HRP20120416T1 - Postupci pripreme i uporabe smjesa kelata feri pirofosfat citrata - Google Patents
Postupci pripreme i uporabe smjesa kelata feri pirofosfat citrata Download PDFInfo
- Publication number
- HRP20120416T1 HRP20120416T1 HRP20120416AT HRP20120416T HRP20120416T1 HR P20120416 T1 HRP20120416 T1 HR P20120416T1 HR P20120416A T HRP20120416A T HR P20120416AT HR P20120416 T HRP20120416 T HR P20120416T HR P20120416 T1 HRP20120416 T1 HR P20120416T1
- Authority
- HR
- Croatia
- Prior art keywords
- ferric
- pyrophosphate
- citrate
- source
- amount
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract 12
- 239000013522 chelant Substances 0.000 title claims abstract 11
- 229940036417 ferric pyrophosphate citrate Drugs 0.000 title claims abstract 9
- SXAWSYZURCZSDX-UHFFFAOYSA-B hydron;[hydroxy(oxido)phosphoryl] hydrogen phosphate;2-hydroxypropane-1,2,3-tricarboxylate;iron(3+);phosphonato phosphate Chemical compound [H+].[H+].[H+].[H+].[H+].[Fe+3].[Fe+3].[Fe+3].[Fe+3].OP([O-])(=O)OP(O)([O-])=O.OP([O-])(=O)OP(O)([O-])=O.[O-]P([O-])(=O)OP([O-])([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O SXAWSYZURCZSDX-UHFFFAOYSA-B 0.000 title claims abstract 9
- 238000000034 method Methods 0.000 title claims 14
- 238000002360 preparation method Methods 0.000 title claims 2
- 229910019142 PO4 Inorganic materials 0.000 claims abstract 9
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims abstract 9
- 239000010452 phosphate Substances 0.000 claims abstract 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract 5
- 206010022971 Iron Deficiencies Diseases 0.000 claims abstract 2
- VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical compound [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 claims 13
- 229910001447 ferric ion Inorganic materials 0.000 claims 13
- XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 claims 9
- -1 citrate ions Chemical class 0.000 claims 8
- 235000011180 diphosphates Nutrition 0.000 claims 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims 5
- 239000008247 solid mixture Substances 0.000 claims 5
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims 3
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical group OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 3
- 239000000463 material Substances 0.000 claims 3
- 239000003960 organic solvent Substances 0.000 claims 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 229910052742 iron Inorganic materials 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 claims 1
- PKDWUXLRYBKARO-UHFFFAOYSA-L 2-hydroxypropane-1,2,3-tricarboxylic acid;iron(2+);phosphono phosphate Chemical compound [Fe+2].OP(O)(=O)OP([O-])([O-])=O.OC(=O)CC(O)(C(O)=O)CC(O)=O PKDWUXLRYBKARO-UHFFFAOYSA-L 0.000 claims 1
- FPFSGDXIBUDDKZ-UHFFFAOYSA-N 3-decyl-2-hydroxycyclopent-2-en-1-one Chemical compound CCCCCCCCCCC1=C(O)C(=O)CC1 FPFSGDXIBUDDKZ-UHFFFAOYSA-N 0.000 claims 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims 1
- 229910021578 Iron(III) chloride Inorganic materials 0.000 claims 1
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 claims 1
- 229910052782 aluminium Inorganic materials 0.000 claims 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims 1
- 229910052787 antimony Inorganic materials 0.000 claims 1
- WATWJIUSRGPENY-UHFFFAOYSA-N antimony atom Chemical compound [Sb] WATWJIUSRGPENY-UHFFFAOYSA-N 0.000 claims 1
- 229910052785 arsenic Inorganic materials 0.000 claims 1
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical compound [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 claims 1
- 229910052797 bismuth Inorganic materials 0.000 claims 1
- JCXGWMGPZLAOME-UHFFFAOYSA-N bismuth atom Chemical compound [Bi] JCXGWMGPZLAOME-UHFFFAOYSA-N 0.000 claims 1
- 229910052793 cadmium Inorganic materials 0.000 claims 1
- BDOSMKKIYDKNTQ-UHFFFAOYSA-N cadmium atom Chemical compound [Cd] BDOSMKKIYDKNTQ-UHFFFAOYSA-N 0.000 claims 1
- 235000015165 citric acid Nutrition 0.000 claims 1
- 229910052802 copper Inorganic materials 0.000 claims 1
- 239000010949 copper Substances 0.000 claims 1
- 238000000502 dialysis Methods 0.000 claims 1
- 239000002526 disodium citrate Substances 0.000 claims 1
- 235000019262 disodium citrate Nutrition 0.000 claims 1
- 235000019820 disodium diphosphate Nutrition 0.000 claims 1
- GYQBBRRVRKFJRG-UHFFFAOYSA-L disodium pyrophosphate Chemical group [Na+].[Na+].OP([O-])(=O)OP(O)([O-])=O GYQBBRRVRKFJRG-UHFFFAOYSA-L 0.000 claims 1
- CEYULKASIQJZGP-UHFFFAOYSA-L disodium;2-(carboxymethyl)-2-hydroxybutanedioate Chemical compound [Na+].[Na+].[O-]C(=O)CC(O)(C(=O)O)CC([O-])=O CEYULKASIQJZGP-UHFFFAOYSA-L 0.000 claims 1
- 238000004090 dissolution Methods 0.000 claims 1
- 150000002500 ions Chemical class 0.000 claims 1
- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 claims 1
- RUTXIHLAWFEWGM-UHFFFAOYSA-H iron(3+) sulfate Chemical compound [Fe+3].[Fe+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O RUTXIHLAWFEWGM-UHFFFAOYSA-H 0.000 claims 1
- VXWSFRMTBJZULV-UHFFFAOYSA-H iron(3+) sulfate hydrate Chemical compound O.[Fe+3].[Fe+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O VXWSFRMTBJZULV-UHFFFAOYSA-H 0.000 claims 1
- 229910000360 iron(III) sulfate Inorganic materials 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 claims 1
- 229910052753 mercury Inorganic materials 0.000 claims 1
- 229910052751 metal Inorganic materials 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 229910052750 molybdenum Inorganic materials 0.000 claims 1
- 239000011733 molybdenum Substances 0.000 claims 1
- HWPKGOGLCKPRLZ-UHFFFAOYSA-M monosodium citrate Chemical compound [Na+].OC(=O)CC(O)(C([O-])=O)CC(O)=O HWPKGOGLCKPRLZ-UHFFFAOYSA-M 0.000 claims 1
- 239000002524 monosodium citrate Substances 0.000 claims 1
- 235000018342 monosodium citrate Nutrition 0.000 claims 1
- 239000006186 oral dosage form Substances 0.000 claims 1
- 239000006201 parenteral dosage form Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims 1
- 239000001509 sodium citrate Substances 0.000 claims 1
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 235000019818 tetrasodium diphosphate Nutrition 0.000 claims 1
- 229910052716 thallium Inorganic materials 0.000 claims 1
- BKVIYDNLLOSFOA-UHFFFAOYSA-N thallium Chemical compound [Tl] BKVIYDNLLOSFOA-UHFFFAOYSA-N 0.000 claims 1
- 229910052718 tin Inorganic materials 0.000 claims 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 claims 1
- 229940038773 trisodium citrate Drugs 0.000 claims 1
- 235000019263 trisodium citrate Nutrition 0.000 claims 1
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical class [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 235000007144 ferric diphosphate Nutrition 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
- A61M1/287—Dialysates therefor
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Dental Preparations (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96132707P | 2007-07-20 | 2007-07-20 | |
| US12/138,018 US7816404B2 (en) | 2007-07-20 | 2008-06-12 | Methods for the preparation and use of ferric pyrophosphate citrate chelate compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20120416T1 true HRP20120416T1 (hr) | 2012-07-31 |
Family
ID=40019183
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20120416AT HRP20120416T1 (hr) | 2007-07-20 | 2012-05-15 | Postupci pripreme i uporabe smjesa kelata feri pirofosfat citrata |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7816404B2 (ja) |
| EP (1) | EP2016940B1 (ja) |
| JP (1) | JP5489196B2 (ja) |
| AT (1) | ATE554754T1 (ja) |
| CY (1) | CY1113903T1 (ja) |
| DK (1) | DK2016940T3 (ja) |
| ES (1) | ES2383713T3 (ja) |
| HR (1) | HRP20120416T1 (ja) |
| PL (1) | PL2016940T3 (ja) |
| PT (1) | PT2016940E (ja) |
| SI (1) | SI2016940T1 (ja) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090124572A1 (en) * | 2007-11-09 | 2009-05-14 | Deanna Jean Nelson | Iron-containing nutritional supplement |
| US8996104B2 (en) | 2008-06-25 | 2015-03-31 | Fe3 Medical, Inc. | Patches and method for the transdermal delivery of a therapeutically effective amount of iron |
| US20110288505A1 (en) * | 2008-09-29 | 2011-11-24 | Vifor (International) Ag | Receptacle And Method For Storing And Supplying A Liquid And A Liquid Medical Preparation |
| US8348922B2 (en) * | 2009-02-12 | 2013-01-08 | Incube Labs, Llc | Method and apparatus for oscillatory iontophoretic transdermal delivery of a therapeutic agent |
| US8961492B2 (en) | 2009-02-12 | 2015-02-24 | Incube Labs, Llc | System and method for controlling the iontophoretic delivery of therapeutic agents based on user inhalation |
| US8190252B2 (en) | 2009-02-12 | 2012-05-29 | Incube Labs, Llc | Iontophoretic system for transdermal delivery of active agents for therapeutic and medicinal purposes |
| US9008765B2 (en) | 2009-02-12 | 2015-04-14 | Incube Labs, Llc | System and method for biphasic transdermal iontophoretic delivery of therapeutic agents for the control of addictive cravings |
| US8821945B2 (en) * | 2009-04-25 | 2014-09-02 | Fe3 Medical, Inc. | Method for transdermal iontophoretic delivery of chelated agents |
| WO2010151845A2 (en) * | 2009-06-26 | 2010-12-29 | Incube Labs, Llc | Corrosion resistant electrodes for iontophoretic transdermal delivery devices and methods of use |
| US8178709B2 (en) * | 2009-07-21 | 2012-05-15 | Biolink Life Sciences, Inc. | Iron preparation suitable for pharmaceutical formulation and process for the preparation thereof |
| US8903485B2 (en) * | 2009-08-06 | 2014-12-02 | Incube Labs, Llc | Patch and patch assembly for iontophoretic transdermal delivery of active agents for therapeutic and medicinal purposes |
| US8685038B2 (en) | 2009-12-07 | 2014-04-01 | Incube Labs, Llc | Iontophoretic apparatus and method for marking of the skin |
| WO2011100376A2 (en) | 2010-02-10 | 2011-08-18 | Incube Labs, Llc | Methods and architecture for power optimization of iontophoretic transdermal drug delivery |
| EP2497380A1 (en) * | 2011-03-10 | 2012-09-12 | DSM IP Assets B.V. | Process for iron supplementation of beverages |
| EP2688639B1 (en) | 2011-03-24 | 2019-09-18 | Incube Labs, Llc | System for biphasic transdermal iontophoretic delivery of therapeutic agents |
| RU2472500C1 (ru) * | 2012-05-05 | 2013-01-20 | Илья Николаевич Медведев | Способ нормализации активности антитромбина iii в крови у новорожденных телят с железодефицитной анемией |
| US20150320091A1 (en) * | 2012-05-08 | 2015-11-12 | Dsm Ip Assets B.V. | Iron supplementation of rice kernels |
| JP2016507527A (ja) * | 2013-02-01 | 2016-03-10 | チャラク エルエルシー | 可溶性ピロリン酸第二鉄を用いて鉄欠乏症を治療する方法 |
| WO2015028272A1 (en) * | 2013-08-28 | 2015-03-05 | Dsm Ip Assets B.V. | Iron supplementation of a bouillon concentrate |
| JP6578293B2 (ja) | 2013-11-05 | 2019-09-18 | ロックウェル メディカル，インコーポレイテッド | 反応性が低下した患者のエリトロポエチン刺激剤の用量を減少させる方法 |
| EP3157516A4 (en) | 2014-06-22 | 2017-12-13 | Dexcel Pharma Technologies Ltd. | Pharmaceutical compositions comprising ferric citrate and methods for the production thereof |
| JP5963185B1 (ja) * | 2015-04-13 | 2016-08-03 | 富田製薬株式会社 | ピロリン酸第二鉄含有粉末及びその製造方法 |
| US10531684B2 (en) * | 2015-04-13 | 2020-01-14 | Tomita Pharmaceutical Co., Ltd. | Powder containing ferric pyrophosphate and method for producing same |
| KR20180050346A (ko) * | 2015-09-04 | 2018-05-14 | 락웰 메디컬, 인코포레이티드 | 가용성 고체 피로인산제2철(Soluble Ferric Pyrophosphate) 제제, 키트 및 이를 사용하는 방법 |
| US10456418B2 (en) * | 2015-10-05 | 2019-10-29 | Navinta, Llc | Preparation of pharmaceutical dosage forms containing iron (III) salts |
| CA3010771A1 (en) | 2016-01-06 | 2017-07-13 | Rockwell Medical, Inc. | Combination therapy with an iron compound and a citrate compound |
| CN106977552B (zh) * | 2016-01-19 | 2019-11-05 | 山东诚创医药技术开发有限公司 | 枸橼酸焦磷酸铁混配络合物的制备方法 |
| JP6887598B2 (ja) * | 2016-07-21 | 2021-06-16 | 富田製薬株式会社 | 鉄含有飲食品 |
| CN106619494A (zh) * | 2016-10-10 | 2017-05-10 | 泰州海达医药科技有限公司 | 枸橼酸焦磷酸铁溶液及其制备方法 |
| EP3599898B1 (en) | 2017-03-31 | 2022-08-17 | Abbott Laboratories | Liquid nutritional compositions containing oxidizable fish oil, rosmarinic acid and ferric iron |
| CN112159434A (zh) * | 2020-09-23 | 2021-01-01 | 北京沣瑞医药科技有限公司 | 枸橼酸焦磷酸铁配合物的制备方法 |
| CN112516163A (zh) * | 2020-12-21 | 2021-03-19 | 西安医学院 | 一种难溶性三价铁纳米脂质体复合物及其制备方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE579299A (ja) * | 1958-06-04 | |||
| US3275514A (en) * | 1960-04-12 | 1966-09-27 | Paul D Saltman | Process for introduction of metals into the mammalian system |
| US3259500A (en) * | 1961-10-11 | 1966-07-05 | Kentucky Res Foundation | Method for inhibiting anemia in young pigs by feeding the sow an iron agent |
| US3367834A (en) * | 1965-05-04 | 1968-02-06 | Dexter Martin | Method and compositions for enhancing the utilization of iron by mammals |
| AT279048B (de) * | 1967-07-04 | 1970-02-25 | Pharmazeutische Fabrik Montavit Gmbh | Verfahren zur Herstellung neuer, löslicher und stabiler organischer Eisen(III)-Komplexverbindungen und Injektionslösungen davon |
| US3686397A (en) * | 1970-05-18 | 1972-08-22 | Mueller Arthur | Parenteral iron preparations |
| SE359447B (ja) * | 1971-10-06 | 1973-09-03 | Astra Laekemedel Ab | |
| US4167564A (en) * | 1974-09-23 | 1979-09-11 | Albion Laboratories, Inc. | Biological assimilation of metals |
| US4058621A (en) * | 1975-02-24 | 1977-11-15 | Peter, Strong & Company, Inc. | Iron complexes and foodstuffs containing them |
| JPS5626709A (en) * | 1979-08-04 | 1981-03-14 | Nichia Kagaku Kogyo Kk | Manufacture of water soluble iron salt |
| GB2128998B (en) * | 1982-10-22 | 1986-07-16 | Nat Res Dev | Pharmaceutical compositions of iron complexes of 3 hydroxy-4-pyrone |
| US5177068A (en) * | 1984-04-19 | 1993-01-05 | National Research Development Corporation | Pharmaceutical compositions |
| GB8713169D0 (en) * | 1987-06-05 | 1987-07-08 | Peters T J | Uptake of iron by body |
| CO4410161A1 (es) | 1994-02-28 | 1997-01-09 | Kellog Co | Producto de cereal listo para comer fortificado con complejo de edta ferrico y metodo para producirlo |
| WO1998029434A1 (en) * | 1996-12-31 | 1998-07-09 | Ford Henry Health System | Method and pharmaceutical composition for iron delivery in hemodialysis and peritoneal dialysis patients |
| AU6605100A (en) | 1999-06-30 | 2001-01-31 | Ajay Gupta | Method and pharmaceutical composition for parenteral administration of iron |
| US20030190355A1 (en) | 2002-04-05 | 2003-10-09 | Hermelin Marc S. | Modified release minerals |
| TWI335218B (en) * | 2003-02-19 | 2011-01-01 | Panion & Bf Biotech Inc | Ferric organic compounds, uses thereof and methods of making same |
| US20060134227A1 (en) | 2004-12-22 | 2006-06-22 | Bortz Jonathan D | Compositions including iron |
| CN101384295B (zh) * | 2005-12-23 | 2014-10-29 | 阿贾伊·古普塔 | 含铁的肠胃外营养组合物 |
-
2008
- 2008-06-12 US US12/138,018 patent/US7816404B2/en active Active
- 2008-07-08 PL PL08159949T patent/PL2016940T3/pl unknown
- 2008-07-08 EP EP08159949A patent/EP2016940B1/en active Active
- 2008-07-08 ES ES08159949T patent/ES2383713T3/es active Active
- 2008-07-08 AT AT08159949T patent/ATE554754T1/de active
- 2008-07-08 PT PT08159949T patent/PT2016940E/pt unknown
- 2008-07-08 DK DK08159949.0T patent/DK2016940T3/da active
- 2008-07-08 SI SI200830627T patent/SI2016940T1/sl unknown
- 2008-07-18 JP JP2008186771A patent/JP5489196B2/ja active Active
-
2012
- 2012-05-15 HR HRP20120416AT patent/HRP20120416T1/hr unknown
- 2012-07-23 CY CY20121100653T patent/CY1113903T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US7816404B2 (en) | 2010-10-19 |
| DK2016940T3 (da) | 2012-06-18 |
| ATE554754T1 (de) | 2012-05-15 |
| EP2016940A1 (en) | 2009-01-21 |
| PL2016940T3 (pl) | 2012-09-28 |
| SI2016940T1 (sl) | 2012-07-31 |
| PT2016940E (pt) | 2012-07-12 |
| ES2383713T3 (es) | 2012-06-25 |
| JP5489196B2 (ja) | 2014-05-14 |
| CY1113903T1 (el) | 2016-07-27 |
| JP2009108027A (ja) | 2009-05-21 |
| US20090023686A1 (en) | 2009-01-22 |
| EP2016940B1 (en) | 2012-04-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20120416T1 (hr) | Postupci pripreme i uporabe smjesa kelata feri pirofosfat citrata | |
| McCann | The solubility of fluorapatite and its relationship to that of calcium fluoride | |
| US20070088161A1 (en) | Novel chelated bisphosphonates for use as pharmaceutical agents | |
| JP2016006096A5 (ja) | ||
| CN104071906B (zh) | 高效复合阻垢缓蚀剂 | |
| CN102127773B (zh) | 全无磷预清洗预膜药剂及清洗工艺 | |
| Chohan et al. | Transition metal acetylsalicylates and their anti-inflammatory activity | |
| JP2015110646A5 (ja) | ||
| CN107098832A (zh) | 一种和厚朴酚衍生物及其制备方法与应用 | |
| JPH01258693A (ja) | オキサアルカンポリホスホン酸ならびにそれを含む限界剤および錯化組成物 | |
| Cawthray et al. | In vivo study and thermodynamic investigation of two lanthanum complexes, La (dpp) 3 and La (XT), for the treatment of bone resorption disorders | |
| BR122019000367B1 (pt) | Processo para a inibição ou eliminação da formação de incrustações durante a produção de ácido fosfórico em um processo úmido | |
| CN104562031B (zh) | 一种预膜用组合物及预膜方法 | |
| CN111358991B (zh) | 一种鞋袜除臭抗菌组合物及其制备方法 | |
| US10456418B2 (en) | Preparation of pharmaceutical dosage forms containing iron (III) salts | |
| CN112439396A (zh) | 羟基乙叉二膦酸/羟基磷灰石有机无机杂化复合材料及其制备方法 | |
| CA2638081A1 (en) | Methods for the preparation and use of ferric pyrophosphate citrate chelate compositions | |
| JP2009522286A (ja) | 新規なフィチンクエン酸塩化合物および該化合物の製造方法 | |
| CN103450202B (zh) | L-5-甲基四氢叶酸与有机碱加成盐的方法 | |
| Cate et al. | Effect of impurities on density and viscosity of simulated wet-process phosphoric acid | |
| JP6689052B2 (ja) | ２価カチオン低含有カラギーナン及びその製造方法 | |
| Skorik | D-Metal folates and the folic acid–imidazole conjugate | |
| Knobloch et al. | Inosylyl (3′→ 5′) inosine (IpI–). Acid–Base and Metal Ion-Binding Properties of a Dinucleoside Monophosphate in Aqueous Solution | |
| JP2012518684A (ja) | ミネラル添加と酸処理を用いてメチオニンの溶解度を増加させる方法 | |
| ITRM970195A1 (it) | Composizioni solide atte alla somministrazione orale comprendenti l-carnitina e alcanoil l-carnitine magnesio tartrato |