HRP20030494A2 - Imidazole and benzimidazole caspase inhibitors and uses thereof - Google Patents

Imidazole and benzimidazole caspase inhibitors and uses thereof Download PDF

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Publication number
HRP20030494A2
HRP20030494A2 HR20030494A HRP20030494A HRP20030494A2 HR P20030494 A2 HRP20030494 A2 HR P20030494A2 HR 20030494 A HR20030494 A HR 20030494A HR P20030494 A HRP20030494 A HR P20030494A HR P20030494 A2 HRP20030494 A2 HR P20030494A2
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HR
Croatia
Prior art keywords
disease
diseases
hydrogen
amino
carbonyl
Prior art date
Application number
HR20030494A
Other languages
English (en)
Croatian (hr)
Inventor
Kay David
Golec Julian
Original Assignee
Vertex Pharmaceuticals Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharmaceuticals Incorporated filed Critical Vertex Pharmaceuticals Incorporated
Publication of HRP20030494A2 publication Critical patent/HRP20030494A2/hr

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    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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    • C—CHEMISTRY; METALLURGY
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    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
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HR20030494A 2000-11-21 2003-06-17 Imidazole and benzimidazole caspase inhibitors and uses thereof HRP20030494A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25225200P 2000-11-21 2000-11-21
PCT/US2001/047688 WO2002042278A2 (en) 2000-11-21 2001-11-19 Imidazole and benzimidazole caspase inhibitors and uses thereof

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HRP20030494A2 true HRP20030494A2 (en) 2005-06-30

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HR20030494A HRP20030494A2 (en) 2000-11-21 2003-06-17 Imidazole and benzimidazole caspase inhibitors and uses thereof

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US (1) US7205327B2 (hu)
EP (1) EP1341767B1 (hu)
JP (2) JP4349802B2 (hu)
KR (1) KR20040020042A (hu)
CN (1) CN1298707C (hu)
AP (1) AP2003002811A0 (hu)
AT (1) ATE359274T1 (hu)
AU (1) AU2002232541A1 (hu)
BG (1) BG107841A (hu)
BR (1) BR0115546A (hu)
CA (1) CA2429630A1 (hu)
CO (1) CO7250442A2 (hu)
CZ (1) CZ20031730A3 (hu)
DE (1) DE60127860T2 (hu)
EA (1) EA200300601A1 (hu)
ES (1) ES2283456T3 (hu)
HK (1) HK1058672A1 (hu)
HR (1) HRP20030494A2 (hu)
HU (1) HUP0301870A3 (hu)
IL (1) IL155937A0 (hu)
IS (1) IS6822A (hu)
MX (1) MXPA03004459A (hu)
NO (1) NO20032270L (hu)
NZ (1) NZ526420A (hu)
PL (1) PL362612A1 (hu)
SK (1) SK7792003A3 (hu)
WO (1) WO2002042278A2 (hu)
ZA (1) ZA200303895B (hu)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20011350A1 (es) 2000-05-19 2002-01-15 Vertex Pharma PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE)
US7410956B2 (en) * 2002-02-11 2008-08-12 Vertex Pharmaceuticals Incorporated Caspase inhibitor prodrugs
WO2003088917A2 (en) * 2002-04-19 2003-10-30 Vertex Pharmaceuticals Incorporated Regulation of tnf-alpha
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