HK1256305A1 - 人非小細胞肺癌中的易位和突變的ros激酶 - Google Patents

人非小細胞肺癌中的易位和突變的ros激酶

Info

Publication number
HK1256305A1
HK1256305A1 HK18115370.8A HK18115370A HK1256305A1 HK 1256305 A1 HK1256305 A1 HK 1256305A1 HK 18115370 A HK18115370 A HK 18115370A HK 1256305 A1 HK1256305 A1 HK 1256305A1
Authority
HK
Hong Kong
Prior art keywords
translocation
small cell
cell lung
lung carcinoma
human non
Prior art date
Application number
HK18115370.8A
Other languages
English (en)
Inventor
Anthony Possemato
Ailan Guo
Original Assignee
Cell Signaling Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38288244&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1256305(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cell Signaling Technology Inc filed Critical Cell Signaling Technology Inc
Publication of HK1256305A1 publication Critical patent/HK1256305A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Mycology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
HK18115370.8A 2006-01-20 2018-11-30 人非小細胞肺癌中的易位和突變的ros激酶 HK1256305A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76063406P 2006-01-20 2006-01-20

Publications (1)

Publication Number Publication Date
HK1256305A1 true HK1256305A1 (zh) 2019-09-20

Family

ID=38288244

Family Applications (2)

Application Number Title Priority Date Filing Date
HK09100200.7A HK1120272A1 (zh) 2006-01-20 2009-01-08 人類非小細胞肺癌中的易位和突變體 激酶
HK18115370.8A HK1256305A1 (zh) 2006-01-20 2018-11-30 人非小細胞肺癌中的易位和突變的ros激酶

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK09100200.7A HK1120272A1 (zh) 2006-01-20 2009-01-08 人類非小細胞肺癌中的易位和突變體 激酶

Country Status (10)

Country Link
EP (4) EP3360965A1 (zh)
JP (7) JP5554925B2 (zh)
CN (2) CN101528921B (zh)
DK (2) DK1973946T3 (zh)
ES (2) ES2539830T3 (zh)
HK (2) HK1120272A1 (zh)
HU (1) HUE039085T2 (zh)
PT (1) PT2671954T (zh)
SI (1) SI2671954T1 (zh)
WO (1) WO2007084631A2 (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120208824A1 (en) 2006-01-20 2012-08-16 Cell Signaling Technology, Inc. ROS Kinase in Lung Cancer
US8383799B2 (en) 2006-01-20 2013-02-26 Cell Signaling Technology, Inc. Translocation and mutant ROS kinase in human non-small cell lung carcinoma
DK1973946T3 (da) * 2006-01-20 2015-06-22 Cell Signaling Technology Inc Translokation og mutant ros kinase i human ikke-småcellet lungekarcinom
JP5769968B2 (ja) 2007-10-18 2015-08-26 セル・シグナリング・テクノロジー・インコーポレイテツド ヒト非小細胞肺癌における転座および変異ｒｏｓキナーゼ
JP5979877B2 (ja) 2009-02-12 2016-08-31 セル・シグナリング・テクノロジー・インコーポレイテツド ヒト癌における変異ｒｏｓ発現
US9109259B2 (en) 2010-06-22 2015-08-18 Japanese Foundation For Cancer Research Detection method for novel ROS1 fusions
KR20140041906A (ko) 2011-08-02 2014-04-04 화이자 인코포레이티드 암의 치료에 사용하기 위한 크리조티닙
JP2015508644A (ja) * 2012-02-08 2015-03-23 インサイト ジェネティクス インコーポレイテッド 癌の診断および治療のためのｒｏｓ１の融合体に関する方法および組成物
EP3071706B1 (en) * 2013-11-21 2018-04-25 Assistance Publique-Hôpitaux de Paris Method for detecting chromosomal rearrangements
CN107236818A (zh) * 2017-07-19 2017-10-10 臻悦生物科技江苏有限公司 肺癌临床用药突变基因检测试剂盒
CN111094582A (zh) * 2017-08-09 2020-05-01 帕姆基因有限公司 预测非小细胞肺癌患者对药物的反应的方法
CN108148912B (zh) * 2018-03-08 2021-10-08 四川大学 肿瘤的生物标志物、应用和肿瘤检测试剂盒
US20220227889A1 (en) * 2019-04-30 2022-07-21 Encodia, Inc. Methods and reagents for cleavage of the n-terminal amino acid from a polypeptide
CN110655080B (zh) * 2019-10-25 2022-08-05 山东大学 一种具有选择性杀灭癌细胞功能的无氧化Ti3C2量子点及其制备方法与应用

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Also Published As

Publication number Publication date
CN103981198B (zh) 2020-09-01
CN101528921A (zh) 2009-09-09
EP1973946A2 (en) 2008-10-01
JP7262214B2 (ja) 2023-04-21
JP6957546B2 (ja) 2021-11-02
EP2671954B1 (en) 2018-05-16
PT2671954T (pt) 2018-10-08
EP1973946A4 (en) 2010-08-11
JP6521928B2 (ja) 2019-05-29
DK1973946T3 (da) 2015-06-22
EP1973946B1 (en) 2015-03-25
JP5554925B2 (ja) 2014-07-23
EP2671954A3 (en) 2014-02-12
JP2019068816A (ja) 2019-05-09
ES2683846T3 (es) 2018-09-28
DK2671954T3 (en) 2018-08-13
CN103981198A (zh) 2014-08-13
WO2007084631A3 (en) 2008-12-31
JP2023039988A (ja) 2023-03-22
SI2671954T1 (sl) 2018-11-30
JP6259320B2 (ja) 2018-01-10
CN101528921B (zh) 2013-11-20
JP2021006039A (ja) 2021-01-21
HK1120272A1 (zh) 2009-03-27
JP2019141060A (ja) 2019-08-29
JP2014140371A (ja) 2014-08-07
EP2671954A2 (en) 2013-12-11
EP3936621A1 (en) 2022-01-12
EP3360965A1 (en) 2018-08-15
WO2007084631A2 (en) 2007-07-26
JP2009523446A (ja) 2009-06-25
HUE039085T2 (hu) 2018-12-28
ES2539830T3 (es) 2015-07-06
JP2017070286A (ja) 2017-04-13

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