HK1252674A1 - 在肺癌診斷中的mirna指紋 - Google Patents
在肺癌診斷中的mirna指紋Info
- Publication number
- HK1252674A1 HK1252674A1 HK18111981.8A HK18111981A HK1252674A1 HK 1252674 A1 HK1252674 A1 HK 1252674A1 HK 18111981 A HK18111981 A HK 18111981A HK 1252674 A1 HK1252674 A1 HK 1252674A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- diagnosis
- lung cancer
- mirna fingerprint
- mirna
- fingerprint
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/20—Supervised data analysis
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/30—Unsupervised data analysis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Data Mining & Analysis (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Databases & Information Systems (AREA)
- Epidemiology (AREA)
- Evolutionary Computation (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Bioethics (AREA)
- Artificial Intelligence (AREA)
- Public Health (AREA)
- Software Systems (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18445209P | 2009-06-05 | 2009-06-05 | |
US21397109P | 2009-08-03 | 2009-08-03 | |
US28752109P | 2009-12-17 | 2009-12-17 | |
EP09015668A EP2336353A1 (en) | 2009-12-17 | 2009-12-17 | miRNA fingerprints in the diagnosis of diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1252674A1 true HK1252674A1 (zh) | 2019-05-31 |
Family
ID=42470815
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18111981.8A HK1252674A1 (zh) | 2009-06-05 | 2018-09-18 | 在肺癌診斷中的mirna指紋 |
Country Status (10)
Country | Link |
---|---|
US (7) | US9187785B2 (zh) |
EP (9) | EP2336353A1 (zh) |
DK (1) | DK2883966T3 (zh) |
ES (1) | ES2642395T3 (zh) |
HK (1) | HK1252674A1 (zh) |
HU (1) | HUE035009T2 (zh) |
NO (1) | NO2883966T3 (zh) |
PL (1) | PL2883966T3 (zh) |
PT (1) | PT2883966T (zh) |
WO (3) | WO2010139812A1 (zh) |
Families Citing this family (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008147974A1 (en) | 2007-05-23 | 2008-12-04 | University Of South Florida | Micro-rnas modulating immunity and inflammation |
US20100233704A1 (en) * | 2009-02-25 | 2010-09-16 | Cepheid | Methods of detecting lung cancer |
EP2422298A4 (en) * | 2009-04-24 | 2014-09-03 | Virkar Hemant | METHOD FOR DATA MAPPING IN SMALLER DIMENSIONS |
EP2336353A1 (en) * | 2009-12-17 | 2011-06-22 | febit holding GmbH | miRNA fingerprints in the diagnosis of diseases |
WO2011076144A1 (en) * | 2009-12-24 | 2011-06-30 | Fudan University | Compositions and methods for microrna expession profiling in plasma of lung cancer |
US20120015830A1 (en) * | 2010-06-21 | 2012-01-19 | Diogenix, Inc. | Microrna profiles for evaluating multiple sclerosis |
CN103168235B (zh) | 2010-07-16 | 2016-01-13 | 阿姆斯特丹自由大学及阿姆斯特丹自由大学医疗中心基金会 | 用于分析受试者血样中疾病标记物的存在的方法 |
US20120107825A1 (en) * | 2010-11-01 | 2012-05-03 | Winger Edward E | Methods and compositions for assessing patients with reproductive failure using immune cell-derived microrna |
US20130310276A1 (en) * | 2010-12-22 | 2013-11-21 | Ruprecht-Karls University of Heidelberg | Microrna for diagnosis of pancreatic cancer |
CN102127548A (zh) * | 2010-12-28 | 2011-07-20 | 浙江大学 | 单链非编码MicroRNA二及其用途 |
EP2505663A1 (en) * | 2011-03-30 | 2012-10-03 | IFOM Fondazione Istituto Firc di Oncologia Molecolare | A method to identify asymptomatic high-risk individuals with early stage lung cancer by means of detecting miRNAs in biologic fluids |
US20120244530A1 (en) | 2011-01-26 | 2012-09-27 | Cepheid | Methods of detecting lung cancer |
US20120214682A1 (en) * | 2011-01-28 | 2012-08-23 | Bigwood Douglas W | Microrna signatures indicative of immunomodulating therapy for multiple sclerosis |
US20130331290A1 (en) * | 2011-01-28 | 2013-12-12 | Febit Holding Gmbh | Complex mirna sets as novel biomarkers for lung diseases |
CN102643812B (zh) * | 2011-02-18 | 2016-02-10 | 中国科学院上海药物研究所 | 人miR-1227的反义寡聚核苷酸及其应用 |
JP5934726B2 (ja) * | 2011-03-18 | 2016-06-15 | フェレニヒング フォール クリステリック ホーヘル オンデルウィス,ウェテンシャペリク オンデルツォーケン パティエンテンツォルフ | 疾患マーカーの存在を被験者の血液サンプルで分析する方法 |
WO2012135091A2 (en) * | 2011-03-28 | 2012-10-04 | The Johns Hopkins University | Serum-based mirna microarray and its use in diagnosis and treatment of barrett's esophagus (be) and esophageal adenocarcinoma (eac) |
WO2012161124A1 (ja) * | 2011-05-20 | 2012-11-29 | 国立大学法人愛媛大学 | マイクロrna又はその発現系を含む組成物 |
EP2718463B1 (en) * | 2011-06-08 | 2016-01-20 | Comprehensive Biomarker Center GmbH | Complex sets of mirnas as non-invasive biomarkers for dilated cardiomyopathy |
CN102851282B (zh) * | 2011-06-30 | 2014-10-08 | 上海市肿瘤研究所 | 用于区分原发性肺癌与癌旁组织的microRNA标志物 |
CN102250904B (zh) * | 2011-07-13 | 2013-11-13 | 中国科学技术大学 | 一种预防和/或治疗黑色素瘤的药物 |
DE102011108254A1 (de) * | 2011-07-22 | 2013-01-24 | RUHR-UNIVERSITäT BOCHUM | Pantumormarker |
US20130059753A1 (en) * | 2011-09-01 | 2013-03-07 | Holy and Undivided Trinity of Queen Elizabeth, near Dublin | Global Analysis of Serum microRNAs as Potential Biomarkers for Lung Adenocarcinoma |
EP2578696A1 (en) * | 2011-10-06 | 2013-04-10 | febit holding GmbH | MiRNAs as non-invasive biomarkers for diagnosis |
GB2536374B (en) * | 2011-10-19 | 2016-10-26 | Council Scient Ind Res | Biomarkers useful for detection of types, grades and stages of human breast cancer |
NO3051026T3 (zh) * | 2011-10-21 | 2018-07-28 | ||
US9745578B2 (en) | 2011-11-30 | 2017-08-29 | Cedars-Sinai Medical Center | Targeting microRNA miR-409-3P to treat prostate cancer |
CA2799163A1 (en) | 2011-12-18 | 2013-06-18 | 20/20 Genesystems, Inc. | Methods and algorithms for aiding in the detection of cancer |
US9447471B2 (en) | 2011-12-29 | 2016-09-20 | Quest Diagnostics Investments Incorporated | Microrna profiling for diagnosis of dysplastic nevi and melanoma |
WO2013106766A2 (en) * | 2012-01-13 | 2013-07-18 | The Research Foundation Of State University Of New York | THERAPEUTIC INDICATIONS OF miR-1291 |
WO2013104131A1 (zh) * | 2012-01-13 | 2013-07-18 | 北京命码生科科技有限公司 | microRNA标准化的内参基因及其用途 |
EP3360977A3 (en) * | 2012-03-07 | 2018-10-10 | Hummingbird Diagnostics GmbH | Mi-rna based treatment monitoring in multiple sclerosis |
WO2013131567A1 (en) * | 2012-03-07 | 2013-09-12 | Febit Holding Gmbh | Mirna based treatment monitoring in multiple sclerosis |
WO2013155980A1 (zh) * | 2012-04-19 | 2013-10-24 | 中国科学院上海生命科学研究院 | 自身免疫性疾病相关的microRNA及其应用 |
EP2657348B1 (en) * | 2012-04-27 | 2017-11-15 | Siemens Aktiengesellschaft | Diagnostic miRNA profiles in multiple sclerosis |
US8846316B2 (en) | 2012-04-30 | 2014-09-30 | Industrial Technology Research Institute | Biomarker for human liver cancer |
US20150126621A1 (en) * | 2012-05-15 | 2015-05-07 | New York University | METHOD FOR PREDICTING RECURRENCE OF MELANOMA USING miRNA ALTERATIONS |
CN102676526B (zh) * | 2012-05-16 | 2013-05-29 | 北京旷博生物技术有限公司 | 乳腺癌分子标志物miR-30c-1-3p |
DK2687607T3 (en) | 2012-07-19 | 2015-04-07 | St Josef Und St Elisabeth Hospital Gmbh | MicroRNA-profiles in the diagnosis of multiple sclerosis |
US20150232939A1 (en) * | 2012-10-26 | 2015-08-20 | Gabriella Sozzi | Micro-rna biomarkers for haemolysis and methods of using same |
CN103045597B (zh) * | 2013-01-11 | 2014-06-11 | 南京大学 | 微小核苷酸hsa-miR-1909及其应用 |
CN103305602A (zh) * | 2013-03-08 | 2013-09-18 | 深圳市人民医院 | 一种基于液相芯片检测痰液microRNAs用于早期肺癌诊断的方法 |
KR20150069375A (ko) * | 2013-12-13 | 2015-06-23 | 연세대학교 산학협력단 | 줄기세포로부터 연골세포로의 분화 촉진용 조성물 |
EP3760741A1 (en) * | 2013-12-19 | 2021-01-06 | Hummingbird Diagnostics GmbH | Mirnas as non-invasive biomarkers for parkinson's disease |
ES2936812T3 (es) * | 2013-12-20 | 2023-03-22 | Acetylon Pharmaceuticals Inc | Biomarcadores de histona desacetilasa 6 (HDAC6) en mieloma múltiple |
PL406989A1 (pl) | 2014-01-29 | 2015-08-03 | Gdański Uniwersytet Medyczny | Profil mikro RNA we krwi jako test wykrywania raka płuca |
RU2017101354A (ru) * | 2014-06-18 | 2018-07-18 | Торэй Индастриз, Инк. | Набор или устройство для обнаружения рака легкого и способ обнаружения |
WO2016094330A2 (en) * | 2014-12-08 | 2016-06-16 | 20/20 Genesystems, Inc | Methods and machine learning systems for predicting the liklihood or risk of having cancer |
JP6974182B2 (ja) * | 2015-03-04 | 2021-12-01 | ハミングバード・ダイアグノスティクス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングHummingbird Diagnostics GmbH | 健康のサイン |
PL411561A1 (pl) | 2015-03-13 | 2016-09-26 | Gdański Uniwersytet Medyczny | Profil mikroRNA skojarzony z profilem markerów białkowych krwi jako test wykrywania raka płuca |
CN104789683B (zh) * | 2015-05-01 | 2018-08-28 | 北京博奥医学检验所有限公司 | 用于诊治癌转移的生物标志物及其用途 |
EP3292213A1 (en) | 2015-05-04 | 2018-03-14 | Academisch Medisch Centrum | Biomarkers for the detection of aspirin insensitivity |
KR102552776B1 (ko) * | 2015-11-30 | 2023-07-10 | (주)아모레퍼시픽 | miRNA를 포함하는 흑색종 전이 억제용 조성물 |
EP3184645A1 (de) | 2015-12-22 | 2017-06-28 | Siemens Healthcare GmbH | Diagnostische mirna signaturen in ms und cis patienten |
JPWO2017110687A1 (ja) * | 2015-12-24 | 2018-10-18 | 公益財団法人がん研究会 | miRNAにより肺癌の原因を特定する方法、マーカー、検出キット、及び治療薬をスクリーニングするための方法 |
US20190112668A1 (en) * | 2016-04-01 | 2019-04-18 | Toray Industries, Inc. | Kit or device for detecting malignant brain tumor and method for detecting same |
US20210095342A1 (en) * | 2016-05-09 | 2021-04-01 | The Children's Hospital Of Philadelphia | Functional targets of mir-6891-5p & applications thereof |
WO2018041726A1 (en) | 2016-08-27 | 2018-03-08 | Academisch Medisch Centrum | Biomarkers for determining the presence of an unstable atherosclerotic plaque |
KR101721811B1 (ko) * | 2016-12-28 | 2017-03-30 | 경북대학교 산학협력단 | microRNA-30b, microRNA-133a 또는 microRNA-202-5p의 억제제를 포함하는 항암용 약학적 조성물 |
US10733214B2 (en) | 2017-03-20 | 2020-08-04 | International Business Machines Corporation | Analyzing metagenomics data |
US11535895B2 (en) | 2017-04-06 | 2022-12-27 | University Of Maryland, Baltimore | Methods of detecting lung cancer |
KR20200019849A (ko) | 2017-06-29 | 2020-02-25 | 도레이 카부시키가이샤 | 폐암의 검출을 위한 키트, 디바이스 및 방법 |
WO2019000017A1 (en) * | 2017-06-29 | 2019-01-03 | The University Of Sydney | INTRACELLULAR MICRO-RNA SIGNATURES OF INSULIN-PRODUCING CELLS |
US20200239967A1 (en) * | 2017-10-03 | 2020-07-30 | Geneseq Pty. Ltd. | Method of diagnosis, staging and monitoring of melanoma using microrna gene expression |
CN109706146B (zh) * | 2017-10-25 | 2023-06-06 | 上海翔琼生物技术有限公司 | 小rna组成的指纹图谱在人的癌性胸腔积液诊断和治疗中的应用 |
CN109288361B (zh) * | 2018-10-10 | 2020-05-12 | 童小鸾 | 一种服装机械用的衣架 |
CN109207599A (zh) * | 2018-11-12 | 2019-01-15 | 觅瑞(杭州)生物科技有限公司 | 一种用于非小细胞肺癌诊断的外周血miRNA标志物 |
CN109224076B (zh) * | 2018-11-14 | 2021-11-19 | 苏州吉玛基因股份有限公司 | 与肺癌诊疗相关的基因miR-140-3P及其mimics和应用 |
CN111197070A (zh) * | 2018-11-16 | 2020-05-26 | 南京迈西可生物科技有限公司 | 鉴定rna分子中2`-o-甲基化修饰的方法及其应用 |
US11948684B2 (en) * | 2019-06-20 | 2024-04-02 | Latha Chakravarthy | Diagnostic process for disease detection using gene expression based multi layer PCA classifier |
EP4257982A3 (en) * | 2019-08-26 | 2024-03-06 | Liquid Lung DX | Biomarkers for the diagnosis of lung cancers |
JP7473941B2 (ja) * | 2019-11-07 | 2024-04-24 | 学校法人産業医科大学 | 中皮腫の診断補助方法及び診断用キット |
KR102288359B1 (ko) * | 2019-12-06 | 2021-08-10 | 주식회사 레피겐엠디 | 면역력 감소에 의한 질병의 발병 위험 예측용 다중 유전자 마커 및 이를 이용한 질병의 발병 위험 예측 방법 |
EP3862441A3 (en) * | 2020-02-04 | 2021-10-27 | Artemisia S.p.A. | Method for the early diagnosis of cancer by means of ddpcr analysis of mirna and protein markers in liquid biopsy |
EP3862442A3 (en) * | 2020-02-04 | 2021-10-27 | Artemisia S.p.A. | Method for the early diagnosis of cancer by means of ddpcr analysis of mirna in liquid biopsy |
CN112501295B (zh) * | 2020-12-01 | 2023-03-31 | 上海米然生物科技有限公司 | miRNA组合、含其的试剂盒及在肺癌诊断中的应用 |
CN111793692A (zh) * | 2020-08-04 | 2020-10-20 | 中国科学院昆明动物研究所 | 一种特征miRNA表达谱组合及肺鳞癌早期预测方法 |
US20220073992A1 (en) * | 2020-11-24 | 2022-03-10 | Hossein Abdul Tehrani Abdul Tehrani | Diagnosis of chronic kidney disease (ckd) and its subgroups |
RU2755651C1 (ru) * | 2020-12-21 | 2021-09-17 | федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина» Министерства здравоохранения Российской Федерации (ФГБУ «НМИЦ им. ак. Е.Н. Мешалкина» Минздрава России) | Аналитическая система для диагностики рака лёгкого при помощи свободных и ассоциированных с клетками крови циркулирующих микроРНК |
EP4355882A2 (en) * | 2021-06-15 | 2024-04-24 | Modernatx, Inc. | Engineered polynucleotides for cell-type or microenvironment-specific expression |
WO2024002599A1 (en) * | 2022-06-28 | 2024-01-04 | Hummingbird Diagnostics Gmbh | Novel signatures for lung cancer detection |
WO2024009221A1 (en) * | 2022-07-04 | 2024-01-11 | Artificial Intelligence Expert Srl | Method and system for multi-cancer management in subject |
CN115820858B (zh) * | 2022-11-18 | 2023-06-20 | 昆明医科大学第一附属医院 | 一种血清在制备云南宣威肺癌诊断药物中的应用 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020168640A1 (en) * | 2001-02-22 | 2002-11-14 | Min Li | Biochips comprising nucleic acid/protein conjugates |
US20030186248A1 (en) * | 2002-03-29 | 2003-10-02 | Erlander Mark G. | Interpreting cytological specimens via molecular histological signatures |
EP2322650A1 (en) * | 2004-05-14 | 2011-05-18 | Rosetta Genomics Ltd | MicroRNAs and uses thereof |
EP2290069A3 (en) | 2004-05-28 | 2011-08-10 | Asuragen, Inc. | Methods and compositions involving microRNA |
US20060019258A1 (en) * | 2004-07-20 | 2006-01-26 | Illumina, Inc. | Methods and compositions for detection of small interfering RNA and micro-RNA |
ES2536438T3 (es) * | 2006-01-05 | 2015-05-25 | The Ohio State University Research Foundation | Métodos y composiciones basados en los microARN para el diagnóstico, pronóstico y tratamiento del cáncer de pulmón |
AU2007299748A1 (en) * | 2006-09-19 | 2008-03-27 | Asuragen, Inc. | miR-15, miR-26, miR -31,miR -145, miR-147, miR-188, miR-215, miR-216 miR-331, mmu-miR-292-3p regulated genes and pathways as targets for therapeutic intervention |
CA2669600A1 (en) * | 2006-11-13 | 2008-05-29 | Source Precision Medicine, Inc. D/B/A Source Mdx | Gene expression profiling for identification, monitoring, and treatment of lung cancer |
US20120064520A1 (en) | 2007-03-01 | 2012-03-15 | Ranit Aharonov | Diagnosis and prognosis of various types of cancers |
US20100178653A1 (en) | 2007-03-27 | 2010-07-15 | Rosetta Genomics Ltd. | Gene expression signature for classification of cancers |
EP2188395A4 (en) | 2007-08-17 | 2010-10-13 | Catalyst Assets Llc | USE OF MICRO-RNA ASSOCIATED WITH CANCER OF THE HUMAN BLADDER FOR DIAGNOSIS AND PROGNOSIS |
WO2009033185A1 (en) * | 2007-09-06 | 2009-03-12 | University Of Massachusetts | Virus-specific mirna signatures for diagnosis and therapeutic treatment of viral infection |
EP3112464A1 (en) * | 2007-09-14 | 2017-01-04 | The Ohio State University Research Foundation | Mirna expression in human peripheral blood microvesicles and uses thereof |
WO2009036332A1 (en) * | 2007-09-14 | 2009-03-19 | Asuragen, Inc. | Micrornas differentially expressed in cervical cancer and uses thereof |
CA2700215A1 (en) | 2007-10-31 | 2009-05-07 | Rosetta Genomics Ltd. | Diagnosis and prognosis of specific cancers |
CN101424640B (zh) | 2007-11-02 | 2012-07-25 | 江苏命码生物科技有限公司 | 血清中微小核糖核酸的检测方法和用于检测的试剂盒、生物芯片及其制作和应用方法 |
AU2008329755A1 (en) * | 2007-11-30 | 2009-06-04 | The Ohio State University Research Foundation | MicroRNA expression profiling and targeting in peripheral blood in lung cancer |
WO2009099905A2 (en) | 2008-02-01 | 2009-08-13 | Memorial Health Inc. | Molecular signatures and biomarkers associated with melanoma and methods of use thereof |
CA2717030A1 (en) * | 2008-02-28 | 2009-09-03 | The Ohio State University Research Foundation | Microrna signatures associated with cytogenetics and prognosis in acute myeloid leukemia (aml) and uses thereof |
US20110160290A1 (en) * | 2008-05-21 | 2011-06-30 | Muneesh Tewari | Use of extracellular rna to measure disease |
US20110107440A1 (en) | 2008-06-04 | 2011-05-05 | Andor Pivarcsi | Skin cancer associated micrornas |
WO2010054233A1 (en) * | 2008-11-08 | 2010-05-14 | The Wistar Institute Of Anatomy And Biology | Biomarkers in peripheral blood mononuclear cells for diagnosing or detecting lung cancers |
CN101475984A (zh) | 2008-12-15 | 2009-07-08 | 江苏命码生物科技有限公司 | 一种非小细胞肺癌检测标记物及其检测方法、相关生物芯片和试剂盒 |
EP2336353A1 (en) * | 2009-12-17 | 2011-06-22 | febit holding GmbH | miRNA fingerprints in the diagnosis of diseases |
-
2009
- 2009-12-17 EP EP09015668A patent/EP2336353A1/en not_active Withdrawn
-
2010
- 2010-06-07 WO PCT/EP2010/057944 patent/WO2010139812A1/en active Application Filing
- 2010-06-07 PT PT141963108T patent/PT2883966T/pt unknown
- 2010-06-07 EP EP10722117.8A patent/EP2438188B1/en active Active
- 2010-06-07 EP EP10722116.0A patent/EP2438187B1/en not_active Not-in-force
- 2010-06-07 EP EP14196310.8A patent/EP2883966B1/en active Active
- 2010-06-07 DK DK14196310.8T patent/DK2883966T3/en active
- 2010-06-07 NO NO14196310A patent/NO2883966T3/no unknown
- 2010-06-07 US US13/376,243 patent/US9187785B2/en active Active
- 2010-06-07 HU HUE14196310A patent/HUE035009T2/en unknown
- 2010-06-07 US US13/376,225 patent/US9194002B2/en active Active
- 2010-06-07 EP EP17155238.3A patent/EP3184651B1/en active Active
- 2010-06-07 WO PCT/EP2010/057943 patent/WO2010139811A1/en active Application Filing
- 2010-06-07 EP EP16182589.8A patent/EP3112479A1/en active Pending
- 2010-06-07 EP EP10724072.3A patent/EP2438190B1/en active Active
- 2010-06-07 EP EP20151428.8A patent/EP3683320A3/en not_active Withdrawn
- 2010-06-07 PL PL14196310T patent/PL2883966T3/pl unknown
- 2010-06-07 EP EP17185100.9A patent/EP3296406B1/en active Active
- 2010-06-07 ES ES14196310.8T patent/ES2642395T3/es active Active
- 2010-06-07 US US13/376,281 patent/US9758827B2/en active Active
- 2010-06-07 WO PCT/EP2010/057942 patent/WO2010139810A1/en active Application Filing
-
2015
- 2015-09-28 US US14/867,174 patent/US9702008B2/en active Active
- 2015-10-02 US US14/873,385 patent/US10000810B2/en active Active
-
2017
- 2017-08-08 US US15/671,856 patent/US20180087111A1/en not_active Abandoned
-
2018
- 2018-09-18 HK HK18111981.8A patent/HK1252674A1/zh unknown
-
2021
- 2021-08-03 US US17/392,534 patent/US20220042102A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1252674A1 (zh) | 在肺癌診斷中的mirna指紋 | |
ZA201207574B (en) | Phytocannabinoids in the treatment of cancer | |
IL223295A0 (en) | Lung cancer biomarkers and uses thereof | |
HK1204062A1 (zh) | 肺癌生物標記及其用途 | |
HK1175476A1 (zh) | 癌症治療 | |
EP2470897A4 (en) | MICRO-RNA BIOMARKERS OF PULMONARY DISEASE | |
EP2401406A4 (en) | METHODS OF DETECTING LUNG CANCER | |
GB0922085D0 (en) | Cancer diagnosis and treatment | |
GB2467840B (en) | Disease determination | |
IL264349B1 (en) | Regimens containing neratinib for the treatment of cancer | |
HUP0900819A2 (en) | Lung tissue culture | |
EP2457092A4 (en) | CANCER BIOMARKERS AND THEIR USE | |
GB0918392D0 (en) | Diagnostic and therapeutic methods | |
EP2361317A4 (en) | USE OF EIF3M FOR THE DIAGNOSIS AND TREATMENT OF CANCER | |
GB0901837D0 (en) | Cancer diagnosis and treatment | |
GB0902537D0 (en) | Improvememts in or relating to the creation of curved forms | |
EP2403341A4 (en) | LUNGENKREBSBEHNDLUNG | |
GB0914738D0 (en) | Inhalers | |
EP2473613A4 (en) | KREBSAUSHUNGERUNGSTHERAPIE | |
GB0902538D0 (en) | Improvvements in or relating to the creation of curved forms | |
EP2321641A4 (en) | GENE METHYLATION IN THE DIAGNOSIS OF CANCER | |
GB0907098D0 (en) | Cancer treatment and diagnosis | |
GB0811923D0 (en) | Lung cancer diagnosis, prognistication and treatment | |
GB0807998D0 (en) | Cancer diagnostic LIMD1 | |
GB0902539D0 (en) | Improvements in or relating to the creation of curved forms |