HN2002000308A - Procedimiento para la produccción de sertralina sustancialmente pura en forma optica. - Google Patents
Procedimiento para la produccción de sertralina sustancialmente pura en forma optica.Info
- Publication number
- HN2002000308A HN2002000308A HN2002000308A HN2002000308A HN2002000308A HN 2002000308 A HN2002000308 A HN 2002000308A HN 2002000308 A HN2002000308 A HN 2002000308A HN 2002000308 A HN2002000308 A HN 2002000308A HN 2002000308 A HN2002000308 A HN 2002000308A
- Authority
- HN
- Honduras
- Prior art keywords
- procedure
- production
- substantially pure
- optical form
- pure sertraline
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000003287 optical effect Effects 0.000 title abstract 2
- VGKDLMBJGBXTGI-SJCJKPOMSA-N sertraline Chemical compound C1([C@@H]2CC[C@@H](C3=CC=CC=C32)NC)=CC=C(Cl)C(Cl)=C1 VGKDLMBJGBXTGI-SJCJKPOMSA-N 0.000 title abstract 2
- 229960002073 sertraline Drugs 0.000 title abstract 2
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
- 238000013375 chromatographic separation Methods 0.000 abstract 1
- 239000004927 clay Substances 0.000 abstract 1
- VJYFKVYYMZPMAB-UHFFFAOYSA-N ethoprophos Chemical compound CCCSP(=O)(OCC)SCCC VJYFKVYYMZPMAB-UHFFFAOYSA-N 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000007791 liquid phase Substances 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical class [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
- C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
EL PRESENTE INVENTO SE REFIERE A UN PROCEDIMIENTO PARA LA PRODUCCIÓN DE SERTRALINA SUSTANCIALMENTE PURA EN FORMA OPTICA, UTILIZA UNA SEPARACION CROMATOGRAFICA SOBRE UNA BASE QUIRAL SOLIDA Y ESTACIONARIA DE PARTICULAS ESFERICAS DE ARCILLA CON UNA INTERCALA QUE CONTIENE UN COMPLEJO METALICO- ORGANICO OPTICAMENTE PURO Y UNA BASE LIQUIDA MOVIL QUE PREFERENTEMENTE CONTIENE AL MENOS METIL - ACETANO. LA FASE LIQUIDA ESTA PREFERENTEMENTE LIBRE DEACETONITRILO. EL PROCEDIMIENTO PUEDE OPERAR A TEMPERATURAS SUPERIORES A 40°C.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33542901P | 2001-10-31 | 2001-10-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HN2002000308A true HN2002000308A (es) | 2003-01-18 |
Family
ID=23311732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HN2002000308A HN2002000308A (es) | 2001-10-31 | 2002-10-24 | Procedimiento para la produccción de sertralina sustancialmente pura en forma optica. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6683220B2 (es) |
| EP (1) | EP1444188A1 (es) |
| JP (1) | JP2005507935A (es) |
| KR (1) | KR20040070345A (es) |
| CN (1) | CN1578756A (es) |
| AR (1) | AR037046A1 (es) |
| BR (1) | BR0213787A (es) |
| CA (1) | CA2464916A1 (es) |
| EG (1) | EG23132A (es) |
| HN (1) | HN2002000308A (es) |
| IL (1) | IL161256A0 (es) |
| MX (1) | MXPA04003289A (es) |
| MY (1) | MY133291A (es) |
| PA (1) | PA8557601A1 (es) |
| PL (1) | PL369722A1 (es) |
| RS (1) | RS37204A (es) |
| RU (1) | RU2004116325A (es) |
| SV (1) | SV2003001293A (es) |
| TN (1) | TNSN02087A1 (es) |
| TW (1) | TWI221468B (es) |
| WO (1) | WO2003037840A1 (es) |
| ZA (1) | ZA200402652B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2242555T1 (es) * | 2003-04-14 | 2005-11-16 | Teva Pharmaceutical Industries Limited | Hidrogenacion de intermediarios de imina de sertralina con catalizadores. |
| US20060128955A1 (en) * | 2003-05-09 | 2006-06-15 | Vela Pharmaceuticals, Inc. | Method of isolating (R)-tofisopam |
| KR100739537B1 (ko) | 2004-01-07 | 2007-07-13 | 주식회사 카이로라이트 | 카이랄 무기-유기 혼성 다공성 물질 및 이의 제조 방법 |
| US7345201B2 (en) | 2005-02-23 | 2008-03-18 | Teva Pharmaceutical Industries, Ltd. | Processes for preparing sertraline |
| US7413660B2 (en) * | 2005-09-30 | 2008-08-19 | 3M Innovative Properties Company | Single pass method and apparatus for separating a target molecule from a liquid mixture |
| KR100925316B1 (ko) * | 2007-12-20 | 2009-11-04 | 노운섭 | 접합필름인쇄용 잉크조성물 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0527234B1 (en) * | 1991-02-28 | 2003-06-04 | Daicel Chemical Industries, Ltd. | Separating agent |
| US5403898A (en) * | 1992-05-04 | 1995-04-04 | Brigham Young University | Single arm attached cyclodextrin polysiloxanes and use thereof as chiral stationary phases in chromatographic separation of enantiomers |
| ES2108484T3 (es) * | 1993-11-30 | 1997-12-16 | Pfizer | Procedimiento para la preparacion de una tetralona asimetrica. |
| WO1999057089A1 (en) * | 1998-05-01 | 1999-11-11 | Pfizer Products Inc. | Process for the production of enantiomerically pure or optically enriched sertraline-tetralone using continuous chromatography |
| FR2785196B1 (fr) * | 1998-10-29 | 2000-12-15 | Inst Francais Du Petrole | Procede et dispositif de separation avec des zones chromatographiques a longueur variable |
-
2002
- 2002-09-18 US US10/246,796 patent/US6683220B2/en not_active Expired - Fee Related
- 2002-09-27 WO PCT/US2002/030567 patent/WO2003037840A1/en not_active Application Discontinuation
- 2002-09-27 CA CA002464916A patent/CA2464916A1/en not_active Abandoned
- 2002-09-27 IL IL16125602A patent/IL161256A0/xx unknown
- 2002-09-27 RS YU37204A patent/RS37204A/sr unknown
- 2002-09-27 PL PL02369722A patent/PL369722A1/xx not_active Application Discontinuation
- 2002-09-27 BR BR0213787-9A patent/BR0213787A/pt not_active IP Right Cessation
- 2002-09-27 MX MXPA04003289A patent/MXPA04003289A/es unknown
- 2002-09-27 EP EP02775999A patent/EP1444188A1/en not_active Withdrawn
- 2002-09-27 JP JP2003540123A patent/JP2005507935A/ja active Pending
- 2002-09-27 RU RU2004116325/04A patent/RU2004116325A/ru not_active Application Discontinuation
- 2002-09-27 CN CNA028216113A patent/CN1578756A/zh active Pending
- 2002-09-27 KR KR10-2004-7006379A patent/KR20040070345A/ko not_active Application Discontinuation
- 2002-10-01 TW TW091122801A patent/TWI221468B/zh not_active IP Right Cessation
- 2002-10-08 MY MYPI20023750A patent/MY133291A/en unknown
- 2002-10-09 EG EG2002101104A patent/EG23132A/xx active
- 2002-10-15 SV SV2002001293A patent/SV2003001293A/es not_active Application Discontinuation
- 2002-10-24 HN HN2002000308A patent/HN2002000308A/es unknown
- 2002-10-28 AR ARP020104076A patent/AR037046A1/es active IP Right Grant
- 2002-10-30 TN TNTNSN02087A patent/TNSN02087A1/fr unknown
- 2002-10-31 PA PA20028557601A patent/PA8557601A1/es unknown
-
2004
- 2004-04-05 ZA ZA200402652A patent/ZA200402652B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EG23132A (en) | 2004-04-28 |
| AR037046A1 (es) | 2004-10-20 |
| MY133291A (en) | 2007-11-30 |
| JP2005507935A (ja) | 2005-03-24 |
| CA2464916A1 (en) | 2003-05-08 |
| BR0213787A (pt) | 2004-11-09 |
| PA8557601A1 (es) | 2004-02-07 |
| US6683220B2 (en) | 2004-01-27 |
| US20030105364A1 (en) | 2003-06-05 |
| ZA200402652B (en) | 2006-05-31 |
| CN1578756A (zh) | 2005-02-09 |
| EP1444188A1 (en) | 2004-08-11 |
| WO2003037840A8 (en) | 2004-07-22 |
| IL161256A0 (en) | 2004-09-27 |
| TWI221468B (en) | 2004-10-01 |
| MXPA04003289A (es) | 2004-07-23 |
| KR20040070345A (ko) | 2004-08-07 |
| RU2004116325A (ru) | 2005-11-10 |
| PL369722A1 (en) | 2005-05-02 |
| TNSN02087A1 (fr) | 2004-03-05 |
| RS37204A (en) | 2006-12-15 |
| SV2003001293A (es) | 2003-04-03 |
| WO2003037840A1 (en) | 2003-05-08 |
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