HRP20020828A2 - Use of il-18 inhibitors in atherosclerosis - Google Patents
Use of il-18 inhibitors in atherosclerosis Download PDFInfo
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- HRP20020828A2 HRP20020828A2 HRP20020828A HRP20020828A2 HR P20020828 A2 HRP20020828 A2 HR P20020828A2 HR P20020828 A HRP20020828 A HR P20020828A HR P20020828 A2 HRP20020828 A2 HR P20020828A2
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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EP00109606 | 2000-05-05 | ||
PCT/EP2001/004843 WO2001085201A2 (en) | 2000-05-05 | 2001-04-30 | Use of il-18 inhibitors for the treatment and/or prevention of atherosclerosis |
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CN (2) | CN1250286C (et) |
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AU (2) | AU2001267390B2 (et) |
BG (1) | BG65881B1 (et) |
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CA (1) | CA2407895C (et) |
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HR (1) | HRP20020828A2 (et) |
HU (1) | HU229375B1 (et) |
IL (2) | IL152567A0 (et) |
ME (1) | ME00554B (et) |
MX (1) | MXPA02010895A (et) |
NO (1) | NO329821B1 (et) |
PL (1) | PL209371B1 (et) |
PT (1) | PT1278540E (et) |
RS (1) | RS50926B (et) |
SI (1) | SI1278540T1 (et) |
SK (1) | SK287761B6 (et) |
UA (2) | UA78492C2 (et) |
WO (1) | WO2001085201A2 (et) |
ZA (1) | ZA200208228B (et) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
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KR101111103B1 (ko) * | 2000-02-10 | 2012-02-13 | 아보트 러보러터리즈 | 사람 인터류킨-18에 결합하는 항체 및 이를 제조하고 사용하는 방법 |
ME00549B (me) * | 2001-01-29 | 2011-10-10 | Serono Lab | Upotreba inhibitora il-18 za liječenje i/ili prevenciju srčanih oboljenja |
HU230294B1 (hu) * | 2001-05-25 | 2015-12-28 | Ares Trading S.A. | IL-18-inhibitorok alkalmazása központi idegrendszeri sérülések kezelésére vagy megelőzésére |
US6797727B2 (en) | 2001-07-16 | 2004-09-28 | Transition Therapeutics Inc. | Use of rhein or diacerhein compounds for the treatment or prevention of vascular diseases |
GB0210212D0 (en) * | 2002-05-03 | 2002-06-12 | Univ Southampton | Effects of dietary N-3 and N-6 pufa intake on atheromatous plaque stability |
US8729124B2 (en) | 2002-03-05 | 2014-05-20 | Pronova Biopharma Norge As | Use of EPA and DHA in secondary prevention |
DE60324777D1 (de) * | 2002-03-22 | 2009-01-02 | Inst Nat Sante Rech Med | Verwendung von il-18-inhibitoren zur behandlung und/oder prävention von peripheren gefässkrankheiten |
SI1601776T1 (sl) * | 2003-03-11 | 2008-10-31 | Serono Lab | Ekspresijski vektorji, ki vsebujejo mcmv ie2 promotor |
CA2524403C (en) | 2003-05-13 | 2013-07-09 | Applied Research Systems Ars Holding N.V. | Active variants of the il-18 binding protein and medical uses thereof |
US7968684B2 (en) | 2003-11-12 | 2011-06-28 | Abbott Laboratories | IL-18 binding proteins |
US20080044404A1 (en) * | 2004-04-15 | 2008-02-21 | Anna Cederholm | Annexin V for Preventing Atherothrombosis and Plaque Rupture |
CN101219208B (zh) * | 2005-01-04 | 2010-08-11 | 健能隆医药技术(上海)有限公司 | 白介素-22的医药用途 |
US7691611B2 (en) | 2005-06-03 | 2010-04-06 | Ares Trading S.A. | Production of recombinant IL-18 binding protein |
JP5091127B2 (ja) | 2005-06-10 | 2012-12-05 | アレス トレーディング ソシエテ アノニム | Il−18結合タンパク質の精製のための方法 |
WO2012025536A1 (en) | 2010-08-25 | 2012-03-01 | F. Hoffmann-La Roche Ag | Antibodies against il-18r1 and uses thereof |
JOP20200308A1 (ar) | 2012-09-07 | 2017-06-16 | Novartis Ag | جزيئات إرتباط il-18 |
MD707Z (ro) * | 2013-01-18 | 2014-07-31 | Институт Зоологии Академии Наук Молдовы | Metodă de identificare a secvenţelor polimorfe 4a/4b ale genei sintetazei endoteliale a oxidului nitric |
EP3978526A1 (en) | 2013-09-05 | 2022-04-06 | AB2 Bio SA | Il-18 binding protein (il-18bp) in inflammatory diseases |
US10882905B2 (en) | 2015-03-05 | 2021-01-05 | Ab2 Bio Sa | IL-18 binding protein (IL-18BP) and antibodies in inflammatory diseases |
CN110273591B (zh) | 2019-08-13 | 2023-12-12 | 上海杉脉电子科技发展有限公司 | 一种单动力微型智能锁 |
TW202233675A (zh) | 2020-10-29 | 2022-09-01 | 瑞士商諾華公司 | Il-18拮抗劑用於治療和/或預防異位性皮炎或相關病症之用途 |
CN112972655A (zh) * | 2021-04-16 | 2021-06-18 | 武汉大学 | 白细胞介素12在制备预防、缓解和/或治疗主动脉瘤药物中的应用 |
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US5985863A (en) * | 1996-09-12 | 1999-11-16 | Vertex Pharmaceuticals, Inc. | Compositions and methods for decreasing IGIF and IFN-γ production by administering an ICE inhibitor |
US5877197A (en) * | 1996-12-16 | 1999-03-02 | Karanewsky; Donald S. | C-terminal modified (N-substituted)-2-indolyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases |
IL121860A0 (en) * | 1997-08-14 | 1998-02-22 | Yeda Res & Dev | Interleukin-18 binding proteins their preparation and use |
CA2276216A1 (en) * | 1998-06-24 | 1999-12-24 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | An artificial peptide capable of neutralizing the biological activity of interleukin-18 |
EP0987552A3 (en) * | 1998-08-31 | 2000-06-07 | Pfizer Products Inc. | Diarylsulfonylurea binding proteins |
EP1110969A4 (en) * | 1998-09-01 | 2002-01-09 | Hayashibara Biochem Lab | INTERLEUKIN 18 BINDING PROTEIN |
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