HK1249914A1 - 能夠在人脂肪衍生的幹細胞和肝細胞中抑制丙肝病毒複製的肽及其衍生物 - Google Patents

能夠在人脂肪衍生的幹細胞和肝細胞中抑制丙肝病毒複製的肽及其衍生物

Info

Publication number
HK1249914A1
HK1249914A1 HK18109405.0A HK18109405A HK1249914A1 HK 1249914 A1 HK1249914 A1 HK 1249914A1 HK 18109405 A HK18109405 A HK 18109405A HK 1249914 A1 HK1249914 A1 HK 1249914A1
Authority
HK
Hong Kong
Prior art keywords
hepatocytes
hepatitis
virus
peptide
stem cells
Prior art date
Application number
HK18109405.0A
Other languages
English (en)
Inventor
Chen-Lung Lin
Original Assignee
Inno Bio Drug Development Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inno Bio Drug Development Ltd filed Critical Inno Bio Drug Development Ltd
Publication of HK1249914A1 publication Critical patent/HK1249914A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK18109405.0A 2015-04-16 2018-07-20 能夠在人脂肪衍生的幹細胞和肝細胞中抑制丙肝病毒複製的肽及其衍生物 HK1249914A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2015/076744 WO2016165101A1 (en) 2015-04-16 2015-04-16 Peptide and its derivatives capable of inhibiting replication of hepatitis c virus in human adipose-derived stem cells and hepatocytes

Publications (1)

Publication Number Publication Date
HK1249914A1 true HK1249914A1 (zh) 2018-11-16

Family

ID=57125559

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18109405.0A HK1249914A1 (zh) 2015-04-16 2018-07-20 能夠在人脂肪衍生的幹細胞和肝細胞中抑制丙肝病毒複製的肽及其衍生物

Country Status (9)

Country Link
US (1) US11254706B2 (zh)
EP (1) EP3283503B1 (zh)
JP (1) JP2018516272A (zh)
KR (1) KR20170137184A (zh)
CN (1) CN107849091B (zh)
AU (1) AU2015391060A1 (zh)
CA (1) CA2982391A1 (zh)
HK (1) HK1249914A1 (zh)
WO (1) WO2016165101A1 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020024142A1 (en) * 2018-08-01 2020-02-06 Vanford Bio-Drug Development Limited Novel peptides and its derivatives capable of stimulating cytokine release
TWI705818B (zh) * 2019-10-18 2020-10-01 沛爾生技醫藥股份有限公司 肽及其作為製備治療發炎性疾病及疼痛的藥物的用途
EP4047007B1 (en) * 2019-10-18 2024-06-05 Pell Bio-Med Technology Co., Ltd. Peptide and use thereof in preparation of drug for treating inflammatory diseases and pain
CN112759625B (zh) * 2019-10-18 2023-05-05 沛尔生技医药股份有限公司 肽作为制备治疗发炎性疾病及疼痛的药物的用途
WO2023184473A1 (zh) * 2022-04-01 2023-10-05 首创生物技术有限公司 肽用于治疗神经退行性疾病或改善认知功能的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006130553A2 (en) * 2005-06-02 2006-12-07 Schering Corporation Hcv protease inhibitors
KR100794362B1 (ko) * 2006-02-27 2008-01-15 주식회사 임젠 Ｎａｎｏｇ를 이용한 아스트로사이트의 신경줄기세포로의역분화
GB0907698D0 (en) * 2009-05-05 2009-06-10 Univ Singapore Method of modifying serine protease inhibitors
CN104321337B (zh) * 2012-05-25 2017-07-11 永林有限公司 肽及其用途

Also Published As

Publication number Publication date
AU2015391060A1 (en) 2017-10-26
EP3283503A1 (en) 2018-02-21
EP3283503B1 (en) 2020-08-19
WO2016165101A1 (en) 2016-10-20
CA2982391A1 (en) 2016-10-20
KR20170137184A (ko) 2017-12-12
EP3283503A4 (en) 2018-11-14
CN107849091B (zh) 2021-09-10
US11254706B2 (en) 2022-02-22
JP2018516272A (ja) 2018-06-21
US20180134751A1 (en) 2018-05-17
CN107849091A (zh) 2018-03-27

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