HK32689A - 2-oxo-imidazolidine compounds,a process for preparing the same and a pharmaceutical composition - Google Patents
2-oxo-imidazolidine compounds,a process for preparing the same and a pharmaceutical compositionInfo
- Publication number
- HK32689A HK32689A HK326/89A HK32689A HK32689A HK 32689 A HK32689 A HK 32689A HK 326/89 A HK326/89 A HK 326/89A HK 32689 A HK32689 A HK 32689A HK 32689 A HK32689 A HK 32689A
- Authority
- HK
- Hong Kong
- Prior art keywords
- oxo
- preparing
- pharmaceutical composition
- same
- imidazolidine compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP57088637A JPS6058233B2 (ja) | 1982-05-24 | 1982-05-24 | 2−オキソイミダゾリジン誘導体及びその製法 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK32689A true HK32689A (en) | 1989-04-28 |
Family
ID=13948325
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK326/89A HK32689A (en) | 1982-05-24 | 1989-04-20 | 2-oxo-imidazolidine compounds,a process for preparing the same and a pharmaceutical composition |
Country Status (8)
Country | Link |
---|---|
US (1) | US4508727A (xx) |
EP (1) | EP0095163B1 (xx) |
JP (1) | JPS6058233B2 (xx) |
DE (2) | DE3373100D1 (xx) |
ES (2) | ES522678A0 (xx) |
HK (1) | HK32689A (xx) |
MY (1) | MY100095A (xx) |
SG (1) | SG5989G (xx) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61293538A (ja) * | 1985-06-24 | 1986-12-24 | Shinto Paint Co Ltd | 固体または半固体溶質の溶媒による溶解方法 |
KR930004646B1 (ko) * | 1986-12-09 | 1993-06-02 | 다나베 세이야꾸 가부시끼가이샤 | 심기능 부전의 예방 및 치료제 |
DE3782229T2 (de) * | 1986-12-12 | 1993-03-04 | Tanabe Seiyaku Co | Verwendung von 2-oxo-imidazolidin-derivaten zur behandlung von nierenkrankheiten. |
FR2620700B1 (fr) * | 1987-09-17 | 1990-06-01 | Adir | Procede de synthese d'alpha amino acides n alkyles et leurs esters. application a la synthese de carboxyalkyl dipeptides |
JPH066833Y2 (ja) * | 1988-05-17 | 1994-02-23 | 川澄化学工業株式会社 | 輸液バッグ |
JPH0645603B2 (ja) * | 1988-12-16 | 1994-06-15 | 田辺製薬株式会社 | 光学活性2‐オキソイミダゾリジン誘導体の製法 |
JPH07121916B2 (ja) * | 1993-12-10 | 1995-12-25 | 田辺製薬株式会社 | 光学活性3−アシル−2−オキソイミダゾリジン−4−カルボン酸誘導体及びその製法 |
CA2495962A1 (en) | 2002-08-19 | 2004-03-04 | Pfizer Products Inc. | Combination therapy for hyperproliferative diseases |
CL2004000366A1 (es) * | 2003-02-26 | 2005-01-07 | Pharmacia Corp Sa Organizada B | USO DE UNA COMBINACION DE UN COMPUESTO DERIVADO DE PIRAZOL INHIBIDOR DE QUINASA p38, Y UN INHIBIDOR DE ACE PARA TRATAR DISFUNCION RENAL, ENFERMEDAD CARDIOVASCULAR Y VASCULAR, RETINOPATIA, NEUROPATIA, EDEMA, DISFUNCION ENDOTELIAL O INSULINOPATIA. |
US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
JP4780437B2 (ja) * | 2004-12-08 | 2011-09-28 | 大原薬品工業株式会社 | 2−オキソイミダゾリジン誘導体の製造方法 |
JP4799085B2 (ja) * | 2005-09-02 | 2011-10-19 | 株式会社カネカ | 光学活性n置換アミノアシル環状尿素誘導体の製造法 |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
CN101663262B (zh) | 2006-12-01 | 2014-03-26 | 百时美施贵宝公司 | 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物 |
JP5206926B2 (ja) * | 2007-07-30 | 2013-06-12 | 株式会社Dnpファインケミカル宇都宮 | 塩酸イミダプリルの製造方法 |
BR112014004370A2 (pt) | 2011-08-26 | 2017-03-21 | Wockhardt Ltd | métodos para tratar distúrbios cardiovasculares |
KR101695582B1 (ko) | 2013-04-17 | 2017-01-13 | 화이자 인코포레이티드 | 심혈관 질환을 치료하기 위한 n-피페리딘-3-일벤즈아미드 유도체 |
CN104119424B (zh) * | 2014-07-01 | 2018-12-18 | 上海天慈生物谷生物工程有限公司 | (4s)-3-[(2s)-2[(1s)-1-乙氧羰基-3-苯丙基]氨基丙酰基]-1-甲基-2-氧代咪唑啉-4-羧酸的制备方法 |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
CN105713068B (zh) * | 2014-12-04 | 2021-04-20 | 湖南九典制药股份有限公司 | 一种制备咪达普利关键中间体及其衍生物的方法 |
JOP20210193A1 (ar) | 2019-01-18 | 2023-01-30 | Astrazeneca Ab | مثبطات pcsk9 وطرق استخدامها |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL58849A (en) * | 1978-12-11 | 1983-03-31 | Merck & Co Inc | Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them |
GR75019B (xx) * | 1980-09-17 | 1984-07-12 | Univ Miami | |
US4296110A (en) * | 1980-10-28 | 1981-10-20 | E. I. Du Pont De Nemours And Company | Antihypertensive I-substituted cyclic lactam-2-carboxylic acids |
JPS5788165A (en) * | 1980-11-21 | 1982-06-01 | Tanabe Seiyaku Co Ltd | 2-oxoimidazolidine-4-carboxylic acid derivative and its preparation |
JPS5835114A (ja) * | 1981-08-21 | 1983-03-01 | ザ・ユニバ−シイテイ・オブ・マイアミ | 抗高血圧剤 |
-
1982
- 1982-05-24 JP JP57088637A patent/JPS6058233B2/ja not_active Expired
-
1983
- 1983-05-20 EP EP83105024A patent/EP0095163B1/en not_active Expired
- 1983-05-20 DE DE8383105024T patent/DE3373100D1/de not_active Expired
- 1983-05-20 DE DE1999175013 patent/DE19975013I1/de active Pending
- 1983-05-24 US US06/496,877 patent/US4508727A/en not_active Expired - Lifetime
- 1983-05-24 ES ES522678A patent/ES522678A0/es active Granted
-
1984
- 1984-09-17 ES ES535980A patent/ES8603427A1/es not_active Expired
-
1987
- 1987-06-09 MY MYPI87000783A patent/MY100095A/en unknown
-
1989
- 1989-02-03 SG SG59/89A patent/SG5989G/en unknown
- 1989-04-20 HK HK326/89A patent/HK32689A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ES535980A0 (es) | 1985-12-16 |
JPS6058233B2 (ja) | 1985-12-19 |
ES8603427A1 (es) | 1985-12-16 |
SG5989G (en) | 1989-06-09 |
EP0095163A2 (en) | 1983-11-30 |
US4508727A (en) | 1985-04-02 |
ES8503667A1 (es) | 1985-03-16 |
EP0095163A3 (en) | 1984-09-12 |
JPS58203971A (ja) | 1983-11-28 |
EP0095163B1 (en) | 1987-08-19 |
MY100095A (en) | 1989-10-10 |
DE3373100D1 (en) | 1987-09-24 |
DE19975013I1 (de) | 2003-09-04 |
ES522678A0 (es) | 1985-03-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PE | Patent expired |