RS37204A - Proces for preparation odoptically pure or enriched racematic tetralone - Google Patents
Proces for preparation odoptically pure or enriched racematic tetraloneInfo
- Publication number
- RS37204A RS37204A YU37204A YUP37204A RS37204A RS 37204 A RS37204 A RS 37204A YU 37204 A YU37204 A YU 37204A YU P37204 A YUP37204 A YU P37204A RS 37204 A RS37204 A RS 37204A
- Authority
- RS
- Serbia
- Prior art keywords
- racematic
- odoptically
- tetralone
- proces
- enriched
- Prior art date
Links
- XHLHPRDBBAGVEG-UHFFFAOYSA-N 1-tetralone Chemical compound C1=CC=C2C(=O)CCCC2=C1 XHLHPRDBBAGVEG-UHFFFAOYSA-N 0.000 title 1
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 abstract 1
- KXKVLQRXCPHEJC-UHFFFAOYSA-N acetic acid trimethyl ester Natural products COC(C)=O KXKVLQRXCPHEJC-UHFFFAOYSA-N 0.000 abstract 1
- 238000013375 chromatographic separation Methods 0.000 abstract 1
- 239000004927 clay Substances 0.000 abstract 1
- 239000011229 interlayer Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- VGKDLMBJGBXTGI-SJCJKPOMSA-N sertraline Chemical compound C1([C@@H]2CC[C@@H](C3=CC=CC=C32)NC)=CC=C(Cl)C(Cl)=C1 VGKDLMBJGBXTGI-SJCJKPOMSA-N 0.000 abstract 1
- 229960002073 sertraline Drugs 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
- C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Postupak za dobijanje u velikoj meri optički čistog sertralina upotrebom hromatografskog razdvajanja na čvrstoj stacionarnoj kiralnoj fazi sfernih glinenih čestica koje imaju jedan međusloj koji sadrži jedan optički čist metal-organski kompleks, i tečne mobilne faze koje preporučljivo sadrži najmanje metil acetat. Preporučuje se da tečna mobilna faza bude oslobođena acetonitrila. Postupak se može izvesti na temperaturi od 40°C.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33542901P | 2001-10-31 | 2001-10-31 | |
PCT/US2002/030567 WO2003037840A1 (en) | 2001-10-31 | 2002-09-27 | Process for the preparation of optically pure or enriched racemic tetralone |
Publications (1)
Publication Number | Publication Date |
---|---|
RS37204A true RS37204A (en) | 2006-12-15 |
Family
ID=23311732
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU37204A RS37204A (en) | 2001-10-31 | 2002-09-27 | Proces for preparation odoptically pure or enriched racematic tetralone |
Country Status (22)
Country | Link |
---|---|
US (1) | US6683220B2 (sr) |
EP (1) | EP1444188A1 (sr) |
JP (1) | JP2005507935A (sr) |
KR (1) | KR20040070345A (sr) |
CN (1) | CN1578756A (sr) |
AR (1) | AR037046A1 (sr) |
BR (1) | BR0213787A (sr) |
CA (1) | CA2464916A1 (sr) |
EG (1) | EG23132A (sr) |
HN (1) | HN2002000308A (sr) |
IL (1) | IL161256A0 (sr) |
MX (1) | MXPA04003289A (sr) |
MY (1) | MY133291A (sr) |
PA (1) | PA8557601A1 (sr) |
PL (1) | PL369722A1 (sr) |
RS (1) | RS37204A (sr) |
RU (1) | RU2004116325A (sr) |
SV (1) | SV2003001293A (sr) |
TN (1) | TNSN02087A1 (sr) |
TW (1) | TWI221468B (sr) |
WO (1) | WO2003037840A1 (sr) |
ZA (1) | ZA200402652B (sr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200503991A (en) * | 2003-04-14 | 2005-02-01 | Teva Pharma | Hydrogenation of imine intermediates of sertraline with catalysts |
US20060128955A1 (en) * | 2003-05-09 | 2006-06-15 | Vela Pharmaceuticals, Inc. | Method of isolating (R)-tofisopam |
KR100739537B1 (ko) | 2004-01-07 | 2007-07-13 | 주식회사 카이로라이트 | 카이랄 무기-유기 혼성 다공성 물질 및 이의 제조 방법 |
US7345201B2 (en) * | 2005-02-23 | 2008-03-18 | Teva Pharmaceutical Industries, Ltd. | Processes for preparing sertraline |
US7413660B2 (en) * | 2005-09-30 | 2008-08-19 | 3M Innovative Properties Company | Single pass method and apparatus for separating a target molecule from a liquid mixture |
KR100925316B1 (ko) * | 2007-12-20 | 2009-11-04 | 노운섭 | 접합필름인쇄용 잉크조성물 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992015617A1 (en) * | 1991-02-28 | 1992-09-17 | Daicel Chemical Industries, Ltd. | Separating agent |
US5403898A (en) * | 1992-05-04 | 1995-04-04 | Brigham Young University | Single arm attached cyclodextrin polysiloxanes and use thereof as chiral stationary phases in chromatographic separation of enantiomers |
DK0724552T3 (da) * | 1993-11-30 | 1997-12-22 | Pfizer | Fremgangsmåde til fremstilling af chiralt tetralon |
DK1073618T3 (da) * | 1998-05-01 | 2004-03-15 | Pfizer Prod Inc | Fremgangsmåde til fremstilling af enantiomerisk ren eller optisk beriget sertralin-tetralon under anvendelse af kontinuerlig kromatografi |
FR2785196B1 (fr) * | 1998-10-29 | 2000-12-15 | Inst Francais Du Petrole | Procede et dispositif de separation avec des zones chromatographiques a longueur variable |
-
2002
- 2002-09-18 US US10/246,796 patent/US6683220B2/en not_active Expired - Fee Related
- 2002-09-27 EP EP02775999A patent/EP1444188A1/en not_active Withdrawn
- 2002-09-27 CA CA002464916A patent/CA2464916A1/en not_active Abandoned
- 2002-09-27 CN CNA028216113A patent/CN1578756A/zh active Pending
- 2002-09-27 JP JP2003540123A patent/JP2005507935A/ja active Pending
- 2002-09-27 RS YU37204A patent/RS37204A/sr unknown
- 2002-09-27 KR KR10-2004-7006379A patent/KR20040070345A/ko not_active Application Discontinuation
- 2002-09-27 IL IL16125602A patent/IL161256A0/xx unknown
- 2002-09-27 BR BR0213787-9A patent/BR0213787A/pt not_active IP Right Cessation
- 2002-09-27 WO PCT/US2002/030567 patent/WO2003037840A1/en not_active Application Discontinuation
- 2002-09-27 PL PL02369722A patent/PL369722A1/xx not_active Application Discontinuation
- 2002-09-27 MX MXPA04003289A patent/MXPA04003289A/es unknown
- 2002-09-27 RU RU2004116325/04A patent/RU2004116325A/ru not_active Application Discontinuation
- 2002-10-01 TW TW091122801A patent/TWI221468B/zh not_active IP Right Cessation
- 2002-10-08 MY MYPI20023750A patent/MY133291A/en unknown
- 2002-10-09 EG EG2002101104A patent/EG23132A/xx active
- 2002-10-15 SV SV2002001293A patent/SV2003001293A/es not_active Application Discontinuation
- 2002-10-24 HN HN2002000308A patent/HN2002000308A/es unknown
- 2002-10-28 AR ARP020104076A patent/AR037046A1/es active IP Right Grant
- 2002-10-30 TN TNTNSN02087A patent/TNSN02087A1/fr unknown
- 2002-10-31 PA PA20028557601A patent/PA8557601A1/es unknown
-
2004
- 2004-04-05 ZA ZA200402652A patent/ZA200402652B/en unknown
Also Published As
Publication number | Publication date |
---|---|
PA8557601A1 (es) | 2004-02-07 |
IL161256A0 (en) | 2004-09-27 |
KR20040070345A (ko) | 2004-08-07 |
PL369722A1 (en) | 2005-05-02 |
ZA200402652B (en) | 2006-05-31 |
TWI221468B (en) | 2004-10-01 |
EP1444188A1 (en) | 2004-08-11 |
MY133291A (en) | 2007-11-30 |
US6683220B2 (en) | 2004-01-27 |
SV2003001293A (es) | 2003-04-03 |
RU2004116325A (ru) | 2005-11-10 |
JP2005507935A (ja) | 2005-03-24 |
WO2003037840A1 (en) | 2003-05-08 |
US20030105364A1 (en) | 2003-06-05 |
EG23132A (en) | 2004-04-28 |
WO2003037840A8 (en) | 2004-07-22 |
MXPA04003289A (es) | 2004-07-23 |
AR037046A1 (es) | 2004-10-20 |
CA2464916A1 (en) | 2003-05-08 |
HN2002000308A (es) | 2003-01-18 |
TNSN02087A1 (fr) | 2004-03-05 |
BR0213787A (pt) | 2004-11-09 |
CN1578756A (zh) | 2005-02-09 |
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