HRP20120910T1 - Derivati kinolina kao antibakterijska sredstva - Google Patents

Derivati kinolina kao antibakterijska sredstva Download PDF

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Publication number
HRP20120910T1
HRP20120910T1 HRP20120910TT HRP20120910T HRP20120910T1 HR P20120910 T1 HRP20120910 T1 HR P20120910T1 HR P20120910T T HRP20120910T T HR P20120910TT HR P20120910 T HRP20120910 T HR P20120910T HR P20120910 T1 HRP20120910 T1 HR P20120910T1
Authority
HR
Croatia
Prior art keywords
alkyl
compound
bacterial infection
infection
halo
Prior art date
Application number
HRP20120910TT
Other languages
English (en)
Croatian (hr)
Inventor
Koenraad Jozef Lodewijk Marcel Andries
Anil Koul
Jerôme Emile Georges GUILLEMONT
Elisabeth Thérese Jeanne Pasquier
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35768115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20120910(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HRP20120910T1 publication Critical patent/HRP20120910T1/hr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HRP20120910TT 2005-08-03 2006-07-31 Derivati kinolina kao antibakterijska sredstva HRP20120910T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05107155 2005-08-03
PCT/EP2006/064847 WO2007014934A2 (en) 2005-08-03 2006-07-31 Quinoline derivatives as antibacterial agents

Publications (1)

Publication Number Publication Date
HRP20120910T1 true HRP20120910T1 (hr) 2012-12-31

Family

ID=35768115

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20120910TT HRP20120910T1 (hr) 2005-08-03 2006-07-31 Derivati kinolina kao antibakterijska sredstva

Country Status (30)

Country Link
US (1) US8691800B2 (https=)
EP (1) EP1912649B1 (https=)
JP (1) JP5208739B2 (https=)
KR (1) KR101413094B1 (https=)
CN (1) CN101277698B (https=)
AP (1) AP2483A (https=)
AR (1) AR054888A1 (https=)
AU (1) AU2006274873B2 (https=)
BR (1) BRPI0614099B8 (https=)
CA (1) CA2615900C (https=)
CY (1) CY1113535T1 (https=)
DK (1) DK1912649T3 (https=)
EA (1) EA014834B1 (https=)
ES (1) ES2397358T3 (https=)
HR (1) HRP20120910T1 (https=)
IL (1) IL189140A (https=)
JO (1) JO2837B1 (https=)
ME (1) ME01485B (https=)
MX (1) MX2008001601A (https=)
MY (1) MY147637A (https=)
NO (1) NO342328B1 (https=)
NZ (1) NZ566012A (https=)
PL (1) PL1912649T3 (https=)
PT (1) PT1912649E (https=)
RS (1) RS52606B (https=)
SI (1) SI1912649T1 (https=)
TW (1) TWI385168B (https=)
UA (1) UA95911C2 (https=)
WO (1) WO2007014934A2 (https=)
ZA (1) ZA200801106B (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO2837B1 (en) 2005-08-03 2014-09-15 جانسن فارمسيتكا ان في Quinoline derivatives acting as antibacterial agents
JO3271B1 (ar) * 2006-12-06 2018-09-16 Janssen Pharmaceutica Nv مشتقات الكوينولين المضادة للجراثيم
JO2683B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JP5246715B2 (ja) 2009-01-27 2013-07-24 独立行政法人科学技術振興機構 蛋白質架橋阻害剤およびその用途
KR102110355B1 (ko) 2012-04-27 2020-05-14 얀센 파마슈티카 엔.브이. 항균성 퀴놀린 유도체
CA2869453C (en) 2012-04-27 2021-03-02 Janssen Pharmaceutica Nv Antibacterial quinoline derivatives
ES2934785T3 (es) * 2016-03-07 2023-02-27 Global Alliance For Tb Drug Development Inc Compuestos antibacterianos y usos de los mismos

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965572A (en) * 1996-10-28 1999-10-12 The United States Of America As Respresented By The Secretary Of The Army Methods for treating antibiotic-resistant infections
US6103905A (en) * 1997-06-19 2000-08-15 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
GB0101577D0 (en) * 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
AR040336A1 (es) * 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
DK1527050T3 (da) * 2002-07-25 2010-07-19 Janssen Pharmaceutica Nv Quinolin-derivater og deres anvendelse som mycobakterielle inhibitorer
AP2188A (en) * 2004-01-23 2010-12-14 Janssen Pharmaceutica Nv Substituted quinolines and their use as mycobacterial inhibitors.
JO2837B1 (en) 2005-08-03 2014-09-15 جانسن فارمسيتكا ان في Quinoline derivatives acting as antibacterial agents

Also Published As

Publication number Publication date
NZ566012A (en) 2011-02-25
CA2615900C (en) 2014-12-09
EP1912649A2 (en) 2008-04-23
PL1912649T3 (pl) 2013-03-29
NO342328B1 (no) 2018-05-07
CN101277698B (zh) 2011-06-22
HK1124232A1 (zh) 2009-07-10
SI1912649T1 (sl) 2013-01-31
CY1113535T1 (el) 2016-06-22
AP2483A (en) 2012-10-01
JP2009503021A (ja) 2009-01-29
EA014834B1 (ru) 2011-02-28
DK1912649T3 (da) 2013-01-21
US8691800B2 (en) 2014-04-08
EA200800513A1 (ru) 2008-06-30
ZA200801106B (en) 2009-09-30
ES2397358T3 (es) 2013-03-06
KR20080039961A (ko) 2008-05-07
IL189140A (en) 2014-07-31
KR101413094B1 (ko) 2014-07-01
RS52606B (sr) 2013-04-30
BRPI0614099A2 (pt) 2011-03-09
ME01485B (me) 2014-04-20
CN101277698A (zh) 2008-10-01
AU2006274873A1 (en) 2007-02-08
WO2007014934A8 (en) 2007-05-18
BRPI0614099B1 (pt) 2019-11-12
AU2006274873B2 (en) 2012-12-13
BRPI0614099B8 (pt) 2021-05-25
WO2007014934A3 (en) 2007-04-05
WO2007014934A2 (en) 2007-02-08
EP1912649B1 (en) 2012-10-10
TWI385168B (zh) 2013-02-11
NO20081068L (no) 2008-02-29
IL189140A0 (en) 2008-08-07
JO2837B1 (en) 2014-09-15
AR054888A1 (es) 2007-07-25
MY147637A (en) 2012-12-31
MX2008001601A (es) 2008-02-19
TW200800971A (en) 2008-01-01
UA95911C2 (ru) 2011-09-26
CA2615900A1 (en) 2007-02-08
US20080227775A1 (en) 2008-09-18
PT1912649E (pt) 2013-01-14
JP5208739B2 (ja) 2013-06-12

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