HRP20020471B1 - Process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidine-3-(n,n-dimethyl-acetamide) and intermediates - Google Patents

Process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidine-3-(n,n-dimethyl-acetamide) and intermediates

Info

Publication number
HRP20020471B1
HRP20020471B1 HR20020471A HRP20020471A HRP20020471B1 HR P20020471 B1 HRP20020471 B1 HR P20020471B1 HR 20020471 A HR20020471 A HR 20020471A HR P20020471 A HRP20020471 A HR P20020471A HR P20020471 B1 HRP20020471 B1 HR P20020471B1
Authority
HR
Croatia
Prior art keywords
methyl
phenyl
dimethyl
imidazo
acetamide
Prior art date
Application number
HR20020471A
Other languages
English (en)
Croatian (hr)
Inventor
Pong� L�szl�
Reiter J�zsef
Simig Gyula
T�mpe P�ter
Hoffmann� Fekete Val�ria
R�v� Endre
Koncz L�szl�
Vereczkeyn� Don�th Gy�rgyi
Nagy K�lm�n
Original Assignee
Egis Gy�gyszergy�r RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU9904379A external-priority patent/HU227358B1/hu
Priority claimed from HU9904377A external-priority patent/HUP9904377A2/hu
Application filed by Egis Gy�gyszergy�r RT filed Critical Egis Gy�gyszergy�r RT
Publication of HRP20020471A2 publication Critical patent/HRP20020471A2/hr
Publication of HRP20020471B1 publication Critical patent/HRP20020471B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HR20020471A 1999-11-22 2000-11-22 Process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidine-3-(n,n-dimethyl-acetamide) and intermediates HRP20020471B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU9904379A HU227358B1 (en) 1999-11-22 1999-11-22 Novel process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidyne-3-(n,n-dimethyl-acetamide)
HU9904377A HUP9904377A2 (en) 1999-11-22 1999-11-22 6-methyl-2-(4-methyl-phenyl)-imidazole-[1,2-a]pyrimidine-3-acetic acid-esters and process for their preparation
PCT/HU2000/000120 WO2001038327A2 (en) 1999-11-22 2000-11-22 Process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidine-3-(n,n-dimethyl-acetamide) and intermediates

Publications (2)

Publication Number Publication Date
HRP20020471A2 HRP20020471A2 (en) 2005-10-31
HRP20020471B1 true HRP20020471B1 (en) 2007-12-31

Family

ID=90000034

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20020471A HRP20020471B1 (en) 1999-11-22 2000-11-22 Process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidine-3-(n,n-dimethyl-acetamide) and intermediates

Country Status (15)

Country Link
EP (1) EP1259509B1 (cs)
JP (1) JP2003518016A (cs)
KR (1) KR100656636B1 (cs)
CN (1) CN1227252C (cs)
AT (1) ATE304540T1 (cs)
AU (1) AU1873901A (cs)
CZ (1) CZ300711B6 (cs)
DE (1) DE60022684T2 (cs)
DK (1) DK1259509T3 (cs)
ES (1) ES2248154T3 (cs)
HR (1) HRP20020471B1 (cs)
PL (1) PL354366A1 (cs)
RU (1) RU2254334C2 (cs)
SK (1) SK7122002A3 (cs)
WO (1) WO2001038327A2 (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100398539C (zh) 2002-12-18 2008-07-02 马林克罗特公司 杂芳基乙酰胺的合成
WO2004087703A1 (en) * 2003-03-12 2004-10-14 Sun Pharmaceutical Industries Limited Process for the preparation of n,n,6-trimethyl-2-(4-methylphenyl)-imidazo[1,2-a]pyridine-3-acetamide
ES2483968T5 (es) 2005-05-26 2017-06-28 Alfa Laval Corporate Ab Método de latonado de artículos de acero inoxidable
CA2624340A1 (en) * 2005-10-03 2007-04-12 Mallinckrodt Inc. Process for preparing zolpidem hemitartrate and tartrate polymorphs
KR101008674B1 (ko) * 2008-01-25 2011-01-18 주식회사 이화창 컨테이너 및 그 컨테이너를 구비한 두피 마사지기
CN103360387B (zh) * 2012-03-28 2016-12-14 江苏豪森药业集团有限公司 一种制备化合物唑吡坦的方法
CN114105974A (zh) * 2020-08-27 2022-03-01 鲁南制药集团股份有限公司 一种唑吡坦的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2151834B1 (es) * 1998-08-06 2001-08-16 Sint Quimica Sa Procedimiento para preparar n,n,6-trimetil-2-(4-metilfenil)-imidazo-(1,2-a)-piridina-3-acetamida y sus sales.
NL1014634C1 (nl) * 1999-03-25 2000-08-03 Synthon Bv Zolpidemzouten.

Also Published As

Publication number Publication date
RU2254334C2 (ru) 2005-06-20
KR100656636B1 (ko) 2006-12-11
DE60022684D1 (de) 2005-10-20
ES2248154T3 (es) 2006-03-16
DE60022684T2 (de) 2006-06-29
CZ20021713A3 (cs) 2002-08-14
ATE304540T1 (de) 2005-09-15
EP1259509B1 (en) 2005-09-14
WO2001038327A2 (en) 2001-05-31
WO2001038327A3 (en) 2002-09-12
DK1259509T3 (da) 2006-01-16
JP2003518016A (ja) 2003-06-03
SK7122002A3 (en) 2002-10-08
EP1259509A1 (en) 2002-11-27
KR20020052213A (ko) 2002-07-02
PL354366A1 (en) 2004-01-12
CN1413212A (zh) 2003-04-23
HRP20020471A2 (en) 2005-10-31
AU1873901A (en) 2001-06-04
CN1227252C (zh) 2005-11-16
CZ300711B6 (cs) 2009-07-22

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Payment date: 20081017

Year of fee payment: 9

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Effective date: 20091123