HRP20181645T1 - Monoklonalna antitijela prema progastrinu i njihove upotrebe - Google Patents

Monoklonalna antitijela prema progastrinu i njihove upotrebe

Info

Publication number
HRP20181645T1
HRP20181645T1 HRP20181645TT HRP20181645T HRP20181645T1 HR P20181645 T1 HRP20181645 T1 HR P20181645T1 HR P20181645T T HRP20181645T T HR P20181645TT HR P20181645 T HRP20181645 T HR P20181645T HR P20181645 T1 HRP20181645 T1 HR P20181645T1
Authority
HR
Croatia
Prior art keywords
progustrin
monoclonal antibodies
monoclonal
antibodies
Prior art date
Application number
HRP20181645TT
Other languages
English (en)
Croatian (hr)
Inventor
Julie Pannequin
Laure Boudier
Dominique Joubert
Frédéric HOLLANDE
Original Assignee
Progastrine Et Cancers S.À R.L.
Institut National De La Santé Et De La Recherche Médicale (Inserm)
Centre National De La Recherche Scientifique (C. N. R. S.)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43086711&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20181645(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Progastrine Et Cancers S.À R.L., Institut National De La Santé Et De La Recherche Médicale (Inserm), Centre National De La Recherche Scientifique (C. N. R. S.) filed Critical Progastrine Et Cancers S.À R.L.
Publication of HRP20181645T1 publication Critical patent/HRP20181645T1/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57419Specifically defined cancers of colon
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575Hormones
    • G01N2333/595Gastrins; Cholecystokinins [CCK]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HRP20181645TT 2009-10-16 2010-10-15 Monoklonalna antitijela prema progastrinu i njihove upotrebe HRP20181645T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25262509P 2009-10-16 2009-10-16
EP10768878.0A EP2488551B1 (en) 2009-10-16 2010-10-15 Monoclonal antibodies to progastrin and their uses
PCT/EP2010/006329 WO2011045080A2 (en) 2009-10-16 2010-10-15 Monoclonal antibodies to progastrin and their uses

Publications (1)

Publication Number Publication Date
HRP20181645T1 true HRP20181645T1 (hr) 2018-12-14

Family

ID=43086711

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20181645TT HRP20181645T1 (hr) 2009-10-16 2010-10-15 Monoklonalna antitijela prema progastrinu i njihove upotrebe

Country Status (42)

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EP (2) EP2488551B1 (enExample)
JP (3) JP5985987B2 (enExample)
KR (2) KR101640520B1 (enExample)
CN (2) CN102791735B (enExample)
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GE (1) GEP201706604B (enExample)
GT (1) GT201200114A (enExample)
HN (1) HN2012000708A (enExample)
HR (1) HRP20181645T1 (enExample)
IL (2) IL219019B (enExample)
IN (1) IN2012DN03348A (enExample)
LT (1) LT2488551T (enExample)
MA (1) MA33747B1 (enExample)
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NI (1) NI201200054A (enExample)
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PE (1) PE20121649A1 (enExample)
PH (1) PH12012500711B1 (enExample)
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SG (1) SG10201704933PA (enExample)
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TN (1) TN2012000159A1 (enExample)
TW (1) TWI537002B (enExample)
UA (1) UA106771C2 (enExample)
WO (1) WO2011045080A2 (enExample)
ZA (1) ZA201202642B (enExample)

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JP7338128B2 (ja) 2017-12-08 2023-09-05 イー、シー、エス、ビオトラッカー、エス、エー、アール、エル 癌診断における放射性標識プロガストリン
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CN112368579B (zh) * 2018-02-27 2024-05-03 Ecs前胃泌素股份有限公司 作为生物标记物的前胃泌素用于免疫疗法
TWI793238B (zh) * 2018-12-27 2023-02-21 偉喬生醫股份有限公司 體外檢測生物樣品之胃源性蛋白的方法及套組
US20220372125A1 (en) * 2019-10-02 2022-11-24 Aslan Pharmaceuticals Pte. Ltd. Antigen Specific Binding Domains and Antibody Molecules
CN112062846A (zh) * 2020-04-27 2020-12-11 杭州博茵生物技术有限公司 一种g-17单克隆抗体及其应用
CN115785273B (zh) * 2021-09-10 2023-10-31 东莞市朋志生物科技有限公司 一种抗胃蛋白酶原i的抗体及其应用
CN115724949A (zh) * 2022-12-12 2023-03-03 郑州伊美诺生物技术有限公司 一种鼠源lgG单克隆抗体及其制备方法、应用
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ES2754774T3 (es) * 2010-03-24 2020-04-20 Progastrine Et Cancers S A R L Profilaxis de cáncer colorrectal y gastrointestinal
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Publication number Publication date
BR112012008818B1 (pt) 2021-10-19
US10385126B2 (en) 2019-08-20
JP2013507138A (ja) 2013-03-04
JP5985987B2 (ja) 2016-09-06
SI2488551T1 (sl) 2019-01-31
KR101640520B1 (ko) 2016-07-19
AR078659A1 (es) 2011-11-23
US11299542B2 (en) 2022-04-12
US9611320B2 (en) 2017-04-04
EP2488551A2 (en) 2012-08-22
NZ599971A (en) 2014-12-24
PL3421493T3 (pl) 2024-04-29
ZA201202642B (en) 2013-06-26
IL219019B (en) 2019-05-30
UA106771C2 (uk) 2014-10-10
CU20120060A7 (es) 2013-04-19
CN102791735A (zh) 2012-11-21
PT2488551T (pt) 2018-10-31
GEP201706604B (en) 2017-01-25
CN102791735B (zh) 2016-05-18
IL254004A0 (en) 2017-10-31
HK1178183A1 (zh) 2013-09-06
EP3421493A1 (en) 2019-01-02
TWI537002B (zh) 2016-06-11
DK2488551T3 (en) 2018-10-08
IN2012DN03348A (enExample) 2015-10-23
CR20120184A (es) 2012-08-20
CN104628857A (zh) 2015-05-20
MX351635B (es) 2017-10-23
IL254004B2 (en) 2023-06-01
TW201119675A (en) 2011-06-16
NI201200054A (es) 2012-08-20
CL2012000914A1 (es) 2012-09-14
EP3421493B1 (en) 2024-01-17
US20170306012A1 (en) 2017-10-26
US20200002413A1 (en) 2020-01-02
US20170174761A1 (en) 2017-06-22
TN2012000159A1 (en) 2013-12-12
GT201200114A (es) 2014-08-11
ECSP12011796A (es) 2012-06-29
JP6272793B2 (ja) 2018-01-31
ES2973217T3 (es) 2024-06-19
EA201791876A1 (ru) 2018-01-31
EP3421493C0 (en) 2024-01-17
AU2010306119A1 (en) 2012-05-03
EA029271B1 (ru) 2018-03-30
EA201200597A1 (ru) 2012-12-28
EP2488551B1 (en) 2018-07-25
JP2017212992A (ja) 2017-12-07
HN2012000708A (es) 2015-06-22
ES2690943T3 (es) 2018-11-23
SMT201800628T1 (it) 2019-01-11
CA2777691C (en) 2018-02-27
PE20121649A1 (es) 2012-12-08
US10377821B2 (en) 2019-08-13
US20170306011A1 (en) 2017-10-26
CA2777691A1 (en) 2011-04-21
US20220195035A1 (en) 2022-06-23
IL219019A0 (en) 2012-06-28
US20180022802A1 (en) 2018-01-25
SG10201704933PA (en) 2017-07-28
MA33747B1 (fr) 2012-11-01
NZ701709A (en) 2016-06-24
KR20150082672A (ko) 2015-07-15
AP2012006262A0 (en) 2012-06-30
US20110117086A1 (en) 2011-05-19
PL2488551T3 (pl) 2019-01-31
JP2015145380A (ja) 2015-08-13
WO2011045080A2 (en) 2011-04-21
CU24196B1 (es) 2016-09-30
CY1120913T1 (el) 2019-12-11
PH12012500711A1 (en) 2012-11-12
KR20120091221A (ko) 2012-08-17
US10385125B2 (en) 2019-08-20
PH12012500711B1 (en) 2019-04-24
LT2488551T (lt) 2018-10-25
RS57966B1 (sr) 2019-01-31
WO2011045080A3 (en) 2011-07-07
MX2012004400A (es) 2012-06-27
US10385124B2 (en) 2019-08-20
BR112012008818A2 (pt) 2018-05-22

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