JP4934433B2 - 超分子コンストラクトを含む方法および組成物 - Google Patents

超分子コンストラクトを含む方法および組成物 Download PDF

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Publication number
JP4934433B2
JP4934433B2 JP2006554250A JP2006554250A JP4934433B2 JP 4934433 B2 JP4934433 B2 JP 4934433B2 JP 2006554250 A JP2006554250 A JP 2006554250A JP 2006554250 A JP2006554250 A JP 2006554250A JP 4934433 B2 JP4934433 B2 JP 4934433B2
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peptide
composition
amyloid
antibodies
antibody
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Japanese (ja)
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JP2007527870A (ja
JP2007527870A5 (enExample
Inventor
イヴ クロード ニコラウ
ルース グルフェラス
デビッド ヒックマン
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エーシー イミューン ソシエテ アノニム
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Priority claimed from US10/783,975 external-priority patent/US20040242845A1/en
Priority claimed from US10/958,211 external-priority patent/US8663650B2/en
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Publication of JP2007527870A5 publication Critical patent/JP2007527870A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0007—Nervous system antigens; Prions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2006554250A 2004-02-20 2005-02-22 超分子コンストラクトを含む方法および組成物 Expired - Fee Related JP4934433B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10/783,975 US20040242845A1 (en) 2003-02-21 2004-02-20 Methods and compositions comprising supramolecular antigenic constructs and antibodies elicited against them
US10/783,975 2004-02-20
US10/958,211 US8663650B2 (en) 2003-02-21 2004-10-04 Methods and compositions comprising supramolecular constructs
US10/958,211 2004-10-04
PCT/US2005/005285 WO2005081872A2 (en) 2004-02-20 2005-02-22 Methods and compositions comprising supramolecular constructs

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011131772A Division JP2011251964A (ja) 2004-02-20 2011-06-14 超分子コンストラクトを含む方法および組成物

Publications (3)

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JP2007527870A JP2007527870A (ja) 2007-10-04
JP2007527870A5 JP2007527870A5 (enExample) 2011-08-04
JP4934433B2 true JP4934433B2 (ja) 2012-05-16

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JP2006554250A Expired - Fee Related JP4934433B2 (ja) 2004-02-20 2005-02-22 超分子コンストラクトを含む方法および組成物

Country Status (10)

Country Link
JP (1) JP4934433B2 (enExample)
KR (1) KR101277004B1 (enExample)
CY (1) CY1116316T1 (enExample)
DK (1) DK2465533T3 (enExample)
ES (2) ES2385226T3 (enExample)
HR (1) HRP20150612T1 (enExample)
HU (1) HUE025186T2 (enExample)
PT (1) PT2465533E (enExample)
RS (1) RS54074B1 (enExample)
SI (1) SI2465533T1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE055739T2 (hu) * 2009-03-18 2021-12-28 Ac Immune Sa Eljárás terápiás alkalmazásra
JP6027011B2 (ja) * 2010-10-26 2016-11-16 エーシー イミューン ソシエテ アノニム 疎水性部分によって修飾されたペプチドを含むリポソームベースの構築物

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999041279A2 (en) * 1998-02-13 1999-08-19 Arch Development Corporation Methods and compositions comprising the use of blocked b-amyloid peptide
JP2002500165A (ja) * 1997-12-31 2002-01-08 オラソマル テクノロジーズ，インコーポレーテッド 新規の重合性の脂肪酸、リン脂質、及びそれから得られた重合リポソーム
JP2003518151A (ja) * 1999-12-22 2003-06-03 シアウォーター・コーポレイション ポリ（エチレングリコール）の１−ベンゾトリアゾリル炭酸エステルの調製のための方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002500165A (ja) * 1997-12-31 2002-01-08 オラソマル テクノロジーズ，インコーポレーテッド 新規の重合性の脂肪酸、リン脂質、及びそれから得られた重合リポソーム
WO1999041279A2 (en) * 1998-02-13 1999-08-19 Arch Development Corporation Methods and compositions comprising the use of blocked b-amyloid peptide
JP2003518151A (ja) * 1999-12-22 2003-06-03 シアウォーター・コーポレイション ポリ（エチレングリコール）の１−ベンゾトリアゾリル炭酸エステルの調製のための方法

Also Published As

Publication number Publication date
SI2465533T1 (sl) 2015-07-31
DK2465533T3 (en) 2015-04-20
ES2539262T3 (es) 2015-06-29
ES2385226T9 (es) 2013-10-10
HK1172260A1 (en) 2013-04-19
ES2385226T3 (es) 2012-07-19
HK1130698A1 (en) 2010-01-08
CY1116316T1 (el) 2017-02-08
HRP20150612T1 (hr) 2015-07-03
HUE025186T2 (en) 2016-02-29
JP2007527870A (ja) 2007-10-04
PT2465533E (pt) 2015-06-24
KR101277004B1 (ko) 2013-06-24
RS54074B1 (sr) 2015-10-30
KR20120097546A (ko) 2012-09-04

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