HK1245675A1 - 多價人免疫缺陷病毒抗原結合分子及其用途 - Google Patents
多價人免疫缺陷病毒抗原結合分子及其用途Info
- Publication number
- HK1245675A1 HK1245675A1 HK18105481.5A HK18105481A HK1245675A1 HK 1245675 A1 HK1245675 A1 HK 1245675A1 HK 18105481 A HK18105481 A HK 18105481A HK 1245675 A1 HK1245675 A1 HK 1245675A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- antigen binding
- binding molecules
- immunodeficiency virus
- human immunodeficiency
- virus antigen
- Prior art date
Links
- 241000725303 Human immunodeficiency virus Species 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/35—Valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/522—CH1 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562149460P | 2015-04-17 | 2015-04-17 | |
PCT/US2016/027979 WO2016168758A1 (en) | 2015-04-17 | 2016-04-15 | Multi-valent human immunodeficiency virus antigen binding molecules and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1245675A1 true HK1245675A1 (zh) | 2018-08-31 |
Family
ID=57126939
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18105481.5A HK1245675A1 (zh) | 2015-04-17 | 2018-04-27 | 多價人免疫缺陷病毒抗原結合分子及其用途 |
Country Status (8)
Country | Link |
---|---|
US (2) | US10570191B2 (zh) |
EP (1) | EP3283112A4 (zh) |
JP (1) | JP6811723B2 (zh) |
CN (1) | CN107847591B (zh) |
AU (1) | AU2016249404B2 (zh) |
CA (1) | CA2983034A1 (zh) |
HK (1) | HK1245675A1 (zh) |
WO (1) | WO2016168758A1 (zh) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6721505B2 (ja) | 2013-09-05 | 2020-07-15 | アイジーエム バイオサイエンシズ インコーポレイテッド | 定常領域が修飾された(constant chain modified)二重特異性五価及び六価Ig−M抗体 |
CN105992772A (zh) | 2014-02-10 | 2016-10-05 | Igm生命科学股份有限公司 | IgA多特异性结合分子 |
ES2887299T3 (es) | 2014-04-03 | 2021-12-22 | Igm Biosciences Inc | Cadena J modificada |
EP3750918A1 (en) | 2015-01-20 | 2020-12-16 | IGM Biosciences, Inc. | Tumor necrosis factor (tnf) superfamily receptor binding molecules and uses thereof |
DK3265575T3 (da) | 2015-03-04 | 2021-05-31 | Igm Biosciences Inc | Cd20-bindende molekyler og anvendelser deraf |
AU2016238246B2 (en) | 2015-03-25 | 2021-05-13 | Igm Biosciences, Inc. | Multi-valent hepatitis B virus antigen binding molecules and uses thereof |
JP6811723B2 (ja) * | 2015-04-17 | 2021-01-13 | アイジーエム バイオサイエンシズ インコーポレイテッド | 多価ヒト免疫不全ウイルス抗原結合分子およびその使用方法 |
US10618978B2 (en) | 2015-09-30 | 2020-04-14 | Igm Biosciences, Inc. | Binding molecules with modified J-chain |
US11639389B2 (en) | 2015-09-30 | 2023-05-02 | Igm Biosciences, Inc. | Binding molecules with modified J-chain |
KR102343742B1 (ko) | 2016-05-09 | 2021-12-24 | 아이쥐엠 바이오사이언스 인코포레이티드 | 항-pd-l1 항체 |
CN110536900B (zh) | 2017-04-07 | 2024-06-11 | Igm生物科学股份有限公司 | 调节补体依赖性细胞溶解效应子功能的修饰的人igm恒定区 |
KR102324568B1 (ko) * | 2017-06-21 | 2021-11-10 | 길리애드 사이언시즈, 인코포레이티드 | HIV gp120 및 CD3을 표적화하는 다중특이적 항체 |
JP2021507717A (ja) * | 2017-12-18 | 2021-02-25 | ビーブ、ヘルスケア、ユーケー、(ナンバー5)、リミテッドViiv Healthcare Uk (No.5) Limited | 抗原結合性ポリペプチド |
JP7376490B2 (ja) | 2018-03-01 | 2023-11-08 | アイジーエム バイオサイエンシズ インコーポレイテッド | IgM血清半減期に影響を及ぼすIgM Fc及びJ鎖の変異 |
JP2021524451A (ja) * | 2018-05-18 | 2021-09-13 | マクロジェニクス,インコーポレーテッド | 最適化済みgp41結合分子及びその使用 |
CA3102859A1 (en) | 2018-07-03 | 2020-01-09 | Gilead Sciences, Inc. | Antibodies that target hiv gp120 and methods of use |
US20210292396A1 (en) * | 2018-07-27 | 2021-09-23 | International Aids Vaccine Initiative | Enginerred antibodies to hiv env |
EP3849607A4 (en) * | 2018-09-13 | 2022-06-22 | Children's National Medical Center | CELLS COMPRISING ANTIBODIES TARGETING HUMAN IMMUNODEFICIENCY VIRUS AND METHODS OF PREPARING THEM AND USE THEREOF |
WO2020082045A1 (en) * | 2018-10-19 | 2020-04-23 | University Of Maryland, College Park | Multispecfic anti-hiv antibodies |
US20220018856A1 (en) * | 2018-11-22 | 2022-01-20 | Fujirebio Inc. | Antibody conjugate |
CN109776683B (zh) * | 2019-03-19 | 2020-04-07 | 益科思特(北京)医药科技发展有限公司 | 一种双特异性抗体及其制备方法与应用 |
TW202116800A (zh) * | 2019-07-08 | 2021-05-01 | 美國洛克菲勒大學 | 多反應性降低之抗hiv疫苗抗體 |
JP2022544405A (ja) | 2019-08-15 | 2022-10-18 | アイジーエム バイオサイエンシズ インコーポレイテッド | 免疫刺激性多量体型結合分子 |
MX2022013334A (es) | 2020-04-22 | 2022-12-06 | Igm Biosciences Inc | Moleculas de union multimerica de agonistas de pd-1. |
BR112023003366A2 (pt) * | 2020-08-25 | 2023-05-09 | Gilead Sciences Inc | Moléculas multiespecíficas de ligação ao antígeno que têm como alvo hiv e métodos de uso |
CN113461811A (zh) * | 2021-06-30 | 2021-10-01 | 复旦大学 | 一种双特异性抗hiv-1抗体 |
CN116589566A (zh) * | 2022-11-18 | 2023-08-15 | 昆明医科大学第一附属医院 | 一种HIV-1中和抗体的改造重组单克隆IgM抗体及其应用 |
Family Cites Families (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
EP0463151B1 (en) | 1990-01-12 | 1996-06-12 | Cell Genesys, Inc. | Generation of xenogeneic antibodies |
JP3463143B2 (ja) * | 1995-12-18 | 2003-11-05 | 秀親 岡田 | 糖鎖認識抗体及びhiv感染症治療剤 |
TW505656B (en) | 1995-12-18 | 2002-10-11 | Otsuka Pharma Co Ltd | Sugar-chain-recognizing antibodies and pharmaceutical composition for HIV infectious diseases |
US5834597A (en) | 1996-05-20 | 1998-11-10 | Protein Design Labs, Inc. | Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same |
DE19622088A1 (de) * | 1996-05-31 | 1997-12-04 | Boehringer Mannheim Gmbh | Anti-HIV-Antikörper als Kontrollproben |
AU740918B2 (en) * | 1997-01-10 | 2001-11-15 | Plantibodies Corporation | Novel epithelial tissue targeting agent |
JP2002505097A (ja) | 1998-03-03 | 2002-02-19 | アブジェニックス インク. | 治療薬としてのcd147結合分子 |
CN101016543A (zh) * | 2000-11-17 | 2007-08-15 | 罗切斯特大学 | 筛选编码抗原特异性免疫球蛋白分子或其抗原特异性片段的多核苷酸的方法 |
EP1533320B1 (en) * | 2002-07-01 | 2009-02-18 | Nagoya Industrial Science Research Institute | HUMAN IgM ANTIBODY INDUCING APOPTOSIS IN HIV-INFECTED CELLS AND REMEDY FOR HIV-INFECTION |
JP4939929B2 (ja) * | 2003-03-26 | 2012-05-30 | ポール,サッドヒル | タンパク質分解抗体および共有結合抗体 |
US20050014932A1 (en) | 2003-05-15 | 2005-01-20 | Iogenetics, Llc | Targeted biocides |
US7513893B2 (en) * | 2004-03-12 | 2009-04-07 | Abraham Ebbie Soroudi | Device and method for treatment of eyelid diseases |
US20080181892A1 (en) * | 2004-08-11 | 2008-07-31 | Trubion Pharmaceuticals | Binding Domain Fusion Protein |
WO2006044410A2 (en) | 2004-10-14 | 2006-04-27 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | A32 monoclonal antibody fusion proteins for use as hiv inhibitors and vaccines |
DK1814913T3 (en) | 2004-11-05 | 2015-09-28 | Univ Leland Stanford Junior | ANTIBODY-INDUCED CELL membrane damage. |
EP1879921B1 (en) | 2005-05-12 | 2011-04-27 | Crucell Holland B.V. | Host cell specific binding molecules capable of neutralizing viruses and uses thereof |
ES2372359T3 (es) * | 2007-04-20 | 2012-01-19 | F. Hoffmann-La Roche Ag | Detección de infecciones primarias por patógenos. |
WO2010036339A2 (en) | 2008-09-25 | 2010-04-01 | Duke University | A method of detecting antibodies and antibody-hiv virion complexes |
JP5946766B2 (ja) * | 2009-07-03 | 2016-07-06 | ビオノール イミュノ エーエスBionor Immuno As | Hivワクチン組成物における使用又は診断手段としての使用のためのhiv関連ペプチドの組合せ又は融合物 |
US20110189183A1 (en) | 2009-09-18 | 2011-08-04 | Robert Anthony Williamson | Antibodies against candida, collections thereof and methods of use |
WO2011038290A2 (en) * | 2009-09-25 | 2011-03-31 | The U. S. A., As Represented By The Secretary, Department Of Health And Human Services | Neutralizing antibodies to hiv-1 and their use |
AU2011215684A1 (en) * | 2010-02-12 | 2012-08-30 | Research Corporation Technologies | Multimeric proteins comprising immunoglobulin constant domains |
WO2012106578A1 (en) * | 2011-02-04 | 2012-08-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | HIV NEUTRALIZING ANTIBODIES HAVING MUTATIONS IN CONSTANT DOMAIN (Fc) |
WO2013049254A1 (en) | 2011-09-26 | 2013-04-04 | Jn Biosciences Llc | Hybrid constant regions |
WO2013070776A1 (en) | 2011-11-07 | 2013-05-16 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Neutralizing gp41 antibodies and their use |
CN108676091B (zh) | 2011-12-08 | 2022-04-01 | 美国政府(由卫生和人类服务部的部长所代表) | Hiv-1的中和抗体及其用途 |
EP2807181A1 (en) * | 2012-01-26 | 2014-12-03 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Vaccine compositions for hiv prevention and treatment |
CA2863714C (en) | 2012-02-08 | 2022-07-05 | Igm Biosciences, Inc. | Cdim binding proteins and uses thereof |
US20150044137A1 (en) | 2012-03-23 | 2015-02-12 | The United States of America, as represented by the Secretary, Dep. of Health Care Human Services | Neutralizing antibodies to hiv-1 and their use |
EP2880057A4 (en) * | 2012-08-02 | 2016-03-23 | Jn Biosciences Llc | MULTIMERIZED FUSION ANTIBODIES OR PROTEINS THROUGH THE MUTATION OF A CYSTEINE AND A PIECE OF TAIL |
EP2882455A4 (en) * | 2012-08-08 | 2016-03-23 | Network Immunology Inc | METHOD FOR INDUCING AN IMMUNE RESPONSE |
JP2014124186A (ja) * | 2012-12-26 | 2014-07-07 | Industrial Technology Research Institute | 多価抗体フラグメントおよびその三量体化複合体 |
JP6721505B2 (ja) | 2013-09-05 | 2020-07-15 | アイジーエム バイオサイエンシズ インコーポレイテッド | 定常領域が修飾された(constant chain modified)二重特異性五価及び六価Ig−M抗体 |
US10167333B2 (en) | 2014-01-16 | 2019-01-01 | Mario Umberto Francesco Mondelli | Neutralizing human monoclonal antibodies against hepatitis B virus surface antigen |
CN105992772A (zh) | 2014-02-10 | 2016-10-05 | Igm生命科学股份有限公司 | IgA多特异性结合分子 |
ES2887299T3 (es) | 2014-04-03 | 2021-12-22 | Igm Biosciences Inc | Cadena J modificada |
EP3750918A1 (en) | 2015-01-20 | 2020-12-16 | IGM Biosciences, Inc. | Tumor necrosis factor (tnf) superfamily receptor binding molecules and uses thereof |
DK3265575T3 (da) | 2015-03-04 | 2021-05-31 | Igm Biosciences Inc | Cd20-bindende molekyler og anvendelser deraf |
AU2016238246B2 (en) | 2015-03-25 | 2021-05-13 | Igm Biosciences, Inc. | Multi-valent hepatitis B virus antigen binding molecules and uses thereof |
JP6811723B2 (ja) * | 2015-04-17 | 2021-01-13 | アイジーエム バイオサイエンシズ インコーポレイテッド | 多価ヒト免疫不全ウイルス抗原結合分子およびその使用方法 |
US11639389B2 (en) | 2015-09-30 | 2023-05-02 | Igm Biosciences, Inc. | Binding molecules with modified J-chain |
US10618978B2 (en) | 2015-09-30 | 2020-04-14 | Igm Biosciences, Inc. | Binding molecules with modified J-chain |
KR102343742B1 (ko) | 2016-05-09 | 2021-12-24 | 아이쥐엠 바이오사이언스 인코포레이티드 | 항-pd-l1 항체 |
CA3030634A1 (en) | 2016-07-20 | 2018-01-25 | Igm Biosciences, Inc. | Multimeric cd137/4-1bb binding molecules and uses thereof |
WO2018017888A1 (en) | 2016-07-20 | 2018-01-25 | Igm Biosciences, Inc. | Multimeric ox40 binding molecules and uses thereof |
CA3030640A1 (en) | 2016-07-20 | 2018-01-25 | Igm Biosciences, Inc. | Multimeric cd40 binding molecules and uses thereof |
EP3487299A4 (en) | 2016-07-20 | 2020-03-11 | IGM Biosciences, Inc. | MULTIMERICAL GITR FIXING MOLECULES |
CN110536900B (zh) | 2017-04-07 | 2024-06-11 | Igm生物科学股份有限公司 | 调节补体依赖性细胞溶解效应子功能的修饰的人igm恒定区 |
CN111757941A (zh) | 2018-02-26 | 2020-10-09 | Igm生物科学股份有限公司 | 多聚体抗dr5结合分子与化学治疗剂联合用于治疗癌症的用途 |
JP7376490B2 (ja) | 2018-03-01 | 2023-11-08 | アイジーエム バイオサイエンシズ インコーポレイテッド | IgM血清半減期に影響を及ぼすIgM Fc及びJ鎖の変異 |
MX2021004660A (es) | 2018-10-23 | 2021-05-28 | Igm Biosciences Inc | Moleculas de union multivalentes a base de igm- e iga-fc. |
US20220106398A1 (en) | 2019-02-08 | 2022-04-07 | Igm Biosciences, Inc. | Anti-gitr antigen-binding domains and uses thereof |
-
2016
- 2016-04-15 JP JP2017554329A patent/JP6811723B2/ja active Active
- 2016-04-15 CA CA2983034A patent/CA2983034A1/en active Pending
- 2016-04-15 AU AU2016249404A patent/AU2016249404B2/en active Active
- 2016-04-15 WO PCT/US2016/027979 patent/WO2016168758A1/en active Application Filing
- 2016-04-15 US US15/566,485 patent/US10570191B2/en active Active
- 2016-04-15 EP EP16780944.1A patent/EP3283112A4/en active Pending
- 2016-04-15 CN CN201680035419.8A patent/CN107847591B/zh active Active
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2018
- 2018-04-27 HK HK18105481.5A patent/HK1245675A1/zh unknown
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2020
- 2020-01-07 US US16/736,327 patent/US11192941B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP3283112A4 (en) | 2018-12-05 |
WO2016168758A1 (en) | 2016-10-20 |
JP6811723B2 (ja) | 2021-01-13 |
CN107847591B (zh) | 2023-07-28 |
CN107847591A (zh) | 2018-03-27 |
AU2016249404B2 (en) | 2021-01-21 |
US11192941B2 (en) | 2021-12-07 |
JP2018512863A (ja) | 2018-05-24 |
AU2016249404A1 (en) | 2017-11-23 |
US10570191B2 (en) | 2020-02-25 |
US20200377577A1 (en) | 2020-12-03 |
EP3283112A1 (en) | 2018-02-21 |
US20180118816A1 (en) | 2018-05-03 |
CA2983034A1 (en) | 2016-10-20 |
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