HRP20090412T1 - 3-(2-(dimetlamino)metil-(cikloheks-1-il))fenol-maleat i njegovi kristalni oblici - Google Patents

3-(2-(dimetlamino)metil-(cikloheks-1-il))fenol-maleat i njegovi kristalni oblici Download PDF

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Publication number
HRP20090412T1
HRP20090412T1 HR20090412T HRP20090412T HRP20090412T1 HR P20090412 T1 HRP20090412 T1 HR P20090412T1 HR 20090412 T HR20090412 T HR 20090412T HR P20090412 T HRP20090412 T HR P20090412T HR P20090412 T1 HRP20090412 T1 HR P20090412T1
Authority
HR
Croatia
Prior art keywords
salt
present
crystalline form
cyclohex
dimethylamino
Prior art date
Application number
HR20090412T
Other languages
English (en)
Croatian (hr)
Inventor
Szelagiewicz Martin
Hell Wolfgang
Von Raumer Markus
Margaret De Paul Susan
Berghausen J�rg
Gruss Michael
Original Assignee
Grnenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grnenthal Gmbh filed Critical Grnenthal Gmbh
Publication of HRP20090412T1 publication Critical patent/HRP20090412T1/hr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
HR20090412T 2005-07-22 2006-07-20 3-(2-(dimetlamino)metil-(cikloheks-1-il))fenol-maleat i njegovi kristalni oblici HRP20090412T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005034974A DE102005034974A1 (de) 2005-07-22 2005-07-22 Salz von Dimethylaminomethyl-phenyl-cyclohexan und dessen kristalline Formen
PCT/EP2006/007160 WO2007009792A1 (de) 2005-07-22 2006-07-20 3-(2-(dimethylamino)methyl-(cyclohex-1-yl))phenol-maleat und dessen kristalline formen

Publications (1)

Publication Number Publication Date
HRP20090412T1 true HRP20090412T1 (hr) 2009-09-30

Family

ID=37084866

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20090412T HRP20090412T1 (hr) 2005-07-22 2006-07-20 3-(2-(dimetlamino)metil-(cikloheks-1-il))fenol-maleat i njegovi kristalni oblici

Country Status (25)

Country Link
EP (1) EP1881956B1 (https=)
JP (1) JP5205259B2 (https=)
KR (1) KR20080033436A (https=)
CN (1) CN101228110A (https=)
AR (1) AR057674A1 (https=)
AT (1) ATE431332T1 (https=)
AU (1) AU2006271856B2 (https=)
BR (1) BRPI0614057A2 (https=)
CA (1) CA2615926A1 (https=)
CY (1) CY1109208T1 (https=)
DE (2) DE102005034974A1 (https=)
DK (1) DK1881956T3 (https=)
EC (1) ECSP088088A (https=)
ES (1) ES2326493T3 (https=)
HR (1) HRP20090412T1 (https=)
IL (1) IL188897A (https=)
MX (1) MX2008000743A (https=)
NO (1) NO20080826L (https=)
PE (1) PE20070368A1 (https=)
PL (1) PL1881956T3 (https=)
PT (1) PT1881956E (https=)
RU (1) RU2434845C2 (https=)
SI (1) SI1881956T1 (https=)
WO (1) WO2007009792A1 (https=)
ZA (1) ZA200801703B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2008000070A1 (es) * 2007-01-17 2008-07-25 Lg Life Sciences Ltd Monosal del acido maleico (3-[({1-[(2-amino-9h-purin-9-il)metil]ciclopropil}oxi)metil]-8,8-dimetil-3,7-dioxo-2,4,6-trioxa-3 lambda 5-fosfanon-1-il-pivalato; composicion farmaceutica que comprende a dicha monosal; y uso para el tratamiento del virus h
CN104447360B (zh) * 2007-12-07 2017-04-12 格吕伦塔尔有限公司 (1r,2r)‑3‑(3‑二甲基氨基‑1‑乙基‑2‑甲基‑丙基)‑苯酚的结晶变体
EP2085081A1 (de) 2008-02-04 2009-08-05 Grünenthal GmbH 3-(2-Dimethylaminomethyl-cyclohexyl)-phenol gegen polyneuropathischen Schmerz

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19525137C2 (de) * 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
DE10218862A1 (de) * 2002-04-26 2003-11-06 Gruenenthal Gmbh Verfahren zur Chlorierung tertiärer Alkohole
DE10356362A1 (de) * 2003-11-28 2005-06-23 Grünenthal GmbH Verwendung von 1-Phenyl-3-dimethylamino-propanverbindungen zur Therapie von Angststörungen

Also Published As

Publication number Publication date
ES2326493T3 (es) 2009-10-13
AR057674A1 (es) 2007-12-12
RU2008106455A (ru) 2009-08-27
CA2615926A1 (en) 2007-01-25
HK1112612A1 (zh) 2008-09-12
PT1881956E (pt) 2009-06-26
MX2008000743A (es) 2008-03-10
DE102005034974A1 (de) 2007-04-19
AU2006271856A1 (en) 2007-01-25
SI1881956T1 (sl) 2009-10-31
NO20080826L (no) 2008-02-20
EP1881956B1 (de) 2009-05-13
IL188897A (en) 2012-12-31
CN101228110A (zh) 2008-07-23
ATE431332T1 (de) 2009-05-15
RU2434845C2 (ru) 2011-11-27
KR20080033436A (ko) 2008-04-16
DE502006003728D1 (de) 2009-06-25
JP5205259B2 (ja) 2013-06-05
PE20070368A1 (es) 2007-05-12
JP2009502757A (ja) 2009-01-29
CY1109208T1 (el) 2014-07-02
WO2007009792A1 (de) 2007-01-25
AU2006271856B2 (en) 2012-03-01
IL188897A0 (en) 2008-04-13
BRPI0614057A2 (pt) 2012-12-11
PL1881956T3 (pl) 2009-10-30
DK1881956T3 (da) 2009-09-07
ZA200801703B (en) 2009-08-26
ECSP088088A (es) 2008-02-20
EP1881956A1 (de) 2008-01-30

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