HK37391A - Antidepressant 1,2,4-triazolone compounds - Google Patents

Antidepressant 1,2,4-triazolone compounds Download PDF

Info

Publication number
HK37391A
HK37391A HK373/91A HK37391A HK37391A HK 37391 A HK37391 A HK 37391A HK 373/91 A HK373/91 A HK 373/91A HK 37391 A HK37391 A HK 37391A HK 37391 A HK37391 A HK 37391A
Authority
HK
Hong Kong
Prior art keywords
antidepressant
triazolone compounds
compounds
triazolone
phenoxyalkyl
Prior art date
Application number
HK373/91A
Other languages
English (en)
Inventor
E. Gammans Richard
W. Smith David
P. Yevich Joseph
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24145128&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK37391(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of HK37391A publication Critical patent/HK37391A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK373/91A 1983-09-30 1991-05-16 Antidepressant 1,2,4-triazolone compounds HK37391A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/538,027 US4613600A (en) 1983-09-30 1983-09-30 Antidepressant 1,2,4-triazolone compounds

Publications (1)

Publication Number Publication Date
HK37391A true HK37391A (en) 1991-05-24

Family

ID=24145128

Family Applications (1)

Application Number Title Priority Date Filing Date
HK373/91A HK37391A (en) 1983-09-30 1991-05-16 Antidepressant 1,2,4-triazolone compounds

Country Status (25)

Country Link
US (1) US4613600A (cs)
JP (1) JPS60100560A (cs)
KR (1) KR880002624B1 (cs)
AT (1) AT387963B (cs)
AU (1) AU561460B2 (cs)
BE (1) BE900714A (cs)
CA (1) CA1237723A (cs)
CH (1) CH661924A5 (cs)
CY (1) CY1541A (cs)
DE (1) DE3435745C2 (cs)
DK (1) DK169546B1 (cs)
ES (1) ES8601966A1 (cs)
FI (1) FI83310C (cs)
FR (1) FR2552759B1 (cs)
GB (1) GB2147297B (cs)
GR (1) GR80475B (cs)
HK (1) HK37391A (cs)
IE (1) IE58084B1 (cs)
IT (1) IT1178522B (cs)
LU (1) LU85561A1 (cs)
MY (1) MY102123A (cs)
NL (1) NL8402946A (cs)
SE (1) SE465928B (cs)
YU (1) YU45667B (cs)
ZA (1) ZA847589B (cs)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4487773A (en) * 1981-03-16 1984-12-11 Mead Johnson & Company 1,2,4-Triazol-3-one antidepressants
YU44721B (en) * 1983-11-30 1990-12-31 Bristol Myers Co Process for obtaining 4-(2-phenoxyethyl)-1,2,4-triazolone
CA1331757C (en) * 1988-02-29 1994-08-30 Janssen Pharmaceutica Naamloze Vennootschap 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols
US5504086A (en) * 1989-10-17 1996-04-02 Ellinwood, Jr.; Everett H. Intraoral dosing method of administering trifluorobenzodiazepines, propoxyphene, and nefazodone
US5256664A (en) * 1992-04-28 1993-10-26 Bristol-Myers Squibb Company Antidepressant 3-halophenylpiperazinylpropyl derivatives of substituted triazolones and triazoldiones
DE4425144A1 (de) * 1994-07-15 1996-01-18 Basf Ag Triazolverbindungen und deren Verwendung
US6403593B1 (en) 1995-07-14 2002-06-11 Abbott Laboratories Triazole compounds and the use thereof
DE19728996A1 (de) 1997-07-07 1999-01-14 Basf Ag Triazolverbindungen und deren Verwendung
US6586437B2 (en) 1999-04-09 2003-07-01 Sepracor Inc. (S)-hydroxynefazodone antipsychotic therapy
CA2369732A1 (en) 1999-04-09 2000-10-19 Sepracor Inc. R-hydroxynefazodone
US6469008B2 (en) 1999-04-09 2002-10-22 Sepracor Inc. (R)-hydroxynefazodone antipsychotic therapy
US6465469B1 (en) 1999-04-09 2002-10-15 Sepracor Inc. S-hydroxynefazodone
ATE445838T1 (de) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
WO2005102366A2 (en) * 2004-04-19 2005-11-03 Philip Maxwell Satow Lithium combinations, and uses related thereto
CA2789097C (en) 2005-04-28 2017-02-21 Proteus Digital Health, Inc. Pharma-informatics system
CA2663377A1 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
WO2009111031A2 (en) * 2008-03-04 2009-09-11 Intra-Cellular Therapies, Inc. Methods of treating vasomotor symptoms
PL2398500T3 (pl) 2009-02-20 2019-09-30 2-Bbb Medicines B.V. System dostarczania leków na bazie glutationu
BRPI1011188B1 (pt) 2009-05-06 2019-10-15 Laboratory Skin Care, Inc. Composições de liberação dérmica compreendendo complexos de partículas de agente ativo-fosfato de cálcio e métodos para usar as mesmas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
WO2012072665A1 (en) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors
EP2753179A4 (en) 2011-09-09 2015-03-04 Univ Leland Stanford Junior TOPICAL ITRACONAZOLE FORMULATIONS AND THEIR USE

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione
IT1052119B (it) * 1972-10-16 1981-06-20 Sigma Tau Ind Farmaceuti Derivati del triazolinone e procedimento per la loro preparazione
US4338317A (en) * 1981-03-16 1982-07-06 Mead Johnson & Company Phenoxyethyl-1,2,4,-triazol-3-one antidepressants

Also Published As

Publication number Publication date
DE3435745A1 (de) 1985-04-11
KR850002270A (ko) 1985-05-10
LU85561A1 (fr) 1985-06-04
GB2147297A (en) 1985-05-09
BE900714A (fr) 1985-03-28
DK169546B1 (da) 1994-11-28
ATA310884A (de) 1988-09-15
FI83310C (fi) 1991-06-25
MY102123A (en) 1992-03-31
FR2552759B1 (fr) 1988-10-07
SE465928B (sv) 1991-11-18
SE8404869L (sv) 1985-03-31
JPH0542435B2 (cs) 1993-06-28
ES536286A0 (es) 1985-11-16
FI83310B (fi) 1991-03-15
YU172184A (en) 1986-10-31
GB8424535D0 (en) 1984-11-07
SE8404869D0 (sv) 1984-09-28
KR880002624B1 (ko) 1988-12-07
IE842476L (en) 1985-03-30
IE58084B1 (en) 1993-06-30
ES8601966A1 (es) 1985-11-16
CH661924A5 (de) 1987-08-31
GR80475B (en) 1985-01-31
ZA847589B (en) 1985-05-29
US4613600A (en) 1986-09-23
CY1541A (en) 1991-03-22
DK468284A (da) 1985-03-31
FR2552759A1 (fr) 1985-04-05
AT387963B (de) 1989-04-10
YU45667B (sh) 1992-07-20
GB2147297B (en) 1987-04-15
AU3364884A (en) 1985-04-04
FI843779L (fi) 1985-03-31
CA1237723A (en) 1988-06-07
NL8402946A (nl) 1985-04-16
IT8422922A0 (it) 1984-09-28
FI843779A0 (fi) 1984-09-26
DK468284D0 (da) 1984-09-28
JPS60100560A (ja) 1985-06-04
DE3435745C2 (de) 1994-11-03
AU561460B2 (en) 1987-05-07
IT1178522B (it) 1987-09-09

Similar Documents

Publication Publication Date Title
HK37391A (en) Antidepressant 1,2,4-triazolone compounds
TR199802691T1 (xx) Pestisid etkili 3-(ikameli fenil)-5-(tienil ya da furil)-1,2,4-triazoller
DK89595A (da) Fremgangsmåde til fremstilling af 1-(3-dimethylaminopropyl)-1'-(4-fluorphenyl)-1,3-dihydroisobenzofuran-5-carbonnitril
TR200001603T2 (tr) Yeni bileşikler
AT382373B (de) Verfahren zur herstellung von neuen 2-(4-(4,4dialkyl-2,6-piperidin-dion-1-yl)-butyl)-1piperazinyl)-pyrimidinen
RU93052411A (ru) (-)-энантиомер-{([4-(1,4,5,6-тетрагидро-4-метил-6-оксо-3-пиридазинил)фенил])-гидразоно} пропандинитрил
ATE236153T1 (de) 4-trifluormethyl-3-oxazolylpyridine, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als schädlingsbekämpfungsmittel
ATE116297T1 (de) Heterocyclische acetonitrile und ihre verwendung als fungizide.
AR227542A1 (es) Procedimiento para preparar derivados de 4-(4-amino-6,7-dimetoxi-quinazolin-2-il)-1-(2,4-dioxo-2,2,3,4-tetrahidro-pirimidin-6-il)-piperazina
KR960016716A (ko) 테트라졸리논
EP0995430A3 (de) Verwendung von Wirkstoffen, gewählt aus der Gruppe der 1,2-Diacylglycerole, zur Stärkung der Barrierefunktion der Haut
IT8421471A0 (it) Dro-1h-1,4-diazepina ad attivita'derivato di 1-[bis-(4-fluorofenil)calcio antagonista, sua preparaziometil]-4-(3-fenil-2-propenil)-esaine e composizioni che lo contengono
KR940005592A (ko) 살균제(2- 아릴- 2- 치환)에틸-1, 2, 4- 트리아졸들
DK1123291T3 (da) Fremgangsmåde til fremstilling af 3-(substitueret phenyl)-5-thienyl (eller furyl)-1,2,4-triazoler og hidtil ukendte mellemprodukter anvendt derved
ES2001809A6 (es) Un procedimiento para la preparacion de nuevas 3-(4,-fenil-piperazinil)alquil-quinazolin-2,4-(1h,3h)-dionas sustituidas
ATE307578T1 (de) Neue verwendung von (r)-(-)-2-(5-(4-fluorophenyl)-3-pyridylmethylam nomethyl)-chromane und ihrer physiologisch verträglichen salze
DK0591236T3 (da) Fremgangsmåde til fremstilling af 5-(3-butyryl-2,4,6-trimethyl)-2-(1-(ethoxyimino)propyl)-3-hydroxycyklohex-2-en-1-on
ATE207481T1 (de) Kristallformen von 1-(5-methansulfonamidoindolyl- 2-carbonyl)-4-(3-(1-methylethylamino)-2- pyridinyl) piperazin
IT8023422A0 (it) 5-(4-piridinil)-2 (1h)-piridinoni, utili come agenti cardiotonici, eloro preparazione.
ZA816489B (en) Pharmacologically active 4-(2-hydroxy-4-(substituted)phenyl)-naphthalen-2(1h)-ones and 2-ols,derivatives thereof and intermediates therefor
ATE35410T1 (de) Herstellung von 1-(3,4-dimethoxyphenylethylamino)-3-(substituie te phenoxy)-2-propanolen.
EP0232205A3 (en) Diene derivatives and vasodilators containing the same
ATE28865T1 (de) Benzoylharnstoff-verbindungen als schaedlingsbekaempfungsmittel.
DE69940922D1 (de) Polymorphe Form B von 3-(Cyclopropylmethoxy)-4-i4-(methylsulfonyl)phenyl -5,5-dimethyl-5H-furan-2-on
EP0174584A3 (de) Salicylamid-Derivate

Legal Events

Date Code Title Description
PE Patent expired

Effective date: 20040927

PE Patent expired