HK42791A - Carboxylic acid esters of steroids - Google Patents

Carboxylic acid esters of steroids

Info

Publication number
HK42791A
HK42791A HK427/91A HK42791A HK42791A HK 42791 A HK42791 A HK 42791A HK 427/91 A HK427/91 A HK 427/91A HK 42791 A HK42791 A HK 42791A HK 42791 A HK42791 A HK 42791A
Authority
HK
Hong Kong
Prior art keywords
steroids
carboxylic acid
acid esters
beta
distinguished
Prior art date
Application number
HK427/91A
Other languages
English (en)
Inventor
Julius Dr Schmidlin
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of HK42791A publication Critical patent/HK42791A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • C07J71/0015Oxiranes at position 9(11)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J3/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Fats And Perfumes (AREA)
HK427/91A 1983-08-18 1991-05-30 Carboxylic acid esters of steroids HK42791A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH451283 1983-08-18

Publications (1)

Publication Number Publication Date
HK42791A true HK42791A (en) 1991-06-07

Family

ID=4277476

Family Applications (1)

Application Number Title Priority Date Filing Date
HK427/91A HK42791A (en) 1983-08-18 1991-05-30 Carboxylic acid esters of steroids

Country Status (21)

Country Link
US (1) US4607028A (es)
EP (1) EP0135476B1 (es)
JP (1) JPS6058999A (es)
KR (1) KR850001725A (es)
AT (1) ATE37186T1 (es)
AU (1) AU3204484A (es)
CA (1) CA1234564A (es)
CY (1) CY1593A (es)
DD (1) DD227966A5 (es)
DE (1) DE3474025D1 (es)
DK (1) DK160993C (es)
ES (1) ES8601234A1 (es)
FI (1) FI80888C (es)
GR (1) GR80131B (es)
HK (1) HK42791A (es)
HU (1) HUT34991A (es)
IL (1) IL72702A0 (es)
NO (1) NO160212C (es)
PT (1) PT79106B (es)
SG (1) SG32091G (es)
ZA (1) ZA846406B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL78144A0 (en) * 1985-04-04 1986-07-31 Draco Ab Novel androstane-17beta-carboxylic acid esters
WO1990015816A1 (en) * 1989-06-16 1990-12-27 The Upjohn Company Suramin type compounds and angiostatic steroids to inhibit angiogenesis
FR2701262B1 (fr) * 1993-02-05 1995-03-24 Roussel Uclaf Nouveau procédé de préparation de stéroïdes 6 alpa, 9 alpha-difluorés et nouveaus intermédiaires.
JPH07119308A (ja) * 1993-10-27 1995-05-09 Koa:Kk 移動作業床による外壁貼りの吊り支え工法並にその装置
GB9501286D0 (en) * 1995-01-24 1995-03-15 Ciba Geigy Ag Pharmaceutical compositions and preparations thereof
US5981517A (en) * 1996-05-09 1999-11-09 Soft Drugs, Inc. Androstene derivatives
AUPP583198A0 (en) * 1998-09-11 1998-10-01 Soltec Research Pty Ltd Mousse composition
GB0015876D0 (en) * 2000-06-28 2000-08-23 Novartis Ag Organic compounds
CO5310534A1 (es) * 2000-08-05 2003-08-29 Glaxo Group Ltd Nuevos derivados de androstano anti-inflamatorios
US6787532B2 (en) * 2000-08-05 2004-09-07 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivatives
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6858593B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
GB0019172D0 (en) * 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6777400B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6750210B2 (en) * 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
GB0029562D0 (en) * 2000-12-04 2001-01-17 Novartis Ag Organic compounds
UA77656C2 (en) * 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
ES2314052T3 (es) * 2001-04-30 2009-03-16 Glaxo Group Limited Derivados de ester de 17beta-carbotioato de androstano con un grupo ester ciclico en la posicion 17alfa.
GB0202216D0 (en) * 2002-01-31 2002-03-20 Glaxo Group Ltd Novel compounds
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1384372A (en) * 1971-01-20 1975-02-19 Glaxo Lab Ltd Dereivatives of 17alpha-hydroxyandrost-4-ene-17beta-carboxylic acids
GB1514476A (en) * 1974-08-30 1978-06-14 Glaxo Lab Ltd Alkyl and haloalkyl androst-4-ene and androsta-1,4-diene-17beta-carboxylates
JPS5297597A (en) * 1976-02-09 1977-08-16 Walt Disney Prod Guide device of ship
JPS5938239B2 (ja) * 1976-02-12 1984-09-14 グラクソ・ラボラトリ−ス・リミテツド 新規ステロイド化合物
CH628355A5 (de) * 1976-02-24 1982-02-26 Ciba Geigy Ag Verfahren zur herstellung neuer androstadien-17beta-carbonsaeuren und ihrer ester und salze.
CH634081A5 (en) * 1977-04-13 1983-01-14 Ciba Geigy Ag Process for the preparation of novel androstadiene-17beta-carboxylic acid esters
ZA814440B (en) * 1980-07-10 1982-10-27 Otsuka Pharma Co Ltd Soft steroids having anti-inflammatory activity

Also Published As

Publication number Publication date
DE3474025D1 (en) 1988-10-20
JPS6058999A (ja) 1985-04-05
IL72702A0 (en) 1984-11-30
AU3204484A (en) 1985-02-21
FI843219A0 (fi) 1984-08-15
ATE37186T1 (de) 1988-09-15
EP0135476A2 (de) 1985-03-27
JPH0253440B2 (es) 1990-11-16
DK160993B (da) 1991-05-13
NO160212C (no) 1989-03-22
SG32091G (en) 1991-06-21
NO843298L (no) 1985-02-19
FI80888B (fi) 1990-04-30
EP0135476A3 (en) 1985-12-18
NO160212B (no) 1988-12-12
CY1593A (en) 1992-04-03
KR850001725A (ko) 1985-04-01
ES535242A0 (es) 1985-11-01
EP0135476B1 (de) 1988-09-14
ES8601234A1 (es) 1985-11-01
PT79106A (en) 1984-09-01
DK396284D0 (da) 1984-08-17
GR80131B (en) 1984-12-19
DK396284A (da) 1985-02-19
ZA846406B (en) 1985-03-27
CA1234564A (en) 1988-03-29
DD227966A5 (de) 1985-10-02
PT79106B (en) 1986-11-14
DK160993C (da) 1991-11-04
FI80888C (fi) 1990-08-10
US4607028A (en) 1986-08-19
HUT34991A (en) 1985-05-28
FI843219A (fi) 1985-02-19

Similar Documents

Publication Publication Date Title
DE3474025D1 (en) Carboxylic acid esters of steroids
GB1384372A (en) Dereivatives of 17alpha-hydroxyandrost-4-ene-17beta-carboxylic acids
JPS5278848A (en) Preparation of novel propionic acid ester derivatives
JPS57122100A (en) 4-pregnene derivative and manufacture
ZA947739B (en) Corticoid-17, 21-dicarboxylic esters and corticosteroid 17-carboxylic ester 21-carbonic esters processes for their preparation and pharmaceuticals containing these compounds
DE3063603D1 (en) Process for the separation of ursodeoxycholic acid from chenodeoxycholic acid and products obtained during the process
GB2017087A (en) Process for the preparation of xanthone derivatives
IL64902A0 (en) Carbacyclin derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
JPS523046A (en) Prepration of 4-homotwistane-3-carboxylic acid esters
JPS5265263A (en) Azetidinone compounds
JPS51127068A (en) A process for preparing 8-azaprostanoic acid derivatives.
GB1475075A (en) Derivatives of glycyrrhetinic and oleanolic acids
JPS5283568A (en) Piperidine derivatives
JPS51131857A (en) Process for preparation of substituted cyclopropanecarboxylic acid est ers
JPS54148770A (en) Steroid derivative
JPS51131821A (en) Process for preparation of gamma-halo-delta-unsaturated carboxylic acids
JPS5283368A (en) Synthesis of 2-pyprolidone derivatives
JPS54117457A (en) Diacylsteroid derivative
JPS51131818A (en) Process for preparation of r-unsaturated carboxylic acid esters
JPS52100467A (en) 8-azaprostanic acid derivatives
JPS5788200A (en) Synthetic intermediate of corticoids
JPS52105120A (en) N-acyl-alpha-acetoxyamino acid esters and their preparation
JPS5283866A (en) Cephem or penam compounds
JPS52118441A (en) 2-carbamoyl-3-methyl-3-(4-isobutylphenyl)glycidic acid derivatives an d method of preparing the same

Legal Events

Date Code Title Description
PE Patent expired

Effective date: 20040812

PE Patent expired