HRP20031090A2 - Imidazotriazinones derivatives and their use against inflammatory processes and/or immune diseases - Google Patents

Imidazotriazinones derivatives and their use against inflammatory processes and/or immune diseases Download PDF

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Publication number
HRP20031090A2
HRP20031090A2 HR20031090A HRP20031090A HRP20031090A2 HR P20031090 A2 HRP20031090 A2 HR P20031090A2 HR 20031090 A HR20031090 A HR 20031090A HR P20031090 A HRP20031090 A HR P20031090A HR P20031090 A2 HRP20031090 A2 HR P20031090A2
Authority
HR
Croatia
Prior art keywords
mmol
image
compounds
tert
yield
Prior art date
Application number
HR20031090A
Other languages
English (en)
Croatian (hr)
Inventor
Alonso-Alija Cristina
Gielen Heike
Hendrix Martin
Theresia Niew�hner Maria
Schauss Dagmar
Bischoff Hilmar
Burkhardt Nils
Geiss Volker
Schlemmer Karl-Heinz
J. Cuthbert Nigel
Fitzgerald Mary
Sturton Graham
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Publication of HRP20031090A2 publication Critical patent/HRP20031090A2/hr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D253/00Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/061,2,4-Triazines
    • C07D253/0651,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/071,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HR20031090A 2001-06-01 2003-12-29 Imidazotriazinones derivatives and their use against inflammatory processes and/or immune diseases HRP20031090A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0113344.6A GB0113344D0 (en) 2001-06-01 2001-06-01 Novel heterocycles 3
PCT/EP2002/005436 WO2002098879A1 (en) 2001-06-01 2002-05-17 Imidazotriazinones derivatives and their use against inflammatory processes and/or immune diseases

Publications (1)

Publication Number Publication Date
HRP20031090A2 true HRP20031090A2 (en) 2005-08-31

Family

ID=9915717

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20031090A HRP20031090A2 (en) 2001-06-01 2003-12-29 Imidazotriazinones derivatives and their use against inflammatory processes and/or immune diseases

Country Status (28)

Country Link
US (2) US7115602B2 (no)
EP (1) EP1399447A1 (no)
JP (1) JP2004536078A (no)
KR (1) KR20040023605A (no)
CN (1) CN1512993A (no)
BG (1) BG108381A (no)
BR (1) BR0210910A (no)
CA (1) CA2449095A1 (no)
CO (1) CO5540381A2 (no)
CZ (1) CZ295609B6 (no)
EC (1) ECSP034872A (no)
EE (1) EE200300570A (no)
GB (1) GB0113344D0 (no)
GT (1) GT200200099A (no)
HR (1) HRP20031090A2 (no)
HU (1) HUP0400773A3 (no)
MX (1) MXPA03010985A (no)
NO (1) NO20035324L (no)
NZ (1) NZ529848A (no)
PE (1) PE20030231A1 (no)
PL (1) PL366906A1 (no)
RU (1) RU2003138078A (no)
SK (1) SK14672003A3 (no)
SV (1) SV2003001061A (no)
UA (1) UA75149C2 (no)
UY (1) UY27312A1 (no)
WO (1) WO2002098879A1 (no)
ZA (1) ZA200309111B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2388111A (en) * 2002-05-01 2003-11-05 Bayer Ag Novel imidazotriazinone compounds
GB2388594A (en) * 2002-05-16 2003-11-19 Bayer Ag Imidazo-triazine PDE 4 inhibitors
FR2850653A1 (fr) * 2003-02-04 2004-08-06 Univ Pasteur Derives de pyrazolotriazine, procede de preparation et utilisations
JP2006219374A (ja) 2003-06-13 2006-08-24 Daiichi Asubio Pharma Co Ltd Pde7阻害作用を有するイミダゾトリアジノン誘導体
TW200745106A (en) * 2005-10-03 2007-12-16 Astrazeneca Ab Chemical compounds
EP2685983B1 (en) * 2011-03-17 2016-05-18 Algiax Pharmaceuticals GmbH Novel use of imidazotriazinones
WO2013156231A1 (en) * 2012-04-16 2013-10-24 Algiax Pharmaceuticals Gmbh Use of imidazotriazinones in neuropathic pain
WO2015144598A1 (en) * 2014-03-28 2015-10-01 Algiax Pharmaceuticals Gmbh Treatment of cognitive disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791025A (fr) 1971-11-19 1973-05-07 Allen & Hanburys Ltd Composes heterocycliques
GB1457873A (en) 1973-01-04 1976-12-08 Allen & Hanburys Ltd Imidazotriazines
DK109578A (da) 1977-03-25 1978-09-26 Allen & Hanburys Ltd Fremgangsmaade til fremstilling af heterocycliske forbindelser
EP2295436A1 (de) * 1997-11-12 2011-03-16 Bayer Schering Pharma AG 2-Phenyl-substituierte Imidazotriazinone als Phosphodiesterase V Inhibitoren
DE19827640A1 (de) * 1998-06-20 1999-12-23 Bayer Ag 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone
CA2323008C (en) * 1999-10-11 2005-07-12 Pfizer Inc. Pharmaceutically active compounds

Also Published As

Publication number Publication date
NO20035324D0 (no) 2003-11-28
NO20035324L (no) 2003-11-28
MXPA03010985A (es) 2004-10-28
US20050065153A1 (en) 2005-03-24
GT200200099A (es) 2003-02-13
BR0210910A (pt) 2004-06-08
US20030139415A1 (en) 2003-07-24
CA2449095A1 (en) 2002-12-12
CO5540381A2 (es) 2005-07-29
GB0113344D0 (en) 2001-07-25
EE200300570A (et) 2004-04-15
CZ20033275A3 (en) 2004-03-17
UA75149C2 (en) 2006-03-15
JP2004536078A (ja) 2004-12-02
HUP0400773A3 (en) 2007-09-28
SK14672003A3 (sk) 2004-08-03
ZA200309111B (en) 2004-11-24
EP1399447A1 (en) 2004-03-24
BG108381A (bg) 2004-11-30
CN1512993A (zh) 2004-07-14
PL366906A1 (en) 2005-02-07
UY27312A1 (es) 2003-02-28
US7115602B2 (en) 2006-10-03
HUP0400773A2 (hu) 2004-07-28
KR20040023605A (ko) 2004-03-18
RU2003138078A (ru) 2005-05-27
ECSP034872A (es) 2004-01-28
PE20030231A1 (es) 2003-05-16
WO2002098879A1 (en) 2002-12-12
SV2003001061A (es) 2003-03-18
CZ295609B6 (cs) 2005-08-17
NZ529848A (en) 2006-02-24

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