HRP20040742B1 - Stable salts of o-acetylsalicylic acid containing basic amino acids ii - Google Patents
Stable salts of o-acetylsalicylic acid containing basic amino acids iiInfo
- Publication number
- HRP20040742B1 HRP20040742B1 HR20040742A HRP20040742A HRP20040742B1 HR P20040742 B1 HRP20040742 B1 HR P20040742B1 HR 20040742 A HR20040742 A HR 20040742A HR P20040742 A HRP20040742 A HR P20040742A HR P20040742 B1 HRP20040742 B1 HR P20040742B1
- Authority
- HR
- Croatia
- Prior art keywords
- basic amino
- acetylsalicylic acid
- amino acids
- acid containing
- containing basic
- Prior art date
Links
- 150000001413 amino acids Chemical class 0.000 title abstract 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical class CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 3
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract 1
- UQJRAOCVSMOMNW-UHFFFAOYSA-N acetyl 2-hydroxybenzoate Chemical class CC(=O)OC(=O)C1=CC=CC=C1O UQJRAOCVSMOMNW-UHFFFAOYSA-N 0.000 abstract 1
- 238000007908 dry granulation Methods 0.000 abstract 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract 1
- 239000008108 microcrystalline cellulose Substances 0.000 abstract 1
- 229940016286 microcrystalline cellulose Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10202019A DE10202019A1 (de) | 2002-01-18 | 2002-01-18 | Stabile Salze von o-Acetylsalicylsäure mit basischen Aminosäuren II |
| PCT/EP2003/000059 WO2003059323A2 (de) | 2002-01-18 | 2003-01-07 | Stabile salze von o-acetylsalicylsäure mit basischen aminosäuren ii |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP20040742A2 HRP20040742A2 (en) | 2005-08-31 |
| HRP20040742B1 true HRP20040742B1 (en) | 2008-05-31 |
Family
ID=7712593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20040742A HRP20040742B1 (en) | 2002-01-18 | 2004-08-17 | Stable salts of o-acetylsalicylic acid containing basic amino acids ii |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US20050171070A1 (sr) |
| EP (1) | EP1469835B1 (sr) |
| JP (1) | JP2005519892A (sr) |
| KR (1) | KR20040079936A (sr) |
| CN (1) | CN1298314C (sr) |
| AR (1) | AR038298A1 (sr) |
| AT (1) | ATE378040T1 (sr) |
| AU (1) | AU2003235700B2 (sr) |
| BR (1) | BR0307009A (sr) |
| CA (1) | CA2473893A1 (sr) |
| CO (1) | CO5611102A2 (sr) |
| CU (1) | CU20040161A7 (sr) |
| DE (2) | DE10202019A1 (sr) |
| EC (1) | ECSP045192A (sr) |
| ES (1) | ES2297166T3 (sr) |
| GT (1) | GT200300004A (sr) |
| HK (1) | HK1080371A1 (sr) |
| HN (1) | HN2003000015A (sr) |
| HR (1) | HRP20040742B1 (sr) |
| IL (1) | IL162881A0 (sr) |
| MX (1) | MXPA04006832A (sr) |
| NO (1) | NO20043404L (sr) |
| NZ (1) | NZ534128A (sr) |
| PE (1) | PE20030731A1 (sr) |
| PL (1) | PL370197A1 (sr) |
| RS (1) | RS63804A (sr) |
| SV (1) | SV2004001457A (sr) |
| TW (1) | TWI265810B (sr) |
| UY (1) | UY27612A1 (sr) |
| WO (1) | WO2003059323A2 (sr) |
| ZA (1) | ZA200405533B (sr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004025535A1 (de) * | 2004-05-25 | 2005-12-22 | Bayer Healthcare Ag | Kombination von Salzen der o-Acetylsalicylsäure und Alpha-Glucosidase-Inhibitoren |
| DE102005025283A1 (de) * | 2005-06-02 | 2006-12-07 | Bayer Healthcare Ag | Stabiler Wirkstoffkomplex von Salzen der o-Acetylsalicylsäure mit basischen Aminosäuren und Glycin |
| DE102005049293A1 (de) * | 2005-10-15 | 2007-04-26 | Bayer Healthcare Ag | Kombinationspräparate von Salzen oder o-Acetylsalicylsäure |
| DE102008004386A1 (de) | 2008-01-14 | 2009-07-23 | Activaero Gmbh | Verwendung eines Acetylsalicylsäuresalzes zur Behandlung viraler Infektionen |
| JP5309977B2 (ja) * | 2008-12-26 | 2013-10-09 | ライオン株式会社 | チュアブル錠 |
| US8173625B2 (en) * | 2009-05-08 | 2012-05-08 | Theaprin Pharmaceuticals Inc. | Intravenous formulation with water-soluble cocrystals of acetylsalicylic acid and theanine |
| BRPI1009600A2 (sr) * | 2009-06-25 | 2016-03-22 | Tetra S A | |
| JP5563835B2 (ja) * | 2010-01-15 | 2014-07-30 | 全星薬品工業株式会社 | アスピリン錠剤の製造方法 |
| ITMI20121144A1 (it) * | 2012-06-28 | 2013-12-29 | Dipharma Francis Srl | Procedimento per la preparazione di un sale di un farmaco antinfiammatorio non steroideo |
| AU2017383071B2 (en) | 2016-12-23 | 2021-04-29 | Aspiair Gmbh | Improved synthesis of lysine acetylsalicylate · glycine particles |
| RU2738831C1 (ru) * | 2020-03-03 | 2020-12-17 | федеральное государственное бюджетное образовательное учреждение высшего образования "Ростовский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО РостГМУ Минздрава России) | Способ консервативного лечения невралгии тройничного нерва |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4265888A (en) * | 1979-07-06 | 1981-05-05 | The Green Cross Corporation | Acetylsalicylate powder preparation for injection |
| US4988683A (en) * | 1987-03-04 | 1991-01-29 | Jerome Corbiere | New pharmaceutical compositions for the buccal tract and process for their preparation |
| WO2002005782A2 (de) * | 2000-07-18 | 2002-01-24 | Bayer Aktiengesellschaft | Stabile salze von o-acetylsalicylsäure mit basischen aminosäuren |
-
2002
- 2002-01-18 DE DE10202019A patent/DE10202019A1/de not_active Withdrawn
-
2003
- 2003-01-07 PL PL03370197A patent/PL370197A1/xx not_active Application Discontinuation
- 2003-01-07 CN CNB038064154A patent/CN1298314C/zh not_active Expired - Fee Related
- 2003-01-07 KR KR10-2004-7011078A patent/KR20040079936A/ko not_active Application Discontinuation
- 2003-01-07 RS YU63804A patent/RS63804A/sr unknown
- 2003-01-07 NZ NZ534128A patent/NZ534128A/en not_active IP Right Cessation
- 2003-01-07 BR BR0307009-3A patent/BR0307009A/pt not_active IP Right Cessation
- 2003-01-07 MX MXPA04006832A patent/MXPA04006832A/es active IP Right Grant
- 2003-01-07 AU AU2003235700A patent/AU2003235700B2/en not_active Ceased
- 2003-01-07 JP JP2003559486A patent/JP2005519892A/ja active Pending
- 2003-01-07 DE DE50308596T patent/DE50308596D1/de not_active Expired - Lifetime
- 2003-01-07 US US10/501,677 patent/US20050171070A1/en not_active Abandoned
- 2003-01-07 WO PCT/EP2003/000059 patent/WO2003059323A2/de active IP Right Grant
- 2003-01-07 CA CA002473893A patent/CA2473893A1/en not_active Abandoned
- 2003-01-07 AT AT03729426T patent/ATE378040T1/de not_active IP Right Cessation
- 2003-01-07 EP EP03729426A patent/EP1469835B1/de not_active Expired - Lifetime
- 2003-01-07 IL IL16288103A patent/IL162881A0/xx unknown
- 2003-01-07 ES ES03729426T patent/ES2297166T3/es not_active Expired - Lifetime
- 2003-01-14 GT GT200300004A patent/GT200300004A/es unknown
- 2003-01-15 UY UY27612A patent/UY27612A1/es not_active Application Discontinuation
- 2003-01-16 AR ARP030100121A patent/AR038298A1/es not_active Application Discontinuation
- 2003-01-17 HN HN2003000015A patent/HN2003000015A/es unknown
- 2003-01-17 PE PE2003000052A patent/PE20030731A1/es not_active Application Discontinuation
- 2003-01-17 SV SV2003001457A patent/SV2004001457A/es unknown
- 2003-01-17 TW TW092100932A patent/TWI265810B/zh not_active IP Right Cessation
-
2004
- 2004-07-13 ZA ZA200405533A patent/ZA200405533B/en unknown
- 2004-07-15 EC EC2004005192A patent/ECSP045192A/es unknown
- 2004-07-19 CU CU20040161A patent/CU20040161A7/es unknown
- 2004-08-16 NO NO20043404A patent/NO20043404L/no not_active Application Discontinuation
- 2004-08-17 HR HR20040742A patent/HRP20040742B1/xx not_active IP Right Cessation
- 2004-08-17 CO CO04079945A patent/CO5611102A2/es not_active Application Discontinuation
-
2006
- 2006-01-06 HK HK06100280A patent/HK1080371A1/xx not_active IP Right Cessation
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4265888A (en) * | 1979-07-06 | 1981-05-05 | The Green Cross Corporation | Acetylsalicylate powder preparation for injection |
| US4988683A (en) * | 1987-03-04 | 1991-01-29 | Jerome Corbiere | New pharmaceutical compositions for the buccal tract and process for their preparation |
| WO2002005782A2 (de) * | 2000-07-18 | 2002-01-24 | Bayer Aktiengesellschaft | Stabile salze von o-acetylsalicylsäure mit basischen aminosäuren |
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| Date | Code | Title | Description |
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| A1OB | Publication of a patent application | ||
| AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
| B1PR | Patent granted | ||
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20091231 Year of fee payment: 8 |
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| PPPP | Transfer of rights |
Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT, DE |
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| PBON | Lapse due to non-payment of renewal fee |
Effective date: 20110108 |