HRP20110905T1 - Emolijentni pripravak - Google Patents
Emolijentni pripravak Download PDFInfo
- Publication number
- HRP20110905T1 HRP20110905T1 HR20110905T HRP20110905T HRP20110905T1 HR P20110905 T1 HRP20110905 T1 HR P20110905T1 HR 20110905 T HR20110905 T HR 20110905T HR P20110905 T HRP20110905 T HR P20110905T HR P20110905 T1 HRP20110905 T1 HR P20110905T1
- Authority
- HR
- Croatia
- Prior art keywords
- petroleum jelly
- preparation
- water
- preparation according
- oil
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract 5
- 239000003974 emollient agent Substances 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract 12
- 235000019271 petrolatum Nutrition 0.000 claims abstract 11
- 229940057995 liquid paraffin Drugs 0.000 claims abstract 5
- 229940099259 vaseline Drugs 0.000 claims abstract 4
- 239000007764 o/w emulsion Substances 0.000 claims abstract 3
- CZDYPVPMEAXLPK-UHFFFAOYSA-N tetramethylsilane Chemical compound C[Si](C)(C)C CZDYPVPMEAXLPK-UHFFFAOYSA-N 0.000 claims abstract 3
- 239000007762 w/o emulsion Substances 0.000 claims abstract 3
- 238000002360 preparation method Methods 0.000 claims 16
- 239000003814 drug Substances 0.000 claims 3
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims 2
- 206010012438 Dermatitis atopic Diseases 0.000 claims 2
- 201000008937 atopic dermatitis Diseases 0.000 claims 2
- 238000001460 carbon-13 nuclear magnetic resonance spectrum Methods 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 230000035515 penetration Effects 0.000 claims 2
- 238000011200 topical administration Methods 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- RFVNOJDQRGSOEL-UHFFFAOYSA-N 2-hydroxyethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCO RFVNOJDQRGSOEL-UHFFFAOYSA-N 0.000 claims 1
- WADQOGCINABPRT-UHFFFAOYSA-N 3-chloro-2-methylphenol Chemical compound CC1=C(O)C=CC=C1Cl WADQOGCINABPRT-UHFFFAOYSA-N 0.000 claims 1
- 201000004624 Dermatitis Diseases 0.000 claims 1
- 229920002701 Polyoxyl 40 Stearate Polymers 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 235000021355 Stearic acid Nutrition 0.000 claims 1
- 206010053615 Thermal burn Diseases 0.000 claims 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 229940008099 dimethicone Drugs 0.000 claims 1
- 235000013870 dimethyl polysiloxane Nutrition 0.000 claims 1
- 239000004205 dimethyl polysiloxane Substances 0.000 claims 1
- 239000012153 distilled water Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- YQEMORVAKMFKLG-UHFFFAOYSA-N glycerine monostearate Natural products CCCCCCCCCCCCCCCCCC(=O)OC(CO)CO YQEMORVAKMFKLG-UHFFFAOYSA-N 0.000 claims 1
- SVUQHVRAGMNPLW-UHFFFAOYSA-N glycerol monostearate Natural products CCCCCCCCCCCCCCCCC(=O)OCC(O)CO SVUQHVRAGMNPLW-UHFFFAOYSA-N 0.000 claims 1
- 206010021198 ichthyosis Diseases 0.000 claims 1
- 238000002844 melting Methods 0.000 claims 1
- 230000008018 melting Effects 0.000 claims 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims 1
- 229940057847 polyethylene glycol 600 Drugs 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 claims 1
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 claims 1
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 claims 1
- 208000017520 skin disease Diseases 0.000 claims 1
- 239000008117 stearic acid Substances 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- 229960004418 trolamine Drugs 0.000 claims 1
- 238000005481 NMR spectroscopy Methods 0.000 abstract 1
- 102000012479 Serine Proteases Human genes 0.000 abstract 1
- 108010022999 Serine Proteases Proteins 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000002682 anti-psoriatic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Developing Agents For Electrophotography (AREA)
Abstract
Pripravak za topičku upotrebu, naznačen time da sadrži kombinaciju vazelina i tekućeg parafina kao aktivne tvari u obliku ulje-u-vodi ili voda-u-ulju emulzije u kojoj vazelin ima točku ukapljavanja između 51°C i 57°C, konzistenciju između 175 1/10 mm i 195 1/10 mm (određeno metodom penetracija u obrnutom stošcu pri 25°C) te viskoznost između 4 cSt i 5 cSt pri 100°C. Patent sadrži još 11 patentnih zahtjeva.
Claims (12)
1. Pripravak za topičku upotrebu, naznačen time da sadrži kombinaciju vazelina i tekućeg parafina kao aktivne tvari u obliku ulje-u-vodi ili voda-u-ulju emulzije u kojoj vazelin ima točku ukapljavanja između 51°C i 57°C, konzistenciju između 175 1/10 mm i 195 1/10 mm (određeno metodom penetracija u obrnutom stošcu pri 25°C) te viskoznost između 4 cSt i 5 cSt pri 100°C.
2. Pripravak prema patentnom zahtjevu 1, naznačen time da 13C NMR spektar vazelina pri 500 MHz ima signal pri 24.55 ppm čije površina relativno prema kontrolnom 1% tetrametilsilanu (TMS) iznosi između 4 i 8.
3. Pripravak prema patentnom zahtjevu 1 ili 2, naznačen time da vazelin ima točku ukapljavanja pri 54°C.
4. Pripravak prema bilo kojem od prethodnih patentnih zahtjeva, naznačen time da je konzistencija vazelina približno 185 1/10 mm (određeno metodom penetracija u obrnutom stošcu pri 25°C).
5. Pripravak prema bilo kojem od prethodnih patentnih zahtjeva, naznačen time da vazelin ima viskoznost približno 4.8 cSt pri 100°C.
6. Pripravak prema bilo kojem od prethodnih patentnih zahtjeva, naznačen time da sadrži približno 15% glicerola, približno 8% vazelina te približno 2% tekućeg parafina.
7. Pripravak prema bilo kojem od prethodnih patentnih zahtjeva, naznačen time da sadrži jedan ili više ekscipijensa koji su odabrani iz sljedeće skupine: stearinska kiselina, glicerol-monostearat, polidimetilciklosiloksan, dimetikon, polietilenglikol 600, trolamin, propil parahidroksibenzoat, klorkrezol, PEG-40-stearat, destilirana voda.
8. Upotreba pripravka prema bilo kojem od prethodnih patentnih zahtjeva, naznačena time da je za pripravu lijeka za tretman stanja kutalne suhoće nekih dermatoza kao što je atopički dermatitis, stanja ihtioze i psorijaza.
9. Upotreba pripravka prema bilo kojem od patentnih zahtjeva 1 do 7, naznačena time da je za pripravu lijeka za tretman površinskih opeklina.
10. Upotreba pripravka prema bilo kojem od patentnih zahtjeva 1 do 7, naznačena time da je za pripravu lijeka za prevenciju i/ili tretman i/ili smanjivanje učestalosti i intenziteta napada ekcema opaženog među pacijentima koji pate od atopičkog dermatitisa.
11. Upotreba vazelina s točkom ukapljavanja između 51°C i 57°C, naznačena time da je za pripravu preparata za topičko davanje koji sadrži kombinaciju glicerola, vazelina i tekućeg parafina u obliku ulje-u-vodi ili voda-u-ulju emulzije.
12. Upotreba vazelina koji u 13C NMR spektru pri 500 MHz ima signal pri 24.55 ppm čija površina relativno prema kontrolnom 1% tetrametilsilani (TMS) iznosi između 4 i 8, naznačena time da je za pripravu preparata za topičko davanje koji sadrži kombinaciju glicerola, vazelina i tekućeg parafina u obliku ulje-u-vodi ili voda-u-ulju emulzije.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0853187A FR2931073B1 (fr) | 2008-05-16 | 2008-05-16 | Composition emolliente |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20110905T1 true HRP20110905T1 (hr) | 2011-12-31 |
Family
ID=40028914
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20110905T HRP20110905T1 (hr) | 2008-05-16 | 2011-12-02 | Emolijentni pripravak |
Country Status (27)
Country | Link |
---|---|
US (1) | US20110071226A1 (hr) |
EP (2) | EP2323639A1 (hr) |
JP (1) | JP5653911B2 (hr) |
KR (1) | KR20110023858A (hr) |
CN (2) | CN102026632A (hr) |
AT (1) | ATE523192T1 (hr) |
AU (1) | AU2009248047B2 (hr) |
BR (1) | BRPI0912506B1 (hr) |
CA (1) | CA2724522A1 (hr) |
CY (1) | CY1112150T1 (hr) |
DK (1) | DK2119435T3 (hr) |
ES (1) | ES2370465T3 (hr) |
FR (1) | FR2931073B1 (hr) |
GE (1) | GEP20135900B (hr) |
HK (1) | HK1203828A1 (hr) |
HR (1) | HRP20110905T1 (hr) |
IL (1) | IL209334A (hr) |
MA (1) | MA32396B1 (hr) |
MX (1) | MX2010012352A (hr) |
NZ (1) | NZ589971A (hr) |
PL (1) | PL2119435T3 (hr) |
PT (1) | PT2119435E (hr) |
RU (1) | RU2493834C2 (hr) |
SI (1) | SI2119435T1 (hr) |
UA (1) | UA101035C2 (hr) |
WO (1) | WO2009138517A1 (hr) |
ZA (1) | ZA201009033B (hr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2241351A1 (en) * | 2009-04-16 | 2010-10-20 | Orfagen | Pharmaceutical composition comprising glycerol, white soft paraffin and liquid paraffin for the treatment of uremic xerosis |
FR2957260B1 (fr) * | 2010-03-15 | 2012-04-27 | Fabre Pierre Dermo Cosmetique | Nouvelle formulation dermocorticoide |
CN102488624B (zh) * | 2011-12-13 | 2013-12-04 | 中山市天图精细化工有限公司 | 用于个人护理的凡士林气雾剂组合物 |
EP2845591A1 (en) * | 2013-09-04 | 2015-03-11 | Polichem S.A. | Use of trifluoroacetic acid as keratolytic agent to treat hyperkeratotic skin lesions |
FR3013985B1 (fr) * | 2013-12-03 | 2017-11-03 | Galephar M/F | Compositions hydratantes comprenant au moins un extrait de caesalpinia spinosa, avec au moins de la vaseline et de la glycerine |
DE102013225372A1 (de) * | 2013-12-10 | 2015-06-11 | Henkel Ag & Co. Kgaa | Wärmende Öl-Haarkur |
FR3024360A1 (fr) * | 2014-07-30 | 2016-02-05 | Pf Medicament | Emulsions aux stearates |
FR3090385B1 (fr) | 2018-12-21 | 2021-01-08 | Pf Medicament | Composition émolliente sous forme d’émulsion |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2023786B2 (de) * | 1970-05-15 | 1973-03-01 | Wasser-in-oel-emulgatoren | |
SU925990A1 (ru) * | 1980-06-26 | 1982-05-07 | Уфимский Нефтяной Институт | Способ получени медицинского вазелина |
IL69353A0 (en) * | 1983-07-27 | 1984-01-31 | Berman Daniel | Skin ointment comprising herbal extracts |
PL162396B3 (pl) * | 1989-12-07 | 1993-10-30 | Akademia Medyczna Im Mikolaja | Krem chroniacy skóre przed wodnymi roztworami elektrolitów PL |
US5512278A (en) * | 1994-01-11 | 1996-04-30 | Phylomed Corporation | Ointment base useful for pharmaceutical preparations |
CN1131710C (zh) * | 1997-12-03 | 2003-12-24 | 强生消费者公司 | 皮肤水化能力提高的皮肤护理组合物 |
FR2826659B1 (fr) * | 2001-07-02 | 2005-11-11 | Aldivia | Substitut de lanoline, son procede d'obtention et ses applications |
FR2831443B1 (fr) | 2001-10-30 | 2005-02-11 | Oreal | Utilisation d'extraits vegetaux pour ameliorer la fonction barriere de la peau |
FR2847467B1 (fr) | 2002-11-25 | 2006-05-26 | Oreal | UTILISATION D'UN AGENT MODULATEUR DE L'ACTIVITE DE L'OXYSTEROL 7alpha-HYDROXYLASE POUR LE TRAITEMENT COSMETIQUE DE DESORDRES CUTANES |
CN1552303A (zh) * | 2003-06-03 | 2004-12-08 | 张金铎 | 美白霜及其制备方法 |
CN1927157A (zh) * | 2005-09-08 | 2007-03-14 | 天津市世雄科技发展有限公司 | 夏令驱虫防晒油膏 |
FR2905857B1 (fr) | 2006-09-20 | 2011-02-11 | Chanel Parfums Beaute | Utilisation d'un extrait de pulpe de caroube pour hydrate la peau |
-
2008
- 2008-05-16 FR FR0853187A patent/FR2931073B1/fr active Active
-
2009
- 2009-05-18 EP EP09745849A patent/EP2323639A1/fr not_active Withdrawn
- 2009-05-18 SI SI200930080T patent/SI2119435T1/sl unknown
- 2009-05-18 NZ NZ589971A patent/NZ589971A/xx not_active IP Right Cessation
- 2009-05-18 DK DK09290370.7T patent/DK2119435T3/da active
- 2009-05-18 RU RU2010153201/15A patent/RU2493834C2/ru active
- 2009-05-18 BR BRPI0912506-0A patent/BRPI0912506B1/pt not_active IP Right Cessation
- 2009-05-18 AU AU2009248047A patent/AU2009248047B2/en not_active Ceased
- 2009-05-18 ES ES09290370T patent/ES2370465T3/es active Active
- 2009-05-18 MX MX2010012352A patent/MX2010012352A/es active IP Right Grant
- 2009-05-18 JP JP2011508948A patent/JP5653911B2/ja not_active Expired - Fee Related
- 2009-05-18 PT PT09290370T patent/PT2119435E/pt unknown
- 2009-05-18 AT AT09290370T patent/ATE523192T1/de active
- 2009-05-18 CN CN2009801174703A patent/CN102026632A/zh active Pending
- 2009-05-18 CA CA2724522A patent/CA2724522A1/fr not_active Abandoned
- 2009-05-18 WO PCT/EP2009/056021 patent/WO2009138517A1/fr active Application Filing
- 2009-05-18 CN CN201410366515.3A patent/CN104189005A/zh active Pending
- 2009-05-18 KR KR1020107028152A patent/KR20110023858A/ko not_active Application Discontinuation
- 2009-05-18 UA UAA201015107A patent/UA101035C2/ru unknown
- 2009-05-18 US US12/992,808 patent/US20110071226A1/en not_active Abandoned
- 2009-05-18 PL PL09290370T patent/PL2119435T3/pl unknown
- 2009-05-18 EP EP09290370A patent/EP2119435B1/fr active Active
- 2009-05-18 GE GEAP200912036A patent/GEP20135900B/en unknown
-
2010
- 2010-11-15 IL IL209334A patent/IL209334A/en active IP Right Grant
- 2010-12-15 MA MA33427A patent/MA32396B1/fr unknown
- 2010-12-15 ZA ZA2010/09033A patent/ZA201009033B/en unknown
-
2011
- 2011-07-15 HK HK15104391.0A patent/HK1203828A1/xx unknown
- 2011-12-02 HR HR20110905T patent/HRP20110905T1/hr unknown
- 2011-12-05 CY CY20111101201T patent/CY1112150T1/el unknown
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