HK32793A - Substantially anhydrous crystalline cefadroxil and method for producing it - Google Patents
Substantially anhydrous crystalline cefadroxil and method for producing itInfo
- Publication number
- HK32793A HK32793A HK327/93A HK32793A HK32793A HK 32793 A HK32793 A HK 32793A HK 327/93 A HK327/93 A HK 327/93A HK 32793 A HK32793 A HK 32793A HK 32793 A HK32793 A HK 32793A
- Authority
- HK
- Hong Kong
- Prior art keywords
- cefadroxil
- water
- substantially anhydrous
- solvate
- added
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/12—Separation; Purification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878714180A GB8714180D0 (en) | 1987-06-17 | 1987-06-17 | Anhydrous crystalline cefadroxil |
| US07/825,737 US5329001A (en) | 1987-06-17 | 1992-01-27 | Substantially anhydrous crystalline cefadroxil and method for producing it |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK32793A true HK32793A (en) | 1993-04-08 |
Family
ID=26292369
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK327/93A HK32793A (en) | 1987-06-17 | 1993-04-01 | Substantially anhydrous crystalline cefadroxil and method for producing it |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5329001A (cs) |
| EP (1) | EP0295333B1 (cs) |
| JP (1) | JPS63316785A (cs) |
| KR (1) | KR950011744B1 (cs) |
| CN (1) | CN1022922C (cs) |
| AT (1) | ATE78257T1 (cs) |
| AU (1) | AU595410B2 (cs) |
| CA (1) | CA1339213C (cs) |
| DE (1) | DE3780454T2 (cs) |
| DK (1) | DK680487A (cs) |
| ES (1) | ES2051724T3 (cs) |
| FI (1) | FI87787C (cs) |
| GB (1) | GB8714180D0 (cs) |
| GR (1) | GR3005733T3 (cs) |
| HK (1) | HK32793A (cs) |
| NO (1) | NO168360C (cs) |
| PH (1) | PH24594A (cs) |
| PT (1) | PT86525B (cs) |
| SU (1) | SU1595340A3 (cs) |
| YU (1) | YU44650B (cs) |
| ZA (1) | ZA879700B (cs) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4898938A (en) * | 1987-08-03 | 1990-02-06 | Rifar S.R.L. | Method for preparing crystalline cefadroxil monohydrate |
| CA2466806A1 (en) | 2001-10-24 | 2003-05-01 | Sepracor Inc. | Method of resolving amlodipine racemate |
| US20040077849A1 (en) * | 2002-10-16 | 2004-04-22 | Orchid Chemicals & Pharmaceuticals Limited | Process for the preparation of cefadroxil |
| CN1311830C (zh) * | 2004-02-27 | 2007-04-25 | 石药集团中奇制药技术（石家庄）有限公司 | 头孢羟氨苄口腔崩解片及其制备方法 |
| KR101420451B1 (ko) | 2006-05-19 | 2014-07-16 | 디에스엠 시노켐 파마슈티칼스 네덜란드 비.브이. | 세파드록실의 결정화 방법 |
| CN102134250B (zh) * | 2011-01-19 | 2013-03-13 | 天津大学 | 一种头孢羟氨苄单水合物的结晶方法及结晶 |
| CN105534937B (zh) * | 2015-12-30 | 2019-12-03 | 石药集团欧意药业有限公司 | 一种头孢羟氨苄片剂及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2163514A1 (de) * | 1971-12-21 | 1973-07-05 | Toyama Chemical Co Ltd | Verfahren zur herstellung von cephalosporinen |
| BE793191A (fr) * | 1971-12-28 | 1973-06-22 | Toyama Chemical Co Ltd | Procede pour produire des acides 7-acylamido-3-cephem-4- carboxyliques |
| US3985741A (en) * | 1972-09-15 | 1976-10-12 | Bristol-Myers Company | Production of p-hydroxycephalexin |
| GB1532682A (en) * | 1976-04-27 | 1978-11-22 | Bristol Myers Co | Process for the preparation of cephadroxil |
| DE3313818A1 (de) * | 1983-04-16 | 1984-10-18 | Hoechst Ag, 6230 Frankfurt | Neue kristallmodifikation von ceftazidim |
| JPS60231683A (ja) * | 1984-05-02 | 1985-11-18 | Teijin Ltd | セフアロスポリン誘導体その製造法及びそれを有効成分とする抗菌剤 |
| US4904776A (en) * | 1987-04-24 | 1990-02-27 | Rifar S.R.L. | Method for producing crystalline cefadroxil hemihydrate |
-
1987
- 1987-06-17 GB GB878714180A patent/GB8714180D0/en active Pending
- 1987-11-23 DE DE8787117225T patent/DE3780454T2/de not_active Expired - Lifetime
- 1987-11-23 EP EP87117225A patent/EP0295333B1/en not_active Expired - Lifetime
- 1987-11-23 ES ES87117225T patent/ES2051724T3/es not_active Expired - Lifetime
- 1987-11-23 AT AT87117225T patent/ATE78257T1/de not_active IP Right Cessation
- 1987-12-22 DK DK680487A patent/DK680487A/da not_active Application Discontinuation
- 1987-12-24 AU AU83041/87A patent/AU595410B2/en not_active Ceased
- 1987-12-28 ZA ZA879700A patent/ZA879700B/xx unknown
- 1987-12-29 CA CA000555491A patent/CA1339213C/en not_active Expired - Fee Related
- 1987-12-29 YU YU2428/87A patent/YU44650B/xx unknown
-
1988
- 1988-01-05 NO NO880027A patent/NO168360C/no unknown
- 1988-01-11 KR KR1019880000124A patent/KR950011744B1/ko not_active Expired - Fee Related
- 1988-01-11 PT PT86525A patent/PT86525B/pt not_active IP Right Cessation
- 1988-01-25 SU SU884355130A patent/SU1595340A3/ru active
- 1988-02-04 JP JP63024867A patent/JPS63316785A/ja active Pending
- 1988-02-10 CN CN88100566A patent/CN1022922C/zh not_active Expired - Fee Related
- 1988-03-07 FI FI881039A patent/FI87787C/fi not_active IP Right Cessation
- 1988-04-04 PH PH36728A patent/PH24594A/en unknown
-
1992
- 1992-01-27 US US07/825,737 patent/US5329001A/en not_active Expired - Fee Related
- 1992-09-17 GR GR920402056T patent/GR3005733T3/el unknown
-
1993
- 1993-04-01 HK HK327/93A patent/HK32793A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU595410B2 (en) | 1990-03-29 |
| SU1595340A3 (ru) | 1990-09-23 |
| NO168360C (no) | 1992-02-12 |
| EP0295333A2 (en) | 1988-12-21 |
| JPS63316785A (ja) | 1988-12-26 |
| GB8714180D0 (en) | 1987-07-22 |
| DK680487D0 (da) | 1987-12-22 |
| CN1022922C (zh) | 1993-12-01 |
| FI881039L (fi) | 1988-12-18 |
| ES2051724T3 (es) | 1994-07-01 |
| PH24594A (en) | 1990-08-17 |
| YU44650B (en) | 1990-10-31 |
| KR950011744B1 (ko) | 1995-10-09 |
| FI87787C (fi) | 1993-02-25 |
| YU242887A (en) | 1988-12-31 |
| DE3780454D1 (de) | 1992-08-20 |
| EP0295333A3 (en) | 1989-10-18 |
| US5329001A (en) | 1994-07-12 |
| FI87787B (fi) | 1992-11-13 |
| DE3780454T2 (de) | 1992-12-17 |
| PT86525A (en) | 1989-05-31 |
| KR890000496A (ko) | 1989-03-15 |
| CA1339213C (en) | 1997-08-05 |
| DK680487A (da) | 1988-12-18 |
| CN88100566A (zh) | 1988-12-28 |
| EP0295333B1 (en) | 1992-07-15 |
| GR3005733T3 (cs) | 1993-06-07 |
| NO880027L (no) | 1988-12-19 |
| NO880027D0 (no) | 1988-01-05 |
| AU8304187A (en) | 1988-12-22 |
| ZA879700B (cs) | 1988-06-23 |
| ATE78257T1 (de) | 1992-08-15 |
| FI881039A0 (fi) | 1988-03-07 |
| PT86525B (pt) | 1992-07-31 |
| NO168360B (no) | 1991-11-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR840000866B1 (ko) | 세팔로스포린 용매화물의 제조방법 | |
| EP0302145B1 (en) | Method for preparing crystalline cefadroxil monohydrate | |
| US4694079A (en) | 3-propenyl cephalosporin solvates | |
| EP0295333B1 (en) | Substantially anhydrous crystalline cefadroxil and method for producing it | |
| EP0287751B1 (en) | Crystalline cefadroxil and method for producing it | |
| EP0113568B1 (en) | Intermediates for the preparation of ceftazidine, and process for their preparation | |
| CZ195097A3 (en) | Process for preparing cephotaxim and a sodium salt thereof | |
| US4962195A (en) | Solvate of cefadroxyl | |
| US4977257A (en) | DMF solvates of a β-lactam antibiotic | |
| US5023331A (en) | Cefadroxil solvates | |
| KR100308746B1 (ko) | 로라카베프이소프로판올레이트및로라카베프이소프로판올레이트를로라카베프일수화물로전환시키는방법 | |
| EP0308123B1 (en) | Crystalline antibiotic intermediate | |
| KR950011745B1 (ko) | 결정성 세파드록실 및 이의 제조방법 | |
| CA1339420C (en) | Cefadroxil solvates and method for producing the same | |
| KR960011778B1 (ko) | 신규한 결정성 세팔로스포린 유도체의 제조방법 | |
| JP2662414B2 (ja) | チアゾール誘導体 | |
| KR960000359B1 (ko) | 세포페라존 나트륨의 제조방법 | |
| KR960011777B1 (ko) | 신규한 결정성 세팔로스포린 유도체 및 그의 제조방법 | |
| KR830001970B1 (ko) | 세파로스포린 유도체의 제조방법 | |
| HU195225B (en) | Process for producing crystalline monohydrate of cefem compound | |
| JPS63115886A (ja) | 結晶性セフアロスポリン化合物 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |