HRP20170611T1 - Vaginaleta koja sadrži mliječnu kiselinu - Google Patents
Vaginaleta koja sadrži mliječnu kiselinu Download PDFInfo
- Publication number
- HRP20170611T1 HRP20170611T1 HRP20170611TT HRP20170611T HRP20170611T1 HR P20170611 T1 HRP20170611 T1 HR P20170611T1 HR P20170611T T HRP20170611T T HR P20170611TT HR P20170611 T HRP20170611 T HR P20170611T HR P20170611 T1 HRP20170611 T1 HR P20170611T1
- Authority
- HR
- Croatia
- Prior art keywords
- accordance
- lactic acid
- vaginalette
- vaginalet
- urogenital tract
- Prior art date
Links
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 title claims 10
- 239000004310 lactic acid Substances 0.000 title claims 5
- 235000014655 lactic acid Nutrition 0.000 title claims 5
- 239000006216 vaginal suppository Substances 0.000 title 1
- 229940120293 vaginal suppository Drugs 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 8
- 208000035475 disorder Diseases 0.000 claims 8
- 244000005706 microflora Species 0.000 claims 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 3
- 230000003472 neutralizing effect Effects 0.000 claims 3
- 230000002265 prevention Effects 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- 208000004926 Bacterial Vaginosis Diseases 0.000 claims 2
- 206010017533 Fungal infection Diseases 0.000 claims 2
- 208000031888 Mycoses Diseases 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- 208000037009 Vaginitis bacterial Diseases 0.000 claims 2
- 230000000845 anti-microbial effect Effects 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (14)
1. Vaginaleta koja sadrža inertni nositelj i mliječnu kiselinu ili njenu sol za liječenje i/ili prevenciju poremećaja u urogenitalnom traktu, naznačena time da spomenuta vaginaleta sadrži mliječnu kiselinu ili njenu sol u koncentraciji od 11-15 % po masi.
2. Vaginaleta sukladno patentnom zahtjevu 1, pri tome spomenuta vaginaleta sadrži mliječnu kiselinu ili njenu sol u koncentraciji od 13-15 % po masi
3. Vaginaleta sukladno bilo kojem od patentnih zahtjeva 1 ili 2, pri tome spomenuti inertni nositelj sadrži polietilen glikol (PEG).
4. Vaginaleta u skladu s bilo kojim od prethodnih patentnih zahtjeva, koje dalje sadrži neutralizirajuću tvar.
5. Vaginaleta sukladno patentnom zahtjevu 4, pri tome je sadržaj mliječne kiseline i neutralizirajuće tvari takav da je pH unutar opsega od 3.5 do 4.5.
6. Vaginaleta sukladno patentnom zahtjevu 4 ili 5, pri tome je spomenuta neutralizirajuća tvar natrij hidroksid.
7. Uporaba vaginalete u skladu s bilo kojim od patentnih zahtjeva 1-6 za proizvodnju lijekova radi prevencije i/ili liječenja poremećaja u urogenitalnom traktu.
8. Uporaba sukladno patentnom zahtjevu 7, pri tome spomenuti lijek ima antimikrobno djelovanje.
9. Uporaba sukladno patentnom zahtjevu 7 ili 8, pri tome spomenuti poremećaj uključuje povišeni pH i/ili poremećaj mikroflore u urogenitalnom traktu.
10. Uporaba u skladu s bilo kojim od patentnih zahtjeva 7-9, pri tome je spomenuti poremećaj odabran iz skupine koja se sastoji od bakterijske vaginoze, intermedijarne vaginalne mikroflore i gljivičnih infekcija.
11. Vaginaleta u skladu s bilo kojim od patentnih zahtjeva 1-6 za uporabu u prevenciji i/ili liječenju poremećaja u urogenitalnom traktu.
12. Vaginaleta za uporabu suklano patentnom zahtjevu 11, pri tome spomenute vaginalete imaju antimikrobno djelovanje.
13. Vaginaleta za uporabu sukladno patentnom zahtjevu 11 ili 12, pri tome spomenuti poremećaj uključuje povišeni pH i/ili poremećenu mikrofloru u urogenitalnom traktu.
14. Vaginaleta za uporabu u sukladu s bilo kojim od patentnih zahtjeva 11-13, pri tome je spomenuti poremećaj odabran iz skupine koja se sastoji od bakterijske vaginoze, intermedijarne vaginalne mikroflore, i gljivičnih infekcija.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08157575A EP2130531A1 (en) | 2008-06-04 | 2008-06-04 | Vaginal suppository comprising lactic acid |
| PCT/EP2009/056818 WO2009147173A1 (en) | 2008-06-04 | 2009-06-03 | Vaginal suppository comprising lactic acid |
| EP09757554.2A EP2306973B1 (en) | 2008-06-04 | 2009-06-03 | Vaginal suppository comprising lactic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20170611T1 true HRP20170611T1 (hr) | 2017-07-28 |
Family
ID=40040177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20170611TT HRP20170611T1 (hr) | 2008-06-04 | 2017-04-18 | Vaginaleta koja sadrži mliječnu kiselinu |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8871244B2 (hr) |
| EP (2) | EP2130531A1 (hr) |
| CN (1) | CN102046148A (hr) |
| ES (1) | ES2623382T3 (hr) |
| HR (1) | HRP20170611T1 (hr) |
| HU (1) | HUE032893T2 (hr) |
| PT (1) | PT2306973T (hr) |
| SI (1) | SI2306973T1 (hr) |
| WO (1) | WO2009147173A1 (hr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012092990A2 (de) | 2011-01-05 | 2012-07-12 | Udo Wenske | Medizinprodukt zur verbesserung der konzeptionsfähigkeit eines säugetiers |
| EP2809301A1 (en) | 2012-01-31 | 2014-12-10 | Biosoma B.V. | Method for administration of a probiotic |
| CN110693812A (zh) | 2012-06-13 | 2020-01-17 | 伊沃菲姆股份有限公司 | 用于增强避孕杀微生物剂有效性的组合物和方法 |
| JP2016531164A (ja) | 2013-05-30 | 2016-10-06 | エスセーアー・ハイジーン・プロダクツ・アーベー | 緩衝化乳酸を含む組成物 |
| US11337989B2 (en) | 2013-12-19 | 2022-05-24 | Evofem, Inc. | Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound |
| CN103908469B (zh) * | 2014-04-10 | 2016-03-23 | 南京明生医药技术有限公司 | 一种调节阴道微生态平衡和/或治疗萎缩性阴道炎的组合物及其应用 |
| CN108235682A (zh) | 2015-09-29 | 2018-06-29 | 金伯利-克拉克环球有限公司 | 用于维护微生物群落的健康平衡的协同组合物 |
| CN110225750A (zh) | 2016-10-04 | 2019-09-10 | 伊沃菲姆股份有限公司 | 细菌性阴道病的治疗和预防方法 |
| AU2017401761B2 (en) | 2017-02-28 | 2023-08-31 | Kimberly-Clark Worldwide, Inc. | Synergistic composition for maintenance of healthy balance of microflora |
| ES2811365T3 (es) * | 2017-12-21 | 2021-03-11 | S I I T S R L Servizio Int Imballaggi Termosaldanti | Macrogols para aplicación a la mucosa, y sus usos terapéuticos |
| IT201900024132A1 (it) * | 2019-12-16 | 2021-06-16 | Idi Integratori Dietetici Italiani S R L | Miscela e composizioni a base di oro e grafene, e loro uso. |
| US11850303B2 (en) | 2020-10-27 | 2023-12-26 | Uqora, Inc. | Gel and a suppository and methods to provide the gel and suppository |
| GB202018068D0 (en) * | 2020-11-17 | 2020-12-30 | Ucl Business Ltd | Pharmaceutical composition |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI68812C (fi) * | 1978-08-21 | 1985-11-11 | Dow Chemical Co | Foerfarande foer framstaellning av terapeutiskt effektiva 1- och d,1-glausinlactatsalter |
| RO80931A2 (ro) * | 1980-12-16 | 1983-02-01 | Intreprinderea De Medicamente "Terapia",Ro | Globule vaginale |
| SE8603338D0 (sv) | 1986-08-07 | 1986-08-07 | Bjorn Andersch | Medel for behandling av tillstand i slidan |
| DE19737348C2 (de) * | 1997-08-27 | 2002-07-25 | Dan-Gabriel Vulpescu | Neue Clindamycin und Clotrimazol enthaltende pharmazeutische Zusammensetzung |
| US20040047910A1 (en) * | 2000-07-07 | 2004-03-11 | Christian Beckett | Suppository and composition comprising at least one polyethylene glycol |
| HU224320B1 (hu) * | 2001-05-23 | 2005-07-28 | József Szabó | Lizozimot vagy lizozim-hidrokloridot tartalmazó hüvelyfertőtlenítő kúp |
| SE528337C2 (sv) | 2004-06-23 | 2006-10-24 | Nestor Medical Ab | Sammansättning innefattande mjölksyra och laktoferrin, eller ett peptidfragment därav, och användning av denna sammansättning för behandling av tillstånd i urogenitalsystemet |
| US7786176B2 (en) * | 2005-07-29 | 2010-08-31 | Kimberly-Clark Worldwide, Inc. | Vaginal treatment composition containing xylitol |
| AU2006209263A1 (en) * | 2005-09-12 | 2007-03-29 | Mcneil-Ppc, Inc. | Anhydrous composition containing an acid-acid buffer system |
-
2008
- 2008-06-04 EP EP08157575A patent/EP2130531A1/en not_active Withdrawn
-
2009
- 2009-06-03 EP EP09757554.2A patent/EP2306973B1/en active Active
- 2009-06-03 CN CN2009801198604A patent/CN102046148A/zh active Pending
- 2009-06-03 SI SI200931645A patent/SI2306973T1/sl unknown
- 2009-06-03 ES ES09757554.2T patent/ES2623382T3/es active Active
- 2009-06-03 WO PCT/EP2009/056818 patent/WO2009147173A1/en active Application Filing
- 2009-06-03 HU HUE09757554A patent/HUE032893T2/hu unknown
- 2009-06-03 PT PT97575542T patent/PT2306973T/pt unknown
- 2009-06-03 US US12/996,247 patent/US8871244B2/en active Active
-
2014
- 2014-09-25 US US14/496,737 patent/US10016358B2/en active Active
-
2017
- 2017-04-18 HR HRP20170611TT patent/HRP20170611T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US8871244B2 (en) | 2014-10-28 |
| EP2306973A1 (en) | 2011-04-13 |
| US20150080467A1 (en) | 2015-03-19 |
| ES2623382T3 (es) | 2017-07-11 |
| US10016358B2 (en) | 2018-07-10 |
| HUE032893T2 (hu) | 2017-11-28 |
| US20110098357A1 (en) | 2011-04-28 |
| EP2306973B1 (en) | 2017-01-25 |
| PT2306973T (pt) | 2017-04-26 |
| SI2306973T1 (sl) | 2017-06-30 |
| WO2009147173A1 (en) | 2009-12-10 |
| EP2130531A1 (en) | 2009-12-09 |
| CN102046148A (zh) | 2011-05-04 |
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