) | KR20070111501A (hr) |
| CN (1) | CN101151018A (hr) |
| CA (1) | CA2598503C (hr) |
| CY (2) | CY1121865T1 (hr) |
| DK (1) | DK1858481T3 (hr) |
| ES (1) | ES2728071T3 (hr) |
| FR (1) | FR2882930B1 (hr) |
| HR (1) | HRP20191044T1 (hr) |
| HU (1) | HUE043668T2 (hr) |
| IL (1) | IL185197A0 (hr) |
| LT (2) | LT1858481T (hr) |
| LU (1) | LUC00136I2 (hr) |
| MA (1) | MA29269B1 (hr) |
| MX (1) | MX2007010295A (hr) |
| NL (1) | NL301017I2 (hr) |
| NO (2) | NO339793B1 (hr) |
| PL (1) | PL1858481T3 (hr) |
| PT (1) | PT1858481T (hr) |
| RU (1) | RU2392925C2 (hr) |
| SI (1) | SI1858481T1 (hr) |
| TN (1) | TNSN07343A1 (hr) |
| TR (1) | TR201908487T4 (hr) |
| WO (1) | WO2006095095A1 (hr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8602959B1 (en) * | 2010-05-21 | 2013-12-10 | Robert Park | Methods and devices for delivery of radiation to the posterior portion of the eye |
| WO2012111029A2 (en) * | 2011-02-18 | 2012-08-23 | M/S. Appasamy Associates | Ophthalmic composition for enabling dilation of pupils |
| ITPA20110004A1 (it) * | 2011-02-23 | 2012-08-24 | Francesco Paolo Montalto | Iniezione intracamerulare per anestesia e dilatazione pupillare (midriasi). |
| CN103159672A (zh) * | 2012-07-16 | 2013-06-19 | 湖南尔文生物科技有限公司 | 一种托品酰胺的制备方法 |
| AU2013201465B2 (en) | 2012-10-24 | 2016-03-03 | Rayner Surgical (Ireland) Limited | Stable preservative-free mydriatic and anti-inflammatory solutions for injection |
| RU2525512C1 (ru) * | 2013-03-28 | 2014-08-20 | федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации | Способ медикаментозного расширения ригидного зрачка перед проведением факоэмульсификации |
| JP2016532723A (ja) * | 2013-10-03 | 2016-10-20 | インプリミス・ファーマシューティカルズ・インコーポレイテッドＩｍｐｒｉｍｉｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | 眼内投与のためのエピネフリン系点眼用組成物及びその製造のための方法 |
| CN105213418B (zh) * | 2015-11-11 | 2019-01-22 | 中国人民解放军第四军医大学 | 一种眼科术前用复方滴眼液及其制备方法 |
| EP3503873A4 (en) * | 2016-08-25 | 2020-04-15 | Harrow IP, LLC | EPINEPHRINE-BASED OPHTHALMIC COMPOSITIONS FOR INTRAOCULAR ADMINISTRATION AND METHOD FOR THE PRODUCTION THEREOF |
| RU2649534C1 (ru) * | 2017-05-10 | 2018-04-03 | Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования "Российская медицинская академия непрерывного профессионального образования" Министерства здравоохранения Российской Федерации (ФГБОУ ДПО РМАНПО Минздрава России) | Способ анестезии при факоэмульсификации катаракты |
| RU2662423C1 (ru) * | 2017-07-26 | 2018-07-25 | Федеральное государственное автономное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации | Способ проведения обезболивания при выполнении витреоретинальных операций |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3026323A (en) * | 1960-03-22 | 1962-03-20 | Rubin J Schacter | Salts of tribasic acids |
| JPH0780760B2 (ja) * | 1986-07-28 | 1995-08-30 | ライオン株式会社 | 安定化されたフエニレフリン系液剤 |
| JP3066561B2 (ja) * | 1993-10-07 | 2000-07-17 | 武田薬品工業株式会社 | 近視予防・治療剤 |
| US5686414A (en) * | 1995-11-14 | 1997-11-11 | Xoma Corporation | Methods of treating conditions associated with corneal transplantation |
| US5779661A (en) * | 1995-12-11 | 1998-07-14 | Physion, S.R.L. | Method of treating dysfunctional bladder syndromes by electromotive drug administration |
| US6319240B1 (en) * | 1999-05-25 | 2001-11-20 | Iomed, Inc. | Methods and apparatus for ocular iontophoresis |
| AU2249701A (en) * | 1999-11-12 | 2001-06-06 | David Bernstein | Methods for treating cardiac arrest or pulmonary hypertension and compositions for use therein comprising vasoactive intestinal polypeptide and cardiac device for electrical and chemical regulation and methods of use |
| US6218428B1 (en) * | 2000-04-28 | 2001-04-17 | Emil Chynn | Ophthalmic composition |
| JP4150846B2 (ja) * | 2001-03-28 | 2008-09-17 | 参天製薬株式会社 | ステロイドを有効成分とする網脈絡膜疾患治療剤 |
| US20040013729A1 (en) * | 2002-07-18 | 2004-01-22 | Buono Lawrence M. | Single-drop multiple-agent composition for topical delivery to the eye |
| CN103143022A (zh) * | 2002-07-30 | 2013-06-12 | 奥默罗斯公司 | 眼科冲洗液及方法 |
-
2005
- 2005-03-09 FR FR0502357A patent/FR2882930B1/fr active Active
-
2006
- 2006-03-09 LT LTEP06726059.6T patent/LT1858481T/lt unknown
- 2006-03-09 KR KR1020077019402A patent/KR20070111501A/ko not_active Application Discontinuation
- 2006-03-09 MX MX2007010295A patent/MX2007010295A/es active IP Right Grant
- 2006-03-09 EP EP06726059.6A patent/EP1858481B1/fr active Active
- 2006-03-09 DK DK06726059.6T patent/DK1858481T3/da active
- 2006-03-09 WO PCT/FR2006/000528 patent/WO2006095095A1/fr active Application Filing
- 2006-03-09 CA CA2598503A patent/CA2598503C/fr active Active
- 2006-03-09 PT PT06726059T patent/PT1858481T/pt unknown
- 2006-03-09 HU HUE06726059A patent/HUE043668T2/hu unknown
- 2006-03-09 TR TR2019/08487T patent/TR201908487T4/tr unknown
- 2006-03-09 JP JP2008500234A patent/JP2008532985A/ja active Pending
- 2006-03-09 CN CNA2006800074102A patent/CN101151018A/zh active Pending
- 2006-03-09 SI SI200632328T patent/SI1858481T1/sl unknown
- 2006-03-09 ES ES06726059T patent/ES2728071T3/es active Active
- 2006-03-09 RU RU2007137115/15A patent/RU2392925C2/ru active
- 2006-03-09 US US11/908,161 patent/US20080194649A1/en not_active Abandoned
- 2006-03-09 PL PL06726059T patent/PL1858481T3/pl unknown
-
2007
- 2007-08-12 IL IL185197A patent/IL185197A0/en unknown
- 2007-08-27 MA MA30165A patent/MA29269B1/fr unknown
- 2007-09-07 TN TNP2007000343A patent/TNSN07343A1/fr unknown
- 2007-09-24 NO NO20074850A patent/NO339793B1/no active Protection Beyond IP Right Term
-
2012
- 2012-05-04 US US13/464,524 patent/US9289399B2/en active Active
-
2017
- 2017-03-24 NO NO2017008C patent/NO2017008I1/no unknown
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2019
- 2019-06-11 HR HRP20191044TT patent/HRP20191044T1/hr unknown
- 2019-08-05 CY CY20191100828T patent/CY1121865T1/el unknown
- 2019-10-30 NL NL301017C patent/NL301017I2/nl unknown
- 2019-11-04 LU LU00136C patent/LUC00136I2/fr unknown
- 2019-11-05 CY CY2019042C patent/CY2019042I1/el unknown
- 2019-11-07 LT LTPA2019017 patent/LTPA2019017I1/lt unknown
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