BR0213787A - Processo para a preparação de tetralona racêmica oticamente pura ou enriquecida - Google Patents

Processo para a preparação de tetralona racêmica oticamente pura ou enriquecida

Info

Publication number
BR0213787A
BR0213787A BR0213787-9A BR0213787A BR0213787A BR 0213787 A BR0213787 A BR 0213787A BR 0213787 A BR0213787 A BR 0213787A BR 0213787 A BR0213787 A BR 0213787A
Authority
BR
Brazil
Prior art keywords
optically pure
preparation
racemic tetralone
enriched racemic
phase
Prior art date
Application number
BR0213787-9A
Other languages
English (en)
Inventor
Laurent Berger
Raphael Duval
Philippe Taillasson
Ingo Weber
Alexander Wick
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR0213787A publication Critical patent/BR0213787A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

"PROCESSO PARA A PREPARAçãO DE TETRALONA RACêMICA OTICAMENTE PURA OU ENRIQUECIDA". A presente invenção refere-se a um processo para produzir sertralina substancialmente oticamente pura que utiliza separação cromatográfica sobre uma fase quiral estacionária sólida de partículas de argila esféricas tendo uma intercamada contendo um complexo metálico-orgânico oticamente puro, e uma fase móvel líquida de preferência contendo pelo menos acetato de metila. A fase móvel líquida é de preferência livre de acetonitrila. O processo é operável a temperaturas acima de 40<198>C.
BR0213787-9A 2001-10-31 2002-09-27 Processo para a preparação de tetralona racêmica oticamente pura ou enriquecida BR0213787A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33542901P 2001-10-31 2001-10-31
PCT/US2002/030567 WO2003037840A1 (en) 2001-10-31 2002-09-27 Process for the preparation of optically pure or enriched racemic tetralone

Publications (1)

Publication Number Publication Date
BR0213787A true BR0213787A (pt) 2004-11-09

Family

ID=23311732

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0213787-9A BR0213787A (pt) 2001-10-31 2002-09-27 Processo para a preparação de tetralona racêmica oticamente pura ou enriquecida

Country Status (22)

Country Link
US (1) US6683220B2 (pt)
EP (1) EP1444188A1 (pt)
JP (1) JP2005507935A (pt)
KR (1) KR20040070345A (pt)
CN (1) CN1578756A (pt)
AR (1) AR037046A1 (pt)
BR (1) BR0213787A (pt)
CA (1) CA2464916A1 (pt)
EG (1) EG23132A (pt)
HN (1) HN2002000308A (pt)
IL (1) IL161256A0 (pt)
MX (1) MXPA04003289A (pt)
MY (1) MY133291A (pt)
PA (1) PA8557601A1 (pt)
PL (1) PL369722A1 (pt)
RS (1) RS37204A (pt)
RU (1) RU2004116325A (pt)
SV (1) SV2003001293A (pt)
TN (1) TNSN02087A1 (pt)
TW (1) TWI221468B (pt)
WO (1) WO2003037840A1 (pt)
ZA (1) ZA200402652B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200503991A (en) * 2003-04-14 2005-02-01 Teva Pharma Hydrogenation of imine intermediates of sertraline with catalysts
US20060128955A1 (en) * 2003-05-09 2006-06-15 Vela Pharmaceuticals, Inc. Method of isolating (R)-tofisopam
KR100739537B1 (ko) 2004-01-07 2007-07-13 주식회사 카이로라이트 카이랄 무기-유기 혼성 다공성 물질 및 이의 제조 방법
US7345201B2 (en) * 2005-02-23 2008-03-18 Teva Pharmaceutical Industries, Ltd. Processes for preparing sertraline
US7413660B2 (en) * 2005-09-30 2008-08-19 3M Innovative Properties Company Single pass method and apparatus for separating a target molecule from a liquid mixture
KR100925316B1 (ko) * 2007-12-20 2009-11-04 노운섭 접합필름인쇄용 잉크조성물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992015617A1 (en) * 1991-02-28 1992-09-17 Daicel Chemical Industries, Ltd. Separating agent
US5403898A (en) * 1992-05-04 1995-04-04 Brigham Young University Single arm attached cyclodextrin polysiloxanes and use thereof as chiral stationary phases in chromatographic separation of enantiomers
DK0724552T3 (da) * 1993-11-30 1997-12-22 Pfizer Fremgangsmåde til fremstilling af chiralt tetralon
DK1073618T3 (da) * 1998-05-01 2004-03-15 Pfizer Prod Inc Fremgangsmåde til fremstilling af enantiomerisk ren eller optisk beriget sertralin-tetralon under anvendelse af kontinuerlig kromatografi
FR2785196B1 (fr) * 1998-10-29 2000-12-15 Inst Francais Du Petrole Procede et dispositif de separation avec des zones chromatographiques a longueur variable

Also Published As

Publication number Publication date
PA8557601A1 (es) 2004-02-07
IL161256A0 (en) 2004-09-27
KR20040070345A (ko) 2004-08-07
PL369722A1 (en) 2005-05-02
ZA200402652B (en) 2006-05-31
TWI221468B (en) 2004-10-01
EP1444188A1 (en) 2004-08-11
MY133291A (en) 2007-11-30
US6683220B2 (en) 2004-01-27
SV2003001293A (es) 2003-04-03
RU2004116325A (ru) 2005-11-10
JP2005507935A (ja) 2005-03-24
WO2003037840A1 (en) 2003-05-08
US20030105364A1 (en) 2003-06-05
EG23132A (en) 2004-04-28
WO2003037840A8 (en) 2004-07-22
MXPA04003289A (es) 2004-07-23
AR037046A1 (es) 2004-10-20
RS37204A (en) 2006-12-15
CA2464916A1 (en) 2003-05-08
HN2002000308A (es) 2003-01-18
TNSN02087A1 (fr) 2004-03-05
CN1578756A (zh) 2005-02-09

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A,7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2064 DE 27/07/2010.