HRP20021008A2 - Indole derivatives useful for the treatment of cns disorders - Google Patents

Indole derivatives useful for the treatment of cns disorders Download PDF

Info

Publication number
HRP20021008A2
HRP20021008A2 HR20021008A HRP20021008A HRP20021008A2 HR P20021008 A2 HRP20021008 A2 HR P20021008A2 HR 20021008 A HR20021008 A HR 20021008A HR P20021008 A HRP20021008 A HR P20021008A HR P20021008 A2 HRP20021008 A2 HR P20021008A2
Authority
HR
Croatia
Prior art keywords
dihydro
indole
piperidin
quinolin
fluoro
Prior art date
Application number
HR20021008A
Other languages
English (en)
Croatian (hr)
Inventor
Bang-Andersen Benny
Felding Jacob
Kehler Jan
Andersen Kim
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of HRP20021008A2 publication Critical patent/HRP20021008A2/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HR20021008A 2000-06-14 2001-06-13 Indole derivatives useful for the treatment of cns disorders HRP20021008A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200000919 2000-06-14
US21244500P 2000-06-16 2000-06-16
PCT/DK2001/000406 WO2001096328A1 (en) 2000-06-14 2001-06-13 Indole derivatives useful for the treatment of cns disorders

Publications (1)

Publication Number Publication Date
HRP20021008A2 true HRP20021008A2 (en) 2005-02-28

Family

ID=26068835

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20021008A HRP20021008A2 (en) 2000-06-14 2001-06-13 Indole derivatives useful for the treatment of cns disorders

Country Status (20)

Country Link
US (2) US6890916B2 (cs)
EP (1) EP1294710B1 (cs)
JP (1) JP2004503550A (cs)
KR (1) KR20030007967A (cs)
AR (1) AR028685A1 (cs)
AT (2) ATE374197T1 (cs)
AU (2) AU2001273881B8 (cs)
BG (1) BG107449A (cs)
CA (1) CA2411412C (cs)
CZ (1) CZ200335A3 (cs)
DE (2) DE60111379T2 (cs)
DK (1) DK1468996T3 (cs)
ES (2) ES2290587T3 (cs)
HR (1) HRP20021008A2 (cs)
HU (1) HUP0301735A2 (cs)
NO (1) NO323236B1 (cs)
NZ (1) NZ523076A (cs)
PT (2) PT1294710E (cs)
SG (1) SG148840A1 (cs)
WO (1) WO2001096328A1 (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165274B1 (es) * 1999-06-04 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
SI1294710T1 (en) * 2000-06-14 2005-10-31 H. Lundbeck A/S Indole derivatives useful for the treatment of cns disorders
ES2172436B1 (es) 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
WO2003102097A1 (en) * 2002-05-31 2003-12-11 H. Lundbeck A/S The hydrochloride of (s)-(+)-3-[1-[2-(1-acetyl-2,3-dihydro-1h-indol-3-yl)ethyl]-1,2,3,6-tetrahydropyridin-4-yl]-6-chloro-1h-indole
AU2003257407A1 (en) * 2002-08-29 2004-03-19 H. Lundbeck A/S S-(+)-3-{1-(2-(2,3-dihydro-1h-indol-3-yl)ethyl)-3,6-dihydro-2h-pyridin-4-yl}-6-chloro-1h-indole and acid addition salts thereof
GB0306604D0 (en) * 2003-03-21 2003-04-30 Curidium Ltd Second medical use
WO2004108671A1 (en) * 2003-06-06 2004-12-16 Suven Life Sciences Limited Substituted indoles with serotonin receptor affinity, process for their preparation and pharmaceutical compositions containing them
GB0708186D0 (en) * 2007-04-27 2007-06-06 Merck Sharp & Dohme Therapeutic compounds
SE531698C2 (sv) 2007-07-12 2009-07-07 Respiratorius Ab Nya bronkdilaterande a,b-omättade amider

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9202915D0 (en) * 1992-02-12 1992-03-25 Wellcome Found Chemical compounds
ZA9711376B (en) * 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives
WO1999010346A1 (en) * 1997-08-22 1999-03-04 Eli Lilly And Company Limited Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands
GB9718833D0 (en) * 1997-09-04 1997-11-12 Merck Sharp & Dohme Therapeutic agents
GB9810886D0 (en) * 1998-05-13 1998-07-22 Lilly Industries Ltd Pharmaceutical compounds
GB9825413D0 (en) * 1998-11-19 1999-01-13 Lilly Co Eli Pharmaceutical compounds
WO2000040581A1 (en) * 1999-01-07 2000-07-13 American Home Products Corporation 3,4-dihydro-2h-benzo[1,4]oxazine derivatives
JP2002544223A (ja) * 1999-05-12 2002-12-24 ソルベイ・フアーマシユーチカルズ・ベー・ブイ 精神病性障害の治療方法
CA2341542A1 (en) * 1999-06-24 2000-12-28 Toray Industries, Inc. .alpha.1b-adrenergic receptor antagonists
GB2362381A (en) * 2000-05-18 2001-11-21 Lilly Co Eli Pharmaceutically active indolyl-piperidines

Also Published As

Publication number Publication date
DE60130691T2 (de) 2008-07-17
ATE297391T1 (de) 2005-06-15
EP1294710B1 (en) 2005-06-08
NZ523076A (en) 2004-09-24
NO20026005D0 (no) 2002-12-13
US20050176729A1 (en) 2005-08-11
DE60111379T2 (de) 2006-03-16
BG107449A (bg) 2003-09-30
PT1294710E (pt) 2005-10-31
SG148840A1 (en) 2009-01-29
EP1294710A1 (en) 2003-03-26
ATE374197T1 (de) 2007-10-15
ES2290587T3 (es) 2008-02-16
AU2001273881B8 (en) 2006-02-09
NO20026005L (no) 2002-12-13
HUP0301735A2 (hu) 2003-08-28
DE60111379D1 (de) 2005-07-14
CZ200335A3 (cs) 2003-04-16
AU2001273881B2 (en) 2005-12-22
WO2001096328A1 (en) 2001-12-20
DE60130691D1 (de) 2007-11-08
KR20030007967A (ko) 2003-01-23
US20030191133A1 (en) 2003-10-09
AR028685A1 (es) 2003-05-21
CA2411412C (en) 2008-09-02
JP2004503550A (ja) 2004-02-05
DK1468996T3 (da) 2008-01-07
US6890916B2 (en) 2005-05-10
NO323236B1 (no) 2007-02-05
ES2243508T3 (es) 2005-12-01
PT1468996E (pt) 2007-11-28
CA2411412A1 (en) 2001-12-20
AU7388101A (en) 2001-12-24
US7276508B2 (en) 2007-10-02

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