HRP20070574T3 - Antimikobakterijski farmaceutski sastav koji sadrži lijek protiv tuberkoloze - Google Patents
Antimikobakterijski farmaceutski sastav koji sadrži lijek protiv tuberkolozeInfo
- Publication number
- HRP20070574T3 HRP20070574T3 HR20070574T HRP20070574T HRP20070574T3 HR P20070574 T3 HRP20070574 T3 HR P20070574T3 HR 20070574 T HR20070574 T HR 20070574T HR P20070574 T HRP20070574 T HR P20070574T HR P20070574 T3 HRP20070574 T3 HR P20070574T3
- Authority
- HR
- Croatia
- Prior art keywords
- pharmaceutical composition
- antimycobacterial
- antitubercular drug
- antimycobacterial pharmaceutical
- methyl
- Prior art date
Links
- 230000001355 anti-mycobacterial effect Effects 0.000 title abstract 2
- 239000003926 antimycobacterial agent Substances 0.000 title abstract 2
- 229940124976 antitubercular drug Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- PRXZOPNJRFEGRH-UHFFFAOYSA-N n-[2-methyl-5-phenyl-3-[[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methyl]pyrrol-1-yl]pyridine-4-carboxamide Chemical compound C1=C(C=2C=CC=CC=2)N(NC(=O)C=2C=CN=CC=2)C(C)=C1CN(CC1)CCN1C1=CC=CC(C(F)(F)F)=C1 PRXZOPNJRFEGRH-UHFFFAOYSA-N 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 229960005206 pyrazinamide Drugs 0.000 abstract 1
- IPEHBUMCGVEMRF-UHFFFAOYSA-N pyrazinecarboxamide Chemical compound NC(=O)C1=CN=CC=N1 IPEHBUMCGVEMRF-UHFFFAOYSA-N 0.000 abstract 1
- JQXXHWHPUNPDRT-WLSIYKJHSA-N rifampicin Chemical compound O([C@](C1=O)(C)O/C=C/[C@@H]([C@H]([C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)\C=C\C=C(C)/C(=O)NC=2C(O)=C3C([O-])=C4C)C)OC)C4=C1C3=C(O)C=2\C=N\N1CC[NH+](C)CC1 JQXXHWHPUNPDRT-WLSIYKJHSA-N 0.000 abstract 1
- 229960001225 rifampicin Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/131—Amines acyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/49—Cinchonan derivatives, e.g. quinine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Antimikobakterijska kombinacija koja sadržava terapeutski djelotvornu količinu N-(3-[[4-(3-trifluormetilfenil)piperazinil]metil]-2-metil-5fenil-pirolil)-4-piridilkarboksamida ili njegove farmaceutskiprihvatljive netoksične solii terapeutski djelotvornu količinu jednog ili više antituberkulotika izprve linije odabranih iz grupe koja se sastoji odisoniazida, rifampicina, itambutola i pirazinamida. Patent sadrži još 22 patentna zahtjeva.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/844,992 US7491721B2 (en) | 2004-05-12 | 2004-05-12 | Antimycobacterial pharmaceutical composition |
| PCT/IN2004/000266 WO2005107809A2 (en) | 2004-05-12 | 2004-08-27 | Antimycobacterial pharmaceutical composition comprising an antitubercular drug |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20070574T3 true HRP20070574T3 (hr) | 2008-01-31 |
Family
ID=34960626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20070574T HRP20070574T3 (hr) | 2004-05-12 | 2007-12-19 | Antimikobakterijski farmaceutski sastav koji sadrži lijek protiv tuberkoloze |
Country Status (45)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006233943A1 (en) * | 2005-04-11 | 2006-10-19 | Lupin Limited | Preparation of (2-methyl-5-phenyl-3-(piperazin-1-ylmethyl)) pyrrole derivatives |
| JP5339840B2 (ja) * | 2008-10-02 | 2013-11-13 | 公益財団法人微生物化学研究会 | 抗ｘｄｒ−ｔｂ薬、抗ｍｄｒ−ｔｂ薬、及び併用抗結核薬 |
| US9198913B2 (en) * | 2009-07-31 | 2015-12-01 | Global Alliance For Tb Drug Development | Nitroimidazooxazines and their uses in anti-tubercular therapy |
| AU2010292148A1 (en) * | 2009-09-11 | 2012-04-12 | Vertex Pharmaceuticals Incorporated | Compositions of N-benzyl-3-(4-chlorophenyl)-2- [methyl-[2-oxo-2-(3,4,5-trimethoxyphenyl) acetyl]amino]-N- [3-(4-pyridyl)-1-[2-[4-pyridyl)ethy]propyl]propanamide and uses thereof |
| HUP1000033A2 (en) * | 2010-01-21 | 2011-07-28 | Uratim Kft | Piperazine derivatives useful against mycobacteriums |
| KR102462751B1 (ko) * | 2021-10-20 | 2022-11-03 | 순천향대학교 산학협력단 | 신규한 페디오코커스 균주 및 이를 포함하는 결핵 예방, 치료, 또는 개선용 조성물 |
| US11977085B1 (en) | 2023-09-05 | 2024-05-07 | Elan Ehrlich | Date rape drug detection device and method of using same |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5227383A (en) * | 1991-06-14 | 1993-07-13 | The University Of Mississippi | Compounds and compositions useful as antifungal and antimycobacterial agents |
| RS20050231A (en) * | 2002-09-20 | 2007-06-04 | Lupin Limited, | Pyrrole derivatives as antimycobacterial compounds |
-
2004
- 2004-05-12 US US10/844,992 patent/US7491721B2/en not_active Expired - Fee Related
- 2004-08-27 CN CN2004800431312A patent/CN1956732B/zh not_active Expired - Fee Related
- 2004-08-27 RS YUP-2006/0624A patent/RS20060624A/sr unknown
- 2004-08-27 DE DE602004009113T patent/DE602004009113T2/de active Active
- 2004-08-27 GE GEAP20049749A patent/GEP20094805B/en unknown
- 2004-08-27 AT AT04816650T patent/ATE373488T1/de active
- 2004-08-27 KR KR1020067023513A patent/KR100854309B1/ko not_active IP Right Cessation
- 2004-08-27 EA EA200601952A patent/EA009694B1/ru not_active IP Right Cessation
- 2004-08-27 UA UAA200612258A patent/UA82782C2/uk unknown
- 2004-08-27 CA CA002566440A patent/CA2566440C/en not_active Expired - Fee Related
- 2004-08-27 MX MXPA06012984A patent/MXPA06012984A/es active IP Right Grant
- 2004-08-27 EP EP04816650A patent/EP1750765B1/en active Active
- 2004-08-27 ES ES04816650T patent/ES2294577T3/es active Active
- 2004-08-27 SI SI200430552T patent/SI1750765T1/sl unknown
- 2004-08-27 BR BRPI0418770-9A patent/BRPI0418770A/pt not_active IP Right Cessation
- 2004-08-27 DK DK04816650T patent/DK1750765T3/da active
- 2004-08-27 PL PL04816650T patent/PL1750765T3/pl unknown
- 2004-08-27 WO PCT/IN2004/000266 patent/WO2005107809A2/en active IP Right Grant
- 2004-08-27 PT PT04816650T patent/PT1750765E/pt unknown
- 2004-08-27 AP AP2006003807A patent/AP1994A/xx active
- 2004-08-27 NZ NZ550892A patent/NZ550892A/en unknown
- 2004-08-27 AU AU2004319259A patent/AU2004319259A1/en not_active Abandoned
- 2004-08-27 JP JP2007512723A patent/JP2007537242A/ja active Pending
-
2005
- 2005-05-11 SV SV2005002109A patent/SV2006002109A/es not_active Application Discontinuation
- 2005-05-11 AR ARP050101898A patent/AR048948A1/es not_active Application Discontinuation
- 2005-05-11 MY MYPI20052107A patent/MY139187A/en unknown
- 2005-05-11 DO DO2005000085A patent/DOP2005000085A/es unknown
- 2005-05-11 UY UY28893A patent/UY28893A1/es unknown
- 2005-05-11 PE PE2005000526A patent/PE20060353A1/es not_active Application Discontinuation
- 2005-05-12 HN HN2005000210A patent/HN2005000210A/es unknown
- 2005-05-12 JO JO200559A patent/JO2471B1/en active
- 2005-05-12 SM SM200500011A patent/SM200500011B/it unknown
- 2005-05-12 PA PA20058633001A patent/PA8633001A1/es unknown
- 2005-05-14 SA SA5260130A patent/SA05260130B1/ar unknown
-
2006
- 2006-10-24 ZA ZA200608843A patent/ZA200608843B/xx unknown
- 2006-10-25 IL IL178858A patent/IL178858A/en not_active IP Right Cessation
- 2006-10-26 IS IS8559A patent/IS8559A/is unknown
- 2006-10-30 TN TNP2006000349A patent/TNSN06349A1/en unknown
- 2006-10-30 EC EC2006006965A patent/ECSP066965A/es unknown
- 2006-11-10 CR CR8748A patent/CR8748A/es not_active Application Discontinuation
- 2006-11-10 NI NI200600270A patent/NI200600270A/es unknown
- 2006-11-23 MA MA29484A patent/MA28603B1/fr unknown
- 2006-12-12 NO NO20065725A patent/NO20065725L/no not_active Application Discontinuation
-
2007
- 2007-06-14 HK HK07106405A patent/HK1098962A1/xx not_active IP Right Cessation
- 2007-12-19 HR HR20070574T patent/HRP20070574T3/hr unknown
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