HRP20070524T3 - CINNAMATES OF BENZO[b]PYRANO[3,2-h]ACRIDIN-7-ONE, PROCESS FOR PREPARATION THEREOF AND THEIR PHARMACEUTICAL COMPOSITION - Google Patents
CINNAMATES OF BENZO[b]PYRANO[3,2-h]ACRIDIN-7-ONE, PROCESS FOR PREPARATION THEREOF AND THEIR PHARMACEUTICAL COMPOSITIONInfo
- Publication number
- HRP20070524T3 HRP20070524T3 HR20070524T HRP20070524T HRP20070524T3 HR P20070524 T3 HRP20070524 T3 HR P20070524T3 HR 20070524 T HR20070524 T HR 20070524T HR P20070524 T HRP20070524 T HR P20070524T HR P20070524 T3 HRP20070524 T3 HR P20070524T3
- Authority
- HR
- Croatia
- Prior art keywords
- alkyl
- aryl
- optionally substituted
- halo
- aar
- Prior art date
Links
- MKZZLOWSEULQCH-UHFFFAOYSA-N 8-oxa-2-azapentacyclo[12.8.0.03,12.04,9.016,21]docosa-1(22),2,4,6,9,11,14,16,18,20-decaen-13-one Chemical compound C1=COC2=CC=C3C(=O)C4=CC5=CC=CC=C5C=C4N=C3C2=C1 MKZZLOWSEULQCH-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 13
- 125000003118 aryl group Chemical group 0.000 abstract 7
- 125000005843 halogen group Chemical group 0.000 abstract 6
- -1 acridin-7-one cinnamate compounds Chemical class 0.000 abstract 4
- 125000005842 heteroatom Chemical group 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 239000002585 base Substances 0.000 abstract 2
- 125000005605 benzo group Chemical group 0.000 abstract 2
- 150000004677 hydrates Chemical class 0.000 abstract 2
- 125000002950 monocyclic group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000012453 solvate Substances 0.000 abstract 2
- 229910003827 NRaRb Inorganic materials 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000005196 alkyl carbonyloxy group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 239000000824 cytostatic agent Substances 0.000 abstract 1
- 230000001085 cytostatic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0413682A FR2879600B1 (fr) | 2004-12-22 | 2004-12-22 | Nouveaux derives cinnamates de benzo[b]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20070524T3 true HRP20070524T3 (en) | 2008-07-31 |
Family
ID=34954114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20070524T HRP20070524T3 (en) | 2004-12-22 | 2007-11-15 | CINNAMATES OF BENZO[b]PYRANO[3,2-h]ACRIDIN-7-ONE, PROCESS FOR PREPARATION THEREOF AND THEIR PHARMACEUTICAL COMPOSITION |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US7144891B2 (zh) |
| EP (1) | EP1674101B1 (zh) |
| JP (1) | JP2006176525A (zh) |
| KR (1) | KR100742060B1 (zh) |
| CN (1) | CN1796387A (zh) |
| AT (1) | ATE378050T1 (zh) |
| AU (1) | AU2005247032A1 (zh) |
| BR (1) | BRPI0506019A (zh) |
| CA (1) | CA2529630A1 (zh) |
| CY (1) | CY1107100T1 (zh) |
| DE (1) | DE602005003315T2 (zh) |
| DK (1) | DK1674101T3 (zh) |
| EA (1) | EA010094B1 (zh) |
| ES (1) | ES2297648T3 (zh) |
| FR (1) | FR2879600B1 (zh) |
| HR (1) | HRP20070524T3 (zh) |
| MA (1) | MA27965A1 (zh) |
| MX (1) | MXPA05013993A (zh) |
| MY (1) | MY138045A (zh) |
| NO (1) | NO20056091L (zh) |
| NZ (1) | NZ544315A (zh) |
| PL (1) | PL1674101T3 (zh) |
| PT (1) | PT1674101E (zh) |
| SG (1) | SG123675A1 (zh) |
| SI (1) | SI1674101T1 (zh) |
| ZA (1) | ZA200510323B (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2902792A1 (fr) * | 2006-06-21 | 2007-12-28 | Servier Lab | Nouveaux derives cinnamates de tetrahydro-7h-pyrano(2,3-c)acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2772765B1 (fr) * | 1997-12-19 | 2000-03-17 | Adir | Nouveaux derives de l'acronycine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2795071B1 (fr) * | 1999-06-16 | 2001-07-27 | Adir | Nouveaux derives de carboxylate de 7-oxo-2,3,7,14- tetrahydro-1h-benzo[b]pyrano[3,2,h] acridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US7056929B2 (en) * | 2001-07-25 | 2006-06-06 | Les Laboratoires Servier | Benzo[b]pyrano[3,2-h]acridin-7-one compounds |
| FR2827864B1 (fr) * | 2001-07-25 | 2005-09-16 | Servier Lab | Nouveaux derives de benzo[b]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2004
- 2004-12-22 FR FR0413682A patent/FR2879600B1/fr not_active Expired - Fee Related
-
2005
- 2005-12-01 SG SG200507683A patent/SG123675A1/en unknown
- 2005-12-07 MA MA28637A patent/MA27965A1/fr unknown
- 2005-12-09 CA CA002529630A patent/CA2529630A1/fr not_active Abandoned
- 2005-12-20 MX MXPA05013993A patent/MXPA05013993A/es unknown
- 2005-12-20 ZA ZA200510323A patent/ZA200510323B/en unknown
- 2005-12-20 MY MYPI20056024A patent/MY138045A/en unknown
- 2005-12-21 AT AT05292744T patent/ATE378050T1/de not_active IP Right Cessation
- 2005-12-21 EP EP05292744A patent/EP1674101B1/fr active Active
- 2005-12-21 NO NO20056091A patent/NO20056091L/no not_active Application Discontinuation
- 2005-12-21 DE DE602005003315T patent/DE602005003315T2/de not_active Expired - Fee Related
- 2005-12-21 SI SI200530108T patent/SI1674101T1/sl unknown
- 2005-12-21 PT PT05292744T patent/PT1674101E/pt unknown
- 2005-12-21 US US11/313,386 patent/US7144891B2/en not_active Expired - Fee Related
- 2005-12-21 DK DK05292744T patent/DK1674101T3/da active
- 2005-12-21 EA EA200501845A patent/EA010094B1/ru unknown
- 2005-12-21 ES ES05292744T patent/ES2297648T3/es active Active
- 2005-12-21 NZ NZ544315A patent/NZ544315A/en unknown
- 2005-12-21 PL PL05292744T patent/PL1674101T3/pl unknown
- 2005-12-22 CN CNA2005101328156A patent/CN1796387A/zh active Pending
- 2005-12-22 KR KR1020050128012A patent/KR100742060B1/ko not_active IP Right Cessation
- 2005-12-22 JP JP2005369129A patent/JP2006176525A/ja active Pending
- 2005-12-22 BR BRPI0506019-2A patent/BRPI0506019A/pt not_active IP Right Cessation
- 2005-12-22 AU AU2005247032A patent/AU2005247032A1/en not_active Abandoned
-
2007
- 2007-11-15 HR HR20070524T patent/HRP20070524T3/xx unknown
- 2007-12-19 CY CY20071101611T patent/CY1107100T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005003315D1 (de) | 2007-12-27 |
| CA2529630A1 (fr) | 2006-06-22 |
| PL1674101T3 (pl) | 2008-05-30 |
| MA27965A1 (fr) | 2006-07-03 |
| CN1796387A (zh) | 2006-07-05 |
| EA010094B1 (ru) | 2008-06-30 |
| NO20056091L (no) | 2006-06-23 |
| US7144891B2 (en) | 2006-12-05 |
| EA200501845A3 (ru) | 2006-10-27 |
| MXPA05013993A (es) | 2006-06-21 |
| EA200501845A2 (ru) | 2006-06-30 |
| DE602005003315T2 (de) | 2008-09-25 |
| ZA200510323B (en) | 2006-12-27 |
| SI1674101T1 (sl) | 2008-04-30 |
| PT1674101E (pt) | 2007-12-17 |
| KR100742060B1 (ko) | 2007-07-23 |
| SG123675A1 (en) | 2006-07-26 |
| ATE378050T1 (de) | 2007-11-15 |
| JP2006176525A (ja) | 2006-07-06 |
| AU2005247032A1 (en) | 2006-07-06 |
| EP1674101B1 (fr) | 2007-11-14 |
| MY138045A (en) | 2009-04-30 |
| FR2879600A1 (fr) | 2006-06-23 |
| US20060135545A1 (en) | 2006-06-22 |
| FR2879600B1 (fr) | 2007-02-09 |
| KR20060072093A (ko) | 2006-06-27 |
| ES2297648T3 (es) | 2008-05-01 |
| NZ544315A (en) | 2006-11-30 |
| EP1674101A1 (fr) | 2006-06-28 |
| DK1674101T3 (da) | 2008-03-03 |
| CY1107100T1 (el) | 2012-10-24 |
| BRPI0506019A (pt) | 2006-09-19 |
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