HK61979A - Novel 1-aryl-2-(1-imidazolyl)alkyl ethers and thioethers and their use as antifungal agents - Google Patents

Novel 1-aryl-2-(1-imidazolyl)alkyl ethers and thioethers and their use as antifungal agents

Info

Publication number
HK61979A
HK61979A HK619/79A HK61979A HK61979A HK 61979 A HK61979 A HK 61979A HK 619/79 A HK619/79 A HK 619/79A HK 61979 A HK61979 A HK 61979A HK 61979 A HK61979 A HK 61979A
Authority
HK
Hong Kong
Prior art keywords
thioethers
imidazolyl
aryl
novel
alkyl ethers
Prior art date
Application number
HK619/79A
Other languages
English (en)
Inventor
G E Gymer
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of HK61979A publication Critical patent/HK61979A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK619/79A 1975-04-30 1979-08-30 Novel 1-aryl-2-(1-imidazolyl)alkyl ethers and thioethers and their use as antifungal agents HK61979A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1792275A GB1475271A (en) 1975-04-30 1975-04-30 1-aryl-2-1-imidazolyl-alkyl ethers and thioethers and their use as antifungal agents

Publications (1)

Publication Number Publication Date
HK61979A true HK61979A (en) 1979-09-07

Family

ID=10103597

Family Applications (1)

Application Number Title Priority Date Filing Date
HK619/79A HK61979A (en) 1975-04-30 1979-08-30 Novel 1-aryl-2-(1-imidazolyl)alkyl ethers and thioethers and their use as antifungal agents

Country Status (35)

Country Link
US (1) US4062966A (da)
JP (1) JPS51133266A (da)
AR (1) AR212592A1 (da)
AT (1) AT350551B (da)
BE (1) BE841309A (da)
BG (1) BG25517A3 (da)
CA (1) CA1063123A (da)
CH (1) CH605930A5 (da)
CS (1) CS191302B2 (da)
DD (1) DD124983A5 (da)
DE (1) DE2619381C3 (da)
DK (1) DK147682C (da)
EG (1) EG12222A (da)
ES (1) ES447525A1 (da)
FI (1) FI64157C (da)
FR (1) FR2309223A1 (da)
GB (1) GB1475271A (da)
GR (1) GR60383B (da)
HK (1) HK61979A (da)
HU (1) HU174210B (da)
IE (1) IE43272B1 (da)
IL (1) IL49406A (da)
LU (1) LU74866A1 (da)
MX (1) MX3240E (da)
MY (1) MY8000109A (da)
NL (1) NL162911C (da)
NO (1) NO143970C (da)
PH (1) PH12906A (da)
PL (1) PL104365B1 (da)
PT (1) PT65045B (da)
RO (1) RO72609A (da)
SE (1) SE418860B (da)
SU (1) SU622405A3 (da)
YU (1) YU40646B (da)
ZA (1) ZA762036B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1511390A (en) * 1975-12-04 1978-05-17 Pfizer Ltd Imidazolylalkyl sulphide antifungal agents
DE2860862D1 (en) * 1977-10-13 1981-10-29 Siegfried Ag Imidazolylethylene-oxyalkyloxy derivatives and their thio analogues, methods for their preparation and pharmaceutical compositions containing them
IT1096361B (it) * 1978-05-18 1985-08-26 Recordati Chem Pharm Dibenzileteri sostituiti terapeuticamente attivi
US4272545A (en) * 1979-02-02 1981-06-09 Syntex (U.S.A.) Inc. Derivatives of thienyl- and furyl-substituted N-butyl and N-phenyl imidazoles
US4307105A (en) * 1979-07-05 1981-12-22 E. R. Squibb & Sons, Inc. Imidazolylethoxymethyl derivatives of thiazole
US4315023A (en) * 1979-09-06 1982-02-09 Westwood Pharmaceuticals, Inc. 1-Phenethylimidazole derivatives
US4248881A (en) * 1979-12-20 1981-02-03 E. R. Squibb & Sons, Inc. Imidazolylethoxymethyl derivatives of pyrazole
CA1155853A (en) * 1980-06-06 1983-10-25 Joseph A. Martin Imidazole derivatives and preparation thereof
US4458079A (en) * 1980-08-08 1984-07-03 Bristol-Myers Company Sulfur-containing imidazoles
ES8504779A1 (es) * 1984-02-02 1985-05-01 Ferrer Int Procedimiento de obtencion de nuevos derivados de 1h-imidazol
US4766140A (en) * 1984-06-18 1988-08-23 Eli Lilly And Company Method of inhibiting aromatase
IT1200422B (it) * 1985-03-19 1989-01-18 Ripari Gero Ist Farm Biolog Composto con attivita' antimicrobia,sua preparazione e composizioni farmaceutiche che lo contengono
DE3932552A1 (de) * 1989-09-29 1991-04-11 Basf Ag Verfahren zur herstellung von 1-hydroxyimidazol
US5270032A (en) * 1990-10-04 1993-12-14 The Research Foundation Of State University Of New York Composition and method for the prevention and treatment of candidiasis
US5399552A (en) * 1991-10-17 1995-03-21 Merck & Co, Inc Antibiotic peptides bearing aminoalkylthioether moieties
US6545163B1 (en) * 1995-10-02 2003-04-08 Napp Technologies Process to prepare 1-aryl-2-(1-imidazolyl) alkyl ethers and thioethers
CN101519403B (zh) * 2009-04-08 2012-05-30 广东工业大学 一种合成噻康唑的方法
BRPI0904249B1 (pt) 2009-08-28 2018-03-06 Biolab Sanus Farmacêutica Ltda. Compostos éteres aralquil benzílicos, processo de preparação dos mesmos, uso dos referidos compostos, composição farmacêutica
US11185548B2 (en) 2016-12-23 2021-11-30 Helmholtz Zentrum Munchen—Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) Inhibitors of cytochrome P450 family 7 subfamily B member 1 (CYP7B1) for use in treating diseases
CN110537545A (zh) * 2019-09-12 2019-12-06 青岛农业大学 噻康唑在制备用于防治植物病原菌的杀菌剂中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3354173A (en) * 1964-04-16 1967-11-21 Janssen Pharmaceutica Nv Imidazole carboxylates
SU557755A3 (ru) * 1968-08-19 1977-05-05 Янссен Фармасьютика Н.В. (Фирма) Способ получени производных имидазола
US3575999A (en) * 1968-08-19 1971-04-20 Janssen Pharmaceutica Nv Ketal derivatives of imidazole
CH531516A (de) * 1969-05-21 1972-12-15 Bayer Ag Verfahren zur Herstellung neuer Phenylimidazolyl-fettsäure-derivate
US3658813A (en) * 1970-01-13 1972-04-25 Janssen Pharmaceutica Nv 1-(beta-aryl-beta-(r-oxy)-ethyl)-imidazoles
DE2059949C3 (de) * 1970-12-05 1979-12-13 Bayer Ag, 5090 Leverkusen Thienyl-fettsäurederivate, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2359922A1 (de) * 1973-12-01 1975-06-05 Hoechst Ag (1-alkyl-5-nitro-imidazolyl-2-alkyl)- heteroaryl-verbindungen und verfahren zu ihrer herstellung
DE2362171A1 (de) * 1973-12-14 1975-06-26 Hoechst Ag (1-alkyl-5-nitro-imidazolyl-2-alkyl)heteroaryl-verbindungen und verfahren zu ihrer herstellung
US3991202A (en) * 1974-01-31 1976-11-09 Janssen Pharmaceutica N.V. Imidazolium salts

Also Published As

Publication number Publication date
NO143970B (no) 1981-02-09
BE841309A (fr) 1976-10-29
IE43272B1 (en) 1981-01-28
FR2309223B1 (da) 1978-08-25
DE2619381B2 (de) 1977-10-06
NL162911C (nl) 1980-07-15
DK154776A (da) 1976-10-31
GR60383B (en) 1978-05-24
RO72609A (ro) 1982-02-01
PT65045B (en) 1977-09-13
DD124983A5 (da) 1977-03-23
PT65045A (en) 1976-05-01
NO761481L (da) 1976-11-02
YU100976A (en) 1982-06-30
DK147682C (da) 1985-07-15
SE418860B (sv) 1981-06-29
IL49406A0 (en) 1976-06-30
BG25517A3 (en) 1978-10-10
EG12222A (en) 1978-09-30
ATA310276A (de) 1978-11-15
AU1319976A (en) 1977-03-31
NL7604583A (nl) 1976-11-02
IE43272L (en) 1976-10-30
CS191302B2 (en) 1979-06-29
PL104365B1 (pl) 1979-08-31
DK147682B (da) 1984-11-12
MX3240E (es) 1980-08-06
IL49406A (en) 1979-09-30
NO143970C (no) 1981-05-20
FR2309223A1 (fr) 1976-11-26
NL162911B (nl) 1980-02-15
CH605930A5 (da) 1978-10-13
DE2619381C3 (de) 1980-10-16
HU174210B (hu) 1979-11-28
DE2619381A1 (de) 1976-11-11
FI64157B (fi) 1983-06-30
JPS5331872B2 (da) 1978-09-05
PH12906A (en) 1979-10-04
FI64157C (fi) 1983-10-10
SU622405A3 (ru) 1978-08-30
CA1063123A (en) 1979-09-25
LU74866A1 (da) 1977-12-02
JPS51133266A (en) 1976-11-18
SE7604975L (sv) 1976-10-31
FI761200A (da) 1976-10-31
MY8000109A (en) 1980-12-31
GB1475271A (en) 1977-06-01
ZA762036B (en) 1977-04-27
ES447525A1 (es) 1977-07-01
US4062966A (en) 1977-12-13
YU40646B (en) 1986-04-30
AR212592A1 (es) 1978-08-15
AT350551B (de) 1979-06-11

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