HRP20100229T1 - Terapeutski agensi korisni za liječenje boli - Google Patents

Terapeutski agensi korisni za liječenje boli Download PDF

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Publication number
HRP20100229T1
HRP20100229T1 HR20100229T HRP20100229T HRP20100229T1 HR P20100229 T1 HRP20100229 T1 HR P20100229T1 HR 20100229 T HR20100229 T HR 20100229T HR P20100229 T HRP20100229 T HR P20100229T HR P20100229 T1 HRP20100229 T1 HR P20100229T1
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HR
Croatia
Prior art keywords
compound according
phenyl
halo
alkyl
substituted
Prior art date
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HR20100229T
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English (en)
Croatian (hr)
Inventor
J. Kyle Donald
Sun Qun
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Euro-Celtique S.A.
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Publication date
Application filed by Euro-Celtique S.A. filed Critical Euro-Celtique S.A.
Publication of HRP20100229T1 publication Critical patent/HRP20100229T1/hr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3
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HK1120799A1 (en) 2009-04-09
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ATE455773T1 (de) 2010-02-15
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MXPA06001331A (es) 2006-05-04
DE602004025244D1 (de) 2010-03-11
PT1942106E (pt) 2011-12-22
CY1110004T1 (el) 2015-01-14
DK1942106T3 (da) 2011-12-19
DK1648880T3 (da) 2010-05-10
ATE524455T1 (de) 2011-09-15
EP1942106A1 (en) 2008-07-09
US20060258669A1 (en) 2006-11-16
HK1093489A1 (en) 2007-03-02
HRP20110891T1 (hr) 2011-12-31
EP1648880A1 (en) 2006-04-26
WO2005012287A1 (en) 2005-02-10
PT1648880E (pt) 2010-04-26
CN1832935A (zh) 2006-09-13
EP2275420A1 (en) 2011-01-19
US8030310B2 (en) 2011-10-04
SI1942106T1 (sl) 2012-01-31
EP1648880B1 (en) 2010-01-20
JP2007501240A (ja) 2007-01-25
ES2374017T3 (es) 2012-02-13
AU2004261666A1 (en) 2005-02-10
ES2340168T3 (es) 2010-05-31
US20100240675A1 (en) 2010-09-23
JP5148110B2 (ja) 2013-02-20
CA2534088A1 (en) 2005-02-10
US7696208B2 (en) 2010-04-13
CA2534088C (en) 2011-01-11
AU2004261666B2 (en) 2009-06-18
CY1112129T1 (el) 2015-11-04
PL1648880T3 (pl) 2010-06-30

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