HRP20150612T1 - Postupci i pripravci koji sadrže supramolekulske konstrukte - Google Patents

Postupci i pripravci koji sadrže supramolekulske konstrukte Download PDF

Info

Publication number
HRP20150612T1
HRP20150612T1 HRP20150612TT HRP20150612T HRP20150612T1 HR P20150612 T1 HRP20150612 T1 HR P20150612T1 HR P20150612T T HRP20150612T T HR P20150612TT HR P20150612 T HRP20150612 T HR P20150612T HR P20150612 T1 HRP20150612 T1 HR P20150612T1
Authority
HR
Croatia
Prior art keywords
seq
antibody
antigenic
active fragment
antibody according
Prior art date
Application number
HRP20150612TT
Other languages
English (en)
Croatian (hr)
Inventor
Claude Yves Nicolau
Ruth Greferath
David Hickman
Original Assignee
Ac Immune Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/783,975 external-priority patent/US20040242845A1/en
Priority claimed from US10/958,211 external-priority patent/US8663650B2/en
Application filed by Ac Immune Sa filed Critical Ac Immune Sa
Publication of HRP20150612T1 publication Critical patent/HRP20150612T1/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0007Nervous system antigens; Prions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6093Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HRP20150612TT 2004-02-20 2015-06-08 Postupci i pripravci koji sadrže supramolekulske konstrukte HRP20150612T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/783,975 US20040242845A1 (en) 2003-02-21 2004-02-20 Methods and compositions comprising supramolecular antigenic constructs and antibodies elicited against them
US10/958,211 US8663650B2 (en) 2003-02-21 2004-10-04 Methods and compositions comprising supramolecular constructs
EP12153152.9A EP2465533B1 (en) 2004-02-20 2005-02-22 Methods and compositions comprising supramolecular constructs

Publications (1)

Publication Number Publication Date
HRP20150612T1 true HRP20150612T1 (hr) 2015-07-03

Family

ID=46395388

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20150612TT HRP20150612T1 (hr) 2004-02-20 2015-06-08 Postupci i pripravci koji sadrže supramolekulske konstrukte

Country Status (10)

Country Link
JP (1) JP4934433B2 (enExample)
KR (1) KR101277004B1 (enExample)
CY (1) CY1116316T1 (enExample)
DK (1) DK2465533T3 (enExample)
ES (2) ES2385226T3 (enExample)
HR (1) HRP20150612T1 (enExample)
HU (1) HUE025186T2 (enExample)
PT (1) PT2465533E (enExample)
RS (1) RS54074B1 (enExample)
SI (1) SI2465533T1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE055739T2 (hu) * 2009-03-18 2021-12-28 Ac Immune Sa Eljárás terápiás alkalmazásra
JP6027011B2 (ja) * 2010-10-26 2016-11-16 エーシー イミューン ソシエテ アノニム 疎水性部分によって修飾されたペプチドを含むリポソームベースの構築物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6187335B1 (en) * 1997-12-31 2001-02-13 Orasomal Technologies, Inc. Polymerizable fatty acids, phospholipids and polymerized liposomes therefrom
AU2600499A (en) * 1998-02-13 1999-08-30 Arch Development Corporation Methods and compositions comprising the use of blocked b-amyloid peptide
MXPA02006215A (es) * 1999-12-22 2003-10-15 Nektar Therapeutics Al Corp Metodo para preparar esteres de 1-benzotriazolil carbonato de poli(etilenglicol).

Also Published As

Publication number Publication date
SI2465533T1 (sl) 2015-07-31
DK2465533T3 (en) 2015-04-20
ES2539262T3 (es) 2015-06-29
ES2385226T9 (es) 2013-10-10
HK1172260A1 (en) 2013-04-19
ES2385226T3 (es) 2012-07-19
HK1130698A1 (en) 2010-01-08
CY1116316T1 (el) 2017-02-08
JP4934433B2 (ja) 2012-05-16
HUE025186T2 (en) 2016-02-29
JP2007527870A (ja) 2007-10-04
PT2465533E (pt) 2015-06-24
KR101277004B1 (ko) 2013-06-24
RS54074B1 (sr) 2015-10-30
KR20120097546A (ko) 2012-09-04

Similar Documents

Publication Publication Date Title
ES2407429T3 (es) Vacuna terapéurica
ES2360465T3 (es) Composición de péptido inmunogénico para la prevención y el tratamiento de la enfermedad de alzheimer.
ES2368907T3 (es) Procedimientos y composiciones inmunológicas para el tratamiento de la enfermedad de alzheimer.
ES2229800T3 (es) Conjugados de hapteno-soporte para tratar y prevenir la adiccion a la nicotina.
ES2238049T3 (es) Peptidos sinteticos inmunogenicos pero no amiloidogenicos homologos a los beta amiloides para la induccion de una respuesta inmunitaria a los depositos amiloides y beta-amiloides.
CN101420983B (zh) 包含超分子抗原构建体的组合物和方法
US11419924B2 (en) Immunotherapeutic compositions for the treatment of Alzheimer's disease
US7790172B2 (en) Methods for reducing nasopharyngeal colonization of non-typable Haemophilus influenzae with synthetic chimeric fimbrin peptides
JP5161796B2 (ja) 抗アミロイド免疫原性組成物、方法、および使用
ES2474173T3 (es) Conjugados de portador pept�dico inmunog�nico beta y métodos de producir los mismos
ES2548102T3 (es) Anticuerpo monoclonal anti beta amiloide
DE68917126T2 (de) T-zellen-epitope als träger für einen konjugierten impfstoff.
JP5419131B2 (ja) 治療的特性を有するβ1〜42特異的モノクローナル抗体
HRP20150612T1 (hr) Postupci i pripravci koji sadrže supramolekulske konstrukte
RU2001130068A (ru) Антиидиотипические антитела к антителам, которые ингибируют связывание иммуноглобулина с его высокоаффинным рецептором
Vingtdeux et al. A modification-specific peptide-based immunization approach using CRM197 carrier protein: Development of a selective vaccine against pyroglutamate Aβ peptides
Zuercher et al. Intranasal immunisation with conjugate vaccine protects mice from systemic and respiratory tract infection with Pseudomonas aeruginosa
ES2923643T3 (es) Anticuerpos monoclonales anti-(+)--metanfetamina
Li et al. Prophylactic vaccine based on pyroglutamate-3 amyloid β generates strong antibody response and rescues cognitive decline in Alzheimer’s disease model mice
CN110759987B (zh) 构象特异性的重组Aβ1-42样寡聚体抗原、其制备方法和应用
TW201018478A (en) Immunotherapy compositions for the treatment and prevention of amyloidosis
JP2021533201A (ja) Peg化破傷風神経毒素および筋緊張低下の治療
CN117586370A (zh) 强毒性淀粉样蛋白寡聚体及其用途
CN103539840A (zh) 表皮生长因子受体模拟表位肽及其应用
CA2347700A1 (en) Antibodies to peptides that target git receptors and related methods